M Dougados

Summary

Country: France

Publications

  1. ncbi Monitoring osteoarthritis progression and therapy
    Maxime Dougados
    Université René Descarte and Hôpital Cochin, Paris, France
    Osteoarthritis Cartilage 12:S55-60. 2004
  2. ncbi Reproducibility and sensitivity to change of various methods to measure joint space width in osteoarthritis of the hip: a double reading of three different radiographic views taken with a three-year interval
    Emmanuel Maheu
    Service de Rhumatologie, Hopital Saint Antoine, Paris, France
    Arthritis Res Ther 7:R1375-85. 2005
  3. ncbi Clinical relevance of C-reactive protein in axial involvement of ankylosing spondylitis
    M Dougados
    Université René Descartes and Hôpital Cochin, Paris, France
    J Rheumatol 26:971-4. 1999
  4. ncbi When a DMARD fails, should patients switch to sulfasalazine or add sulfasalazine to continuing leflunomide?
    M Dougados
    Hopital Cochin, Rene Descartes University, 27, rue du Faubourg Saint Jacques, 75679 Paris Cedex 14, France
    Ann Rheum Dis 64:44-51. 2005
  5. ncbi Long term structural effects of combination therapy in patients with early rheumatoid arthritis: five year follow up of a prospective double blind controlled study
    J F Maillefert
    Centre Hospitalier Universitaire Dijon, and INSERM ERIT M 0207, University of Burgundy, Dijon, France
    Ann Rheum Dis 62:764-6. 2003
  6. ncbi Conventional treatments for ankylosing spondylitis
    M Dougados
    Department of Rheumatology, Rene Descartes University, Hopital Cochin, 27 rue du Faobourg Saint Jacques, F 75014 Paris, France
    Ann Rheum Dis 61:iii40-50. 2002
  7. ncbi EULAR standardised operating procedures for the elaboration, evaluation, dissemination, and implementation of recommendations endorsed by the EULAR standing committees
    M Dougados
    Clinique de Rhumatologie B Groupe, Hospitalier Cochin, Paris, France
    Ann Rheum Dis 63:1172-6. 2004
  8. ncbi Why is the concept of spondyloarthropathies important?
    Maxime Dougados
    Department of Rheumatology B, Rene Descartes University, Cochin Hospital, 27 rue du Faubourg Saint Jacques, 75014, Paris, France
    Best Pract Res Clin Rheumatol 16:495-505. 2002
  9. ncbi The use of glucosamine therapy in osteoarthritis
    Djamila Zerkak
    Rheumatology B Department, Rene Descartes University, AP HP Cochin Hospital, 27 rue du Faubourg Saint Jacques, Paris 75014, France
    Curr Pain Headache Rep 8:507-11. 2004
  10. ncbi Disease activity measures for rheumatoid arthritis
    M Dougados
    Hopital Cochin, Descartes University, Service de Rhumatologie B, Paris, France
    Clin Exp Rheumatol 25:S22-9. 2007

Collaborators

Detail Information

Publications164 found, 100 shown here

  1. ncbi Monitoring osteoarthritis progression and therapy
    Maxime Dougados
    Université René Descarte and Hôpital Cochin, Paris, France
    Osteoarthritis Cartilage 12:S55-60. 2004
    ..The requirement for total hip arthroplasty has been evaluated as a composite outcome measure for trials of hip OA and found to be valid, simple, and clinically pertinent...
  2. ncbi Reproducibility and sensitivity to change of various methods to measure joint space width in osteoarthritis of the hip: a double reading of three different radiographic views taken with a three-year interval
    Emmanuel Maheu
    Service de Rhumatologie, Hopital Saint Antoine, Paris, France
    Arthritis Res Ther 7:R1375-85. 2005
    ..6 or greater for assessing JSN over three years. Selecting a single reader was the most accurate method, with 0.3 mm precision. Using this cutoff, 50% of patients were classified as 'progressors'...
  3. ncbi Clinical relevance of C-reactive protein in axial involvement of ankylosing spondylitis
    M Dougados
    Université René Descartes and Hôpital Cochin, Paris, France
    J Rheumatol 26:971-4. 1999
    ..This outcome measure does not seem to be of great interest in the short term evaluation of fast acting drugs. However, the longterm clinical significance of such an increase in CRP remains to be investigated...
  4. ncbi When a DMARD fails, should patients switch to sulfasalazine or add sulfasalazine to continuing leflunomide?
    M Dougados
    Hopital Cochin, Rene Descartes University, 27, rue du Faubourg Saint Jacques, 75679 Paris Cedex 14, France
    Ann Rheum Dis 64:44-51. 2005
    ..To evaluate the efficacy and safety of adding sulfasalazine to leflunomide treatment compared with switching to sulfasalazine alone in patients with RA with an inadequate response to leflunomide monotherapy...
  5. ncbi Long term structural effects of combination therapy in patients with early rheumatoid arthritis: five year follow up of a prospective double blind controlled study
    J F Maillefert
    Centre Hospitalier Universitaire Dijon, and INSERM ERIT M 0207, University of Burgundy, Dijon, France
    Ann Rheum Dis 62:764-6. 2003
    ....
  6. ncbi Conventional treatments for ankylosing spondylitis
    M Dougados
    Department of Rheumatology, Rene Descartes University, Hopital Cochin, 27 rue du Faobourg Saint Jacques, F 75014 Paris, France
    Ann Rheum Dis 61:iii40-50. 2002
    ..Thus, for patients with AS, the future of successful treatment lies in the development of pharmacological agents capable of both altering the disease course through intervention at sites of disease pathogenesis, and controlling symptoms...
  7. ncbi EULAR standardised operating procedures for the elaboration, evaluation, dissemination, and implementation of recommendations endorsed by the EULAR standing committees
    M Dougados
    Clinique de Rhumatologie B Groupe, Hospitalier Cochin, Paris, France
    Ann Rheum Dis 63:1172-6. 2004
  8. ncbi Why is the concept of spondyloarthropathies important?
    Maxime Dougados
    Department of Rheumatology B, Rene Descartes University, Cochin Hospital, 27 rue du Faubourg Saint Jacques, 75014, Paris, France
    Best Pract Res Clin Rheumatol 16:495-505. 2002
    ..for research purposes but also in daily practice because such recognition has at least a threefold effect: (a) it permits earlier diagnosis, (b) it facilitates patients' education and monitoring, and (c) it has prognostic implications..
  9. ncbi The use of glucosamine therapy in osteoarthritis
    Djamila Zerkak
    Rheumatology B Department, Rene Descartes University, AP HP Cochin Hospital, 27 rue du Faubourg Saint Jacques, Paris 75014, France
    Curr Pain Headache Rep 8:507-11. 2004
    ..An ongoing long-term clinical trial in the US will possibly permit to investigate the clinical relevance of these results and give appropriate recommendations...
  10. ncbi Disease activity measures for rheumatoid arthritis
    M Dougados
    Hopital Cochin, Descartes University, Service de Rhumatologie B, Paris, France
    Clin Exp Rheumatol 25:S22-9. 2007
    ..Further studies are required to better evaluate the clinical relevance of methods for assessing disease activity in patients with RA...
  11. ncbi Evaluation of disease activity assessments in patients with rheumatoid arthritis and an inadequate response to anti-TNF therapy: analyses of abatacept clinical trial data
    M Dougados
    Rene Descartes University, Medicine Faculty, Hospital Cochin, Rheumatology B Department, Paris, France
    Clin Exp Rheumatol 28:258-60. 2010
    ....
  12. ncbi Evaluation of different methods used to assess disease activity in rheumatoid arthritis: analyses of abatacept clinical trial data
    M Dougados
    Rene Descartes University, Medicine Faculty, UPRES EA 4058, APHP, Cochin Hospital, Rheumatology B Department, Paris, France
    Ann Rheum Dis 68:484-9. 2009
    ....
  13. ncbi Treatment of spondyloarthropathies. Recent advances and prospects in 2001
    M Dougados
    Universite Rene Descartes, Department of Rheumatology B, Hopital Cochin, Paris, France
    Joint Bone Spine 68:557-63. 2001
    ..Importantly, maintenance treatment seems effective not only on peripheral joint manifestations but also on axial manifestations that fail to respond to NSAIDs. Thalidomide and TNF antagonists are promising maintenance agents...
  14. ncbi How can one develop disease-modifying drugs in osteoarthritis?
    Maxime Dougados
    Rene Descartes University, Cochin Hospital, 27 rue du Faubourg, Saint Jacques, 75014 Paris, France
    Curr Rheumatol Rep 7:22-8. 2005
    ....
  15. ncbi Outcome measures for clinical trials of disease modifying osteoarthritis drugs in patients with hip osteoarthritis
    Maxime Dougados
    Service de Rhumatologie, , 27 Rue du Faubourg St-Jacques, Paris 75014, France
    J Rheumatol Suppl 70:66-9. 2004
  16. ncbi Evaluation of the structure-modifying effects of diacerein in hip osteoarthritis: ECHODIAH, a three-year, placebo-controlled trial. Evaluation of the Chondromodulating Effect of Diacerein in OA of the Hip
    M Dougados
    Université René Descartes and Hôpital Cochin, Service de Rhumatologie B, Paris, France
    Arthritis Rheum 44:2539-47. 2001
    ..To evaluate the ability of diacerein, an interleukin-1beta inhibitor, to slow the progressive decrease in joint space width observed in patients with hip osteoarthritis (OA)...
  17. ncbi The role of anti-inflammatory drugs in the treatment of osteoarthritis: a European viewpoint
    M Dougados
    Rene Descartes University, Cochin Hospital, Rheumatology B Department, 27 rue de Faubourg Saint Jacques, 75014 Paris, France
    Clin Exp Rheumatol 19:S9-14. 2001
    ..However, two questions remain: the choice of NSAIDs versus analysis as first line therapy for symptomatic treatment in OA, and the long-term structural effect of such therapy...
  18. ncbi EULAR report on the use of ultrasonography in painful knee osteoarthritis. Part 1: prevalence of inflammation in osteoarthritis
    P Conaghan
    Rheumatology Department, Cochin Hospital, Paris, France
    Ann Rheum Dis 64:1703-9. 2005
    ..77 for joint effusion). CONCLUSION: US can detect synovial inflammation and effusion in painful knee OA, which correlate significantly with knee synovitis, effusion, and clinical parameters suggestive of an inflammatory "flare"...
  19. ncbi Finalisation and validation of the rheumatoid arthritis impact of disease score, a patient-derived composite measure of impact of rheumatoid arthritis: a EULAR initiative
    L Gossec
    Paris Descartes University, Medicine Facility, APHP, Rheumatology B Department, Cochin Hospital, Paris, France
    Ann Rheum Dis 70:935-42. 2011
    ..The objectives were to finalise the RAID and examine its psychometric properties...
  20. ncbi Laterally elevated wedged insoles in the treatment of medial knee osteoarthritis: a prospective randomized controlled study
    J F Maillefert
    Cochin Hospital, Rheumatology B, , Paris, France
    Osteoarthritis Cartilage 9:738-45. 2001
    ..However, the decrease in NSAIDs consumption together with better compliance in the treated group are in favor of a beneficial effect of laterally-wedged insoles in medial femoro-tibial OA...
  21. ncbi Efficacy of tumour necrosis factor blockers in reducing uveitis flares in patients with spondylarthropathy: a retrospective study
    S Guignard
    Rene Descartes University, Medicine Faculty, APHP, Cochin Hospital, Rheumatology B Department, Paris, France
    Ann Rheum Dis 65:1631-4. 2006
    ..To evaluate the efficacy of anti-tumour necrosis factor (TNF) treatments (given for rheumatological manifestations) in reducing uveitis flares in patients with spondylarthropathy in daily practice...
  22. ncbi Clinical and ultrasonographic predictors of joint replacement for knee osteoarthritis: results from a large, 3-year, prospective EULAR study
    P G Conaghan
    Paris Descartes University, Medicine Faculty, UPRES EA 4058 and APHP, Rheumatology B Department, Cochin Hospital, 27 rue du Faubourg St Jacques, Paris, France
    Ann Rheum Dis 69:644-7. 2010
    ..To determine clinical and ultrasonographic predictors of joint replacement surgery across Europe in primary osteoarthritis (OA) of the knee...
  23. ncbi [Spondyloarthropathy: MR imaging features]
    A Feydy
    Service de Radiologie B, Universite Paris Descartes, Hopital Cochin, AP HP, Paris, France
    J Radiol 91:1057-67. 2010
    ..MRI frequently allows early diagnosis of inflammatory lesions in patients with normal plain films. In addition, MRI is useful for the detection and quantification of inflammatory and structural lesions, and to assess disease activity...
  24. ncbi Continuation of treatment with infliximab in ankylosing spondylitis: 2-yr open follow-up
    L Gossec
    Rheumatologie B, Hopital Cochin, 27 rue du Fbg St Jacques, 75014 Paris, France
    Rheumatology (Oxford) 45:859-62. 2006
    ..To evaluate the continuation and safety of treatment with infliximab in ankylosing spondylitis (AS) over a 2-yr period...
  25. ncbi Comparative evaluation of three semi-quantitative radiographic grading techniques for knee osteoarthritis in terms of validity and reproducibility in 1759 X-rays: report of the OARSI-OMERACT task force
    L Gossec
    Paris Descartes University, Medicine Faculty, UPRES EA 4058, Paris, France
    Osteoarthritis Cartilage 16:742-8. 2008
    ..The objective of this work was to compare the measurement properties of three categorical X-ray scoring methods of knee osteoarthritis (OA), both on semiflexed and extended views...
  26. ncbi Prognostic factors for remission in early rheumatoid arthritis: a multiparameter prospective study
    L Gossec
    , Cochin Hospital, Department of Rheumatology B, Paris, France
    Ann Rheum Dis 63:675-80. 2004
    ..CONCLUSIONS: Baseline prognostic factors for remission in early rheumatoid arthritis were mainly clinical markers of disease activity and radiological scores...
  27. ncbi Complication rates of 127 surgical procedures performed in rheumatic patients receiving tumor necrosis factor alpha blockers
    A Ruyssen Witrand
    Paris Rene Descartes University, Medicine Faculty, AP HP, Cochin Hospital, Rheumatology B Department, Paris, France
    Clin Exp Rheumatol 25:430-6. 2007
    ..The aim of this study was to assess the complication rate after surgery in such patients, to assess the effect of interrupting TNF blocker therapy, and to identify other potential predictors of complications...
  28. ncbi Relevant change in radiological progression in patients with hip osteoarthritis. II. Determination using an expert opinion approach
    J F Maillefert
    , Cochin Hospital, Institut de Rhumatologie, Paris, France
    Rheumatology (Oxford) 41:148-52. 2002
    ..7 respectively. CONCLUSION: This study suggests that a change of at least 0.4 mm in the radiological JSW could be considered clinically relevant. Other studies using other sets of patients and other methods are needed for validation...
  29. ncbi Synovitis: a potential predictive factor of structural progression of medial tibiofemoral knee osteoarthritis -- results of a 1 year longitudinal arthroscopic study in 422 patients
    X Ayral
    Service de Rhumatologie B, Hopital Cochin, AP HP, Universite Rene Descartes, Paris, France
    Osteoarthritis Cartilage 13:361-7. 2005
    ..To evaluate the prevalence of synovitis in painful medial tibiofemoral knee osteoarthritis (OA) and to evaluate correlation between synovitis and the structural severity and progression of tibiofemoral cartilage damage...
  30. ncbi [MR Imaging of the spine and sacroiliac joints in ankylosing spondylitis]
    A Feydy
    Universite Paris Descartes, Hopital Cochin, AP HP, Paris, France
    J Radiol 91:140-50. 2010
    ..Moreover, MRI is useful for the detection and quantification of inflammatory and structural lesions, and to assess disease activity...
  31. ncbi Paracetamol in osteoarthritis of the knee
    C Miceli-Richard
    Cochin Hospital, AP-HP, , Paris, France
    Ann Rheum Dis 63:923-30. 2004
    ..The tolerability and safety of paracetamol, at the recommended maximum dose of 4 g/day, was confirmed over 6 weeks...
  32. ncbi Sex differences in hip osteoarthritis: results of a longitudinal study in 508 patients
    J F Maillefert
    Institut de Rhumatologie, , Cochin Hospital, Paris, France
    Ann Rheum Dis 62:931-4. 2003
    ..CONCLUSION: Hip OA in women is more frequently part of a polyarticular OA, and displays greater symptomatic and structural severity...
  33. ncbi Minimum clinically important improvement and patient acceptable symptom state in pain and function in rheumatoid arthritis, ankylosing spondylitis, chronic back pain, hand osteoarthritis, and hip and knee osteoarthritis: Results from a prospective multina
    F Tubach
    INSERM, Universite Paris Diderot, and AP HP, Hopital Bichat, Paris, France
    Arthritis Care Res (Hoboken) 64:1699-707. 2012
    ..To estimate the minimum clinically important improvement (MCII) and patient acceptable symptom state (PASS) values for 4 generic outcomes in 5 rheumatic diseases and 7 countries...
  34. ncbi Comparison of the clinical characteristics of vasculitis occurring during anti-tumor necrosis factor treatment or not in rheumatoid arthritis patients. A systematic review of 2707 patients, 18 vasculitis
    S Guignard
    Universite Rene Descartes, Faculte de Medecine, AP HP, Hopital Cochin, Service de Rhumatologie B, Paris, France
    Clin Exp Rheumatol 26:S23-9. 2008
    ..Comparison of vasculitis occurring in rheumatoid arthritis (RA) patients undergoing anti-tumor necrosis factor (TNF) treatment and those not...
  35. ncbi Disease activity score-driven therapy versus routine care in patients with recent-onset active rheumatoid arthritis: data from the GUEPARD trial and ESPOIR cohort
    M Soubrier
    Department of Rheumatology, Hopital G Montpied, 63003 Clermont Ferrand, France
    Ann Rheum Dis 70:611-5. 2011
    ....
  36. ncbi The role of pain and functional impairment in the decision to recommend total joint replacement in hip and knee osteoarthritis: an international cross-sectional study of 1909 patients. Report of the OARSI-OMERACT Task Force on total joint replacement
    L Gossec
    Paris Descartes University, Medicine Faculty, APHP, Rheumatology B Department, Cochin Hospital, Paris, France
    Osteoarthritis Cartilage 19:147-54. 2011
    ..To assess the pain and functional disability levels corresponding to an indication for total joint replacement (TJR) in hip and knee osteoarthritis (OA)...
  37. ncbi Predictive factors of total hip replacement due to primary osteoarthritis: a prospective 2 year study of 505 patients
    L Gossec
    Service de Rhumatologie B, Hopital Cochin, 27, rue du Faubourg Saint Jacques, 75014 Paris, France
    Ann Rheum Dis 64:1028-32. 2005
    ..To determine the 2 year total hip replacement (THR) rate and to identify factors predictive of THR due to primary osteoarthritis (OA)...
  38. ncbi Efficacy of cyclo-oxygenase-2 inhibition by etoricoxib and naproxen on the axial manifestations of ankylosing spondylitis in the presence of peripheral arthritis
    L Gossec
    Hopital Cochin, Rhumatologie B, Paris, France
    Ann Rheum Dis 64:1563-7. 2005
    ..The combined efficacy of selective and non-selective cyclo-oxygenase-2 (COX-2) inhibition on the axial manifestations of ankylosing spondylitis (AS) in the presence or absence of chronic peripheral arthritis was evaluated...
  39. ncbi Cost effectiveness of two therapeutic regimens of infliximab in ankylosing spondylitis: economic evaluation within a randomised controlled trial
    B Fautrel
    APHP, Groupe Hospitalier Pitie Salpetriere, Service of Rhumatologie, Paris, France
    Ann Rheum Dis 69:424-7. 2010
    ..To determine the incremental cost-effectiveness ratios (ICERs) of two therapeutic regimens of infliximab for ankylosing spondylitis (AS)...
  40. ncbi Leflunomide in rheumatoid arthritis in daily practice: treatment discontinuation rates in comparison with other DMARDs
    I Bettembourg-Brault
    Rheumatology B Department, Cochin Hospital, AP-HP, Rene Descartes University, Paris, France
    Clin Exp Rheumatol 24:168-71. 2006
    ..CONCLUSION: This study conducted in conditions of daily practice when leflunomide was first available suggests a higher discontinuation rate of leflunomide because of adverse events when compared to other DMARDs...
  41. ncbi Management of osteoarthritis (OA) with an unsupervised home based exercise programme and/or patient administered assessment tools. A cluster randomised controlled trial with a 2x2 factorial design
    P Ravaud
    , , , , Paris et INSERM U444, Paris, France
    Ann Rheum Dis 63:703-8. 2004
    ....
  42. ncbi Recurrence of spondylarthropathy among first-degree relatives of patients: a systematic cross-sectional study
    E Dernis
    Rheumatology Division, Cochin Hospital, Assistance Publique des Hopitaux de Paris, Paris, France
    Ann Rheum Dis 68:502-7. 2009
    ..To examine the recurrence of manifestations belonging to the spectrum of spondylarthropathy (SpA) in first-degree relatives of patients with SpA, and to estimate the recurrence risk ratio...
  43. ncbi Body weight, body composition, and bone turnover changes in patients with spondyloarthropathy receiving anti-tumour necrosis factor {alpha} treatment
    K Briot
    Hopital Cochin, Departement de Rhumatologie, 27 rue du Faubourg St Jacques, 75014 Paris, France
    Ann Rheum Dis 64:1137-40. 2005
    ..To determine the changes in body weight, body composition, and bone turnover in patients with spondyloarthropathy (SpA) treated with anti-tumour necrosis factor alpha (TNFalpha)...
  44. ncbi EULAR report on the use of ultrasonography in painful knee osteoarthritis. Part 2: exploring decision rules for clinical utility
    P Conaghan
    Rheumatology Department, Cochin Hospital, 27, rue du Faubourg St Jacques, 75014 Paris, France
    Ann Rheum Dis 64:1710-4. 2005
    ..Thus sensitive imaging techniques such as US remain the most useful tool for demonstrating synovial inflammation of the knee at the individual level...
  45. ncbi Risk of serious infections during rituximab, abatacept and anakinra treatments for rheumatoid arthritis: meta-analyses of randomised placebo-controlled trials
    C Salliot
    Rene Descartes University, Medicine Faculty, AP HP, Cochin Hospital, Rheumatology B Department, Paris, France
    Ann Rheum Dis 68:25-32. 2009
    ..Recently, new biological agents have become available. Their safety is an important issue...
  46. ncbi Relevant change in radiological progression in patients with hip osteoarthritis. I. Determination using predictive validity for total hip arthroplasty
    J F Maillefert
    , Cochin Hospital, Institut de Rhumatologie, Paris, France
    Rheumatology (Oxford) 41:142-7. 2002
    ..For validation, similar studies should be conducted in other countries with different health-care systems...
  47. ncbi Increase in bone mineral density of patients with spondyloarthropathy treated with anti-tumour necrosis factor alpha
    F Allali
    Rheumatology Department, , Cochin Hospital, Paris, France
    Ann Rheum Dis 62:347-9. 2003
    ..35, p=0.06). CONCLUSION: These data suggest that a benefit of anti-tumour necrosis factor alpha therapy on BMD in patients with SpA may be through an uncoupling effect on bone cells...
  48. ncbi Tolerance and short term efficacy of rituximab in 43 patients with systemic autoimmune diseases
    J-E Gottenberg
    Service de Rhumatologie, , , , France
    Ann Rheum Dis 64:913-20. 2005
    ..This study showed good tolerance and short term clinical efficacy, with marked corticosteroid reduction in patients with SLE, pSS, vasculitis, and polymyositis...
  49. ncbi Anticitrullinated protein/peptide antibody assays in early rheumatoid arthritis for predicting five year radiographic damage
    O Meyer
    Service de Rhumatologie, CHU Bichat, AP HP, Paris, France
    Ann Rheum Dis 62:120-6. 2003
    ..To study the value of antibodies to citrullinated proteins/peptides for predicting joint outcomes in patients with recent onset rheumatoid arthritis (RA)...
  50. ncbi Reporting of patient-reported outcomes in recent trials in rheumatoid arthritis: a systematic literature review
    U Kalyoncu
    Paris Descartes University, Medicine Faculty, Paris, France
    Ann Rheum Dis 68:183-90. 2009
    ..The objective of this study was to assess the frequency of use of different PROs in recently published RA articles and to compare the tools used through a systemic literature review...
  51. ncbi Individualising the Western Ontario and McMaster Universities osteoarthritis index (WOMAC) function subscale: incorporating patient priorities for improvement to measure functional impairment in hip or knee osteoarthritis
    R Seror
    AP HP, Hopital Bichat, Département d Epidémiologie, Biostatistique et Recherche Clinique, INSERM, U738, Paris, France
    Ann Rheum Dis 67:494-9. 2008
    ....
  52. ncbi Changes in bone density in patients with ankylosing spondylitis: a two-year follow-up study
    J F Maillefert
    Department of Rheumatology, Dijon University Hospital, France
    Osteoporos Int 12:605-9. 2001
    ..1% +/- 5.7 and -1.2% +/- 3.9 in patients with and without persistent inflammation; respectively; p = 0.007). These results suggest that persistent inflammation might be an etiologic factor of bone loss in AS...
  53. ncbi Combination therapy in early rheumatoid arthritis
    L Gossec
    , Cochin Hospital, Paris, France
    Clin Exp Rheumatol 21:S174-8. 2003
    ..It appears likely that the place of combination therapy will increase in the coming decades, even in very early RA patients, where the ultimate goal is persistent remission...
  54. ncbi Comparative evaluation of three semi-quantitative radiographic grading techniques for hip osteoarthritis in terms of validity and reproducibility in 1404 radiographs: report of the OARSI-OMERACT Task Force
    L Gossec
    Paris Descartes University, Medicine Faculty, UPRES EA 4058, APHP, Rheumatology B Department, Cochin Hospital, Paris, France
    Osteoarthritis Cartilage 17:182-7. 2009
    ..The objective of this work was to compare the measurement properties of three categorical X-ray scoring methods for hip osteoarthritis (OA)...
  55. ncbi Glucocorticoid sparing effect of tumour necrosis factor alpha inhibitors in rheumatoid arthritis in real life practice
    R Seror
    Paris Descartes University, Cochin Hospital, France
    Clin Exp Rheumatol 27:807-13. 2009
    ..To determine, in real life practice, the impact of anti-tumour necrosis factor (TNF)-alpha on glucocorticoid (GC) use in rheumatoid arthritis (RA) patients...
  56. ncbi Assessment of progression in knee osteoarthritis: results of a 1 year study comparing arthroscopy and MRI
    E Pessis
    Department of Radiology B, Hopital Cochin 27, AP HP, Universite Paris V, rue du Faubourg Saint Jacques, 75679 Paris Cedex 14, France
    Osteoarthritis Cartilage 11:361-9. 2003
    ....
  57. ncbi Influence of flare design on symptomatic efficacy of non-steroidal anti-inflammatory drugs in osteoarthritis: a meta-analysis of randomized placebo-controlled trials
    S Trijau
    Paris Descartes University, Medicine Faculty, UPRES EA 4058, France
    Osteoarthritis Cartilage 18:1012-8. 2010
    ..e., including only patients with an increase in their pain after stopping their usual treatment (NSAIDs or analgesic)...
  58. ncbi Efficacy of celecoxib, a cyclooxygenase 2-specific inhibitor, in the treatment of ankylosing spondylitis: a six-week controlled study with comparison against placebo and against a conventional nonsteroidal antiinflammatory drug
    M Dougados
    , Cochin Hospital, Paris, France
    Arthritis Rheum 44:180-5. 2001
    ..CONCLUSION: The results of this study confirm the clinically relevant antiinflammatory effect of celecoxib at a 200-mg daily dosage, with significant improvement of both pain and function in patients with AS...
  59. ncbi [US evaluation of the hands and feet in rheumatoid arthritis]
    H Guerini
    Service de Radiologie B, Hopital Cochin, 75014 Paris, France
    J Radiol 91:99-110. 2010
    ..In this article, we will describe this protocol used daily in our institution for early diagnosis and therapeutic management of this disease...
  60. ncbi Factors associated with severe skin infections in patients treated with biologic therapies for inflammatory rheumatic diseases
    E Régnier-Rosencher
    Department of Dermatology, Hopital Cochin, APHP, Universite Rene Descartes Paris V, Paris, France
    Dermatology 224:72-83. 2012
    ..The incidence of severe infections is increased under biologic therapies and the skin is the second localization...
  61. ncbi European League Against Rheumatism recommendations for the management of psoriatic arthritis with pharmacological therapies
    L Gossec
    Paris Descartes University, Paris, France
    Ann Rheum Dis 71:4-12. 2012
    ..The authors present European League Against Rheumatism (EULAR) recommendations for the treatment of PsA with systemic or local (non-topical) symptomatic and disease-modifying antirheumatic drugs (DMARD)...
  62. ncbi DNA microarray allows molecular profiling of rheumatoid arthritis and identification of pathophysiological targets
    V Devauchelle
    Institut Cochin, Paris, France
    Genes Immun 5:597-608. 2004
    ..It is proposed that such an approach allows valuable diagnosis/prognostics tools in RA to be established and potential targets for combating the disease to be identified...
  63. ncbi Tumour necrosis factor-alpha blockers in rheumatoid arthritis: review of the clinical experience
    C Richard-Miceli
    Clinique de Rhumatologie, , , , 27 rue du Fauborg Saint-Jacques, 75679 Paris Cedex 14, France
    BioDrugs 15:251-9. 2001
    ..This therapeutic response seems to be unequalled by "conventional" treatments in rheumatoid arthritis, and is incontestably a turning point in the therapeutic management of this disease...
  64. ncbi An international study on starting tumour necrosis factor-blocking agents in ankylosing spondylitis
    T Pham
    Department of Rheumatology, Aix Marseille II University, Conception Hospital, 147 Bd Baille, 13005 Marseille, France
    Ann Rheum Dis 65:1620-5. 2006
    ....
  65. ncbi Ultrasonic backscatter and transmission parameters at the os calcis in postmenopausal osteoporosis
    C Roux
    , Hĵpital Cochin, , Paris, France
    J Bone Miner Res 16:1353-62. 2001
    ..However, BUB evaluation, which does not require two transducers and may be implemented in conventional reflection mode systems, warrants further studies...
  66. ncbi Infections during tumour necrosis factor-alpha blocker therapy for rheumatic diseases in daily practice: a systematic retrospective study of 709 patients
    C Salliot
    Rene Descartes University, Medicine Faculty, AP HP, Cochin Hospital, Rheumatology B Department, Paris, France
    Rheumatology (Oxford) 46:327-34. 2007
    ..To evaluate the rate of infections in rheumatic patients treated with tumour necrosis factor (TNF)-alpha blockers in daily practice and to determine potential risk factors of infections...
  67. ncbi Dissemination and evaluation of the ASAS/EULAR recommendations for the management of ankylosing spondylitis: results of a study among 1507 rheumatologists
    L Gossec
    Paris Descartes University, Medicine Faculty, UPRES EA 4058 APHP, Rheumatology B Department, Cochin Hospital, Paris, France
    Ann Rheum Dis 67:782-8. 2008
    ..Ten ASAS/EULAR recommendations for the management of ankylosing spondylitis (AS) were published in 2006...
  68. ncbi HLA DRB1*01 and DRB1*04 phenotyping does not predict the need for joint surgery in rheumatoid arthritis. A retrospective quantitative evaluation of 300 French patients
    L Gossec
    Service de Rhumatologie B, Universite Rene Descartes, Centre Hospitalier Universitaire Cochin, Paris, France
    Clin Exp Rheumatol 22:462-4. 2004
    ..To determine if the presence of HLA-DR disease-associated epitopes predicts the need for total joint arthroplasty or joint fusion in rheumatoid arthritis (RA)...
  69. ncbi OARSI-OMERACT definition of relevant radiological progression in hip/knee osteoarthritis
    P Ornetti
    Universite de Bourgogne, Medicine Faculty, Dijon University Hospital, Rheumatology Department, Dijon, France
    Osteoarthritis Cartilage 17:856-63. 2009
    ....
  70. ncbi Elaboration of the preliminary Rheumatoid Arthritis Impact of Disease (RAID) score: a EULAR initiative
    L Gossec
    Paris Descartes University, Medicine Faculty, UPRES EA 4058, APHP, Rheumatology B Department, Cochin Hospital, Paris France
    Ann Rheum Dis 68:1680-5. 2009
    ..Current response criteria in rheumatoid arthritis (RA) usually assess only three patient-reported outcomes (PROs): pain, functional disability and patient global assessment. Other important PROs such as fatigue are not included...
  71. ncbi Which variables best predict change in rheumatoid arthritis therapy in daily clinical practice?
    Martin Soubrier
    Service de Rhumatologie, Hopital G Montpied, Clermont Ferrand, France
    J Rheumatol 33:1243-6. 2006
    ..To determine in clinical practice which clinical status variables for rheumatoid arthritis (RA) are most closely associated with a change in disease modifying antirheumatic drug (DMARD) therapy...
  72. ncbi Recommendations of the French Society for Rheumatology. TNFalpha antagonist therapy in rheumatoid arthritis
    Bruno Fautrel
    Service de Rhumatologie, Groupe Hospitalier Pitie Salpetriere, UFR de Medecine, Universite Pierre et Marie Curie Paris VI, 83, Boulevard de l Hopital, 75651 Paris Cedex 13, France
    Joint Bone Spine 73:433-41. 2006
    ..To develop recommendations for TNFalpha-antagonist therapy in patients with rheumatoid arthritis (RA) seen in everyday practice, under the aegis of the French Society for Rheumatology...
  73. ncbi Quantitative ultrasound in postmenopausal osteoporosis
    C Roux
    Centre d Evaluation des Maladies Osseuses, Departement de Rhumatologie, Hopital Cochin, Universite Rene Descartes, Paris, France
    Curr Opin Rheumatol 12:336-45. 2000
    ..Monitoring of skeletal changes and treatment effects by ultrasound cannot be recommended...
  74. ncbi Calcitonin in glucocorticoid-induced osteoporosis
    C Roux
    Departement de Rhumatologie, , , Paris, France
    Front Horm Res 30:145-9. 2002
  75. ncbi Using patients' and rheumatologists' opinions to specify a short form of the WOMAC function subscale
    F Tubach
    Département d Epidémiologie, Biostatistique et Recherche Clinique, Groupe Hopitalier Bichat Claude Bernard, 75018 Paris, France
    Ann Rheum Dis 64:75-9. 2005
    ..Reducing the number of items of the subscale would enhance efficiency and compliance, particularly for use in clinical practice applications...
  76. ncbi Initiation of biological agents in patients with ankylosing spondylitis: results of a Delphi study by the ASAS Group
    T Pham
    , AP-HP, Rheumatology B Department, Cochin Hospital, Paris, France
    Ann Rheum Dis 62:812-6. 2003
    ..Further studies are required to assess their relevance and their consistency with clinical practice...
  77. ncbi Influence of medial meniscectomy on tibiofemoral joint space width
    X Ayral
    Service de Rhumatologie B, Hopital Cochin, Assistance Publique Hopitaux de Paris, Universite Rene Descartes, Paris, France
    Osteoarthritis Cartilage 11:285-9. 2003
    ..The aim of this study was to evaluate the influence of partial medial meniscectomy on tibiofemoral joint space width (JSW)...
  78. ncbi Evaluation of clinically relevant changes in patient reported outcomes in knee and hip osteoarthritis: the minimal clinically important improvement
    F Tubach
    Institut National de la Sante et de la Recherche Medicale, Département d Epidémiologie, Biostatistique et Recherche Clinique, 75018 Paris, France
    Ann Rheum Dis 64:29-33. 2005
    ..In clinical trials, at the group level, results are usually reported as mean and standard deviation of the change in score, which is not meaningful for most readers...
  79. ncbi Intra-articular treatments in osteoarthritis: from the symptomatic to the structure modifying
    L Gossec
    René Discartes University, Cochin Hospital, Rheumatology B Department, Paris, France
    Ann Rheum Dis 63:478-82. 2004
    ..Hyaluronan has delayed onset of efficacy but its benefit for pain may be longer lasting. Lavage and debridement are probably not as efficacious as once thought in osteoarthritis...
  80. ncbi Arthroscopic evaluation of potential structure-modifying drug in osteoarthritis of the knee. A multicenter, randomized, double-blind comparison of tenidap sodium vs piroxicam
    X Ayral
    Service de Rhumatologie B, Hopital Cochin, Assistance Publique Hopitaux de Paris, Universite Rene Descartes, Paris, France
    Osteoarthritis Cartilage 11:198-207. 2003
    ..To test the hypothesis that tenidap has a structure-modifying effect in human knee osteoarthritis...
  81. ncbi Evaluation of clinically relevant states in patient reported outcomes in knee and hip osteoarthritis: the patient acceptable symptom state
    F Tubach
    Institut National de la Santé et de la Recherche Médicale E 0357, Département d Epidémiologie, Biostatistique et Recherche Clinique, 75018 Paris, France
    Ann Rheum Dis 64:34-7. 2005
    ..The patient acceptable symptom state (PASS) is the value beyond which patients can consider themselves well. This concept can help in interpreting results of clinical trials...
  82. ncbi Infliximab in spondylarthropathy--influence on bone density
    E Demis
    Rheumatology Department, , Cochin Hospital, Paris, France
    Clin Exp Rheumatol 20:S185-6. 2002
    ..There was an increase in osteocalcin between baseline and week 6. These data suggest a benefit of anti-TNFalpha therapy on BMD in patients with SpA, may be through an uncoupling effect on bone cells...
  83. ncbi Efficacy of infliximab in refractory ankylosing spondylitis: results of a six-month open-label study
    M Breban
    Institut de Rhumatologie, , , Paris, France
    Rheumatology (Oxford) 41:1280-5. 2002
    ..Relapse usually occurred after discontinuation of the drug, but almost one-third of completers were still free of relapse 4 months after the last infusion...
  84. ncbi OARSI/OMERACT criteria of being considered a candidate for total joint replacement in knee/hip osteoarthritis as an endpoint in clinical trials evaluating potential disease modifying osteoarthritic drugs
    Maxime Dougados
    Paris Descartes University, Medicine Faculty, UPRES EA 4058, AP HP, Cochin Hospital, Rheumatology B Department, Paris, France
    J Rheumatol 36:2097-9. 2009
    ..We propose a composite index including structural and symptomatic variables of osteoarthritis (OA) as criteria for being considered a candidate for total joint replacement as an endpoint in clinical trials evaluating potential DMOAD...
  85. ncbi Evaluation of two strategies (initial methotrexate monotherapy vs its combination with adalimumab) in management of early active rheumatoid arthritis: data from the GUEPARD trial
    Martin Soubrier
    Department of Rheumatology, Hopital G Montpied, 63003 Clermont Ferrand, France
    Rheumatology (Oxford) 48:1429-34. 2009
    ..To compare this strategy with an initial combination of MTX and adalimumab (ADA) given for 3 months and then adjusted based on the disease activity status...
  86. ncbi Feeling good rather than feeling better matters more to patients
    Florence Tubach
    Assistance Publique Hopitaux de Paris, Hopital Bichat, INSERM U738, Universite Paris 7 Denis Diderot, Paris, France
    Arthritis Rheum 55:526-30. 2006
    ....
  87. ncbi Effect of a collective educational program for patients with rheumatoid arthritis: a prospective 12-month randomized controlled trial
    Janine Sophie Giraudet-Le Quintrec
    AP HP, Hopital Cochin, Universite Rene Descartes, Faculte de Medecine, Paris, France
    J Rheumatol 34:1684-91. 2007
    ..To evaluate the effect on health and functional status of an 8-week group-education program for rheumatoid arthritis (RA) in addition to usual medical care...
  88. ncbi Retention rates of tumor necrosis factor blockers in daily practice in 770 rheumatic patients
    Muriel Duclos
    Rene Descartes University, Faculty of Medicine, Paris, France
    J Rheumatol 33:2433-8. 2006
    ..Moreover, results suggest greater benefit in SpA. The role of concomitant DMARD remains to be confirmed...
  89. ncbi Practice patterns in outpatient rheumatology: a pilot evaluation of medical file content
    Jacques Fechtenbaum
    Rheumatology Department B, Cochin Teaching Hospital, AP HP, and René Descartes Paris V University, Paris, France
    Joint Bone Spine 74:171-4. 2007
    ..Subsequently, one of the RHEVER members investigated whether these recommendations were followed by RHEVER participants at a teaching hospital...
  90. ncbi OMERACT/OARSI initiative to define states of severity and indication for joint replacement in hip and knee osteoarthritis
    Laure Gossec
    Medicine Faculty, Paris 5 René Descartes University AP HP, Cochin Hospital, Department of Rheumatology B, Paris, France
    J Rheumatol 34:1432-5. 2007
    ..quot;..
  91. ncbi Impact of ultrasound imaging on local corticosteroid injections of symptomatic ankle, hind-, and mid-foot in chronic inflammatory diseases
    Xavier Ayral
    Cochin Hospital, , Paris, France
    Arthritis Rheum 53:284-92. 2005
    ..0170). CONCLUSION: US frequently led the physician to change his diagnosis of inflammatory lesions in painful foot, and consequently his planning of CS injections. Moreover, US could improve the response to local treatment...
  92. ncbi Flory syndrome or lymphomonocytic/low-neutrophil oligoarthritis: a diagnosis or a prognosis?
    Bernard Amor
    Rheumatology Department, Hopital Cochin, 27, rue du Faubourg Saint Jacques, 75014 Paris, France
    Joint Bone Spine 70:122-7. 2003
    ..To individualize a new clinical entity of chronic arthritis and/or a factor indicating good prognosis of chronic arthritis...
  93. ncbi Effects of video information on preoperative anxiety level and tolerability of joint lavage in knee osteoarthritis
    Xavier Ayral
    Service de Rhumatologie B, Hopital Cochin AP HP, Universite Rene Descartes, Paris, France
    Arthritis Rheum 47:380-2. 2002
    ..To investigate the impact of video information on preoperative anxiety of patients scheduled to undergo joint lavage for knee osteoarthritis, and tolerability of the lavage...
  94. ncbi Intraarticular glucocorticoid injections in rapidly destructive hip osteoarthritis
    Caroline Villoutreix
    Rheumatology B Department, Cochin Teaching Hospital, Assistance Publique des Hopitaux de Paris, René Descartes Paris V University, France
    Joint Bone Spine 73:66-71. 2006
    ....
  95. ncbi Minimal clinically important difference, low disease activity state, and patient acceptable symptom state: methodological issues
    Florence Tubach
    , Biostatistique et Recherche Clinique, Groupe Hospitalier Bichat-Claude Bernard (AP-HP, INSERM U738, , Paris, France
    J Rheumatol 32:2025-9. 2005
    ..Threshold values for the MCID and LDAS should be determined according to data-driven and experts' opinions and approaches...
  96. ncbi Diagnostic and predictive value of anti-cyclic citrullinated protein antibodies in rheumatoid arthritis: a systematic literature review
    J Avouac
    , Medicine Faculty, and APHP Cochin Hospital, Rhumatologie B Department, Paris, France
    Ann Rheum Dis 65:845-51. 2006
    ..Moreover, anti-CCP antibodies appear to be highly predictive of the future development of RA in both healthy subjects and patients with undifferentiated arthritis...
  97. ncbi What are the best markers for disease progression in osteoarthritis (OA)?
    P P Cheung
    Paris Descartes University, Medicine Faculty, UPRES EA 4058, APHP, Rheumatology B Department, Cochin Hospital, Paris, France
    Best Pract Res Clin Rheumatol 24:81-92. 2010
    ..Prognostic factors of progression are reviewed here, mainly for hip and knee osteoarthritis as most data available concern these localisations. Areas of further research are highlighted...
  98. ncbi A hyaluronan preparation (500-730 kDa) in the treatment of osteoarthritis: a review of clinical trials with Hyalgan
    E Maheu
    Department of Rheumatology, Cochin Hospital, Universite Rene Descartes, Paris, France
    Int J Clin Pract 56:804-13. 2002
    ..However, further studies of Hyalgan in OA in other joints, and in damaged joints in rheumatoid arthritis, are needed...
  99. ncbi Sodium hyaluronate therapy in osteoarthritis: arguments for a potential beneficial structural effect
    M Dougados
    , Clinique de Rhumatologie, , Paris, France
    Semin Arthritis Rheum 30:19-25. 2000
    ..However, further clinical studies are needed to determine whether these effects are valuable in altering the progression of OA...
  100. ncbi Diacerein as a disease-modulating agent in osteoarthritis
    G Falgarone
    , Cochin Hospital, Rheumatology B Department, 27 rue du Faubourg Saint Jacques, 75014 Paris, France
    Curr Rheumatol Rep 3:479-83. 2001
    ..However, clinical trials using new sets of criteria could be conducted to estimate the structural modulating effect of diacerein; experimental studies must be performed to understand this effect...
  101. ncbi Adverse events associated with rofecoxib therapy: results of a large study in community-derived osteoarthritic patients
    Bernard Bannwarth
    Department of Rheumatology, Groupe Hospitalier Pellegrin and Division of Therapeutics, Universite Victor Segalen, Bordeaux, France
    Drug Saf 26:49-54. 2003
    ..To evaluate the safety profile of rofecoxib, a selective cyclo-oxygenase-2 inhibitor, in patients with osteoarthritis who are receiving care in non-hospital practice settings...