Research Topics
Species | François DucraySummaryCountry: France Publications
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Detail Information
Publications
Anaplastic oligodendrogliomas with 1p19q codeletion have a proneural gene expression profileFrançois Ducray
Unite Inserm U711, Universite Paris VI, 47 83 boulevard de l Hopital, 75013 Paris, France
Mol Cancer 7:41. 2008..We performed a microarray gene expression study of four high grade gliomas with 1p19q codeletion and nine with EGFR amplification, identified by CGH-array...
[Biology of gliomas]F Ducray
Service de Neurologie B, Hopital Neurologique, 59, boulevard Pinel, 69391 Lyon cedex 03, France
Cancer Radiother 12:663-8. 2008..These advances are facilitating the establishment of a more precise, molecular-based, classification of gliomas and are leading to new therapeutic strategies directed against the key molecular events implicated in gliomas oncogenesis...
Methylation profiling identifies 2 groups of gliomas according to their tumorigenesisJulien Laffaire
Universite Pierre et Marie Curie Paris 6, Centre de Recherche de l Institut du Cerveau et de la Moëlle épinière CRICM UMR S975, 75013 Paris, France
Neuro Oncol 13:84-98. 2011..Finally, we identified several hypermethylated and downregulated genes that may be associated with LGG and GBM oncogenesis, LGG oncogenesis, 1p19q codeleted LGG oncogenesis, and GBM oncogenesis...
Diagnostic and prognostic value of alpha internexin expression in a series of 409 gliomasFrançois Ducray
Hopital Neurologique, Service de Neurologie B, Lyon, France
Eur J Cancer 47:802-8. 2011..1 versus 10.2 months, p=0.0007) and longer OS (124.6 versus 20.6 months, p=0.0001). In conclusion, INA expression is a fast, cheap and reliable prognostic marker, and represents a surrogate marker for 1p19q complete codeletion...
TP53 codon 72 polymorphism, p53 expression, and 1p/19q status in oligodendroglial tumorsAhmed Idbaih
INSERM, Unité 711, Groupe Hospitalier Pitie Salpetriere, 47 83 boulevard de l Hopital, 75013 Paris, France
Cancer Genet Cytogenet 177:103-7. 2007..This suggests no association between oligodendroglial tumors and the SNP in codon 72 of TP53. Similarly, no correlation was found among the TP53 codon 72 polymorphism and prognosis, p53 expression, and chromosomes 1p and 19q status...
Predictive and prognostic factors for gliomasFrançois Ducray
Hopital Neurologique, Service de Neurologie B, Lyon, France
Expert Rev Anticancer Ther 11:781-9. 2011..Recently, integrated genomic, transcriptomic and epigenetic studies have unraveled new glioblastoma subgroups that further refines the molecular classification of these tumors. Such an approach should be extended to lower grade gliomas...
Diagnostic and prognostic markers in gliomasFrançois Ducray
Unité Inserm U842, Service de Neurologie B, Hopital Neurologique, Universite Claude Bernard Lyon 1, Lyon, France
Curr Opin Oncol 21:537-42. 2009....
Chemotherapy in low-grade gliomasAurélien Viaccoz
Service de Neuro Oncologie, Hopital Neurologique, Hospices Civils de Lyon, Lyon, France
Curr Opin Oncol 24:694-701. 2012..This review summarizes the recent studies in adults' diffuse low-grade gliomas (LGGs) chemotherapy, including response assessment and potential predictive biomarkers of chemosensitivity...
