Jacques Demotes-Mainard

Summary

Country: France

Publications

  1. ncbi Public-private partnership models in France and in Europe
    Jacques Demotes-Mainard
    Ministère de la Recherche, Paris, France
    Therapie 61:325-34, 313-23. 2006
  2. ncbi Towards a European Clinical Research Infrastructures Network: the ECRIN programme
    Jacques Demotes-Mainard
    centre d investigation clinique, INSERM CHU de Bordeaux, Hopital Cardiologique, Pessac, France
    Therapie 59:151-3. 2004
  3. ncbi European Clinical Research Infrastructures Network: promoting harmonisation and quality in European clinical research
    Jacques Demotes-Mainard
    ECRIN Co-ordination, CIC INSERM/CHU de Bordeaux, 33604 Pessac, France
    Lancet 365:107-8. 2005
  4. ncbi Clinical research infrastructures and networks in France: report on the French ECRIN workshop
    Jacques Demotes-Mainard
    Centre d Investigation Clinique INSERM CHU de Bordeaux, Bordeaux, France
    Therapie 60:183-99. 2005
  5. ncbi Avoiding drug-induced switching in patients with bipolar depression
    Chantal Henry
    Service Universitaire de Psychiatrie, CH Charles Perrens, Bordeaux, France
    Drug Saf 26:337-51. 2003
  6. ncbi Emotional hyper-reactivity as a fundamental mood characteristic of manic and mixed states
    Chantal Henry
    Service de Psychiatrie Adulte, Centre Hospitalier Charles Perrens, 121, rue de la Béchade, 33076 Bordeaux, France
    Eur Psychiatry 18:124-8. 2003
  7. ncbi Time-course of the expression of inflammatory cytokines and matrix metalloproteinases in the striatum and mesencephalon of mice injected with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, a dopaminergic neurotoxin
    Guillaume Hebert
    INSERM U 394 Neurobiologie Intégrative, Institut Francois Magendie, Bordeaux, France
    Neurosci Lett 349:191-5. 2003
  8. ncbi Common definition for categories of clinical research: a prerequisite for a survey on regulatory requirements by the European Clinical Research Infrastructures Network (ECRIN)
    Christine Kubiak
    Institut Thématique Santé Publique, Institut National de la Sante et de la Recherche Medicale INSERM, Paris, France
    Trials 10:95. 2009
  9. ncbi Emotional hyper-reactivity in normothymic bipolar patients
    Katia M'Bailara
    Departement de psychiatrie adulte, CHS Charles Perrens, Bordeaux, France
    Bipolar Disord 11:63-9. 2009
  10. ncbi Association of elevated glial expression of interleukin-1beta with improved survival in patients with glioblastomas multiforme
    Emmanuel Cuny
    , Bordeaux, France
    J Neurosurg 96:294-301. 2002

Collaborators

Detail Information

Publications18

  1. ncbi Public-private partnership models in France and in Europe
    Jacques Demotes-Mainard
    Ministère de la Recherche, Paris, France
    Therapie 61:325-34, 313-23. 2006
    ..As stated in the IMI strategic research agenda on efficacy, the quality of public infrastructures in Europe will be a key factor for its competitiveness and attractiveness for both academic and industry projects...
  2. ncbi Towards a European Clinical Research Infrastructures Network: the ECRIN programme
    Jacques Demotes-Mainard
    centre d investigation clinique, INSERM CHU de Bordeaux, Hopital Cardiologique, Pessac, France
    Therapie 59:151-3. 2004
    ....
  3. ncbi European Clinical Research Infrastructures Network: promoting harmonisation and quality in European clinical research
    Jacques Demotes-Mainard
    ECRIN Co-ordination, CIC INSERM/CHU de Bordeaux, 33604 Pessac, France
    Lancet 365:107-8. 2005
  4. ncbi Clinical research infrastructures and networks in France: report on the French ECRIN workshop
    Jacques Demotes-Mainard
    Centre d Investigation Clinique INSERM CHU de Bordeaux, Bordeaux, France
    Therapie 60:183-99. 2005
    ....
  5. ncbi Avoiding drug-induced switching in patients with bipolar depression
    Chantal Henry
    Service Universitaire de Psychiatrie, CH Charles Perrens, Bordeaux, France
    Drug Saf 26:337-51. 2003
    ....
  6. ncbi Emotional hyper-reactivity as a fundamental mood characteristic of manic and mixed states
    Chantal Henry
    Service de Psychiatrie Adulte, Centre Hospitalier Charles Perrens, 121, rue de la Béchade, 33076 Bordeaux, France
    Eur Psychiatry 18:124-8. 2003
    ..It is possible that the fundamental mood characteristic of mania is not tonality of mood (e.g. euphoric, irritable or depressed mood), but rather the intensity of emotions...
  7. ncbi Time-course of the expression of inflammatory cytokines and matrix metalloproteinases in the striatum and mesencephalon of mice injected with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, a dopaminergic neurotoxin
    Guillaume Hebert
    INSERM U 394 Neurobiologie Intégrative, Institut Francois Magendie, Bordeaux, France
    Neurosci Lett 349:191-5. 2003
    ....
  8. ncbi Common definition for categories of clinical research: a prerequisite for a survey on regulatory requirements by the European Clinical Research Infrastructures Network (ECRIN)
    Christine Kubiak
    Institut Thématique Santé Publique, Institut National de la Sante et de la Recherche Medicale INSERM, Paris, France
    Trials 10:95. 2009
    ..Thorough knowledge of the regulatory requirements is a challenging prerequisite for conducting multinational clinical studies in Europe given their complexity and heterogeneity in regulation and perception across the EU member states...
  9. ncbi Emotional hyper-reactivity in normothymic bipolar patients
    Katia M'Bailara
    Departement de psychiatrie adulte, CHS Charles Perrens, Bordeaux, France
    Bipolar Disord 11:63-9. 2009
    ....
  10. ncbi Association of elevated glial expression of interleukin-1beta with improved survival in patients with glioblastomas multiforme
    Emmanuel Cuny
    , Bordeaux, France
    J Neurosurg 96:294-301. 2002
    ..CONCLUSIONS: Taken together, these data indicate that the proinflammatory cytokine IL-1beta produced within GBM by glial-derived cells has a negative impact on tumor growth through a mechanism independent of iNOS induction...
  11. ncbi A role of IL-1 in MPTP-induced changes in striatal dopaminergic and serotoninergic transporter binding: clues from interleukin-1 type I receptor-deficient mice
    Guillaume Hebert
    INSERM U394, Neurobiologie Integrative, Institut Francois Magendie, rue Camille Saint Saens, 33077 Bordeaux Cedex, France
    Brain Res Mol Brain Res 136:267-70. 2005
    ..These data point to a possible role of IL-1RI in the early MPTP-induced structural or functional remodeling of the nigrostriatal dopamine system...
  12. ncbi Mood alterations during interferon-alfa therapy in patients with chronic hepatitis C: evidence for an overlap between manic/hypomanic and depressive symptoms
    Aymery Constant
    Department of Health Psychology EA 3662, University of Bordeaux 2, France
    J Clin Psychiatry 66:1050-7. 2005
    ..The impact of such findings on therapeutic management should be investigated...
  13. ncbi Developing a European framework for research on children's medicines: an examination of the proposed EU regulation on medicinal products for paediatric use
    Hannsjörg W Seyberth
    Philipps University, Marburg, Germany
    Pediatr Nephrol 20:1537-40. 2005
  14. ncbi Synthesis and initial results for MAO-B inhibition by new N-propargyl-3-pyrrol-1-ylindanamine derivatives, analogues of rasagiline
    Jean Guillon
    EA 2962-Pharmacochimie, UFR des Sciences Pharmaceutiques, , , 33076 Bordeaux Cedex, France
    J Enzyme Inhib Med Chem 18:147-53. 2003
    ..The new N-propargyl-3-pyrrol-1-ylindanamine derivatives were evaluated for their potential MAO-B inhibitor activity in an in vivo model of MPTP-induced Parkinsonism in mice with respect to the potent MAO-B inhibitor rasagiline...
  15. ncbi SSRIs, suicide and violent behavior: is there a need for a better definition of the depressive state?
    Chantal Henry
    Hôpital Charles Perrens, Bâtiment Lescure, 121 rue de la Bechade, 33076 Bordeaux Cedex, France
    Curr Drug Saf 1:59-62. 2006
    ..There is a clear need to develop an evidence-based approach to psychiatry aiming at delineating diagnostic categories predictive of the response to treatments...
  16. ncbi Cellular distribution of interleukin-1alpha-immunoreactivity after MPTP intoxication in mice
    Guillaume Hebert
    INSERM U394, Neurobiologie Integrative, Institut Francois Magendie, rue Camille Saint Saens, 33077 Bordeaux Cedex, France
    Brain Res Mol Brain Res 138:156-63. 2005
    ..In the striatum, IL-1alpha-ir was also detected in a non-astrocytic perivascular component, with a distribution similar to GAP-43-ir. IL-1alpha could thus directly or indirectly influence striatal reorganization after MPTP...
  17. ncbi Adjunctive antidepressant treatment for bipolar depression
    Chantal Henry
    N Engl J Med 357:614-5; author reply 615-6. 2007
  18. ncbi Olanzapine-induced mania in bipolar disorders
    Chantal Henry
    J Psychiatry Neurosci 27:200-1. 2002