Research Topics

Genomes and Genes

Species

Benjamin Descours

Summary

Country: France

Publications

  1. pmc SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4(+) T-cells
    Benjamin Descours
    Institut de Genetique Humaine, CNRS UPR1142, Laboratoires de Virologie Moléculaire, Montpellier, France
    Retrovirology 9:87. 2012
  2. doi request reprint Phosphorylation of SAMHD1 by cyclin A2/CDK1 regulates its restriction activity toward HIV-1
    Alexandra Cribier
    Institut de Genetique Humaine, CNRS UPR1142, Laboratoires de Virologie Moléculaire, Montpellier 34000, France
    Cell Rep 3:1036-43. 2013

Collaborators

Detail Information

Publications2

  1. pmc SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4(+) T-cells
    Benjamin Descours
    Institut de Genetique Humaine, CNRS UPR1142, Laboratoires de Virologie Moléculaire, Montpellier, France
    Retrovirology 9:87. 2012
    ..Quiescent CD4+ T lymphocytes are highly refractory to HIV-1 infection due to a block at reverse transcription...
  2. doi request reprint Phosphorylation of SAMHD1 by cyclin A2/CDK1 regulates its restriction activity toward HIV-1
    Alexandra Cribier
    Institut de Genetique Humaine, CNRS UPR1142, Laboratoires de Virologie Moléculaire, Montpellier 34000, France
    Cell Rep 3:1036-43. 2013
    ..Our results uncover the phosphorylation of SAMHD1 at Thr592 by cyclin A2/CDK1 as a key regulatory mechanism of its antiviral activity...