Keltouma Driouch

Summary

Country: France

Publications

  1. ncbi request reprint Alternative transcripts of the candidate tumor suppressor gene, WWOX, are expressed at high levels in human breast tumors
    Keltouma Driouch
    INSERM E 0017 Oncogénétique, Centre Rene Huguenin, 35 rue Dailly, F 92211 St Cloud, France
    Oncogene 21:1832-40. 2002
  2. ncbi request reprint Gene arrays for diagnosis, prognosis and treatment of breast cancer metastasis
    Keltouma Driouch
    Centre Rene Huguenin, FNCLCC, INSERM U735, Saint Cloud, France
    Clin Exp Metastasis 24:575-85. 2007
  3. doi request reprint A methodological approach to unravel organ-specific breast cancer metastasis
    Sebastien Nola
    Institut Curie, Hôpital René Huguenin, Laboratoire d oncogénétique, 35 rue Dailly, Saint Cloud, France
    J Mammary Gland Biol Neoplasia 17:135-45. 2012
  4. doi request reprint Role of the focal adhesion protein kindlin-1 in breast cancer growth and lung metastasis
    Soraya Sin
    Institut Curie, Laboratoire d oncogénétique, Hôpital René Huguenin, 35 rue Dailly, Saint Cloud, 92210, France
    J Natl Cancer Inst 103:1323-37. 2011
  5. ncbi request reprint Expression of PEA3/E1AF/ETV4, an Ets-related transcription factor, in breast tumors: positive links to MMP2, NRG1 and CGB expression
    Ivan Bieche
    Laboratoire d Oncogénétique INSERM E0017, Centre Rene Huguenin, St Cloud, France
    Carcinogenesis 25:405-11. 2004
  6. doi request reprint Variations in the mRNA expression of poly(ADP-ribose) polymerases, poly(ADP-ribose) glycohydrolase and ADP-ribosylhydrolase 3 in breast tumors and impact on clinical outcome
    Ivan Bieche
    Laboratoire d oncogénétique, Institut Curie Hôpital René Huguenin, 92210, Saint Cloud, France
    Int J Cancer 133:2791-800. 2013
  7. pmc PIK3CA mutation impact on survival in breast cancer patients and in ERα, PR and ERBB2-based subgroups
    Magdalena Cizkova
    Laboratoire d oncogénétique, Institut Curie, Hôpital René Huguenin, 35 rue Dailly, Saint Cloud, F 92210, France
    Breast Cancer Res 14:R28. 2012
  8. doi request reprint A six-gene signature predicting breast cancer lung metastasis
    Thomas Landemaine
    Centre Rene Huguenin, Fédération Nationale des Centres de Lutte Contre le Cancer and Institut National de la Sante et de la Recherche Medicale, U735, Saint Cloud, France
    Cancer Res 68:6092-9. 2008
  9. ncbi request reprint Prognostic value of ERBB family mRNA expression in breast carcinomas
    Ivan Bieche
    Laboratoire d Oncogénétique INSERM E0017, Centre Rene Huguenin, St Cloud, France
    Int J Cancer 106:758-65. 2003
  10. ncbi request reprint Evidence of chromosome regions and gene involvement in inflammatory breast cancer
    Florence Lerebours
    Inserm E0017 oncogénétique, St Cloud, France
    Int J Cancer 102:618-22. 2002

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Alternative transcripts of the candidate tumor suppressor gene, WWOX, are expressed at high levels in human breast tumors
    Keltouma Driouch
    INSERM E 0017 Oncogénétique, Centre Rene Huguenin, 35 rue Dailly, F 92211 St Cloud, France
    Oncogene 21:1832-40. 2002
    ..Furthermore, identification of two distinct alternative WWOX transcripts expressed at high levels in human tumors suggests an involvement of the WWOX gene in breast cancer progression...
  2. ncbi request reprint Gene arrays for diagnosis, prognosis and treatment of breast cancer metastasis
    Keltouma Driouch
    Centre Rene Huguenin, FNCLCC, INSERM U735, Saint Cloud, France
    Clin Exp Metastasis 24:575-85. 2007
    ..Here we review the major studies that had important impacts on the understanding of breast cancer metastasis. We also discuss the future challenges in this research field and the special issues that still need to be examined...
  3. doi request reprint A methodological approach to unravel organ-specific breast cancer metastasis
    Sebastien Nola
    Institut Curie, Hôpital René Huguenin, Laboratoire d oncogénétique, 35 rue Dailly, Saint Cloud, France
    J Mammary Gland Biol Neoplasia 17:135-45. 2012
    ..This methodology can be considered as a useful workflow to identify and validate the genes that trigger and support organ tropism of breast cancer cells during metastasis...
  4. doi request reprint Role of the focal adhesion protein kindlin-1 in breast cancer growth and lung metastasis
    Soraya Sin
    Institut Curie, Laboratoire d oncogénétique, Hôpital René Huguenin, 35 rue Dailly, Saint Cloud, 92210, France
    J Natl Cancer Inst 103:1323-37. 2011
    ..However, the possible role of kindlin-1 in cancer remains unknown...
  5. ncbi request reprint Expression of PEA3/E1AF/ETV4, an Ets-related transcription factor, in breast tumors: positive links to MMP2, NRG1 and CGB expression
    Ivan Bieche
    Laboratoire d Oncogénétique INSERM E0017, Centre Rene Huguenin, St Cloud, France
    Carcinogenesis 25:405-11. 2004
    ..Taken together, the data confirm the role of the PEA3 gene in breast tumorigenesis, and suggest the existence of numerous other still unknown genes transactivated by the PEA3 transcription factor...
  6. doi request reprint Variations in the mRNA expression of poly(ADP-ribose) polymerases, poly(ADP-ribose) glycohydrolase and ADP-ribosylhydrolase 3 in breast tumors and impact on clinical outcome
    Ivan Bieche
    Laboratoire d oncogénétique, Institut Curie Hôpital René Huguenin, 92210, Saint Cloud, France
    Int J Cancer 133:2791-800. 2013
    ..4%). Within the subgroup of triple negative tumors, PARG mRNA levels below the median were associated with a higher risk of developing metastases (p = 0.039) raising the possibility this might be marker of clinical outcome. ..
  7. pmc PIK3CA mutation impact on survival in breast cancer patients and in ERα, PR and ERBB2-based subgroups
    Magdalena Cizkova
    Laboratoire d oncogénétique, Institut Curie, Hôpital René Huguenin, 35 rue Dailly, Saint Cloud, F 92210, France
    Breast Cancer Res 14:R28. 2012
    ..PIK3CA is the oncogene showing the highest frequency of gain-of-function mutations in breast cancer, but the prognostic value of PIK3CA mutation status is controversial...
  8. doi request reprint A six-gene signature predicting breast cancer lung metastasis
    Thomas Landemaine
    Centre Rene Huguenin, Fédération Nationale des Centres de Lutte Contre le Cancer and Institut National de la Sante et de la Recherche Medicale, U735, Saint Cloud, France
    Cancer Res 68:6092-9. 2008
    ..Finally, we show that the signature improves risk stratification independently of known standard clinical variables and a previously established lung metastasis signature based on an experimental breast cancer metastasis model...
  9. ncbi request reprint Prognostic value of ERBB family mRNA expression in breast carcinomas
    Ivan Bieche
    Laboratoire d Oncogénétique INSERM E0017, Centre Rene Huguenin, St Cloud, France
    Int J Cancer 106:758-65. 2003
    ....
  10. ncbi request reprint Evidence of chromosome regions and gene involvement in inflammatory breast cancer
    Florence Lerebours
    Inserm E0017 oncogénétique, St Cloud, France
    Int J Cancer 102:618-22. 2002
    ..In contrast, the DNA amplification levels of ERBB2, MYC and CCND1, as measured by real-time quantitative PCR, did not differ between IBC and non IBC...
  11. pmc Expression analysis of mitotic spindle checkpoint genes in breast carcinoma: role of NDC80/HEC1 in early breast tumorigenicity, and a two-gene signature for aneuploidy
    Ivan Bieche
    INSERM U735, Institut Curie Hôpital René Huguenin, St Cloud, France
    Mol Cancer 10:23. 2011
    ..Alterations of the mitotic spindle checkpoint are likely to contribute to these phenotypes, but little is known about somatic alterations of mitotic spindle checkpoint genes in breast cancer...
  12. ncbi request reprint Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer
    Jeroen T Buijs
    Department of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands
    Cancer Res 67:8742-51. 2007
    ..Because exogenous BMP7 can still counteract the breast cancer growth at the primary site and in bone, BMP7 may represent a novel therapeutic molecule for repression of local and bone metastatic growth of breast cancer...
  13. ncbi request reprint Functional pathways shared by liver and lung metastases: a mitochondrial chaperone machine is up-regulated in soft-tissue breast cancer metastasis
    Rebeca Sanz
    Centre d Oncologia Molecular, Institut de Recerca Oncològica IDIBELL, Hospital Duran i Reynals, Gran Via, S N, Km 2 7, L Hospitalet Ll, 08907, Barcelona, Spain
    Clin Exp Metastasis 24:673-83. 2007
    ....