Olivia Doppelt-Azeroual

Summary

Country: France

Publications

  1. pmc Analysis of HSP90-related folds with MED-SuMo classification approach
    Olivia Doppelt-Azeroual
    MEDIT SA, 2 rue du Belvédère, Palaiseau, France
    Drug Des Devel Ther 3:59-72. 2009
  2. doi request reprint Computational fragment-based drug design to explore the hydrophobic sub-pocket of the mitotic kinesin Eg5 allosteric binding site
    Ksenia Oguievetskaia
    MEDIT SA, 2 rue du Belvédère, 91120, Palaiseau, France
    J Comput Aided Mol Des 23:571-82. 2009
  3. doi request reprint Computational fragment-based approach at PDB scale by protein local similarity
    Fabrice Moriaud
    MEDIT SA, 2 rue du Belvédère, 91120 Palaiseau, France
    J Chem Inf Model 49:280-94. 2009
  4. ncbi request reprint A review of MED-SuMo applications
    Olivia Doppelt-Azeroual
    MEDIT SA, 2 rue du Belvédère, 91120 Palaiseau, France
    Infect Disord Drug Targets 9:344-57. 2009

Collaborators

Detail Information

Publications4

  1. pmc Analysis of HSP90-related folds with MED-SuMo classification approach
    Olivia Doppelt-Azeroual
    MEDIT SA, 2 rue du Belvédère, Palaiseau, France
    Drug Des Devel Ther 3:59-72. 2009
    ..The different clusters created by MED-SMA yield interesting observations. For instance, one cluster gathers three types of proteins (HSP90, topoisomerase VI, and BCK) which all bind the drug radicicol...
  2. doi request reprint Computational fragment-based drug design to explore the hydrophobic sub-pocket of the mitotic kinesin Eg5 allosteric binding site
    Ksenia Oguievetskaia
    MEDIT SA, 2 rue du Belvédère, 91120, Palaiseau, France
    J Comput Aided Mol Des 23:571-82. 2009
    ..Some of the latter having original scaffolds and substituents in the hydrophobic pocket are identified in libraries of synthetically accessible molecules by the MED-Search software...
  3. doi request reprint Computational fragment-based approach at PDB scale by protein local similarity
    Fabrice Moriaud
    MEDIT SA, 2 rue du Belvédère, 91120 Palaiseau, France
    J Chem Inf Model 49:280-94. 2009
    ..The results show the potential for finding relevant leads from any protein 3D structure since the occurrence of interfamily MED-Portions is 25% for protein kinase and almost 100% for the GPCR...
  4. ncbi request reprint A review of MED-SuMo applications
    Olivia Doppelt-Azeroual
    MEDIT SA, 2 rue du Belvédère, 91120 Palaiseau, France
    Infect Disord Drug Targets 9:344-57. 2009
    ..These further cases include drug repurposing and fragment-based drug design...