Jean Charles Duclos-Vallée

Summary

Country: France

Publications

  1. pmc A 10 year follow up study of patients transplanted for autoimmune hepatitis: histological recurrence precedes clinical and biochemical recurrence
    J C Duclos-Vallee
    Centre Hepato Biliaire, EPI 99 41 et UPRES 1596, Hopital Paul Brousse, Villejuif, France
    Gut 52:893-7. 2003
  2. ncbi request reprint [Liver transplantation in patients with HIV: indications, limits, perspectives]
    Didier Samuel
    Centre Hepatobiliaire, UPRES 3541, Formation Associée de Recherche Association Claude Bernard Virus et Transplantation, Universite Paris Sud
    Gastroenterol Clin Biol 27:372-4. 2003
  3. ncbi request reprint Recurrence of autoimmune hepatitis, primary biliary cirrhosis and primary sclerosing cholangitis after liver transplantation
    Jean Charles Duclos-Vallée
    Centre Hepato Biliaire, UPRES EA 3541, Hopital Paul Brousse, Assistance Publique Hopitaux de Paris, Villejuif, France
    Acta Gastroenterol Belg 68:331-6. 2005
  4. ncbi request reprint [Wilson's disease]
    Jean Charles Duclos-Vallée
    Département des maladies du foie, centre hépato biliaire et unité Inserm U 785, Hopital Paul Brousse, Villejuif
    Rev Prat 56:469-74. 2006
  5. ncbi request reprint [Current trend: autoimmune hepatitis]
    Jean Charles Duclos-Vallée
    Département des maladies du foie, Centre Hépato Biliaire et UPRES 3541, Hopital Paul Brousse, 94804 Villejuif Cedex
    Gastroenterol Clin Biol 29:1236-43; quiz 1234-5. 2005
  6. ncbi request reprint Remission with ursodeoxycholic acid of type 1 autoimmune hepatitis resistant to azathioprine and steroids
    Jean Charles Duclos-Vallée
    Centre Hépato Biliaire and UPRES 3541, Hopital Paul Brousse, Villejuif
    Gastroenterol Clin Biol 29:1173-6. 2005
  7. doi request reprint [Liver transplantation in patients with hepatitis B virus, hepatitis C virus, or human immunodeficiency virus]
    Jean Charles Duclos-Vallée
    Centre Hepato Biliaire, INSERM U785, Hopital Paul Brousse, Universite Paris Sud, 12 14 avenue Paul Vaillant Couturier, Villejuif, France
    Presse Med 38:1281-9. 2009
  8. ncbi request reprint Survival and recurrence of hepatitis C after liver transplantation in patients coinfected with human immunodeficiency virus and hepatitis C virus
    Jean Charles Duclos-Vallée
    Centre Hepato Biliaire, AP HP Hopital Paul Brousse, Villejuif, France
    Hepatology 47:407-17. 2008
  9. ncbi request reprint Hepatitis C virus viral recurrence and liver mitochondrial damage after liver transplantation in HIV-HCV co-infected patients
    Jean Charles Duclos-Vallée
    Centre Hépato Biliaire Hôpital Paul Brousse, Assistance Publique Hopitaux de Paris, 94804 Villejuif, France
    J Hepatol 42:341-9. 2005
  10. ncbi request reprint [Autoimmune hepatitis. Physiopathologic, clinical, histological, and therapeutic features]
    J C Duclos-Vallee
    Centre Hepato Biliaire, EPI 99 41 et UPRES 1596, Hopital Paul Brousse, 14, avenue Paul Vaillant Couturier, 94804 Villejuif
    Ann Med Interne (Paris) 152:371-82. 2001

Collaborators

Detail Information

Publications44

  1. pmc A 10 year follow up study of patients transplanted for autoimmune hepatitis: histological recurrence precedes clinical and biochemical recurrence
    J C Duclos-Vallee
    Centre Hepato Biliaire, EPI 99 41 et UPRES 1596, Hopital Paul Brousse, Villejuif, France
    Gut 52:893-7. 2003
    ..The aim of the present study was to examine the clinical and histological outcome more than 10 years after OLT for AIH...
  2. ncbi request reprint [Liver transplantation in patients with HIV: indications, limits, perspectives]
    Didier Samuel
    Centre Hepatobiliaire, UPRES 3541, Formation Associée de Recherche Association Claude Bernard Virus et Transplantation, Universite Paris Sud
    Gastroenterol Clin Biol 27:372-4. 2003
  3. ncbi request reprint Recurrence of autoimmune hepatitis, primary biliary cirrhosis and primary sclerosing cholangitis after liver transplantation
    Jean Charles Duclos-Vallée
    Centre Hepato Biliaire, UPRES EA 3541, Hopital Paul Brousse, Assistance Publique Hopitaux de Paris, Villejuif, France
    Acta Gastroenterol Belg 68:331-6. 2005
    ..We would like with this overview to describe the different pattern of recurrence of these autoimmune liver disease, their potential influence on the liver graft and their therapeutic management...
  4. ncbi request reprint [Wilson's disease]
    Jean Charles Duclos-Vallée
    Département des maladies du foie, centre hépato biliaire et unité Inserm U 785, Hopital Paul Brousse, Villejuif
    Rev Prat 56:469-74. 2006
    ..Liver transplantation is the therapy to patients with hepatic fulminant course, or in those with relentless progression of hepatic dysfunction in spite of medical therapy...
  5. ncbi request reprint [Current trend: autoimmune hepatitis]
    Jean Charles Duclos-Vallée
    Département des maladies du foie, Centre Hépato Biliaire et UPRES 3541, Hopital Paul Brousse, 94804 Villejuif Cedex
    Gastroenterol Clin Biol 29:1236-43; quiz 1234-5. 2005
  6. ncbi request reprint Remission with ursodeoxycholic acid of type 1 autoimmune hepatitis resistant to azathioprine and steroids
    Jean Charles Duclos-Vallée
    Centre Hépato Biliaire and UPRES 3541, Hopital Paul Brousse, Villejuif
    Gastroenterol Clin Biol 29:1173-6. 2005
    ....
  7. doi request reprint [Liver transplantation in patients with hepatitis B virus, hepatitis C virus, or human immunodeficiency virus]
    Jean Charles Duclos-Vallée
    Centre Hepato Biliaire, INSERM U785, Hopital Paul Brousse, Universite Paris Sud, 12 14 avenue Paul Vaillant Couturier, Villejuif, France
    Presse Med 38:1281-9. 2009
    ..In HIV/HCV coinfected patients, however, the recurrence of HCV infection is more severe than in patients with HCV alone and survival thus lower. Very early anti-HCV therapy must be discussed...
  8. ncbi request reprint Survival and recurrence of hepatitis C after liver transplantation in patients coinfected with human immunodeficiency virus and hepatitis C virus
    Jean Charles Duclos-Vallée
    Centre Hepato Biliaire, AP HP Hopital Paul Brousse, Villejuif, France
    Hepatology 47:407-17. 2008
    ..03; risk ratio, 1.08; 95% confidence interval, 1.01, 1.15). Using the Kaplan-Meier method, the progression to fibrosis >or= F2 was significantly higher in the coinfected group (P < 0.0001)...
  9. ncbi request reprint Hepatitis C virus viral recurrence and liver mitochondrial damage after liver transplantation in HIV-HCV co-infected patients
    Jean Charles Duclos-Vallée
    Centre Hépato Biliaire Hôpital Paul Brousse, Assistance Publique Hopitaux de Paris, 94804 Villejuif, France
    J Hepatol 42:341-9. 2005
    ..We report the Paul Brousse Hospital experience of transplantation for end stage cirrhosis in HIV-HCV co-infected patients...
  10. ncbi request reprint [Autoimmune hepatitis. Physiopathologic, clinical, histological, and therapeutic features]
    J C Duclos-Vallee
    Centre Hepato Biliaire, EPI 99 41 et UPRES 1596, Hopital Paul Brousse, 14, avenue Paul Vaillant Couturier, 94804 Villejuif
    Ann Med Interne (Paris) 152:371-82. 2001
    ..If relapse or non response occur, other immunosuppressive therapy such as cyclosporin may be useful. Liver transplantation is reserved for (sub)fulminant forms and end stage liver disease...
  11. pmc Practical management of boceprevir and immunosuppressive therapy in liver transplant recipients with hepatitis C virus recurrence
    Audrey Coilly
    AP HP, Hopital Paul Brousse, Centre Hepato Biliaire, Villejuif, France
    Antimicrob Agents Chemother 56:5728-34. 2012
    ..64 ± 0.35 log(10) IU/ml). These preliminary results in liver transplant patients with HCV recurrence demonstrate the feasibility and safety of coadministration of boceprevir and IT...
  12. doi request reprint Successful anti-hepatitis C virus therapy with telaprevir in an HIV/hepatitis C virus co-infected patient with a severe recurrence of hepatitis C virus infection on the liver graft
    Teresa M Antonini
    aAP HP, Hopital Paul Brousse, Centre Hépato Biliaire bUniversity Paris Sud, UMR S 785 cInserm, Unite 785, Villejuif dAP HP, HôpitalBicêtre, Pharmacie Clinique eAP HP, Hopital Bicetre, Service de Medecine Interne, Immunologie et Maladies Infectieuses, Le Kremlin Bicêtre fAP HP Hôpital Paul Brousse, Service de Virologie gAP HP, Hopital Paul Brousse, Service Anatomie Pathologique hAP HP, Hopital Paul Brousse, Pharmacie Clinique, Villejuif iAP HP, GH Xavier Bichat Claude Bernard, Laboratoire de Toxicologie et Pharmacocinétique jUniversité Paris, Paris kHepatinov, Villejuif, France
    AIDS 27:2655-7. 2013
    ..A sustained virological response was achieved after 48 weeks of anti-HCV therapy. Drug-drug interactions between antiretroviral therapy, immunosuppressive agents and anti-HCV therapy could be managed. ..
  13. ncbi request reprint Usefulness of corticosteroids for the treatment of severe and fulminant forms of autoimmune hepatitis
    Philippe Ichai
    Centre Hépatobiliaire and INSERM Unit 785, Assistance Publique Hopitaux de Paris, Universite Paris Sud, Hopital Paul Brousse, Villejuif, France
    Liver Transpl 13:996-1003. 2007
    ..Among the untreated patients, 3 survived after LT and 1 died without LT. In conclusion, corticosteroid therapy is of little benefit in severe and fulminant forms of AIH; it may favor septic complications and should not delay LT...
  14. doi request reprint Long-term follow-up of liver transplanted HIV/hepatitis B virus coinfected patients: perfect control of hepatitis B virus replication and absence of mitochondrial toxicity
    Mariagrazia Tateo
    AP HP Hopital Paul Brousse, Centre Hepato Biliaire, Villejuif, France
    AIDS 23:1069-76. 2009
    ..The outcome of liver transplantation in HBV-HIV-coinfected patients is poorly understood in terms of survival rate, HBV reactivation and mitochondrial toxicity on the liver graft...
  15. doi request reprint Significance of isolated hepatic veno-occlusive disease/sinusoidal obstruction syndrome after liver transplantation
    Mylene Sebagh
    Laboratoire d Anatomie Pathologique, Assistance Publique Hopitaux de Paris, Villejuif, France
    Liver Transpl 17:798-808. 2011
    ..The histological resolution of iVOD/SOS after increase in immunosuppression suggests an immune-mediated origin. Better optimization of immunosuppression may be a curative treatment...
  16. doi request reprint Enfuvirtide: a safe and effective antiretroviral agent for human immunodeficiency virus-infected patients shortly after liver transplantation
    Elina Teicher
    Département Médecine Interne et Infectiologie, AP HP Hopital Paul Brousse, Villejuif, France
    Liver Transpl 15:1336-42. 2009
    ..Moreover, the lack of liver toxicity renders this drug valuable in the event of a severe HCV recurrence...
  17. doi request reprint Twenty-year protocol liver biopsies: Invasive but useful for the management of liver recipients
    Mylene Sebagh
    Laboratoire d Anatomie Pathologique, AP HP Hopital Paul Brousse, Villejuif, France
    J Hepatol 56:840-7. 2012
    ..Most liver transplant centres have discontinued the practice of protocol liver biopsies (LB), mainly because of the perceived lack of therapeutic benefit. This study aimed to examine the usefulness of 20-year LBs...
  18. doi request reprint Histologic findings predictive of a diagnosis of de novo autoimmune hepatitis after liver transplantation in adults
    Mylene Sebagh
    1 Laboratoire d Anatomie Pathologique, AP HP Hopital Paul Brousse, Villejuif, France 2 Division of Transplantation, University of Pittsburgh Medical Center, Pittsburgh, PA 3 Centre Hépato Biliaire, AP HP Hopital Paul Brousse, Villejuif, France 4 Unité Mixte de Recherche 785, Inserm Univ Paris Sud, Villejuif, France 5 Laboratoire d Immunologie Clinique, AP HP Hôpital Saint Antoine, Paris, France 6 Laboratoire de Virologie, AP HP Hopital Paul Brousse, Villejuif, France 7 Address correspondence to Mylène Sebagh, M D, Laboratoire d Anatomie Pathologique, AP HP Hopital Paul Brousse, 14, avenue Paul Vaillant Couturier, 94 804 Villejuif Cedex, France
    Transplantation 96:670-8. 2013
    ..This study aimed to determine which histologic features correlated best with clinical and serologic features of dAIH...
  19. ncbi request reprint Could post-liver transplantation course be helpful for the diagnosis of so called cryptogenic cirrhosis?
    Jean Charles Duclos-Vallée
    Centre Hepato Biliaire, Hopital Paul Brousse, Assistance Publique Hopitaux de Paris, Villejuif, France
    Clin Transplant 19:591-9. 2005
    ..In all cases a precise diagnosis is obviously of practical interest for better management of post-transplant survey and treatment...
  20. ncbi request reprint Liver transplantation for fulminant hepatitis related to nevirapine therapy
    Sophie Buyse
    Department of Hepatology and Hepatobiliar Surgery, Centre Hépato Biliaire and INSERM U785, Hopital Paul Brousse, 12 avenue Paul Vaillant Couturier, 94800, Villejuif, France
    Liver Transpl 12:1880-2. 2006
    ..Non-nucleoside retroviral transcriptase inhibitors are known to cause hepatotoxicity. We describe a detailed case of fulminant hepatitis induced by nevirapine (Viramune) and treated by liver transplantation...
  21. doi request reprint Hepatitis C virus therapy in liver transplant recipients: response predictors, effect on fibrosis progression, and importance of the initial stage of fibrosis
    Bruno Roche
    AP HP Hopital Paul Brousse, Centre Hepato Biliaire, Villejuif, France
    Liver Transpl 14:1766-77. 2008
    ..Fibrosis stage remained stable in patients with SVR and increased in nonresponders. Fibrosis stage > or =3 was associated with a high rate of liver failure, arguing for an early introduction of antiviral therapy...
  22. doi request reprint Escape hepatitis B virus mutations in recipients of antibody to hepatitis B core antigen-positive liver grafts receiving hepatitis B immunoglobulins
    Bruno Roche
    Centre Hepato Biliaire, AP HP Hopital Paul Brousse, Villejuif, France
    Liver Transpl 16:885-94. 2010
    ..The potential benefits of HBIG prophylaxis combined with antiviral drugs require further evaluations. Long-term prophylaxis is needed because of the long interval of de novo HBV infection post-transplant in some patients...
  23. ncbi request reprint Effect of highly active antiretroviral therapy on tacrolimus pharmacokinetics in hepatitis C virus and HIV co-infected liver transplant recipients in the ANRS HC-08 study
    Elina Teicher
    Internal Medicine and Infectious Diseases Department, Hopital Paul Brousse, Assistance Publique Hopitaux de Paris AP HP, Paris, France
    Clin Pharmacokinet 46:941-52. 2007
    ..To characterise the interactions between tacrolimus and antiretroviral drug combinations in hepatitis C virus-HIV co-infected patients who had received a liver transplant...
  24. doi request reprint Resection or transplantation for early hepatocellular carcinoma in a cirrhotic liver: does size define the best oncological strategy?
    Rene Adam
    AP HP Hopital Paul Brousse, Centre Hepato Biliaire, Villejuif, France
    Ann Surg 256:883-91. 2012
    ..Resection and liver transplantation (LT) are the only curative options for hepatocellular carcinoma in cirrhotic patients (HCC-cirr)...
  25. doi request reprint Liver transplantation for hepatocellular carcinoma: the impact of human immunodeficiency virus infection
    Eric Vibert
    Centre Hepato Biliaire, AP HP Hopital Paul Brousse, Villejuif, France
    Hepatology 53:475-82. 2011
    ..08). RFS rates at 1 and 3 years were 69% and 69% in HIV+ patients and 89% and 84% in HIV- patients, respectively (P = 0.09). In univariate analysis, HIV status did not emerge as a prognostic factor for OS or RFS...
  26. doi request reprint Acute hepatitis with periportal confluent necrosis associated with human herpesvirus 6 infection in liver transplant patients
    Sophie Buyse
    AP HP, Hopital Paul Brousse, Centre Hepato Biliaire, Villejuif, France
    Am J Clin Pathol 140:403-9. 2013
    ..To correlate human herpesvirus 6 (HHV-6) viral load with pathologic features in graft acute hepatitis of unknown origin...
  27. ncbi request reprint [Liver transplantation for intrahepatic Rendu-Osler-Weber's disease: the Paul Brousse hospital experience]
    Daniel Azoulay
    Département de Chirurgie Hépato Biliaire, Hopital Paul Brousse, Universite Paris Sud, UPRES 1596, IFR 89 9, Villejuif, France
    Gastroenterol Clin Biol 26:828-34. 2002
    ..Nine centers have reported 15 cases of liver transplantation for Rendu-Osler-Weber's disease with liver involvement. Six cases are reported to analyse the specific technical and hemodynamical aspects...
  28. doi request reprint Are HIV-infected patients candidates for liver transplantation?
    Didier Samuel
    INSERM U785, and Centre Hepato Biliare, AP HP Hopital Paul Brousse, Villejuif, France
    J Hepatol 48:697-707. 2008
  29. doi request reprint A new indication for liver transplantation: nodular regenerative hyperplasia in human immunodeficiency virus-infected patients
    Mariagrazia Tateo
    Centre Hepato Biliaire, AP HP Hopital Paul Brousse, Villejuif, France
    Liver Transpl 14:1194-8. 2008
    ..We describe here our experience concerning 3 HIV-infected patients with severe complications of nodular regenerative hyperplasia treated with liver transplantation...
  30. ncbi request reprint Identification by proteomic tool of atypical anti-liver/kidney microsome autoantibodies targets in de novo autoimmune hepatitis after liver transplantation
    Stéphanie Huguet
    INSERM, Unite 785, Villejuif, F 94804, France
    Ann N Y Acad Sci 1109:345-57. 2007
    ..These results could lead to a better diagnosis of this disease using identified autoantigens in diagnostic tests, and strengthen proteomic approach as a new way of autoantigens investigation...
  31. ncbi request reprint [Liver transplantation for patients infected with both HIV and HCV or HIV and HBV]
    Jean Charles Duclos-Vallée
    Département des Maladies du Foie et INSERM U785, Unité de maladies infectieuses, Universite Paris XI, Centre Hepato Biliaire, Hopital Paul Brousse, 12 14, avenue Paul Vaillant Couturier, 94804, Villejuif, France
    Med Sci (Paris) 23:723-8. 2007
    ..Understanding HCV recurrence mechanisms, and preventing and treating of HCV recurrence are major future challenges...
  32. ncbi request reprint [Treatment of hepatitis C virus associated extrahepatic manifestations]
    Jean Charles Duclos-Vallée
    Département des maladies du foie, Centre Hepato Biliaire, EPI 99 41, Hopital Paul Brousse, 94804 Villejuif
    Gastroenterol Clin Biol 26:B76-81. 2002
  33. doi request reprint Recurrence of autoimmune disease, primary sclerosing cholangitis, primary biliary cirrhosis, and autoimmune hepatitis after liver transplantation
    Jean Charles Duclos-Vallée
    Centre Hepato Biliaire, AP HP Hopital Paul Brousse, Villejuif, France
    Liver Transpl 15:S25-34. 2009
    ..c Immunosuppressive therapy should be pursued even if liver test results are normal...
  34. pmc SPRi-Based Strategy to Identify Specific Biomarkers in Systemic Lupus Erythematosus, Rheumatoid Arthritis and Autoimmune Hepatitis
    Elvire Beleoken
    Research Unit 785, INSERM, Villejuif, France Faculté de Médecine, University Paris Sud, Villejuif, France
    PLoS ONE 8:e84600. 2013
    ..Heterogeneous nuclear ribonucleoprotein (hnRNP) A2/B1 is a target for antinuclear autoantibodies in systemic Lupus erythematosus (SLE), rheumatoid arthritis (RA), and autoimmune hepatitis (AIH)...
  35. doi request reprint Immunoproteomic analysis of potentially severe non-graft-versus-host disease hepatitis after allogenic bone marrow transplantation
    Elvire Beleoken
    INSERM, Unite 785, Villejuif, France
    Hepatology 57:689-99. 2013
    ..Among the 259 spots stained exclusively by sera collected at the time of hepatitis, a total of 240 spots were identified, corresponding to 103 different proteins. Twelve of them were recognized by sera from 3 patients...
  36. ncbi request reprint [Adult to adult living-related liver transplantation. The Paul-Brousse Hospital preliminary experience]
    D Azoulay
    Centre Hepato Biliaire, Hopital Paul Brousse, UPRES 1596, IFR 89 9, Universite Paris Sud, Villejuif, France
    Gastroenterol Clin Biol 25:773-80. 2001
    ..Follow-up ranged from 41 to 157 days (median: 117 days)...
  37. ncbi request reprint [Wilson disease: clinical and biological aspects]
    P Chappuis
    Service de Biochimie et Biologie Moléculaire, Hopital Lariboisiere, AP HP, Paris
    Ann Biol Clin (Paris) 63:457-66. 2005
    ..However, this diagnosis strategy is limited since currently over 320 mutations and 80 polymorphisms have been currently identified...
  38. doi request reprint Management of HCV transplant patients with triple therapy
    Audrey Coilly
    AP HP Hopital Paul Brousse, Centre Hepato Biliaire, Villejuif, France Univ Paris Sud, UMR S 785, Villejuif, France INSERM, Unite 785, Villejuif, France Hepatinov, Villejuif, France
    Liver Int 34:46-52. 2014
    ..We describe the results of triple therapy with boceprevir (BOC) or telaprevir (TVR) for efficacy and safety and comment on future therapeutic strategies in liver transplant recipients. ..
  39. ncbi request reprint [Case report: a series of autoimmune diseases]
    Jean Charles Duclos-Vallée
    Département des Maladies du Foie et Unité INSERM U785, Centre Hepato Biliaire, Hopital Paul Brousse, Villejuif
    Gastroenterol Clin Biol 31:354-6. 2007
  40. ncbi request reprint Liver transplantation in HIV infected patients: indications and results
    Jean Charles Duclos-Vallée
    AP HP Hopital Paul Brousse, Centre Hepato Biliaire, 94800 Villejuif, France
    Acta Gastroenterol Belg 73:380-2. 2010
    ..Long-term outcomes for HBV/HIV are excellent. Outcomes for HCV/HIV coinfected patients are more variable because of potentially severe recurrence on the liver graft. More effective antiviral therapy at an early stage post LT is required...
  41. doi request reprint Safety and efficacy of protease inhibitors to treat hepatitis C after liver transplantation: a multicenter experience
    Audrey Coilly
    AP HP Hopital Paul Brousse, Centre Hepato Biliaire, Villejuif F 94800, France Université Paris Sud, UMR S 785, Villejuif F 94800, France INSERM, Unite 785, Villejuif F 94800, France Hepatinov, Villejuif F 94800, France
    J Hepatol 60:78-86. 2014
    ..Protease inhibitors (PI) with peginterferon/ribavirin have significantly improved SVR rates in HCV G1 patients. Their use to treat HCV recurrence after liver transplantation (LT) is a challenge...
  42. doi request reprint T cells subtypes in a patient with interferon-alpha induced sarcoidosis
    Jean Jacques Monsuez
    AP HP, Hopital Paul Brousse, Department of Internal Medicine, Universite Paris Sud 11, Faculté de Médecine de Bicêtre, Villejuif Cedex, France
    Am J Med Sci 337:60-2. 2009
    ..This activation process also improved over time, but more slowly than clinical symptoms...
  43. ncbi request reprint [Wilson disease]
    Jean Marc Trocello
    Centre national de référence pour la maladie de Wilson, Hopital Lariboisiere, Assistance Publique Hopitaux de Paris, F 75010 Paris, France
    Presse Med 38:1089-98. 2009
    ..Inclusion in the national registry for Wilson Disease must be suggested to all patients. Contact: cmr.wilson@lrb.aphp.fr...
  44. ncbi request reprint Residual hepatitis B virus particles in liver transplant recipients receiving lamivudine: PCR quantitation of HBV DNA and ELISA of preS1 antigen
    M A Petit
    INSERM E99 41 and UPRES 1596, Centre Hepato Biliaire, Villejuif, France
    J Med Virol 65:493-504. 2001
    ..These findings confirm the persistence of HBV in liver transplant recipients despite strong inhibition of replication by lamivudine, and show abnormal viral transcription and/or morphogenesis in lamivudine-resistant patients...