Research Topics
Genomes and Genes | V DuprezSummaryCountry: France Publications
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Publications
Physical and functional interaction between p72(syk) and erythropoietin receptorV Duprez
Institut National de la Sante et de la Recherche Medicale, Unité 363, ICGM, Hopital Cochin, 27 rue du Faubourg Saint Jacques, Paris, France
J Biol Chem 273:33985-90. 1998..We propose that in addition to Jak2, Syk protein kinase may be a component of EpoR signaling...
Abnormal erythropoietin (Epo) gene expression in the murine erythroleukemia IW32 cells results from a rearrangement between the G-protein beta2 subunit gene and the Epo geneS Chretien
Institut National de la Transfusion Sanguine, Paris, France
Oncogene 15:1995-9. 1997..This resulting abnormal cDNA allows the expression of a normal Epo protein...
Thrombopoietin stimulates cortactin translocation to the cytoskeleton independently of tyrosine phosphorylationI Lopez
Departement d Hematologie, AP HP, Hopital Cochin, 27 rue du Faubourg Saint Jacques, F75679 Paris, Cedex 14, France
Biochem J 356:875-81. 2001..These data suggest that tyrosine phosphorylation is not required for cortactin translocation to the detergent-insoluble compartment. Furthermore, TPO activates, through its receptor c-Mpl, a signalling pathway to the cytoskeleton...
Coupling of heterotrimeric Gi proteins to the erythropoietin receptorC Guillard
INSERM, U 363 and CNRS-UPR 0415, , 75014 Paris, France
J Biol Chem 276:2007-14. 2001..Receptor activation leads to the activation and dissociation of Gi from the receptor, suggesting a functional role of Gi protein in Epo signal transduction...
