B Dreno

Summary

Country: France

Publications

  1. ncbi request reprint Standard and new treatments in cutaneous B-cell lymphomas
    Brigitte Dreno
    Department of Dermatology, CHU Hotel Dieu, Nantes, France
    J Cutan Pathol 33:47-51. 2006
  2. ncbi request reprint [General antibiotic therapy in acne]
    Brigitte Dreno
    Clinique dermatologique Centre hospitalier universitaire Hôtel Dieu, 44093 Nantes
    Rev Prat 52:841-3. 2002
  3. ncbi request reprint [Treatment of melanoma]
    Brigitte Dreno
    Unité de cancéro dermatologie, Clinique Dermatologique, CHU Hotel Dieu, Nantes
    Presse Med 32:39-43. 2003
  4. ncbi request reprint [Interferons and malignant melanoma]
    B Dreno
    Service de Dermatologie, Hotel Dieu, Place Alexis Ricordeau, 44093 Nantes, France
    Rev Med Interne 23:489s-493s. 2002
  5. ncbi request reprint Lithium gluconate in the treatment of seborrhoeic dermatitis: a multicenter, randomised, double-blind study versus placebo
    Brigitte Dreno
    CHU Nantes, Clinique Dermatologique, Hotel Dieu, BP 1005, 44035 Nantes Cedex, France
    Eur J Dermatol 12:549-52. 2002
  6. ncbi request reprint [Lithium gluconate 8% in the treatment of seborrheic dermatitis]
    B Dreno
    Departement de Dermatologie, CHU de Nantes, 44035 Nantes Cedex
    Ann Dermatol Venereol 134:347-51. 2007
  7. ncbi request reprint Randomized trial of adoptive transfer of melanoma tumor-infiltrating lymphocytes as adjuvant therapy for stage III melanoma
    Brigitte Dreno
    Skin Cancer Unit, CHR Hotel Dieu, Nantes, 44093 Nantes, France
    Cancer Immunol Immunother 51:539-46. 2002
  8. ncbi request reprint Skin cancers after transplantation
    Brigitte Dreno
    Centre Hospitalier Universitaire, Clinique Dermatologique, Nantes, France
    Nephrol Dial Transplant 18:1052-8. 2003
  9. ncbi request reprint Lithium gluconate 8% vs ketoconazole 2% in the treatment of seborrhoeic dermatitis: a multicentre, randomized study
    B Dreno
    Clinique Dermatologique, CHU Nantes, Hotel Dieu, BP 1005, 44305 Nantes Cedex, France
    Br J Dermatol 148:1230-6. 2003
  10. ncbi request reprint Topical retinaldehyde with glycolic acid: study of tolerance and acceptability in association with anti-acne treatments in 1,709 patients
    B Dreno
    Department of Dermatology, CHU Nantes, Nantes, France
    Dermatology 210:22-9. 2005

Collaborators

Detail Information

Publications107 found, 100 shown here

  1. ncbi request reprint Standard and new treatments in cutaneous B-cell lymphomas
    Brigitte Dreno
    Department of Dermatology, CHU Hotel Dieu, Nantes, France
    J Cutan Pathol 33:47-51. 2006
    ..The aim of this paper is to perform a review of standard and new treatments. Method: This paper provides a literature review of the different treatments of PCBCL...
  2. ncbi request reprint [General antibiotic therapy in acne]
    Brigitte Dreno
    Clinique dermatologique Centre hospitalier universitaire Hôtel Dieu, 44093 Nantes
    Rev Prat 52:841-3. 2002
    ..Resistant strains of Propionibacterium acnes to antibiotics are increasing. Thus, general guidelines are useful when utilizing oral antibiotic therapy in acne...
  3. ncbi request reprint [Treatment of melanoma]
    Brigitte Dreno
    Unité de cancéro dermatologie, Clinique Dermatologique, CHU Hotel Dieu, Nantes
    Presse Med 32:39-43. 2003
    ..Although clinical results are starting to be published, cellular immunotherapy remains in the field of clinical research, within the framework of clinical trials...
  4. ncbi request reprint [Interferons and malignant melanoma]
    B Dreno
    Service de Dermatologie, Hotel Dieu, Place Alexis Ricordeau, 44093 Nantes, France
    Rev Med Interne 23:489s-493s. 2002
    ..Alpha interferon is currently used in the treatment of malignant melanoma mainly as adjuvant therapy at the first stage of the illness (primary tumor) and at the second stage (lymph node invasion)...
  5. ncbi request reprint Lithium gluconate in the treatment of seborrhoeic dermatitis: a multicenter, randomised, double-blind study versus placebo
    Brigitte Dreno
    CHU Nantes, Clinique Dermatologique, Hotel Dieu, BP 1005, 44035 Nantes Cedex, France
    Eur J Dermatol 12:549-52. 2002
    ..3% and 29.1% of the patients in the lithium group, and 5.1% and 3.8% respectively in the placebo group. This study confirms the effectiveness of 8% lithium gluconate ointment in the treatment of seborrhoeic dermatitis...
  6. ncbi request reprint [Lithium gluconate 8% in the treatment of seborrheic dermatitis]
    B Dreno
    Departement de Dermatologie, CHU de Nantes, 44035 Nantes Cedex
    Ann Dermatol Venereol 134:347-51. 2007
    ..Lithioderm 8% gel is applied twice daily over a recommended period of 2 months. It constitutes a new alternative in the treatment of facial seborrheic dermatitis, regardless of severity...
  7. ncbi request reprint Randomized trial of adoptive transfer of melanoma tumor-infiltrating lymphocytes as adjuvant therapy for stage III melanoma
    Brigitte Dreno
    Skin Cancer Unit, CHR Hotel Dieu, Nantes, 44093 Nantes, France
    Cancer Immunol Immunother 51:539-46. 2002
    ....
  8. ncbi request reprint Skin cancers after transplantation
    Brigitte Dreno
    Centre Hospitalier Universitaire, Clinique Dermatologique, Nantes, France
    Nephrol Dial Transplant 18:1052-8. 2003
  9. ncbi request reprint Lithium gluconate 8% vs ketoconazole 2% in the treatment of seborrhoeic dermatitis: a multicentre, randomized study
    B Dreno
    Clinique Dermatologique, CHU Nantes, Hotel Dieu, BP 1005, 44305 Nantes Cedex, France
    Br J Dermatol 148:1230-6. 2003
    ..Objectives This randomized controlled trial was designed to show a non-inferiority of 15% (primary end-point) of lithium gluconate 8% ointment compared with ketoconazole 2% emulsion...
  10. ncbi request reprint Topical retinaldehyde with glycolic acid: study of tolerance and acceptability in association with anti-acne treatments in 1,709 patients
    B Dreno
    Department of Dermatology, CHU Nantes, Nantes, France
    Dermatology 210:22-9. 2005
    ..The aim of this study was to evaluate the tolerance of Diacneal used by 1,709 acne patients in combination with their usual acne products except retinoids...
  11. ncbi request reprint The Cardiff Acne Disability Index: cultural and linguistic validation in French
    Brigitte Dreno
    Department of Dermatology Hôtel Dieu, Nantes, France
    Dermatology 208:104-8. 2004
    ..The Cardiff Acne Disability Index (CADI) evaluates the impact of acne on the patient's life...
  12. ncbi request reprint [Treatment of primary and regional melanoma]
    Brigitte Dreno
    CHRU de Nantes, unité de cancérologie dermatologique, Hotel Dieu, 44093 Nantes 1
    Rev Prat 54:1203-9. 2004
    ..Chemotherapy on the other hand never proved reliable of its effectiveness as adjuvant treatment. In the future, the approaches by vaccination and cellular therapy could be interesting at these stages of the disease...
  13. ncbi request reprint [Clinical and psychological correlation in acne: use of the ECLA and CADI scales]
    B Dreno
    Departement de Dermatologie, CHU Nantes, Hotel Dieu, Nantes, France
    Ann Dermatol Venereol 134:451-5. 2007
    ..The purpose of this study was to use both of these scales in individual applications in order to determine whether or not any correlation exists between the two specific tools and to determine the two groups of patients affected by acne...
  14. ncbi request reprint ECCA grading scale: an original validated acne scar grading scale for clinical practice in dermatology
    B Dreno
    Clinique Dermatologique, CHU, Nantes, France
    Dermatology 214:46-51. 2007
    ..The ECCA grading scale (échelle d'évaluation clinique des cicatrices d'acné) is a tool designed to help dermatologists to assess the severity of acne scars and to standardize the discussions about the treatments of scars...
  15. ncbi request reprint Effect of selenium intake on the prevention of cutaneous epithelial lesions in organ transplant recipients
    B Dreno
    CHU Nantes, Clinique Dermatologique, Hotel Dieu, BP 1005, 44305 Nantes Cedex, France
    Eur J Dermatol 17:140-5. 2007
    ..This was demonstrated by the high rate of epithelial lesions detected, which was more than twice the rate usually reported in the literature...
  16. ncbi request reprint [Epidemiology of melanoma]
    Brigitte Dreno
    Unité de cancéro dermatologie, Clinique Dermatologique, CHU Hotel Dieu, Nantes
    Presse Med 32:30-2. 2003
    ..However, till now, the impact of educational and preventive campaigns with regard to sun exposure, which plays a major role in the development of a melanoma, are still insufficient..
  17. doi request reprint [Orofacial manifestations of systemic sclerosis: A study of 30 consecutive patients]
    C Vincent
    Stomatologie et chirurgie maxillofaciale, Hopital Hotel Dieu, CHU de Nantes, Place Alexis Ricordeau, 44093 Nantes Cedex 01, France
    Rev Stomatol Chir Maxillofac 111:128-34. 2010
    ..The objective of this study was to describe oral and facial manifestations observed in scleroderma patients from our cohort...
  18. ncbi request reprint Multicenter randomized comparative double-blind controlled clinical trial of the safety and efficacy of zinc gluconate versus minocycline hydrochloride in the treatment of inflammatory acne vulgaris
    B Dreno
    Department of Dermatology, CHU Nantes, France
    Dermatology 203:135-40. 2001
    ..CONCLUSION: Minocycline and zinc gluconate are both effective in the treatment of inflammatory acne, but minocycline has a superior effect evaluated to be 17% in our study...
  19. ncbi request reprint Prognostic factors in Sézary syndrome: a study of 28 patients
    P Foulc
    Clinique Dermatologique, CHU Hotel Dieu, 1 Place Alexis Ricordeau, 44000 Nantes, France
    Br J Dermatol 149:1152-8. 2003
    ..5-5 years. Deaths are due in part to the iatrogenic effects of treatments, which suggests that the management of SS could be improved...
  20. doi request reprint A tool to evaluate rapidly the quality of clinical trials on topical acne treatment
    J Revuz
    Service de Dermatologie, Hopital Henri Mondor, Assistance Publique Hopitaux de Paris, Universite Paris XII, Creteil Cedex, France
    J Eur Acad Dermatol Venereol 22:800-6. 2008
    ..Regarding the application of evidence-based medicine in clinical practice, this tool is user friendly and should facilitate the updating of our knowledge...
  21. doi request reprint Development and evaluation of a Global Acne Severity Scale (GEA Scale) suitable for France and Europe
    B Dreno
    Department of Cancero Dermatology, Hotel Dieu, Nantes Cedex, France
    J Eur Acad Dermatol Venereol 25:43-8. 2011
    ..Many acne grading methods exist; however, there is no agreed-upon standard. Our objective was to create and validate a reproducible acne assessment scale for rating the severity of juvenile facial acne suitable for use in France and Europe...
  22. ncbi request reprint [An algorithm for the treatment of acne]
    B Dreno
    Clinique Dermatologique, Nantes
    Ann Dermatol Venereol 130:151-2. 2003
  23. doi request reprint Survey on the management of skin toxicity associated with EGFR inhibitors amongst French physicians
    L Peuvrel
    Department of Dermato Cancerology CHU de Nantes, Nantes, France
    J Eur Acad Dermatol Venereol 27:419-29. 2013
    ..However, they are frequently associated with cutaneous side-effects, which can hamper compliance, lead to treatment refusal and impair quality of life...
  24. doi request reprint Management of cutaneous adverse events induced by anti-EGFR (epidermal growth factor receptor): a French interdisciplinary therapeutic algorithm
    Z Reguiai
    Department of Dermatology, CHU Reims, Hopital Robert Debre, avenue du Général Koenig, 51092 Reims, France
    Support Care Cancer 20:1395-404. 2012
    ..Cutaneous adverse events induced by epidermal growth factor receptor (EGFR) inhibitors can hamper the patients' quality of life. The aim of our work was to draft an algorithm for the optimised management of this skin toxicity...
  25. doi request reprint Bacterial resistance in French acne patients
    G Dumont-Wallon
    CHU Nantes, Clinique Dermatologique, Hotel Dieu, Nantes Cedex, France
    Int J Dermatol 49:283-8. 2010
    ..Numerous series of cases have been published on European populations of acne patients, but at the moment we still have very few data regarding France...
  26. ncbi request reprint Heredity: a prognostic factor for acne
    F Ballanger
    Department of Dermatology, Hotel Dieu, FR 44035 Nantes, France
    Dermatology 212:145-9. 2006
    ..The role of heredity in acne severity and therapeutic response remains unclear...
  27. doi request reprint Addition of zinc and manganese to a biological dressing
    I Tenaud
    UTCG, CHU Nantes, Institut de Biologie, Nantes Cedex, France
    J Dermatolog Treat 20:90-3. 2009
    ..In addition, at the clinical level, a dressing of keratinocytes suspended in a fibrin glue has been proposed for the treatment of chronic wounds...
  28. ncbi request reprint Evaluation of a 1-h exposure time to mechlorethamine in patients undergoing topical treatment
    P Foulc
    Department of Dermatology, CHU Nantes, 1 Place Alexis Ricordeau, 44035 Nantes cedex 1, France
    Br J Dermatol 147:926-30. 2002
    ..Reducing the concentration to avoid this side-effect has been only modestly successful...
  29. doi request reprint Interest of the association retinaldehyde/glycolic acid in adult acne
    B Dreno
    Department of Dermatology, CHU Nantes, France
    J Eur Acad Dermatol Venereol 23:529-32. 2009
    ..The aim of this study was to evaluate the tolerance and the efficiency of RAL (0.1%)/GA (6%) in adult women with acne when used alone or in combination with their usual acne products except retinoids...
  30. doi request reprint The advantage of establishing homogeneous patient groups: is it worth isolating 'juvenile acne of the face'?
    J Revuz
    Service de Dermatologie, Hopital Henri Mondor, Assistance Publique Hopitaux de Paris, Universite Paris XII, Creteil, France
    J Eur Acad Dermatol Venereol 22:1429-34. 2008
    ..Homogeneous patient groups must therefore be created before measuring the severity of acne and interpreting the results of therapeutic trials. The individualization of 'juvenile acne of the face' is a first step in this direction...
  31. ncbi request reprint [Dacarbazine: deticene]
    G Quereux
    Service de Dermatologie, Hotel Dieu, 1, Place Alexis Ricordeau, 44093 Nantes Cedex 1
    Ann Dermatol Venereol 134:1001-3. 2007
  32. ncbi request reprint Pathogenetic mechanisms of vitiligo in a patient with Sézary syndrome
    A C Knol
    INSERM U601, CHU Hotel Dieu, 9 quai Moncousu, 44093 Nantes Cedex 01, France
    Br J Dermatol 153:1207-12. 2005
    ..The role of interferon in the induction of this T-lymphocyte subpopulation is discussed...
  33. doi request reprint Is primary melanoma ulceration a factor of good response to adoptive immunotherapy?
    L Peuvrel
    Nantes University Hospital Centre, Skin Cancer Unit, Alexis Ricordeau CIC biothérapie, INSERM 0305, Nantes, France
    J Eur Acad Dermatol Venereol 25:1311-7. 2011
    ..However, two recent studies suggest that it could be a predictive factor of good response to a non-specific immunotherapy (interferon-alpha) and to an active immunotherapy (vaccine)...
  34. ncbi request reprint An epidemiological study of acne in female adults: results of a survey conducted in France
    F Poli
    Hĵpital Henri Mondor, Service de Dermatologie, Creteil, France
    J Eur Acad Dermatol Venereol 15:541-5. 2001
    ..For most patients, acne did not severely impair their quality of life. CONCLUSION: This study shows a prevalence of acne in 41% of women in the general population. A high proportion of these acne cases are late onset acne...
  35. ncbi request reprint [Treatment of seborrheic dermatitis]
    G Quereux
    Clinique Dermatologique, Hotel Dieu, 1, Place Alexis Ricordeau, 44093 Nantes
    Ann Dermatol Venereol 131:130-4. 2004
  36. ncbi request reprint Prospective study of risk factors of relapse after treatment of acne with oral isotretinoin
    G Quereux
    Department of Dermatology, Hotel Dieu, Nantes University Hospital, Place Alexis Recordeau, FR 44035 Nantes Cedex 1, France
    Dermatology 212:168-76. 2006
    ..The effectiveness of oral isotretinoin against acne is undeniable. However, few data on the maintenance of effect after treatment termination have been published...
  37. doi request reprint [Lymphomatoid granulomatosis revealed by cutaneous lesions]
    G Quereux
    Clinique Dermatologique, CHU de Nantes, 1, Place A Ricordeau, 44093 Nantes Cedex 01, France
    Ann Dermatol Venereol 138:591-6. 2011
    ..It most frequently involves the lungs, skin and central nervous system and arises preferentially in patients with immune disorders. Here we report a case revealed by cutaneous lesions in an immunocompetent patient...
  38. doi request reprint Evolution of clinical and molecular responses to bexarotene treatment in cutaneous T-cell lymphoma
    F Ballanger
    Department of Cancer Dermatology, INSERM U892, University Hospital Hotel Dieu, Place Alexis Ricordeau, Nantes, France
    Dermatology 220:370-5. 2010
    ..The mechanisms of action of bexarotene are not well understood...
  39. ncbi request reprint Prognostic value of tyrosinase reverse-transcriptase polymerase chain reaction in metastatic melanoma
    G Quereux
    Department of Dermatology, CHU, Nantes, France
    Dermatology 203:221-5. 2001
    ..CONCLUSION: The prognostic value of this method could be improved by combining it with PCR of other melanoma markers (Melan A, Mage 3) or assays of serum markers (S 100 protein or lactate dehydrogenase)...
  40. ncbi request reprint Erythromycin-resistance of cutaneous bacterial flora in acne
    B Dreno
    Department of Dermatology, CHU Nantes, Hotel Dieu, Pl A Ricordeau, 44093 Nantes Cedex 1, France
    Eur J Dermatol 11:549-53. 2001
    ..However, zinc combined with erythromycin in vitro did not modify the erythromycin MIC. This first French study on bacterial resistance to erythromycin in acne patients confirms the results of studies performed in other countries...
  41. doi request reprint Melanoma and rituximab: an incidental association?
    L Peuvrel
    Department of Dermato Cancerology, Nantes University Hospital, INSERM U892 CNRS U6299, CIC biothérapie INSERM 0503, Nantes, France
    Dermatology 226:274-8. 2013
    ..In case of individual melanoma history, the benefit/risk ratio of initiating rituximab therapy should be carefully assessed. © 2013 S. Karger AG, Basel. ..
  42. doi request reprint Onychopathy induced by temsirolimus, a mammalian target of rapamycin inhibitor
    L Peuvrel
    Department of Dermatology Cancerology, Nantes University Hospital, and CIC biothérapie INSERM 0305, Nantes, France
    Dermatology 224:204-8. 2012
    ..We review the cutaneous and mucosal toxicities induced by temsirolimus and everolimus, two mTOR inhibitors used as anticancer agents and by their parent molecule sirolimus...
  43. ncbi request reprint Induction of toll-like receptors by Propionibacterium acnes
    S Jugeau
    INSERM U601, CHU, Pl A Ricordeau, 44095 Nantes, France
    Br J Dermatol 153:1105-13. 2005
    ..Recent studies have found that keratinocytes express toll-like receptors (TLRs) implicated in immediate immunity. No studies have, to date, been carried out on the action of P. acnes upon TLR activation in keratinocytes...
  44. doi request reprint Innate immunity: a crucial target for zinc in the treatment of inflammatory dermatosis
    A Brocard
    Skin Cancer Unit, Nantes University Hospital, Nantes, France
    J Eur Acad Dermatol Venereol 25:1146-52. 2011
    ..It has been shown by different data that it could play a crucial role not only in the regulation of adaptative immunity but also in innate immunity which plays a crucial role in skin...
  45. doi request reprint Expert opinion: efficacy of superficial chemical peels in active acne management--what can we learn from the literature today? Evidence-based recommendations
    B Dreno
    Unit of Skin Oncology, University Hospital Center, Nantes, France
    J Eur Acad Dermatol Venereol 25:695-704. 2011
    ..Superficial chemical peels offer therapeutic results in a convenient, affordable treatment. Many clinicians use these peels in the treatment of acne and acne-prone oily skin...
  46. ncbi request reprint [Autoimmunity induced by low doses of interferon in melanoma stage I]
    F Ballanger
    Clinique Dermatologique, Hotel Dieu, Nantes
    Ann Dermatol Venereol 133:543-8. 2006
    ..The secondary objective consisted to seek the existence or not of a correlation with the clinical relapse, to determine the prevalence of appearance of clinical signs of autoimmune diseases and dysthyroidie...
  47. doi request reprint [Acne, pregnant women and zinc salts: a literature review]
    B Dreno
    Clinique Dermatologique, Hotel Dieu, CHU de Nantes, Place Alexis Ricordeau, 44035 Nantes, France
    Ann Dermatol Venereol 135:27-33. 2008
    ....
  48. ncbi request reprint Combined 0.1% retinaldehyde/ 6% glycolic acid cream in prophylaxis and treatment of acne scarring
    Brigitte Dreno
    A Sygros Hospital, University of Athens, Athens, Greece
    Dermatology 214:260-7. 2007
    ..Acne often results in permanent, badly tolerated, difficult to treat scars...
  49. ncbi request reprint Acne: evolution of the clinical practice and therapeutic management of acne between 1996 and 2000
    Brigitte Dreno
    Acne Research and Study Group GREA, Dermatology Department, Nantes University Hospital Center, Place Alexis Ricordeau, France
    Eur J Dermatol 13:166-70. 2003
    ..The profile of acne patients evolved slightly between 1996 and 2000 and interestingly the treatments were modified to take into account the information in the literature such as bacterial resistance or severe side effects...
  50. doi request reprint Management of skin ageing: how to combine cosmetic procedures
    Brigitte Dreno
    Unité de Cancérologie Cutanée, Hotel Dieu, Place Alexis Ricordeau, Nantes Cedex 01, France
    Eur J Dermatol 18:444-51. 2008
    ..This therapeutic strategy is based both on an analysis of the literature and the personal experience of the experts...
  51. ncbi request reprint Topical antibacterial therapy for acne vulgaris
    Brigitte Dreno
    Department of Dermatology, Hotel Dieu, Nantes, France
    Drugs 64:2389-97. 2004
    ..Topical and oral antibacterials should not be used in combination for the treatment of acne vulgaris, since this association may increase the risk of bacterial resistance...
  52. ncbi request reprint Effect of zinc gluconate on propionibacterium acnes resistance to erythromycin in patients with inflammatory acne: in vitro and in vivo study
    Brigitte Dreno
    Department of Dermatology, CHU Nantes, 44035 Nantes Cedex 01, France
    Eur J Dermatol 15:152-5. 2005
    ..Thus, association of zinc salts via a systemic route and topical erythromycin treatment seems an interesting option in the light of an increasing number of patients carrying erythromycin resistant Propionibacterium acnes strains...
  53. ncbi request reprint Loss of oncostatin M receptor beta in metastatic melanoma cells
    A Lacreusette
    INSERM, U601, Groupe de Recherche Cytokines et Récepteurs, Institut de Biologie, Nantes, France
    Oncogene 26:881-92. 2007
    ..Altogether, our results suggest a role for OSM in the prevention of melanoma progression and that metastatic melanoma cells could escape this growth control by the epigenetic silencing of OSMRbeta...
  54. doi request reprint Efficacy and safety of biologics in erythrodermic psoriasis: a multicentre, retrospective study
    M Viguier
    Sorbonne Paris Cité Université Paris Diderot, Assistance Publique Hopitaux de Paris, Service de Dermatologie, Hopital Saint Louis, 1 avenue Claude Vellefaux, 75475 Paris Cedex 10, France
    Br J Dermatol 167:417-23. 2012
    ..Even though efficacy of biologics has been extensively studied in psoriasis vulgaris, studies in erythrodermic psoriasis, the most severe form of the disease, have been scarcely reported...
  55. doi request reprint Algorithm for dermocosmetic use in the management of cutaneous side-effects associated with targeted therapy in oncology
    B Dreno
    Department of Cancero Dermatology, Hotel Dieu, CHU Nantes, France
    J Eur Acad Dermatol Venereol 27:1071-80. 2013
    ..Due to the current lack of clinical evidence, only a review of published recommendations including suggestions for concomitant cosmetic use was conducted. ..
  56. ncbi request reprint Modulatory effects of selenium and strontium salts on keratinocyte-derived inflammatory cytokines
    P Celerier
    Department of Dermatology, University Hospital, Nantes, France
    Eur J Dermatol 12:LVI-LVIII. 2002
  57. doi request reprint Semiology of skin toxicity associated with epidermal growth factor receptor (EGFR) inhibitors
    L Peuvrel
    Department of Dermato Cancerology, Nantes University Hospital CIC biotherapy INSERM 0305, 1 place Ricordeau, 44000, Nantes, France
    Support Care Cancer 20:909-21. 2012
    ..Non-specialists can have difficulty in recognising this unusual skin toxicity...
  58. doi request reprint Combination therapy with adapalene-benzoyl peroxide and oral lymecycline in the treatment of moderate to severe acne vulgaris: a multicentre, randomized, double-blind controlled study
    B Dreno
    Hopital Hotel Dieu, Department of Dermato Oncology, Place Alexis Ricordeau, 44093 Nantes Cedex 1, France
    Br J Dermatol 165:383-90. 2011
    ..Oral antibiotics in association with a topical retinoid with or without benzoyl peroxide (BPO) are the recommended first-line option in the treatment of moderate to severe acne vulgaris...
  59. ncbi request reprint Clinical variants of the preprotuberant stage of dermatofibrosarcoma protuberans
    L Martin
    Department of Dermatology, Hôpital Porte Madeleine, CHR Orleans, 45032 Orleans Cedex 1, France
    Br J Dermatol 153:932-6. 2005
    ..Some cases of dermatofibrosarcoma protuberans (DFSP) do not protrude above the skin...
  60. doi request reprint Melanoma gene expression and clinical course
    M Vourc'h-Jourdain
    Unit of Skin Cancer Nantes University Hospital, Nantes, France
    Arch Dermatol Res 301:673-9. 2009
    ..However, with regard to certain sub-groups, such as stage III samples, tumour gene expression was significantly associated with survival...
  61. doi request reprint Impact of a campaign to train general practitioners in screening for melanoma
    Lucie Peuvrel
    Réseau Mélanome Ouest, Dermatological Clinic, Nantes University Hospital Center, Nantes, France
    Eur J Cancer Prev 18:225-9. 2009
    ..As a result, after a short prior training, the ABCDE rule clearly seems to be a valuable tool. Dermatologists retain an important role both in the diagnostic confirmation of melanomas and in the training of general practitioners...
  62. doi request reprint Female acne - a different subtype of teenager acne?
    S Preneau
    CHU de Nantes, Skin Cancer Unit, and CIC biothérapie, INSERM, Nantes, France
    J Eur Acad Dermatol Venereol 26:277-82. 2012
    ..Specific global assessment and therapeutic algorithm would be necessary for female acne, which in addition, in future would have to be considered separately from teenagers for the evaluation of a new drug...
  63. doi request reprint Adjuvant prophylactic regional radiotherapy versus observation in stage I Merkel cell carcinoma: a multicentric prospective randomized study
    T Jouary
    Skin Cancer Unit, Dermatology Department, Hôpital Saint André, Bordeaux, France
    Ann Oncol 23:1074-80. 2012
    ..No randomized study has ever been conducted in MCC. The purpose of this study was to assess the efficacy and safety of prophylactic adjuvant radiotherapy on the regional nodes...
  64. doi request reprint [Recent data on epidemiology of acne]
    B Dreno
    Clinique Dermatologique, CHU Hotel Dieu, Place Alexis Ricordeau, 44093 Nantes Cedex 01, France
    Ann Dermatol Venereol 137:S49-51. 2010
    ..Actually, acne is regarded today as a chronic disease requiring treatment of induction and maintenance...
  65. ncbi request reprint Human papillomavirus and extragenital in situ carcinoma
    G Quereux
    Department of Dermatology, Hotel Dieu, CHU, Nantes, France
    Dermatology 209:40-5. 2004
    ..The relation between human papillomavirus (HPV) and extragenital Bowen's disease (BD) is controversial...
  66. pmc Comparison of three culture media for the establishment of melanoma cell lines
    M C Pandolfino
    Unit of Cell and Gene Therapy UTCG, Nantes University Hospital CHU de Nantes, 44093, Nantes, France
    Cytotechnology 62:403-12. 2010
    ..Furthermore the cells obtained could be used as multiple antigenic sources in active or adoptive immunotherapy protocols...
  67. ncbi request reprint [Viruses involved in allograft recipients'cutaneous carcinomas]
    E Parant
    Clinique Dermatologique, , Place Alexis Ricordeau, 44093 Nantes
    Ann Dermatol Venereol 128:871-5. 2001
    ..Moreover, for the first time, cytomegalovirus DNA was detected in carcinomas of renal allograft recipients with a higher frequency in the patients with multiple carcinomas...
  68. doi request reprint Temozolomide associated with PEG-interferon in patients with metastatic melanoma: a multicenter prospective phase I/II study
    Bernard Guillot
    Department of Dermatology, Hopital Saint Eloi, University of Montpellier I, Montpellier, France
    Melanoma Res 18:141-6. 2008
    ..At a lower level, this treatment was effective and deserves further investigations to define its indications in metastatic melanoma patients...
  69. doi request reprint Routine bone marrow biopsy in the initial evaluation of primary cutaneous B-cell lymphoma does not appear justified
    Gaelle Quereux
    Dermatology Department, Nantes University Hospital Center, Place Alexis Ricordeau, 44093 Nantes, France
    Eur J Dermatol 19:216-20. 2009
    ..In conclusion, this study demonstrates that it is not indispensable to perform a routine BMB for a Primary cutaneous B-cell lymphoma with cutaneous lesions on examination and with negative CT Scan and blood laboratory evaluations...
  70. doi request reprint [Survey of post-graduate training for dermatology and venereology residents in France (2005-2010)]
    J Plee
    Service de Dermatologie, Hopital Robert Debre, CHU de Reims, avenue du Maréchal Koenig, 51092 Reims Cedex, France
    Ann Dermatol Venereol 140:259-65. 2013
    ..Training procedures for dermatology residents have never been evaluated in French university hospitals. The present study describes the methods used over the last 5 years...
  71. doi request reprint [Infliximab-induced hepatitis during treatment of vulvar Crohn's disease]
    S Causse
    Service de Dermatologie, CHU de Nantes, 3, Place Alexis Ricordeau, 44000 Nantes, France
    Ann Dermatol Venereol 140:46-51. 2013
    ..We report a case of acute cytolytic hepatitis induced by infliximab in a patient with severe vulvar Crohn's disease...
  72. doi request reprint [Orofacial manifestations of systemic sclerosis: a study of 30 consecutive patients]
    C Vincent
    Stomatologie et chirurgie maxillofaciale, Hopital Hotel Dieu, CHU de Nantes, Place Alexis Ricordeau, 44093 Nantes Cedex 01, France
    Rev Med Interne 30:5-11. 2009
    ..The objective of this study was to describe oral and facial manifestations observed in scleroderma patients from our cohort...
  73. doi request reprint [Paraneoplastic multicentric reticulohistiocytosis]
    C Nicol
    Clinique Dermatologique, CHU de Nantes, Place Alexis Ricordeau, Nantes Cedex 01, France
    Ann Dermatol Venereol 138:405-8. 2011
    ..Herein, we report the case of a female patient in whom HM enabled us to diagnose gastric carcinoma...
  74. doi request reprint [Anatomy, immunology of skin and cutaneous annexes]
    B Dreno
    CHU de Nantes, Clinique Dermatologique, Place Alexis Ricordeau, Nantes Cedex I, France
    Ann Dermatol Venereol 135:S149-52. 2008
    ....
  75. doi request reprint [Anatomy and physiology of skin and cutaneous annexes]
    B Dreno
    CHU de Nantes, Clinique Dermatologique, Place Alexis Ricordeau, Nantes Cedex 1, France
    Ann Dermatol Venereol 136:S247-51. 2009
    ....
  76. doi request reprint [A therapeutic algorithm in acne: why?]
    B Dreno
    Clinique Dermatologique, CHU Hotel Dieu, Place Alexis Ricordeau, 44093 Nantes Cedex 01, France
    Ann Dermatol Venereol 137:S66-8. 2010
    ....
  77. ncbi request reprint [Passive immunotherapy of melanoma]
    Francine Jotereau
    INSERM U463, Institut de Biologie, CHR, 9, quai Moncousu, 44093 Nantes, France
    Bull Cancer 90:583-6. 2003
    ..Although all the questions about optimal methods for this mode of therapy are not solved, these recent results constitute a major breakthrough in the field of the tumor immunotherapy...
  78. ncbi request reprint Acne: physical treatment
    Brigitte Dreno
    Department of Dermatology, Nantes, France
    Clin Dermatol 22:429-33. 2004
    ..Different physical treatments may be used in acne therapy. The main indications are for treating retentional lesions (open and comedones), inflamed lesions, and scars...
  79. doi request reprint Treatment of metastatic melanoma with autologous Melan-A/MART-1-specific cytotoxic T lymphocyte clones
    Amir Khammari
    Skin Cancer Unit, Nantes CHU, Nantes, cedex 01 44093, France
    J Invest Dermatol 129:2835-42. 2009
    ..Thus, over the course of an adoptive cell transfer, monitoring this melanoma-specific T-cell expansion in patient blood appears crucial for predicting the clinical efficiency of such an immunological approach...
  80. ncbi request reprint Diagnosis of primary cutaneous B-cell lymphoma by immunohistochemical and in situ hybridization methods
    Stephanie Mendes
    Department of Dermatology, University Hospital of Nantes, France
    Acta Derm Venereol 83:167-70. 2003
    ..It is concluded that kappa or lambda chain in situ hybridization is an interesting complementary technique to detect monoclonal B cells, if the immunohistochemical technique is negative...
  81. ncbi request reprint Tissue prognostic markers for adoptive immunotherapy in melanoma
    Gaelle Quereux
    Unit of Skin Oncology, CHU, Place A Ricordeau, 44035 Nantes, France
    Eur J Dermatol 17:295-301. 2007
    ..This work suggests that a weak expression of immunosuppressive cytokines (IL-10, TGF-beta and alpha-MSH) could be a favourable prognostic marker for patients receiving autologous TIL...
  82. doi request reprint Prospective multicenter study of pegylated liposomal doxorubicin treatment in patients with advanced or refractory mycosis fungoides or Sézary syndrome
    Gaelle Quereux
    Departments of Dermatology, Centre Hospitalier Universitaire, Nantes, France
    Arch Dermatol 144:727-33. 2008
    ..To assess the rate of objective response to pegylated liposomal doxorubicin hydrochloride (Caelyx) in patients with advanced or refractory cutaneous T-cell lymphoma (CTCL)...
  83. ncbi request reprint Gluten intolerance and skin diseases
    Philippe Humbert
    Department of Dermatology, University of Franche Comte, CHU Saint Jacques, 25030 Besancon, France
    Eur J Dermatol 16:4-11. 2006
    ..Intestinal biopsy is usually needed to establish the diagnosis of CD or GI. Thus, gluten intolerance gives rise to a variety of dermatological manifestations which may benefit from a gluten-free diet...
  84. pmc alpha v beta3-dependent cross-presentation of matrix metalloproteinase-2 by melanoma cells gives rise to a new tumor antigen
    Emmanuelle Godefroy
    Institut National de la Sante et de la Recherche Medicale, Unite 601, Nantes, France
    J Exp Med 202:61-72. 2005
    ..Because MMP-2 activity is critical for melanoma progression, the MMP-2 peptide should be cross-presented by most progressing melanomas and represents a unique antigen for vaccine therapy of these tumors...
  85. ncbi request reprint In vitro modulation of TLR-2, CD1d and IL-10 by adapalene on normal human skin and acne inflammatory lesions
    Isabelle Tenaud
    Department of Dermatology, CHU, Nantes, France
    Exp Dermatol 16:500-6. 2007
    ..The decreased expression of TLR-2 by the keratinocytes can contribute to explain the anti-inflammatory activity of adapalene observed in clinical practice...
  86. doi request reprint Frequent occurrence of high affinity T cells against MELOE-1 makes this antigen an attractive target for melanoma immunotherapy
    Yann Godet
    UMR INSERM U892, CRCNA, Nantes, France
    Eur J Immunol 40:1786-94. 2010
    ..This study documents the existence of a large TCR repertoire specific for the MELOE-1/A2 epitope and its capacity to give rise to antitumor CTL that supports the development of immunotherapies targeting this epitope...
  87. ncbi request reprint Epidemiology of acne
    Brigitte Dreno
    Department of Dermatology, Hospital Hotel Dieu, Nantes, France
    Dermatology 206:7-10. 2003
  88. ncbi request reprint Identification of five new HLA-B*3501-restricted epitopes derived from common melanoma-associated antigens, spontaneously recognized by tumor-infiltrating lymphocytes
    Houssem Benlalam
    Unit Institut National de la Santé et de la Recherche Médicale Unité 463, Nantes, France
    J Immunol 171:6283-9. 2003
    ..These data have important implications for the formulation of polypeptide-based vaccines as well as for the monitoring of melanoma-specific CTL response in HLA-B*3501 melanoma patients...
  89. ncbi request reprint Modulation in vitro of keratinocyte integrins by interferon-alpha and interferon-gamma
    Isabelle Tenaud
    Laboratory of Immuno Dermatology, INSERM U463, Nantes, France
    Int J Dermatol 41:836-40. 2002
    ..In the same way, integrins are adhesion molecules which regulate keratinocyte proliferation and differentiation...
  90. ncbi request reprint Adoptive transfer of tumor-reactive Melan-A-specific CTL clones in melanoma patients is followed by increased frequencies of additional Melan-A-specific T cells
    Virginie Vignard
    Unit Institut National de la Santé et de la Recherche Médicale INSERM Unité 601, Nantes, France
    J Immunol 175:4797-805. 2005
    ..Together, our results suggest that infused CTL clones may have initiated an antitumor response that may have resulted in the expansion of a Melan-A-specific CTL repertoire...
  91. doi request reprint Infantile acne: a retrospective study of 16 cases
    Muriel Hello
    Department of Dermatology, Nantes University Hospital, Nantes, France
    Pediatr Dermatol 25:434-8. 2008
    ..On the basis of the frequency of scarring, and the severity and average duration of lesions, the use of oral retinoids in severe infantile acne warrants evaluation...
  92. ncbi request reprint CD8(+) T lymphocytes reactive against Epstein-Barr virus antigens in skin lesions of a patient with Sézary syndrome
    Anne Chantal Knol
    Institut National de la Sante et de la Recherche Medicale, Nantes, France
    J Am Acad Dermatol 53:897-900. 2005
    ..This is, to our knowledge, the first description of the presence of EBV-specific T lymphocytes among tumor-infiltrating lymphocytes infiltrating the lesional skin of a patient with Sézary syndrome...
  93. pmc MELOE-1 is a new antigen overexpressed in melanomas and involved in adoptive T cell transfer efficiency
    Yann Godet
    Institut National de Santé et de Recherche Médicale, Unité Mixte de Recherche 892, 44093 Nantes, France
    J Exp Med 205:2673-82. 2008
    ..Overall, our results suggest that this new antigen is involved in immunosurveillance and, thus, represents an attractive target for immunotherapy protocols of melanoma...
  94. doi request reprint A comparison of two regimens of topical corticosteroids in the treatment of patients with bullous pemphigoid: a multicenter randomized study
    Pascal Joly
    Department of Dermatology, INSERM U901, University of Rouen, Rouen, France
    J Invest Dermatol 129:1681-7. 2009
    ..54; 95% confidence interval, 0.30-0.97; P=0.039). This mild regimen allows a 70% reduction of the cumulative doses of CS and improves BP patients' outcome...
  95. ncbi request reprint Clinical experience: practical management of five patients with cutaneous T-cell lymphoma (CTCL)-related symptoms
    Reinhard Dummer
    Department of Dermatology, University Hospital of Zurich, Switzerland
    Semin Oncol 33:S26-32. 2006
    ..This article provides details of five real-life case studies to illustrate how cutaneous T-cell lymphoma management can be tailored to the needs of each individual patient...
  96. ncbi request reprint A comparison of oral and topical corticosteroids in patients with bullous pemphigoid
    Pascal Joly
    Department of Dermatology and Biostatistics, INSERM Unite 519, University of Rouen, Rouen, France
    N Engl J Med 346:321-7. 2002
    ..Because elderly people have low tolerance for standard regimens of oral corticosteroids, we studied whether highly potent topical corticosteroids could decrease mortality while controlling disease...
  97. ncbi request reprint Immunotherapy of metastatic melanoma by intratumoral injections of Vero cells producing human IL-2: phase II randomized study comparing two dose levels
    Christoph Rochlitz
    Departement Innere Medizin, Abteilung für Onkologie, Kantonsspital, Petersgraben 4, CH 4031 Basel, Switzerland
    Cancer Gene Ther 9:289-95. 2002
    ..The objectives of this study were to evaluate the tolerance and incidence of tumor regression in patients with metastatic melanoma, following repeated administration of Vero-IL-2 cells...
  98. ncbi request reprint Interstitial brachytherapy of periorificial skin carcinomas of the face: a retrospective study of 97 cases
    Emmanuel Rio
    Department of Radiotherapy, CRLCC Nantes Atlantique, Saint Herblain, France
    Int J Radiat Oncol Biol Phys 63:753-7. 2005
    ..To analyze outcomes after interstitial brachytherapy of facial periorificial skin carcinomas...
  99. ncbi request reprint Management of acne: a report from a Global Alliance to Improve Outcomes in Acne
    Harald Gollnick
    American Academy of Dermatology, Inc
    J Am Acad Dermatol 49:S1-37. 2003
  100. ncbi request reprint Infusion of Melan-A/Mart-1 specific tumor-infiltrating lymphocytes enhanced relapse-free survival of melanoma patients
    Houssem Benlalam
    INSERM U601, 9 quai Moncousu, 44093, Nantes Cedex 1, France
    Cancer Immunol Immunother 56:515-26. 2007
    ..These results further support the relevance of Melan-A/MART-1 antigen as a prime target for immunotherapy protocols in melanoma...
  101. ncbi request reprint [Clinical practice guideline: 2005 update of recommendations for the management of patients with cutaneous melanoma without distant metastases (summary report)]
    Sylvie Negrier
    Centre Leon Berard, Lyon
    Bull Cancer 93:371-84. 2006
    ..This work is based on the methodology developed in the "Standards, Options and Recommendations" (SOR) project...