Nicolas Dulphy

Summary

Country: France

Publications

  1. doi request reprint NKG2D ligands expression and NKG2D-mediated NK activity in Sezary patients
    Nicolas Dulphy
    Institut National de la Santé et de la Recherche Médicale U662, Institut Universitaire d Hematologie, Centre Hayem, Hopital Saint Louis, Paris, France
    J Invest Dermatol 129:359-64. 2009
  2. ncbi request reprint An unusual CD56(bright) CD16(low) NK cell subset dominates the early posttransplant period following HLA-matched hematopoietic stem cell transplantation
    Nicolas Dulphy
    Institut National de la Sante et de la Recherche Medicale, U662, Paris, France
    J Immunol 181:2227-37. 2008
  3. doi request reprint MICA-129 genotype, soluble MICA, and anti-MICA antibodies as biomarkers of chronic graft-versus-host disease
    Wahid Boukouaci
    Laboratoire d Immunologie et d Histocompatibilité, Centre d Innovations Biomédicales Hématologie Oncologie Greffe CIB HOG, Institut Universitaire d Hématologie IUH, and INSERM, UMRS, 940, Hopital Saint Louis, Paris, France
    Blood 114:5216-24. 2009
  4. doi request reprint NK-cell education is shaped by donor HLA genotype after unrelated allogeneic hematopoietic stem cell transplantation
    Philippe Haas
    INSERM, Paris, France
    Blood 117:1021-9. 2011
  5. ncbi request reprint CD4+NKG2D+ T cells in Crohn's disease mediate inflammatory and cytotoxic responses through MICA interactions
    Matthieu Allez
    Service de Gastroenterologie, Hopital Saint Louis, Paris, France INSERM Unité 662, Hopital Saint Louis, Paris, France
    Gastroenterology 132:2346-58. 2007
  6. doi request reprint Activation of the receptor NKG2D leads to production of Th17 cytokines in CD4+ T cells of patients with Crohn's disease
    Benjamin Pariente
    INSERM, Equipe AVENIR U940 Hôpital Saint Louis, and Centre de Recherche des Cordeliers, Universite Pierre et Marie Curie Paris 6, Paris, France
    Gastroenterology 141:217-26, 226.e1-2. 2011
  7. doi request reprint At diagnosis, diffuse large B-cell lymphoma patients show impaired rituximab-mediated NK-cell cytotoxicity
    Anne Danielou-Lazareth
    Assistance Publique Hopitaux de Paris AP HP, Hopital Saint Louis, Service d Hématologie Oncologie Adulte, Paris, France
    Eur J Immunol 43:1383-8. 2013
  8. ncbi request reprint BCR/ABL oncogene directly controls MHC class I chain-related molecule A expression in chronic myelogenous leukemia
    Nicolas Boissel
    Institut National de la Sante et de la Recherche Medicale, Unité 622, Centre d Investigations Biomedicales, Laboratoire d Immunologie et d Histocompatibilité, Hopital Saint Louis, Paris, France
    J Immunol 176:5108-16. 2006
  9. ncbi request reprint Oxidative stress mediates a reduced expression of the activating receptor NKG2D in NK cells from end-stage renal disease patients
    Marie Noelle Peraldi
    Institut National de la Sante et de la Recherche Medicale, U662, Paris, France
    J Immunol 182:1696-705. 2009
  10. ncbi request reprint Intermediate maturation of Mycobacterium tuberculosis LAM-activated human dendritic cells
    Nicolas Dulphy
    INSERM, U662, Institut Universitaire d Hematologie, Universite Paris VII, and Laboratoire d Immunologie et d Histocompatibilité, Centre d Investigation Biomédicales, AP HP, Hôpital Sait Louis, Paris, F 75010, France
    Cell Microbiol 9:1412-25. 2007

Collaborators

Detail Information

Publications13

  1. doi request reprint NKG2D ligands expression and NKG2D-mediated NK activity in Sezary patients
    Nicolas Dulphy
    Institut National de la Santé et de la Recherche Médicale U662, Institut Universitaire d Hematologie, Centre Hayem, Hopital Saint Louis, Paris, France
    J Invest Dermatol 129:359-64. 2009
    ..Altogether, these data could suggest that stimulating NK function in SS patients may be a promising strategy to reduce tumor invasion...
  2. ncbi request reprint An unusual CD56(bright) CD16(low) NK cell subset dominates the early posttransplant period following HLA-matched hematopoietic stem cell transplantation
    Nicolas Dulphy
    Institut National de la Sante et de la Recherche Medicale, U662, Paris, France
    J Immunol 181:2227-37. 2008
    ..Altogether, CD56(bright) NK cells postallogeneic HSCT exhibit peculiar phenotypic and functional properties. Functional interactions between this subset and T cells may be important in shaping the immune response after HSCT...
  3. doi request reprint MICA-129 genotype, soluble MICA, and anti-MICA antibodies as biomarkers of chronic graft-versus-host disease
    Wahid Boukouaci
    Laboratoire d Immunologie et d Histocompatibilité, Centre d Innovations Biomédicales Hématologie Oncologie Greffe CIB HOG, Institut Universitaire d Hématologie IUH, and INSERM, UMRS, 940, Hopital Saint Louis, Paris, France
    Blood 114:5216-24. 2009
    ..Altogether, these data suggest that the studied MICA genotype and phenotype specificities could be used as relevant biomarkers for cGVHD monitoring...
  4. doi request reprint NK-cell education is shaped by donor HLA genotype after unrelated allogeneic hematopoietic stem cell transplantation
    Philippe Haas
    INSERM, Paris, France
    Blood 117:1021-9. 2011
    ..This donor-ligand-driven NK-cell education model would suggest a sustained graft-versus-leukemia effect after HLA-mismatched HSCT...
  5. ncbi request reprint CD4+NKG2D+ T cells in Crohn's disease mediate inflammatory and cytotoxic responses through MICA interactions
    Matthieu Allez
    Service de Gastroenterologie, Hopital Saint Louis, Paris, France INSERM Unité 662, Hopital Saint Louis, Paris, France
    Gastroenterology 132:2346-58. 2007
    ..We examined the role of MICA-NKG2D interactions in the activation of T lymphocytes in CD...
  6. doi request reprint Activation of the receptor NKG2D leads to production of Th17 cytokines in CD4+ T cells of patients with Crohn's disease
    Benjamin Pariente
    INSERM, Equipe AVENIR U940 Hôpital Saint Louis, and Centre de Recherche des Cordeliers, Universite Pierre et Marie Curie Paris 6, Paris, France
    Gastroenterology 141:217-26, 226.e1-2. 2011
    ..We investigated the Th17 cytokines produced by T cells that express NKG2D in blood and intestinal mucosa samples from patients with CD...
  7. doi request reprint At diagnosis, diffuse large B-cell lymphoma patients show impaired rituximab-mediated NK-cell cytotoxicity
    Anne Danielou-Lazareth
    Assistance Publique Hopitaux de Paris AP HP, Hopital Saint Louis, Service d Hématologie Oncologie Adulte, Paris, France
    Eur J Immunol 43:1383-8. 2013
    ..These results suggest that rituximab-induced NK-cell ADCC could be defective in some DLBCL patients at diagnosis. These patients should be closely monitored and attempts made to improve their NK-cell function...
  8. ncbi request reprint BCR/ABL oncogene directly controls MHC class I chain-related molecule A expression in chronic myelogenous leukemia
    Nicolas Boissel
    Institut National de la Sante et de la Recherche Medicale, Unité 622, Centre d Investigations Biomedicales, Laboratoire d Immunologie et d Histocompatibilité, Hopital Saint Louis, Paris, France
    J Immunol 176:5108-16. 2006
    ..These data provide evidence for direct control of MICA expression by an oncogene in human malignancy and indicate that posttranscriptional mechanisms may participate in the regulation of MICA expression...
  9. ncbi request reprint Oxidative stress mediates a reduced expression of the activating receptor NKG2D in NK cells from end-stage renal disease patients
    Marie Noelle Peraldi
    Institut National de la Sante et de la Recherche Medicale, U662, Paris, France
    J Immunol 182:1696-705. 2009
    ..Taken together, these studies suggest for the first time that both low NKG2D expression and up-regulation of its ligand MICA are related to ROS production and may be involved in the immune deficiency of ESRD patients...
  10. ncbi request reprint Intermediate maturation of Mycobacterium tuberculosis LAM-activated human dendritic cells
    Nicolas Dulphy
    INSERM, U662, Institut Universitaire d Hematologie, Universite Paris VII, and Laboratoire d Immunologie et d Histocompatibilité, Centre d Investigation Biomédicales, AP HP, Hôpital Sait Louis, Paris, F 75010, France
    Cell Microbiol 9:1412-25. 2007
    ..tuberculosis...
  11. ncbi request reprint Early-onset ankylosing spondylitis is associated with a functional MICA polymorphism
    Habiba Amroun
    Laboratoire d Immunologie et d Histocompatibilité CIB HOB, AP HP, IUH and INSERM U662, Hopital Saint Louis, Paris, France
    Hum Immunol 66:1057-61. 2005
    ..02) independent of HLA-B27 status. These data suggest a potential role for a functionally relevant MICA gene polymorphism in autoimmune/inflammatory disease susceptibility...
  12. pmc Natural killer cell function, an important target for infection and tumor protection, is impaired in type 2 diabetes
    Jeannig Berrou
    Institut National de la Sante et de la Recherche Medicale INSERM, UMR 940, Paris, France
    PLoS ONE 8:e62418. 2013
    ..These defects may contribute to susceptibility to infections and malignancies and could be targetted therapeutically...
  13. ncbi request reprint Association of HLA-E polymorphism with severe bacterial infection and early transplant-related mortality in matched unrelated bone marrow transplantation
    Ryad Tamouza
    Laboratoire d Immunologie et d Histocompatibilité AP HP, IUH, and INSERM U662, Hopital Saint Louis, Paris, France
    Transplantation 80:140-4. 2005
    ..20; P=0.03 and HR=2.12, P=0.048, respectively), suggesting that homozygous state for HLA-E*0101 allele is a risk factor for early severe bacterial infections and TRM in UD-BMT...