Philippe Dieude

Summary

Country: France

Publications

  1. doi request reprint Phenotype-haplotype correlation of IRF5 in systemic sclerosis: role of 2 haplotypes in disease severity
    Philippe Dieude
    Service de Rhumatologie, Hopital Bichat Claude Bernard, APHP, Université Diderot Paris 7, Paris, France
    J Rheumatol 37:987-92. 2010
  2. pmc Epistatic interaction between BANK1 and BLK in rheumatoid arthritis: results from a large trans-ethnic meta-analysis
    Emmanuelle Genin
    Institut National de la Santé et de la Recherche Médicale UMR S946, Univ Paris Diderot, Paris, France
    PLoS ONE 8:e61044. 2013
  3. pmc The ITGAV rs3738919-C allele is associated with rheumatoid arthritis in the European Caucasian population: a family-based study
    Laurent Jacq
    GenHotel EA3886, Evry Paris VII Universities, 91057 Evry Genopole Cedex, France
    Arthritis Res Ther 9:R63. 2007
  4. doi request reprint Association between the IRF5 rs2004640 functional polymorphism and systemic sclerosis: a new perspective for pulmonary fibrosis
    P Dieude
    Universite Paris 7, and Hôpital Bichat Claude Bernard, Assistance Publique Hopitaux de Paris, Paris, France
    Arthritis Rheum 60:225-33. 2009
  5. doi request reprint Association of the CD226 Ser(307) variant with systemic sclerosis: evidence of a contribution of costimulation pathways in systemic sclerosis pathogenesis
    P Dieude
    Universite Paris Diderot, Hopital Bichat Claude Bernard, Paris, France
    Arthritis Rheum 63:1097-105. 2011
  6. doi request reprint NLRP1 influences the systemic sclerosis phenotype: a new clue for the contribution of innate immunity in systemic sclerosis-related fibrosing alveolitis pathogenesis
    P Dieude
    Service de Rhumatologie, Paris Diderot University, INSERM U699, Hopital Bichat Claude Bernard, 46 rue Henri Huchard, 75018 Paris, France
    Ann Rheum Dis 70:668-74. 2011
  7. doi request reprint STAT4 is a genetic risk factor for systemic sclerosis having additive effects with IRF5 on disease susceptibility and related pulmonary fibrosis
    P Dieude
    Université Paris 7 and Service de Rhumatologie, Hopital Bichat Claude Bernard, Assistance Publique Hopitaux de Paris, Paris, France
    Arthritis Rheum 60:2472-9. 2009
  8. doi request reprint Evidence of the contribution of the X chromosome to systemic sclerosis susceptibility: association with the functional IRAK1 196Phe/532Ser haplotype
    P Dieude
    Paris Diderot University, AP HP, INSERM U699, Paris, France
    Arthritis Rheum 63:3979-87. 2011
  9. doi request reprint Rheumatic diseases: environment and genetics
    Philippe Dieude
    LREPR EA3886, Evry Genopole, Universite d Evry Val d Essonne, Evry, France
    Joint Bone Spine 76:602-7. 2009
  10. doi request reprint The PTPN22 620W allele confers susceptibility to systemic sclerosis: findings of a large case-control study of European Caucasians and a meta-analysis
    P Dieude
    Universite Paris 7, Paris, France
    Arthritis Rheum 58:2183-8. 2008

Detail Information

Publications56

  1. doi request reprint Phenotype-haplotype correlation of IRF5 in systemic sclerosis: role of 2 haplotypes in disease severity
    Philippe Dieude
    Service de Rhumatologie, Hopital Bichat Claude Bernard, APHP, Université Diderot Paris 7, Paris, France
    J Rheumatol 37:987-92. 2010
    ..Our aim was to investigate whether IRF5 haplotypes confer susceptibility to SSc, and to perform genotype haplotype-phenotype correlation analyses...
  2. pmc Epistatic interaction between BANK1 and BLK in rheumatoid arthritis: results from a large trans-ethnic meta-analysis
    Emmanuelle Genin
    Institut National de la Santé et de la Recherche Médicale UMR S946, Univ Paris Diderot, Paris, France
    PLoS ONE 8:e61044. 2013
    ..To ascertain the real impact of BANK1 on RA genetic susceptibility, we performed a large meta-analysis including our original data and tested for an epistatic interaction between BANK1 and BLK in RA susceptibility...
  3. pmc The ITGAV rs3738919-C allele is associated with rheumatoid arthritis in the European Caucasian population: a family-based study
    Laurent Jacq
    GenHotel EA3886, Evry Paris VII Universities, 91057 Evry Genopole Cedex, France
    Arthritis Res Ther 9:R63. 2007
    ..002, odds ratio = 1.94, 95% confidence interval = 1.3-2.9). The rs3738919-C allele of the ITGAV gene is associated with RA in the European Caucasian population, suggesting ITGAV as a new minor RA susceptibility gene...
  4. doi request reprint Association between the IRF5 rs2004640 functional polymorphism and systemic sclerosis: a new perspective for pulmonary fibrosis
    P Dieude
    Universite Paris 7, and Hôpital Bichat Claude Bernard, Assistance Publique Hopitaux de Paris, Paris, France
    Arthritis Rheum 60:225-33. 2009
    ..The aim of this study was to determine whether the IRF5 rs2004640 single-nucleotide polymorphism is associated with SSc...
  5. doi request reprint Association of the CD226 Ser(307) variant with systemic sclerosis: evidence of a contribution of costimulation pathways in systemic sclerosis pathogenesis
    P Dieude
    Universite Paris Diderot, Hopital Bichat Claude Bernard, Paris, France
    Arthritis Rheum 63:1097-105. 2011
    ..The purpose of this study was to test for association of the CD226 rs763361 polymorphism with systemic sclerosis (SSc) in European Caucasian populations...
  6. doi request reprint NLRP1 influences the systemic sclerosis phenotype: a new clue for the contribution of innate immunity in systemic sclerosis-related fibrosing alveolitis pathogenesis
    P Dieude
    Service de Rhumatologie, Paris Diderot University, INSERM U699, Hopital Bichat Claude Bernard, 46 rue Henri Huchard, 75018 Paris, France
    Ann Rheum Dis 70:668-74. 2011
    ..NLRP1 provides a scaffold for the assembly of the inflammasome that promotes the processing and maturation of pro-IL-1β. In addition, NLRP1 variants were found to confer susceptibility to autoimmune disorders...
  7. doi request reprint STAT4 is a genetic risk factor for systemic sclerosis having additive effects with IRF5 on disease susceptibility and related pulmonary fibrosis
    P Dieude
    Université Paris 7 and Service de Rhumatologie, Hopital Bichat Claude Bernard, Assistance Publique Hopitaux de Paris, Paris, France
    Arthritis Rheum 60:2472-9. 2009
    ..The aim of this study was to determine whether the STAT4 rs7574865 single-nucleotide polymorphism is associated with SSc, and whether it interacts with IRF5...
  8. doi request reprint Evidence of the contribution of the X chromosome to systemic sclerosis susceptibility: association with the functional IRAK1 196Phe/532Ser haplotype
    P Dieude
    Paris Diderot University, AP HP, INSERM U699, Paris, France
    Arthritis Rheum 63:3979-87. 2011
    ..This study was undertaken to test for an association between SSc and the IRAK1 SLE risk haplotype...
  9. doi request reprint Rheumatic diseases: environment and genetics
    Philippe Dieude
    LREPR EA3886, Evry Genopole, Universite d Evry Val d Essonne, Evry, France
    Joint Bone Spine 76:602-7. 2009
    ..The past decade has witnessed an impressive accumulation of data on the determinism of complex diseases, and the next will probably bring further insights into the pathophysiology of dys/autoimmune diseases...
  10. doi request reprint The PTPN22 620W allele confers susceptibility to systemic sclerosis: findings of a large case-control study of European Caucasians and a meta-analysis
    P Dieude
    Universite Paris 7, Paris, France
    Arthritis Rheum 58:2183-8. 2008
    ..We then conducted a meta-analysis of the most recent studies of SSc in order to verify the association or lack of association between the PTPN22 1858C>T variant and SSc...
  11. pmc The TNFRSF1A R92Q mutation is frequent in rheumatoid arthritis but shows no evidence for association or linkage with the disease
    Philippe Dieude
    Service de Rhumatologie, Hopital Bichat Claude Bernard, 46 rue Henri Huchard, Paris 75018, France
    Ann Rheum Dis 66:1113-5. 2007
    ..A recent study suggested that the R92Q mutation was associated with polyarthritis. We aimed to search for this and other TNFRSF1A mutations in rheumatoid arthritis (RA), and to test for linkage...
  12. doi request reprint Association of metalloproteinase gene polymorphisms with systemic sclerosis in the European Caucasian population
    Julien Wipff
    Universite Paris Descartes, AP HP, Hopital Cochin, France
    J Rheumatol 37:599-602. 2010
    ..Our aim was to determine whether polymorphisms of the MMP2, MMP9, and MMP14 genes confer susceptibility to SSc in a large population...
  13. ncbi request reprint A TNFR1 genotype with a protective role in familial rheumatoid arthritis
    Philippe Dieude
    GenHotel, Evry Genopole, France
    Arthritis Rheum 50:413-9. 2004
    ..TNFR1 is mutated in TNFR-associated periodic syndrome (TRAPS). We undertook this study to test the TNFR1 exonic polymorphism closest to the TRAPS mutations site (+36 A/G) for association with RA...
  14. doi request reprint Angiotensin-converting enzyme gene does not contribute to genetic susceptibility to systemic sclerosis in European Caucasians
    Julien Wipff
    Paris Descartes Université, Rhumatologie A, Hopital Cochin, AP HP, Paris, France
    J Rheumatol 36:337-40. 2009
    ..To determine whether angiotensin-converting enzyme (ACE) polymorphisms including I/D and 2 single-nucleotide polymorphisms (SNP) affect susceptibility to systemic sclerosis (SSc) in a large French Caucasian population...
  15. doi request reprint Variants of the xeroderma pigmentosum variant gene (POLH) are associated with melanoma risk
    Julie Di Lucca
    Laboratoire de Biochimie hormonale et génétique, Hopital Bichat Claude Bernard, APHP, IFR02, Universite Paris, Henri Huchard, 75018 Paris, France
    Eur J Cancer 45:3228-36. 2009
    ..XPV results from mutations of the POLH gene that encodes a DNA translesion polymerase. In this work, we tested the hypothesis that POLH variants could be associated with melanoma risk...
  16. doi request reprint C8orf13-BLK is a genetic risk locus for systemic sclerosis and has additive effects with BANK1: results from a large french cohort and meta-analysis
    Baptiste Coustet
    Inserm U1016, Universite Paris Descartes, Paris, France
    Arthritis Rheum 63:2091-6. 2011
    ....
  17. ncbi request reprint Association study of B-cell marker gene polymorphisms in European Caucasian patients with systemic sclerosis
    Karen Dawidowicz
    Universite Paris Diderot, Hopital Bichat Claude Bernard, Assistance Publique Hopitaux de Paris AP HP, Paris, France
    Clin Exp Rheumatol 29:839-42. 2011
    ..BANK1 and BLK B-cell genetic markers have been reproducibly and convincingly found to contribute to susceptibility to systemic sclerosis (SSc)...
  18. pmc Association study of ITGAM, ITGAX, and CD58 autoimmune risk loci in systemic sclerosis: results from 2 large European Caucasian cohorts
    Baptiste Coustet
    Universite Paris Descartes, Rhumatologie A, Hopital Cochin, APHP, Paris, France
    J Rheumatol 38:1033-8. 2011
    ..To determine whether novel risk loci associated with systemic lupus erythematosus or multiple sclerosis may confer susceptibility to SSc, we tested single-nucleotide polymorphisms (SNP) from ITGAM, ITGAX, and CD58 for associations...
  19. doi request reprint A regulatory variant in CCR6 is associated with susceptibility to antitopoisomerase-positive systemic sclerosis
    Eugénie Koumakis
    INSERM, Institut Cochin, Cochin Hospital, AP HP, Inserm U1016, Sorbonne Paris Cité, and Paris Descartes University, Paris, France
    Arthritis Rheum 65:3202-8. 2013
    ..The present study was thus undertaken to investigate whether CCR6 polymorphisms could also be associated with susceptibility to SSc...
  20. pmc Rheumatoid arthritis seropositive for the rheumatoid factor is linked to the protein tyrosine phosphatase nonreceptor 22-620W allele
    Philippe Dieude
    GenHotel EA3886, Evry Genopole, Evry, France
    Arthritis Res Ther 7:R1200-7. 2005
    ..This study is the first to show linkage of PTPN22 to RF+ RA, consistent with PTPN22 as a new RA gene...
  21. doi request reprint High levels of anti-cyclic citrullinated peptide autoantibodies are associated with co-occurrence of pulmonary diseases with rheumatoid arthritis
    Fleur Aubart
    Service de Rhumatologie, Hopital Bichat Claude Bernard, 46 rue Henri Huchard, 75018 Paris, France
    J Rheumatol 38:979-82. 2011
    ..To investigate whether levels of anti-cyclic citrullinated peptide antibodies (anti-CCP2) in patients with rheumatoid arthritis (RA) are associated with the co-occurrence of lung diseases...
  22. ncbi request reprint Association study of 3 rheumatoid arthritis risk loci in systemic sclerosis in European Caucasian population
    Baptiste Coustet
    Inserm U1016, Universite Paris Descartes, Hopital Cochin, Paris, France
    Clin Exp Rheumatol 29:S6-9. 2011
    ..Systemic sclerosis (SSc) belongs to connective tissue disorders and recent data have highlighted strong associations with some autoimmunity genes shared with other autoimmune diseases...
  23. doi request reprint Prospective cohort study of effects of infliximab on rheumatoid factor, anti-cyclic citrullinated peptide antibodies and antinuclear antibodies in patients with long-standing rheumatoid arthritis
    Alexandra Bruns
    Rheumatology Department, Bichat Teaching Hospital, AP HP, CHU Bichat, 46 rue Henri Huchard, 75018 Paris, France
    Joint Bone Spine 76:248-53. 2009
    ....
  24. doi request reprint Brief report: candidate gene study in systemic sclerosis identifies a rare and functional variant of the TNFAIP3 locus as a risk factor for polyautoimmunity
    Eugénie Koumakis
    Paris Descartes University, Inserm U1016, Institut Cochin, and Cochin Hospital, AP HP, Paris, France
    Arthritis Rheum 64:2746-52. 2012
    ..The present study was undertaken to investigate whether rare variants of TNFAIP3 and TREX1 are also associated with SSc...
  25. doi request reprint TGFβ receptor gene variants in systemic sclerosis-related pulmonary arterial hypertension: results from a multicentre EUSTAR study of European Caucasian patients
    Eugénie Koumakis
    Paris Descartes University, Inserm U1016, Institut Cochin, Sorbonne Paris Cité, Paris, France
    Ann Rheum Dis 71:1900-3. 2012
    ..Mutations of transforming growth factor beta (TGFβ) receptor genes strongly contribute to idiopathic and familial PAH...
  26. doi request reprint Prevalence of pulmonary hypertension in systemic sclerosis in European Caucasians and metaanalysis of 5 studies
    Jerome Avouac
    Department of Rheumatology A, Paris Descartes University, Cochin Hospital, APHP, Paris, France
    J Rheumatol 37:2290-8. 2010
    ..To measure the prevalence of different types of pulmonary hypertension (PH) and to identify patients with systemic sclerosis (SSc) at highest risk in a multicenter European sample, with a metaanalysis of relevant studies...
  27. doi request reprint Associated autoimmune diseases in systemic sclerosis define a subset of patients with milder disease: results from 2 large cohorts of European Caucasian patients
    Jerome Avouac
    Rheumatology A Department, Paris Descartes University, Cochin Hospital, Paris, France
    J Rheumatol 37:608-14. 2010
    ..To assess the prevalence and potential associations with the systemic sclerosis (SSc) phenotype of additional autoimmune diseases (AID)...
  28. doi request reprint Prediction of pulmonary hypertension related to systemic sclerosis by an index based on simple clinical observations
    Christophe Meune
    Paris Descartes University and Department of Rheumatology A, Cochin Hospital, AP HP, Paris, France
    Arthritis Rheum 63:2790-6. 2011
    ..To develop a score to estimate the risk of developing pulmonary hypertension (PH) in patients with systemic sclerosis (SSc)...
  29. ncbi request reprint Association study of CRP gene in systemic sclerosis in European Caucasian population
    Julien Wipff
    Rhumatologie A, APHP, Hopital Cochin, Universite Paris Descartes, 27 rue du Faubourg St Jacques, 75014, Paris, France
    Rheumatol Int 34:389-92. 2014
    ..These results obtained through a large cohort of European Caucasian SSc patients do not support the implication of CRP gene in the pathogenesis of SSc. ..
  30. doi request reprint Anti-RNA polymerase III antibody prevalence and associated clinical manifestations in a large series of French patients with systemic sclerosis: a cross-sectional study
    Olivier Meyer
    Universite Paris 7 Denis Diderot, UFR de Medecine, APHP Hôpital Bichat, Service de Rhumatologie, Paris, France
    J Rheumatol 37:125-30. 2010
    ..To determine the prevalence of anti-RNA polymerase III autoantibodies in French patients with systemic sclerosis (SSc) and to identify the associated clinical manifestations...
  31. doi request reprint BANK1 is a genetic risk factor for diffuse cutaneous systemic sclerosis and has additive effects with IRF5 and STAT4
    P Dieude
    Universite Paris 7 Denis Diderot, Hopital Bichat Claude Bernard, Assistance Publique Hopitaux de Paris AP HP, Paris, France
    Arthritis Rheum 60:3447-54. 2009
    ....
  32. doi request reprint Autoantibodies to citrullinated fibrinogen compared with anti-MCV and anti-CCP2 antibodies in diagnosing rheumatoid arthritis at an early stage: data from the French ESPOIR cohort
    Pascale Nicaise-Roland
    UF Immunologie Autoimmunité et Hypersensibilités, APHP Hopital Bichat Claude Bernard, Paris, France
    Ann Rheum Dis 72:357-62. 2013
    ....
  33. pmc Genome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosis
    Yannick Allanore
    Universite Paris Descartes, Rhumatologie A, INSERM, U1016, Hopital Cochin, APHP, Paris, France
    PLoS Genet 7:e1002091. 2011
    ..The genetic signal of association with TNIP1 variants, together with tissular and cellular investigations, suggests that this pathway has a critical role in regulating autoimmunity and SSc pathogenesis...
  34. pmc The MUC5B variant is associated with idiopathic pulmonary fibrosis but not with systemic sclerosis interstitial lung disease in the European Caucasian population
    Raphael Borie
    Service de Pneumologie A, APHP, Hopital Bichat, Paris, France
    PLoS ONE 8:e70621. 2013
    ..This study confirms 1) an association between the T allele risk and IPF, 2) an absence of association with SSc-ILD, suggesting different pathophysiology...
  35. doi request reprint Familial autoimmunity in systemic sclerosis -- results of a French-based case-control family study
    Eugénie Koumakis
    Paris Descartes University, Rheumatology A Department, Cochin Hospital, APHP, France
    J Rheumatol 39:532-8. 2012
    ..To assess the prevalence of autoimmune diseases in first-degree relatives of patients with systemic sclerosis (SSc), and to compare those results with control families in order to identify patterns of autoimmune diseases in relatives...
  36. doi request reprint Variants of the MATP/SLC45A2 gene are protective for melanoma in the French population
    Mickael Guedj
    Laboratoire Statistique et Genome, UMR CNRS 8071, INRA 1152, Universite d Evry Val d Essonne, Evry, France
    Hum Mutat 29:1154-60. 2008
    ..Future studies may show whether genetic information could provide a useful complement to physical examination in predicting melanoma risk...
  37. pmc Independent replication and meta analysis of association studies establish TNFSF4 as a susceptibility gene preferentially associated with the subset of anticentromere-positive patients with systemic sclerosis
    Baptiste Coustet
    Universite Paris Descartes, Rhumatologie A, Inserm U1016, Hopital Cochin, APHP, Paris, France
    J Rheumatol 39:997-1003. 2012
    ..Our objective was to validate TNFSF4 association with SSc and determine the subset with the higher risk...
  38. doi request reprint Prevalence of autoantibodies in SAPHO syndrome: a single-center study of 90 patients
    Céline Grosjean
    Department of Rheumatology and Department of Immunology, Bichat Teaching Hospital, Paris, France
    J Rheumatol 37:639-43. 2010
    ..To determine the prevalence of the most often tested autoantibodies in synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome...
  39. pmc Lack of association between the protein tyrosine phosphatase non-receptor 22 (PTPN22)*620W allele and systemic sclerosis in the French Caucasian population
    J Wipff
    Rheumatology A Department, Cochin Hospital, Paris, France
    Ann Rheum Dis 65:1230-2. 2006
    ..38). The PTPN22*620W allele was also not associated with autoantibody patterns. Thus, the PTPN22*R620W polymorphism cannot be regarded as a genetic susceptibility factor for SSc in the French Caucasian population...
  40. doi request reprint Efficacy of anakinra in calcium pyrophosphate crystal-induced arthritis: a report of 16 cases and review of the literature
    Sebastien Ottaviani
    Service de Rhumatologie, Hopital Bichat, Universite Paris Diderot, AP HP, 46, rue Henri Huchard, 75018 Paris, France
    Joint Bone Spine 80:178-82. 2013
    ..The aim of the study was to evaluate the efficacy and tolerance of anakinra in patients with CPP crystal-induced arthritis...
  41. doi request reprint The interferon regulatory factor 5 gene confers susceptibility to rheumatoid arthritis and influences its erosive phenotype
    Karen Dawidowicz
    GenHotel EA 3886, University Evry Paris 7 Medical School, Member of the AutoCure European Consortium, Evry Genopole Cedex, France
    Ann Rheum Dis 70:117-21. 2011
    ..Interferon regulatory factors, such as IRF5, coordinate type I IFN expression. Multiple IRF5 variants were suggested as autoimmunity susceptibility factors...
  42. doi request reprint Association of the TNFAIP3 rs5029939 variant with systemic sclerosis in the European Caucasian population
    P Dieude
    Universite Paris, Hopital Bichat Claude Bernard, APHP, France
    Ann Rheum Dis 69:1958-64. 2010
    ..TNFAIP3 encodes the ubiquitin-modifying enzyme, a key regulator of inflammatory signalling pathways. Convincing associations between TNFAIP3 variants and autoimmune diseases have been reported...
  43. ncbi request reprint Ultrasonography of shoulders in spondyloarthritis and rheumatoid arthritis: a case-control study
    Sebastien Ottaviani
    Service de Rhumatologie, Universite Paris Diderot, Hopital Bichat, AP HP, 46, rue Henri Huchard, 75018 Paris, France Electronic address
    Joint Bone Spine 81:247-9. 2014
    ..A recent ultrasound study showed that ultrasonography (US) of the hands might differentiate psoriatic arthritis to RA. The aim of the study was to compare different US features in SpA, RA and healthy controls...
  44. doi request reprint Inflammation and disease activity are associated with high circulating cardiac markers in rheumatoid arthritis independently of traditional cardiovascular risk factors
    Jerome Avouac
    From the Paris Descartes University, Sorbonne Paris Cité, Rheumatology A Department, Cochin Hospital Paris Descartes University, INSERM U1016 and CNRS UMR8104, Cochin Institute, Paris Paris 13 University, University Hospital of Paris Seine Saint Denis, Cardiology Department, Bobigny Clinical Chemistry Laboratory, Cochin and Hôtel Dieu Hospitals Paris 7 University, Rheumatology Department, Bichat Claude Bernard Hospital Clinical Chemistry and Hormonology Department, Tenon Hospital, Paris, France
    J Rheumatol 41:248-55. 2014
    ..To measure concentrations of high-sensitivity cardiac troponin (HS-cTnT) and N-terminal pro-brain natriuretic peptide (NT-proBNP) in patients with rheumatoid arthritis (RA) and to examine correlates...
  45. pmc Body mass index influences the response to infliximab in ankylosing spondylitis
    Sebastien Ottaviani
    Rheumatology Department, AP HP, Paris Diderot, Sorbonne Paris Cité University, Bichat Claude Bernard Hospital, 46 rue Henri Huchard, Paris, 75018, France
    Arthritis Res Ther 14:R115. 2012
    ..The aim of this study was to determine whether body mass index (BMI) affects response to infliximab (IFX) in ankylosing spondylitis (AS) patients...
  46. pmc Anti-C1q antibodies antedate patent active glomerulonephritis in patients with systemic lupus erythematosus
    Olivier C Meyer
    Rheumatology Unit, Bichat Hospital, APHP, 75018 Paris, France
    Arthritis Res Ther 11:R87. 2009
    ..Autoantibodies against C1q correlate with lupus nephritis. We compared titers of anti-C1q and anti-dsDNA in 70 systemic lupus erythematosus patients with (n = 15) or without (n = 55) subsequent biopsy-proven lupus nephritis...
  47. ncbi request reprint Association between tumor necrosis factor receptor II and familial, but not sporadic, rheumatoid arthritis: evidence for genetic heterogeneity
    Philippe Dieude
    GenHotel, Evry Genopole, France
    Arthritis Rheum 46:2039-44. 2002
    ..The present study was undertaken to test this association in the French Caucasian population...
  48. doi request reprint Updating the genetics of systemic sclerosis
    Yannick Allanore
    Universite Paris Descartes, Service de Rhumatologie A, Hopital Cochin, France
    Curr Opin Rheumatol 22:665-70. 2010
    ..In this review, we focus on recent large candidate gene studies that have included replication and very recent genome-wide approaches...
  49. ncbi request reprint Association study of serotonin transporter gene (SLC6A4) in systemic sclerosis in European Caucasian populations
    Julien Wipff
    Service de Rhumatologie A, Hopital Cochin, 27 rue du Faubourg St Jacques, 75014 Paris, France
    J Rheumatol 37:1164-7. 2010
    ..Our objective was to determine whether polymorphisms of SLC6A4 confer susceptibility to SSc and its vascular phenotype...
  50. doi request reprint Genetic background of systemic sclerosis: autoimmune genes take centre stage
    Yannick Allanore
    Universite Paris Descartes, Service de Rhumatologie A, Hopital Cochin, 27 rue du Faubourg St Jacques, 75014 Paris, France
    Rheumatology (Oxford) 49:203-10. 2010
    ..Most likely, these immune-modifying genes could interact and influence both disease phenotype and severity. Less evidence is available yet with regard to genetic markers relating to the vascular and fibrotic aspects of the disease...
  51. doi request reprint Association of a KCNA5 gene polymorphism with systemic sclerosis-associated pulmonary arterial hypertension in the European Caucasian population
    J Wipff
    Universite Paris Descartes, INSERM U781, Hopital Necker, and Hôpital Cochin, Paris, France
    Arthritis Rheum 62:3093-100. 2010
    ..We undertook this study to determine whether KCNA5 polymorphisms confer susceptibility to SSc and its vascular phenotype, including PAH...
  52. pmc Antibodies to mutated citrullinated vimentin for diagnosing rheumatoid arthritis in anti-CCP-negative patients and for monitoring infliximab therapy
    Pascale Nicaise Roland
    Immunology and Haematology Department, Bichat Claude Bernard Teaching Hospital, AP HP, Paris Cedex 18, France
    Arthritis Res Ther 10:R142. 2008
    ..The aims of this study were to evaluate the usefulness of anti-MCV for diagnosing RA in anti-CCP-negative patients and to monitor anti-MCV titres during infliximab therapy for RA...
  53. doi request reprint Rheumatic and musculoskeletal features of Whipple disease: a report of 29 cases
    Marine Meunier
    From the Paris Descartes University, Rheumatology A Department and Rheumatology B Department, Cochin Hospital, AP HP, Paris Rheumatology Department, Le Mans Hospital Rheumatology Department, CHU Angers Rheumatology Department, CHU Clermont Ferrand Rheumatology Department, Bichat Hospital, AP HP, Paris Rheumatology Department, CHU Nantes Unità di Reumatologia, Azienda Ospedaliera Universitaria Integrata, Verona, Italy Rheumatology Department, CHU Strasbourg and the Rheumatology Department, Teaching Hospital of Lapeyronie and University of Montpellier, France
    J Rheumatol 40:2061-6. 2013
    ..We report cases of Whipple disease with rheumatic symptoms and describe their clinical presentation, modes of diagnosis, and outcomes...
  54. pmc Genotype/phenotype analyses for 53 Crohn's disease associated genetic polymorphisms
    Camille Jung
    Universite Paris Diderot, UMR843, Paris, France
    PLoS ONE 7:e52223. 2012
    ..However, the impact of these associations in clinical practice remains to be defined. The aim of the study was to analyse the relationship between genotypes and phenotypes for the main 53 CD-associated polymorphisms...
  55. ncbi request reprint Sensory neuropathy revealing necrotizing vasculitis during infliximab therapy for rheumatoid arthritis
    Pascal Richette
    Federation de rhumatologie, Hopital Lariboisiere, Paris, France
    J Rheumatol 31:2079-81. 2004
    ....
  56. doi request reprint Comparison of pain, pain burden, coping strategies, and attitudes between patients with systemic sclerosis and patients with rheumatoid arthritis: a cross-sectional study
    Serge Perrot
    Service de Médecine Interne et Thérapeutique, Centre de la Douleur, Hotel Dieu, Assistance Publique Hopitaux de Paris, Universite Paris Descartes, INSERM U 987, Paris, France
    Pain Med 14:1776-85. 2013
    ..To analyze pain in systemic sclerosis (SSc), especially its impact and coping strategies, compared with the reference painful inflammatory rheumatological condition, rheumatoid arthritis (RA)...