Francois Dubos

Summary

Country: France

Publications

  1. ncbi request reprint [Efficacy and tolerance of mefloquine in the treatment of infants and children with Plasmodium falciparum malaria]
    F Dubos
    Service de Pediatrie, Centre Hospitalier Andrée Rosemon, Clinique de Pediatrie, Hopital Jeanne de Flandre, Lille, France
    Arch Pediatr 10:25-30. 2003
  2. ncbi request reprint [Mefloquine treatment in infants and children with Plasmodium falciparum malaria: an efficient and well tolerated treatment]
    F Dubos
    Service de Réanimation Pédiatrique, Hopital Jeanne de Flandre, 2, Avenue Oscar Lambret, 59037 Lille Cedex, France
    Pathol Biol (Paris) 51:534-9. 2003
  3. ncbi request reprint Safety of mefloquine in infants with acute falciparum malaria
    Francois Dubos
    Pediatric Intensive Care Unit, Jeanne de Flandre Hospital, Lille, France
    Pediatr Infect Dis J 23:679-81. 2004
  4. pmc Decline in pneumococcal meningitis after the introduction of the heptavalent-pneumococcal conjugate vaccine in northern France
    F Dubos
    Paediatric Emergency and Infectious Diseases Unit, Department of Paediatrics, Jeanne de Flandre Hospital and Lille 2 University, Lille, France
    Arch Dis Child 92:1009-12. 2007
  5. ncbi request reprint [Interferon alpha production in the serum of very young infants after viral infections]
    F Dubos
    Service de Pediatrie, Hopital Saint Vincent de Paul, 82, avenue Denfert Rochereau, 75014 Paris, France
    Med Mal Infect 34:561-5. 2004
  6. doi request reprint Distinguishing between bacterial and aseptic meningitis in children: European comparison of two clinical decision rules
    Francois Dubos
    Department of Pediatrics, Saint Vincent de Paul Hospital, 74 82 Avenue Denfert Rochereau, 75014 Paris, France
    Arch Dis Child 95:963-7. 2010
  7. doi request reprint Predicting the risk of severe infection in children with chemotherapy-induced febrile neutropenia
    Francois Dubos
    Univ Lille Nord de France, UDSL, Lille, France
    Curr Opin Hematol 19:39-43. 2012
  8. pmc The value of body weight measurement to assess dehydration in children
    Isabelle Pruvost
    Univ Lille Nord de France, UDSL, Lille, France
    PLoS ONE 8:e55063. 2013
  9. doi request reprint Increased detection rate of Kawasaki disease using new diagnostic algorithm, including early use of echocardiography
    Thérèse Heuclin
    Lille University Hospital, faculté de médecine Henri Warembourg, Lille 2 University, Lille, France
    J Pediatr 155:695-9.e1. 2009
  10. ncbi request reprint Serum procalcitonin and other biologic markers to distinguish between bacterial and aseptic meningitis
    Francois Dubos
    Clinical Epidemiology Unit, Department of Pediatrics, Saint Vincent de Paul Hospital, AP HP, Paris Descartes University, and INSERM U149, Paris, France
    J Pediatr 149:72-6. 2006

Collaborators

Detail Information

Publications31

  1. ncbi request reprint [Efficacy and tolerance of mefloquine in the treatment of infants and children with Plasmodium falciparum malaria]
    F Dubos
    Service de Pediatrie, Centre Hospitalier Andrée Rosemon, Clinique de Pediatrie, Hopital Jeanne de Flandre, Lille, France
    Arch Pediatr 10:25-30. 2003
    ..Only a limited number of treatments are available for use in young children with malaria...
  2. ncbi request reprint [Mefloquine treatment in infants and children with Plasmodium falciparum malaria: an efficient and well tolerated treatment]
    F Dubos
    Service de Réanimation Pédiatrique, Hopital Jeanne de Flandre, 2, Avenue Oscar Lambret, 59037 Lille Cedex, France
    Pathol Biol (Paris) 51:534-9. 2003
    ..The aim of this study was to evaluate the efficacy and tolerance of mefloquine treatment in children, especially in infants of less than 15 kg, in an endemic area of malaria (French Guiana)...
  3. ncbi request reprint Safety of mefloquine in infants with acute falciparum malaria
    Francois Dubos
    Pediatric Intensive Care Unit, Jeanne de Flandre Hospital, Lille, France
    Pediatr Infect Dis J 23:679-81. 2004
    ..Side effects were recorded in 30.8% of patients and consisted chiefly of mild and transient gastrointestinal symptoms. Mefloquine was safe in infants weighing <15 kg in our experience...
  4. pmc Decline in pneumococcal meningitis after the introduction of the heptavalent-pneumococcal conjugate vaccine in northern France
    F Dubos
    Paediatric Emergency and Infectious Diseases Unit, Department of Paediatrics, Jeanne de Flandre Hospital and Lille 2 University, Lille, France
    Arch Dis Child 92:1009-12. 2007
    ..The impact of the heptavalent-pneumococcal conjugate vaccine on the incidence of pneumococcal meningitis in Europe has not yet been assessed...
  5. ncbi request reprint [Interferon alpha production in the serum of very young infants after viral infections]
    F Dubos
    Service de Pediatrie, Hopital Saint Vincent de Paul, 82, avenue Denfert Rochereau, 75014 Paris, France
    Med Mal Infect 34:561-5. 2004
    ..IFN-alpha detection is useful in some clinical circumstances, but its use has never been validated in young infants with viral infections...
  6. doi request reprint Distinguishing between bacterial and aseptic meningitis in children: European comparison of two clinical decision rules
    Francois Dubos
    Department of Pediatrics, Saint Vincent de Paul Hospital, 74 82 Avenue Denfert Rochereau, 75014 Paris, France
    Arch Dis Child 95:963-7. 2010
    ..Clinical decision rules (CDRs) could be helpful to safely distinguish between bacterial and aseptic meningitis (AM)...
  7. doi request reprint Predicting the risk of severe infection in children with chemotherapy-induced febrile neutropenia
    Francois Dubos
    Univ Lille Nord de France, UDSL, Lille, France
    Curr Opin Hematol 19:39-43. 2012
    ..Clinical decision rules (CDRs) have been proposed to help predict the risk of severe infection in children with chemotherapy-induced febrile neutropenia, but none has been fully validated...
  8. pmc The value of body weight measurement to assess dehydration in children
    Isabelle Pruvost
    Univ Lille Nord de France, UDSL, Lille, France
    PLoS ONE 8:e55063. 2013
    ..The performance of dehydration signs or scales determined by using post-illness weight as a gold standard has to be reconsidered...
  9. doi request reprint Increased detection rate of Kawasaki disease using new diagnostic algorithm, including early use of echocardiography
    Thérèse Heuclin
    Lille University Hospital, faculté de médecine Henri Warembourg, Lille 2 University, Lille, France
    J Pediatr 155:695-9.e1. 2009
    ..To determine the incidence of Kawasaki disease (KD) in Northern France by using new American Heart Association (AHA) criteria...
  10. ncbi request reprint Serum procalcitonin and other biologic markers to distinguish between bacterial and aseptic meningitis
    Francois Dubos
    Clinical Epidemiology Unit, Department of Pediatrics, Saint Vincent de Paul Hospital, AP HP, Paris Descartes University, and INSERM U149, Paris, France
    J Pediatr 149:72-6. 2006
    ..To identify the biologic tests that best distinguish between bacterial and aseptic meningitis in an emergency department (ED)...
  11. doi request reprint [Performance of decision rules to predict need for computed tomography among children with blunt head trauma]
    A Martinot
    Service de Pediatrie Generale, urgences et maladies infectieuses, Département de pédiatrie et Pôle Urgence, Hopital Jeanne de Flandre, avenue E Avinee, 59037 Lille Cedex, France
    Arch Pediatr 15:721-3. 2008
  12. doi request reprint [Clinical decision rules in the paediatric emergency department: when and how?]
    M Chalumeau
    Laboratoire d Epidémiologie Clinique, urgences pédiatriques service de pédiatrie générale, Hopital Saint Vincent de Paul, 74, avenue Denfert Rochereau, 75014 Paris, France
    Arch Pediatr 15:718-20. 2008
  13. ncbi request reprint [Procalcitonin bedside testing in the pediatric emergency department]
    M Chalumeau
    Laboratoire d Epidémiologie Clinique, Service de Pediatrie Generale, Universite Paris Descartes, Assistance Publique Hopitaux de Paris, Hopital Saint Vincent de Paul, 74, avenue Denfert Rochereau, 75014 Paris, France
    Arch Pediatr 14:529-31. 2007
  14. pmc Risk of bacterial meningitis in young children with a first seizure in the context of fever: a systematic review and meta-analysis
    Abolfazl Najaf-Zadeh
    Univ Lille Nord de France, UDSL, Lille, France
    PLoS ONE 8:e55270. 2013
    ....
  15. doi request reprint Consensus in diagnostic definitions for bone or joint infections in children by a Delphi method with European French-speaking experts
    Ayoub Mitha
    University Lille Nord de France, Lille, France
    Acta Paediatr 101:e350-6. 2012
    ..Various diagnostic criteria have been proposed for bone or joint infection. This study used a Delphi process to determine the consensual definitions for arthritis, osteomyelitis and bone or joint infections in general in children...
  16. doi request reprint Predicting the risk of severe bacterial infection in children with chemotherapy-induced febrile neutropenia
    Emilie Macher
    Pediatric Hematology Unit, Lille Nord de France University Hospital, Lille, France
    Pediatr Blood Cancer 55:662-7. 2010
    ..The aim of this study was to evaluate the reproducibility of six clinical decision rules proposed in the literature and to compare their performance...
  17. doi request reprint [Distinguishing between bacterial and aseptic meningitis in children in the emergency department]
    F Dubos
    Service des urgences pédiatriques et maladies infectieuses, pôle de l urgence, Hopital Roger Salengro, CHRU Lille, 2, Avenue Oscar Lambret, 59037 Lille Cedex, France
    Arch Pediatr 15:724-5. 2008
  18. ncbi request reprint Infants refusing to walk
    Francois Dubos
    Hopital Jeanne de Flandre, Lille 59037, France
    Lancet 366:93. 2005
  19. doi request reprint Serum procalcitonin level and other biological markers to distinguish between bacterial and aseptic meningitis in children: a European multicenter case cohort study
    Francois Dubos
    Department of Pediatric Emergencies and Infectious Diseases, Roger Salengro Hospital, Centre Hopitalier Universitaire Lille and Lille 2 University, Lille, France
    Arch Pediatr Adolesc Med 162:1157-63. 2008
    ..To validate procalcitonin (PCT) level as the best biological marker to distinguish between bacterial and aseptic meningitis in children in the emergency department...
  20. ncbi request reprint [Evaluation of the antibiotic prescription in a paediatric intensive care unit]
    E Audry-Degardin
    Service de Réanimation Pédiatrique, hôpital Jeanne de Flandre et université de Lille II, avenue E Avinee, 59037 Lille Cedex, France
    Arch Pediatr 14:157-63. 2007
    ..The antibiotic prescription in intensive care units is frequent using often broad-spectrum antibiotics; its quality has never been evaluated in paediatric intensive care units...
  21. ncbi request reprint [Deceptive symptoms and analysis of diagnostic errors in pediatric emergencies]
    A Martinot
    Clinique de pédiatrie et université de Lille II, Hopital Jeanne de Flandre, avenue E Avinee, 59037 Lille Cedex, France
    Arch Pediatr 13:822-4. 2006
  22. ncbi request reprint [Improvement in the management of acute diarrhoea in France?]
    A Martinot
    Pediatrie Generale, urgences et maladies infectieuses, Clinique de pédiatrie et pôle de l urgence, CHRU de Lille, Hopital Jeanne de Flandre, Av E Avinée, 59037 Lille Cedex, France
    Arch Pediatr 14:S181-5. 2007
    ..Isolation and disinfection procedures are insufficient. Rotavirus nosocomial infections incidence is high: 1,6 to 6,3/1000 children less than 5 years of age, contributing to high direct costs...
  23. pmc Epidemiology of hospital admissions for paediatric varicella infections: a one-year prospective survey in the pre-vaccine era
    F Dubos
    Paediatric Emergency Department, Jeanne de Flandre University Hospital, Lille, France
    Epidemiol Infect 135:131-8. 2007
    ..7], complication at admission (aOR 5.8), recurrent fever (aOR 4.5), recent varicella in a sibling (aOR 4.0), and previous physician visit for the same condition (aOR 2.0)...
  24. doi request reprint [Incidence of invasive meningococcal diseases in children in Northern France: usefulness and limits of the discharge code database for correcting compulsory notification data]
    F Dubos
    Service de pédiatrie générale et maladies infectieuses, pôle enfant, Hopital Jeanne de Flandre, CHRU de Lille, avenue E Avinee, 59037 Lille Cedex, France
    Arch Pediatr 16:984-90. 2009
    ..Surveillance of invasive meningococcal diseases (IMD) is based on mandatory reporting. Evaluation of the exhaustivity of the surveillance with capture-recapture analysis can correct for underreporting...
  25. pmc Clinical decision rules to distinguish between bacterial and aseptic meningitis
    F Dubos
    Clinical Epidemiology Unit, Department of Paediatrics, Saint Vincent de Paul Hospital, AP HP, Paris Descartes University, Paris, France
    Arch Dis Child 91:647-50. 2006
    ..Clinical decision rules have been derived to distinguish between bacterial and aseptic meningitis in the emergency room to avoid unnecessary antibiotic treatments and hospitalisations...
  26. ncbi request reprint [Distinction between bacterial and aseptic meningitis in children: refinement of a clinical decision rule]
    F Dubos
    Laboratoire d Epidémiologie Clinique, Service de Pediatrie Generale, Universite Paris Descartes, Hopital Saint Vincent de Paul, Assistance Publique Hopitaux de Paris, France
    Arch Pediatr 14:434-8. 2007
    ....
  27. ncbi request reprint [Assessment of out-patient treatment of varicella in children]
    F Dubos
    Clinique de Pediatrie, Hopital Jeanne de Flandre, CHU Lille
    Presse Med 33:992-6. 2004
    ..Varicella, an almost compulsory affection in children, is complicated in 2% of cases. Some treatments such as powders and non-steroidial anti-inflammatories (NSAIs) may favorise or worsen infectious complications...
  28. ncbi request reprint [Diagnostic tests value at the emergency room: interpretation of results]
    A Martinot
    Pédiatrie générale et urgences, Clinique de Pediatrie, CHU de Lille, Hopital Jeanne de Flandre, avenue E Avinee, 59037 Lille Cedex, France
    Arch Pediatr 12:700-2. 2005
  29. ncbi request reprint [Severity assessment of acute diarrhoea]
    A Martinot
    Clinique de pédiatrie et université de Lille II, Hopital Jeanne de Flandre, avenue E Avinee, 59037 Lille Cedex, France
    Arch Pediatr 13:1466-70. 2006
    ..The presence of at least three signs better correlate with dehydration. Laboratory tests are not helpful. New studies are mandatory to validate severity scoring systems...
  30. ncbi request reprint [Rapid test performance characteristics evaluation]
    A Martinot
    Service de Pediatrie Generale, urgences et maladies infectieuses, Clinique de pédiatrie et pôle de l urgence, CHRU de Lille, Hopital Jeanne de Flandre, avenue E Avinee, 59037 Lille Cedex, France
    Arch Pediatr 14:524-6. 2007
  31. ncbi request reprint [Can clinical epidemiology in emergency care improve acute gastroenteritis management in infants?]
    A Martinot
    Clinique de pédiatrie et université de Lille II, Hopital Jeanne de Flandre, avenue E Avinee, 59037 Lille Cedex, France
    Arch Pediatr 13:555-7. 2006