Pascal Demoly

Summary

Country: France

Publications

  1. ncbi request reprint [ERAP, a pharmaco-epidemiologic survey on perennial allergic rhinitis in every day medical practice in France]
    Pascal Demoly
    Service des Maladies Respiratoires, INSERM U454 IFR3, Hopital Arnaud de Villeneuve, CHU de Montpellier, 34
    Presse Med 32:1066-73. 2003
  2. ncbi request reprint [Drug allergies: management and current aspects]
    P Demoly
    Clinique des Maladies Respiratoires, Hopital Arnaud de Villeneuve, Montpellier
    Presse Med 27:1406-11. 1998
  3. ncbi request reprint Managing asthma during pregnancy
    Pascal Demoly
    Exploration des Allergies Maladies Respiratoires, INSERM U454, Hopital Arnaud de Villeneuve, University Hospital of Montpellier, 34295 Montpellier Cedex 5, France
    Lancet 365:1212-3. 2005
  4. ncbi request reprint Anaphylaxis to antitetanus toxoid serum
    P Demoly
    Maladies Respiratoires, INSERM U454, Hopital Arnaud de Villeneuve, CHU de Montpellier, 34295 Montpellier Cedex 5, France
    Allergy 57:860-1. 2002
  5. ncbi request reprint Anaphylactic reactions--value of skin and provocation tests
    Pascal Demoly
    Exploration des Allergies, Maladies Respiratoires, INSERM U454, Hopital Arnaud de Villeneuve, University Hospital of Montpellier, 34295 Montpellier, France
    Toxicology 209:221-3. 2005
  6. ncbi request reprint Successful docetaxel tolerance induction
    D Messaad
    Maladies Respiratoires, INSERM U454, Hopital Arnaud de Villeneuve, CHU de Montpellier, 34295 Montpellier Cedex 5, France
    Allergy 58:1320-1. 2003
  7. ncbi request reprint Update on beta-lactam allergy diagnosis
    Pascal Demoly
    Exploration des Allergies, Maladies Respiratoires, INSERM U454 IFR3, Hopital Arnaud de Villeneuve, University Hospital of Montpellier, 34295 Montpellier Cedex 5, France
    Curr Allergy Asthma Rep 5:9-14. 2005
  8. ncbi request reprint Asthma therapy during pregnancy
    Pascal Demoly
    Exploration des Allergies Maladies Respiratoires INSERM U454, Hopital Arnaud de Villeneuve, Institut Universitaire de Recherche Clinique de Montpellier, University Hospital of Montpellier, 34295 Montpellier Cedex 5, France
    Expert Opin Pharmacother 4:1019-23. 2003
  9. doi request reprint Safety of intranasal corticosteroids in acute rhinosinusitis
    Pascal Demoly
    Clinical Department of Allergology, Maladies Respiratoires, INSERM U657, Hopital Arnaud de Villeneuve, University Hospital of Montpellier, Montpellier Cedex 5, France
    Am J Otolaryngol 29:403-13. 2008
  10. ncbi request reprint [Drug allergies and drug hypersensitivities]
    Pascal Demoly
    Unité d Exploration des Allergies, maladies respiratoires Inserm, Hopital Arnaud de Villeneuve, CHU de Montpellier, 34295 Montpellier Cedex 5
    Rev Prat 57:1326-30. 2007

Detail Information

Publications109 found, 100 shown here

  1. ncbi request reprint [ERAP, a pharmaco-epidemiologic survey on perennial allergic rhinitis in every day medical practice in France]
    Pascal Demoly
    Service des Maladies Respiratoires, INSERM U454 IFR3, Hopital Arnaud de Villeneuve, CHU de Montpellier, 34
    Presse Med 32:1066-73. 2003
    ..In order to gain knowledge on the management of perennial allergic rhinitis by the practitioners in France, a survey (Enquête épidémiologique sur la rhinite allergique per-annuelle en pratique quotidienne--ERAP) was developed...
  2. ncbi request reprint [Drug allergies: management and current aspects]
    P Demoly
    Clinique des Maladies Respiratoires, Hopital Arnaud de Villeneuve, Montpellier
    Presse Med 27:1406-11. 1998
    ..Allergic reactions are unpredictable reactions related to immunologic mechanism. Pseudoallergic reactions mimic allergic reactions but no drug-specific antibody or T cell proliferation can be demonstrated...
  3. ncbi request reprint Managing asthma during pregnancy
    Pascal Demoly
    Exploration des Allergies Maladies Respiratoires, INSERM U454, Hopital Arnaud de Villeneuve, University Hospital of Montpellier, 34295 Montpellier Cedex 5, France
    Lancet 365:1212-3. 2005
  4. ncbi request reprint Anaphylaxis to antitetanus toxoid serum
    P Demoly
    Maladies Respiratoires, INSERM U454, Hopital Arnaud de Villeneuve, CHU de Montpellier, 34295 Montpellier Cedex 5, France
    Allergy 57:860-1. 2002
  5. ncbi request reprint Anaphylactic reactions--value of skin and provocation tests
    Pascal Demoly
    Exploration des Allergies, Maladies Respiratoires, INSERM U454, Hopital Arnaud de Villeneuve, University Hospital of Montpellier, 34295 Montpellier, France
    Toxicology 209:221-3. 2005
    ..These tools are currently being evaluated by the European Network of Drug Allergy, under the aegis of the EAACI drug hypersensitivity group of interest...
  6. ncbi request reprint Successful docetaxel tolerance induction
    D Messaad
    Maladies Respiratoires, INSERM U454, Hopital Arnaud de Villeneuve, CHU de Montpellier, 34295 Montpellier Cedex 5, France
    Allergy 58:1320-1. 2003
  7. ncbi request reprint Update on beta-lactam allergy diagnosis
    Pascal Demoly
    Exploration des Allergies, Maladies Respiratoires, INSERM U454 IFR3, Hopital Arnaud de Villeneuve, University Hospital of Montpellier, 34295 Montpellier Cedex 5, France
    Curr Allergy Asthma Rep 5:9-14. 2005
    ..In this review, we describe the general guidelines for evaluating subjects in whom there is suspicion of allergic reactions to beta-lactams...
  8. ncbi request reprint Asthma therapy during pregnancy
    Pascal Demoly
    Exploration des Allergies Maladies Respiratoires INSERM U454, Hopital Arnaud de Villeneuve, Institut Universitaire de Recherche Clinique de Montpellier, University Hospital of Montpellier, 34295 Montpellier Cedex 5, France
    Expert Opin Pharmacother 4:1019-23. 2003
    ..Usually, there is at least one 'safe' drug from each major class used to control symptoms. We will review the current literature on this subject...
  9. doi request reprint Safety of intranasal corticosteroids in acute rhinosinusitis
    Pascal Demoly
    Clinical Department of Allergology, Maladies Respiratoires, INSERM U657, Hopital Arnaud de Villeneuve, University Hospital of Montpellier, Montpellier Cedex 5, France
    Am J Otolaryngol 29:403-13. 2008
    ....
  10. ncbi request reprint [Drug allergies and drug hypersensitivities]
    Pascal Demoly
    Unité d Exploration des Allergies, maladies respiratoires Inserm, Hopital Arnaud de Villeneuve, CHU de Montpellier, 34295 Montpellier Cedex 5
    Rev Prat 57:1326-30. 2007
    ..Biological tests are being evaluated. When properly performed in specialised centres, a firm diagnosis is often possible and safe alternative medication can be proposed...
  11. ncbi request reprint [Respiratory allergic disease genes]
    P Demoly
    Service des Maladies Respiratoires, Inserm U 454 IFR3, Hopital Arnaud de Villeneuve, CHU de Montpellier, 34295 Montpellier Cedex 5
    Rev Pneumol Clin 59:67-75. 2003
    ..Research will continue to define these genes more precisely or to recognize others and to apply this knowledge to therapeutic and diagnostic applications...
  12. ncbi request reprint Comparison of pharmacovigilance algorithms in drug hypersensitivity reactions
    Said Benahmed
    Exploration des Allergies Maladies Respiratoires, INSERM U454 IFR3, Hopital Arnaud de Villeneuve, CHU Montpellier, 34295 Montpellier Cedex 5, France
    Eur J Clin Pharmacol 61:537-41. 2005
    ..A firm diagnosis of drug hypersensitivity, because it may re-induce the reaction, is seldom confirmed. Causality assessment algorithms are therefore of interest...
  13. ncbi request reprint Classification and epidemiology of hypersensitivity drug reactions
    Pascal Demoly
    Allergy Department, Maladies Respiratoires and INSERM U454 IFR3, Hopital Arnaud de Villeneuve, University Hospital of Montpellier, 34295 Montpellier Cedex 5, France
    Immunol Allergy Clin North Am 24:345-56, v. 2004
    ..True epidemiologic data are limited, and most of the available information on the incidence, mortality, and socioeconomic impact should be discussed with caution...
  14. ncbi request reprint Treatment of allergic rhinitis during pregnancy
    Pascal Demoly
    Department of Respiratory Medicine, INSERM U454, Hospital Arnaud de Villeneuve, University Hospital of Montpellier, 34295 Cedex 5 Montpellier, France
    Drugs 63:1813-20. 2003
    ..There are no such data available for intra-nasal decongestants. Finally, pregnancy is not considered as a contraindication for the continuation of allergen specific immunotherapy...
  15. ncbi request reprint The place of spirometry in the diagnosis of asthma in those suffering from allergic rhinitis: a pilot study
    P Demoly
    Exploration des Allergies, Service des Maladies Respiratoires, INSERM U454 IFR3, Hopital Arnaud de Villeneuve, CHU de Montpellier, 34295 Montpellier Cedex 5, France
    Allergy 60:1089-90. 2005
  16. ncbi request reprint [Diagnosis of drug allergy]
    P Demoly
    Maladies Respiratoires, INSERM U454 IFR3, Hopital A de Villeneuve, CHU de Montpellier, France
    Rev Mal Respir 19:260-2. 2002
  17. ncbi request reprint The relation between asthma and allergic rhinitis
    Pascal Demoly
    Exploration des Allergies Maladies Respiratoires INSERM U454, Hopital Arnaud de Villeneuve, University Hospital of Montpellier, 34295 Montpellier Cedex 5, France
    Lancet 368:711-3. 2006
  18. ncbi request reprint [Identifying and understanding drug allergies]
    Pascal Demoly
    Inserm U 454 IFR3, Hopital Arnaud de Villeneuve, Avenue Gaston Giraud, 34295 Montpellier, France
    Med Sci (Paris) 19:327-36. 2003
    ....
  19. ncbi request reprint [Allergy to macrolides. 21 cases]
    P Demoly
    Maladies Respiratoires, Hôpital Amaud de Villeneuve, Montpellier
    Presse Med 29:294-8. 2000
    ..Allergic drug reactions to macrolides are extremely rare and there is little information in the literature concerning relevant diagnostic tests...
  20. ncbi request reprint [From allergic rhinitis to sinus diseases (sinusitis/nasal polyps): epidemiologic and experimental links]
    P Demoly
    Maladies Respiratoires, INSERM U454, IFR3, Hopital Arnaud de Villeneuve, Service d ORL, Hopital Gui de Chauliac, CHU de Montpellier
    Rev Mal Respir 17:925-30. 2000
    ..Because the diagnosis of allergic rhinitis provides useful therapeutic options, an appropriate evaluation for underlying allergies in indicated in any patient with chronic upper respiratory tract symptoms...
  21. ncbi request reprint [Allergy to macrolide antibiotics. Review of the literature]
    P Demoly
    INSERM U454 IFR3, Hôpital Amaud de Villeneuve, CHU de Montpellier
    Presse Med 29:321-6. 2000
    ..It would appear that macrolide allergies are unlikely to be class allergies. This is important as eviction advice could be limited to the single causal macrolide...
  22. ncbi request reprint Epidemiology of drug allergy
    P Demoly
    Maladies Respiratoires, INSERM U454 IFR3, Hopital Arnaud de Villeneuve, University Hospital of Montpellier, Montpellier, France
    Curr Opin Allergy Clin Immunol 1:305-10. 2001
    ..Therefore, there are few true epidemiological data, and most of those that are available, including incidence, mortality and socioeconomic impact data, should be interpreted with caution...
  23. ncbi request reprint [Genetics of asthma and atopy]
    P Demoly
    Maladies Respiratoires, INSERM U454, Hopital Arnaud de Villeneuve, CHU de Montpellier
    J Soc Biol 194:39-42. 2000
    ..Much of the information available today has been fragmentary and not always confirmed. Alleles at multiple loci are likely to be involved and the ultimate picture is most likely determined by many genetic and environmental factors...
  24. ncbi request reprint [Asthma and rhinitis medications: pregnancy precautions]
    P Demoly
    INSERM U454, IFR3, Hopital Arnaud de Villeneuve, CHU de Montpellier
    Presse Med 29:1625-9. 2000
    ..Indeed, it would be regrettable to be too prudent and deprive symptomatic patients of active treatments. Patients should be clearly informed of the benefits and risks of drug therapy...
  25. ncbi request reprint [Nasal allergy and asthma: one or two diseases?]
    Pascal Demoly
    Maladies Respiratoires, INSERM U454, IFR3, Hopital Arnaud de Villeneuve, CHU de Montpellier, 34295 Montpellier cedex 05
    Bull Acad Natl Med 189:1461-73. 2005
    ....
  26. ncbi request reprint Accuracy of a pharmacovigilance algorithm in diagnosing drug hypersensitivity reactions
    Said Benahmed
    Exploration des Allergies, Maladies Respiratoires, and Département d Information Médicale, Hopital Arnaud de Villeneuve, Montpellier, France
    Arch Intern Med 165:1500-5. 2005
    ..This study was performed to evaluate the diagnostic accuracy of a pharmacovigilance algorithm in patients with 1 or more histories suggestive of drug hypersensitivity...
  27. doi request reprint Impact of allergic rhinitis symptoms on quality of life in primary care
    Philippe Jean Bousquet
    University Hospital, CHU de Montpellier, Montpellier, France
    Int Arch Allergy Immunol 160:393-400. 2013
    ..Allergic rhinitis (AR) impairs quality of life (QoL), sleep and work. The Allergic Rhinitis and its Impact on Asthma (ARIA) classification is widely used, but the impact of the different symptoms on QoL is not clear...
  28. ncbi request reprint [Hypersensitivity to insulin]
    Djamel Messaad
    Exploration des Allergies, Maladies Respiratoires, INSERM U454 IFR3, Hopital Arnaud de Villeneuve, CHU, Montpellier
    Presse Med 33:631-8. 2004
    ..This frequency has decreased from 1 to 55% with non purified insulins and to 0.1 to 2% with newly generated insulins...
  29. ncbi request reprint Epidemiology of hypersensitivity drug reactions
    Eva Rebelo Gomes
    Allergy Department, INSERM U454 IFR3, Arnaud de Villeneuve Hospital, University Hospital of Montpellier, Montpellier, France
    Curr Opin Allergy Clin Immunol 5:309-16. 2005
    ..This review summarizes current knowledge on the incidence, prevalence, mortality and risk factors for these reactions in different populations...
  30. doi request reprint Budesonide/formoterol maintenance and reliever therapy versus conventional best practice
    Pascal Demoly
    University Hospital of Montpellier and INSERM U, Hopital Arnaud de Villeneuve, France
    Respir Med 103:1623-32. 2009
    ..29; P<0.01) while risk of remaining uncontrolled decreased (25% versus 29%, OR 0.81; P<0.01). Budesonide/formoterol maintenance and reliever therapy improves key aspects of asthma control versus physicians' choice of CBP...
  31. doi request reprint Safety of cefuroxime as an alternative in patients with a proven hypersensitivity to penicillins: a DAHD cohort survey
    Silvia Caimmi
    Exploration des Allergies, Clinique des Maladies Respiratoires and INSERM U657, Hopital Arnaud de Villeneuve, University Hospital of Montpellier, 371 Avenue du Doyen Gaston Giraud, Montpellier Cedex 5, France
    Int Arch Allergy Immunol 153:53-60. 2010
    ..In patients sensitized to beta-lactams, a safe beta-lactam alternative is often needed. The objective was to assess the safety of cefuroxime in patients with a proven beta-lactam allergy...
  32. doi request reprint How Can We Better Classify NSAID Hypersensitivity Reactions? - Validation from a Large Database
    Silvia Caimmi
    Allergy Department and INSERM U657, Hopital Arnaud de Villeneuve, University Hospital of Montpellier, Montpellier, France
    Int Arch Allergy Immunol 159:306-12. 2012
    ..It allows clinicians to identify patients at a high risk, based on the clinical history and clinical manifestations. Moreover, it is helpful for a better understanding and teaching of these reactions...
  33. ncbi request reprint Confirmation of the diagnosis of natural rubber latex allergy by the Basotest method
    Marie Laure Hemery
    Unit, Service des Maladies Respiratoires, Hopital Arnaud de Villeneuve, Montpellier, France
    Int Arch Allergy Immunol 136:53-7. 2005
    ..The aim of this study was to evaluate the performance (specificity and sensitivity) of Basotest in the diagnosis of natural rubber latex allergy...
  34. doi request reprint The Consolidated Standards of Reporting Trials (CONSORT) Statement applied to allergen-specific immunotherapy with inhalant allergens: a Global Allergy and Asthma European Network (GA(2)LEN) article
    Philippe J Bousquet
    Department of Respiratory Diseases, University Hospital of Montpellier, Montpellier, France
    J Allergy Clin Immunol 127:49-56, 56.e1-11. 2011
    ..Randomized trials provide evidence to inform treatment decisions. The Consolidated Standards of Reporting Trials (CONSORT) Statement is a set of recommendations for the reporting of trials...
  35. doi request reprint Important research questions in allergy and related diseases: nonallergic rhinitis: a GA2LEN paper
    J Bousquet
    University Hospital and INSERM, Montpellier, France
    Allergy 63:842-53. 2008
    ..It is likely that neuronal mechanisms, T cells, innate immunity and possibly auto-immune responses all play a role in NAR and may also contribute to the symptoms of allergic rhinitis...
  36. ncbi request reprint Clinical presentation and time course in hypersensitivity reactions to beta-lactams
    P J Bousquet
    Exploration des Allergies, Service des Maladies Respiratoires, Hopital Arnaud de Villeneuve, University Hospital of Montpellier INSERM U454 IFR3, Hopital Arnaud de Villeneuve, Montpellier, France
    Allergy 62:872-6. 2007
    ..beta-lactam hypersensitivity reactions are classified as immediate or nonimmediate. Diagnosis is usually based upon skin tests and provocation challenges...
  37. ncbi request reprint Drug provocation tests in patients with a history suggesting an immediate drug hypersensitivity reaction
    Djamel Messaad
    Hopital Arnaud de Villeneuve, Montpellier, France
    Ann Intern Med 140:1001-6. 2004
    ..Drug hypersensitivity reactions are common and can be life-threatening. Confirmation of the diagnosis should be rigorous and based on clinical history and a physical examination, possibly followed by skin tests and drug provocation tests...
  38. doi request reprint Update in drug allergy: novel drugs with novel reaction patterns
    Marta Rubio
    Allergy Department and INSERM U657, Hopital Arnaud de Villeneuve, University Hospital of Montpellier, Montpellier, France
    Curr Opin Allergy Clin Immunol 10:457-62. 2010
    ..This review summarizes current knowledge on the epidemiology, mechanisms, and clinical and in-vitro diagnosis of these reactions...
  39. ncbi request reprint [Allergen-specific immunotherapy or desensitization]
    Pascal Demoly
    Unité d Exploration des Allergies, Maladies Respiratoires, Hopital Arnaud de Villeneuve, CHU de Montpellier et Inserm U657, 34295 Montpellier Cedex 5, France
    Bull Acad Natl Med 193:1127-44; discussion 1144-5. 2009
    ..More information is also needed on patient selection, the treatment duration, and dosing schedules...
  40. doi request reprint Desloratadine for the treatment of cypress pollen-induced allergic rhinitis
    Pascal Demoly
    Allergy Department, INSERM U657, Maladies Respiratoires, Hopital Arnaud de Villeneuve, University Hospital of Montpellier, Montpellier, France
    Ann Allergy Asthma Immunol 103:260-6. 2009
    ..Few studies have been conducted to assess treatment options for patients with sensitivities to cypress pollens, important triggers of allergic rhinitis (AR) in the Mediterranean region...
  41. ncbi request reprint [Recommendations for the management of asthma]
    J Bousquet
    Service des Maladies Respiratoires, CHU Monptellier, INSERM U454, Hôpital Arnaud de Villeneuve 34 295 Montpellier
    Rev Prat 51:533-7. 2001
    ..These guidelines are applied in over 100 countries worldwide, and, in countries where they are applied, morbidity and mortality due to asthma have decreased...
  42. ncbi request reprint Drug hypersensitivity: epidemiology and risk factors
    L Guglielmi
    Maladies Respiratoires, INSERM U454 IFR3, Hopital Arnaud de Villeneuve, avenue du Doyen Gaston Giraud, 34295 Montpellier Cedex 5, France
    Curr Pharm Des 12:3309-12. 2006
    ..The chemical properties of the drug and the treatment regimen also influence the development of drug allergies...
  43. doi request reprint Development and implementation of guidelines in allergic rhinitis – an ARIA-GA2LEN paper
    Jean Bousquet
    University Hospital, Hopital Arnaud de Villeneuve, Montpellier Cedex 5, France
    Allergy 65:1212-21. 2010
    ..Guidelines must be updated as new management options become available or important new evidence emerges. Transparent reporting of guidelines facilitates understanding and acceptance, but implementation strategies need to be improved...
  44. ncbi request reprint National survey on the management of rhinopathies in asthma patients by French pulmonologists in everyday practice
    P Demoly
    Maladies Respiratoires, INSERM U454 IFR3, Hopital Arnaud de Villeneuve, University of Montpellier, France
    Allergy 58:233-8. 2003
    ..As part of this new report and prior to its diffusion, we investigated the management of rhinopathies in asthma patients by pulmonologists in their everyday practice...
  45. doi request reprint Unmet needs in severe chronic upper airway disease (SCUAD)
    Jean Bousquet
    University Hospital, Montpellier, France
    J Allergy Clin Immunol 124:428-33. 2009
    ..This document can also serve to optimize the pharmacoeconomic evaluation of SCUADs by means of comparison with mild chronic upper airway diseases...
  46. ncbi request reprint Drug hypersensitivities: definition, epidemiology and risk factors
    P Demoly
    Allergy Department, Maladies Respiratoires and INSERM U454, IFR3, Hopital Arnaud de Villeneuve, University Hospital of Montpellier, 34295 Montpellier Cedex 5, France
    Eur Ann Allergy Clin Immunol 37:202-6. 2005
    ..Future progress in genetics can help the identification of populations at risk for specific reactions. This review describes currently known data on incidence,prevalence, mor tality and risk factors of these reactions...
  47. ncbi request reprint Specific immunotherapy in rhinitis and asthma
    J Bousquet
    Service des Maladies Respiratoires, INSERM U454 Hĵpital Arnaud de Villeneuve, Montepelier, France
    Ann Allergy Asthma Immunol 87:38-42. 2001
    ....
  48. ncbi request reprint Prospects for a vaccine in allergic diseases and asthma
    J Bousquet
    Hopital Arnaud de Villeneuve, INSERM V454, Montpellier, France
    BioDrugs 13:61-75. 2000
    ..Nonspecific approaches include humanised anti-IgE antibodies,moderation of the T(H)2 cytokine network and antisense oligodeoxynucleotide therapy...
  49. ncbi request reprint Effects of carbamazepine and metabolites on IL-2, IL-5, IL-6, IL-10 and IFN-γ secretion in epileptic patients: the influence of co-medication
    Olivier Mathieu
    Département de Pharmacologie Médicale et Toxicologie, Centre Hospitalier Régional Universitaire de Montpellier, 191, Avenue Gaston Giraud, 34295 Montpellier Cedex 5, France
    Pharmacol Rep 63:86-94. 2011
    ....
  50. ncbi request reprint ERASM, a pharmacoepidemiologic survey on management of intermittent allergic rhinitis in every day general medical practice in France
    Pascal Demoly
    Service des Maladies Respiratoires, Hopital Arnaud de Villeneuve, CHU de Montpellier, France
    Allergy 57:546-54. 2002
    ..The actual management of intermittent allergic rhinitis is still little known about, despite the disease being very prevalent. We used a cross-sectional survey to address this issue in everyday general medical practice in France...
  51. ncbi request reprint Drug allergy diagnosis work up
    Pascal Demoly
    Maladies Respiratoires, INSERM U454, Hopital Arnaud de Villeneuve, CHU de Montpellier, F 34295 Montpellier, France
    Allergy 57:37-40. 2002
    ..These tools are currently being evaluated by the European Network of Drug Allergy, under the aegis of the EAACI drug hypersensitivity group of interest...
  52. ncbi request reprint Immunotherapy: clinical trials--optimal trial and clinical outcomes
    Philippe Jean Bousquet
    Clinique des Maladies Respiratoires, Hopital Arnaud de Villeneuve, Centre Hospitalier Universitaire, Montpellier, France
    Curr Opin Allergy Clin Immunol 7:561-6. 2007
    ..Although specific immunotherapy was introduced a century ago, very few trials meet the criteria for pivotal studies. The paper reviews the methods which should be used to investigate specific immunotherapy...
  53. doi request reprint Montelukast in guidelines and beyond
    Jean Bousquet
    Service des Maladies Respiratoires, Hopital Arnaud de Villeneuve, 371 Avenue Doyen Gaston Giraud, 34275 Montpellier, Cedex 5, France
    Adv Ther 26:575-87. 2009
    ..This review includes new studies that have not yet been considered in guidelines...
  54. doi request reprint Allergic rhinitis management pocket reference 2008
    J Bousquet
    Allergic Rhinitis and its Impact on Asthma, Service des Maladies Respiratoires, Hopital Arnaud de Villeneuve, 34295 Montpellier Cedex 5, France
    Allergy 63:990-6. 2008
    ..This document will be a major resource in this educational program...
  55. doi request reprint Physician and patient survey of allergic rhinitis in France: perceptions on prevalence, severity of symptoms, care management and specific immunotherapy
    P Demoly
    Unité d Exploration des Allergies, INSERM U657 Hôpital Arnaud de Villeneuve, Montpellier, France
    Allergy 63:1008-14. 2008
    ..A telephone survey of patients and physicians in France was carried out to understand better the real and perceived advantages and inconveniences of this therapeutic approach...
  56. ncbi request reprint ARIA (Allergic Rhinitis and Its Impact on Asthma) classification of allergic rhinitis severity in clinical practice in France
    P J Bousquet
    Exploration des Allergies, Maladies Respiratoires, INSERM U454 IFR3, Hopital Arnaud de Villeneuve, CHU de Montpellier, Montpellier, France
    Int Arch Allergy Immunol 143:163-9. 2007
    ..The Allergic Rhinitis and Its Impact on Asthma (ARIA) workshop proposes a classification of allergic rhinitis severity. It does not take into account impairment in quality of life and treatment should be adapted accordingly...
  57. ncbi request reprint Cysteinyl-leukotriene release test (CAST) in the diagnosis of immediate drug reactions
    B Lebel
    Maladies Respiratoires, INSERM U454 - IFR3, CHU de Montpellier, Montpellier Cedex, France
    Allergy 56:688-92. 2001
    ..The efficiency of both tests was low. CONCLUSION: Thus, in most cases, the in vitro Cys-LT test has little or no diagnostic utility and is not superior to histamine release...
  58. ncbi request reprint Relevance of the determination of serum-specific IgE antibodies in the diagnosis of immediate beta-lactam allergy
    C Fontaine
    Exploration des allergies Maladies Respiratoires and INSERM U454 IFR3, Hopital Arnaud de Villeneuve, University Hospital of Montpellier, Montpellier Cedex 5, France
    Allergy 62:47-52. 2007
    ..They can be explored by in vivo and/or in vitro tests. The measurement of serum-specific immunoglobulin E (IgE) presents several advantages: safety, simplicity, and availability to nonallergologist physicians...
  59. ncbi request reprint Validation of the classification of ARIA (allergic rhinitis and its impact on asthma)
    P Demoly
    Unité d Explorations des Allergies, Service des Maladies Respiratoires, INSERM, Hopital Arnaud de Villeneuve, Montpellier Cedex, France
    Allergy 58:672-5. 2003
    ..Allergic rhinitis is commonly divided into seasonal and perennial rhinitis. The recent Allergic Rhinitis and its Impact on Asthma (ARIA) workshop proposes to replace these terms by intermittent vs persistent rhinitis...
  60. ncbi request reprint Allergen-induced mediator release tests
    P Demoly
    Maladies Respiratoires INSERM U454, CHU de Montpellier, Cedex, France
    Allergy 58:553-8. 2003
    ..In this review, we will detail allergen-dependent histamine, tryptase, arachidonic acid metabolite, e.g. cysteinyl leukotrienes and 15-hydroxyeicosatetraenoic mediator release tests...
  61. doi request reprint [Respiratory allergies]
    Anca Mirela Chiriac
    Hopital Arnaud de Villeneuve, Département de Pneumologie et Addictologie, INSERM U657, 34295 Montpellier Cedex 5, France
    Presse Med 42:395-404. 2013
    ..In terms of route of administration, sublingual immunotherapy represents a good alternative to subcutaneous immunotherapy, considering its proven efficacy and better safety profile...
  62. pmc Assessment of disease control in allergic rhinitis
    Pascal Demoly
    Allergy Division, Pulmonary Department, INSERM U657 EA2415, Hopital Arnaud de Villeneuve, University Hospital of Montpellier, Montpellier, France
    Clin Transl Allergy 3:7. 2013
    ..We conclude that there is a need for research in which severity is compared with control in terms of their effects on patient management...
  63. pmc Comprehensive allergy work-up is mandatory in cystic fibrosis patients who report a history suggestive of drug allergy to beta-lactam antibiotics
    Silvia Caimmi
    Allergy Unit, Deépartement de Pneumologie et Addictologie, Hopital Arnaud de Villeneuve, University Hospital of Montpellier and Inserm U657, 37, avenue du Doyen Gaston Giraud, 34295, Montpellier Cedex 5, France
    Clin Transl Allergy 2:10. 2012
    ..abstract:..
  64. ncbi request reprint [Contribution of epidemiology to the prevention of drug allergies]
    Pascal Demoly
    Pneumologie et Addictologie, INSERM U657, Hopital Arnaud de Villeneuve, 371 Avenue du Doyen Gaston Giraud, 34295 Montpellier Cedex 5, France
    Bull Acad Natl Med 195:1335-42; discussion 1342-4. 2011
    ..This review examines the place of interventional epidemiology in the field of drug allergy, taking as examples both myorelaxant-induced anaphylaxis and abacavir-induced DRESS...
  65. ncbi request reprint Overexpression of the human glucocorticoid receptor alpha and beta isoforms inhibits AP-1 and NF-kappaB activities hormone independently
    Claire Gougat
    Institut National de la Santé et de la Recherche Médicale U454 IFR3 and Service des Maladies Respiratoires, CHU de Montpellier, 34295 Montpellier Cedex 5, France
    J Mol Med (Berl) 80:309-18. 2002
    ..This property was not shared by the closely related mineralocorticoid receptor. Our results suggest that overexpression of either GRalpha or GRbeta may have an anti-inflammatory effect...
  66. ncbi request reprint IFN-gamma-mediated inhibition of human IgE synthesis by IL-21 is associated with a polymorphism in the IL-21R gene
    Jerome Pene
    Institut National de la Sante et de la Recherche Medicale, Unite 454, Centre Hospitalier Universitaire St Eloi, Montpellier, France
    J Immunol 177:5006-13. 2006
    ....
  67. ncbi request reprint [Drug allergy and hypersensitivity. Risk factors]
    Pascal Demoly
    Exploration des Allergies Maladies Respiratoires, INSERM, Hopital Arnaud de Villeneuve, avenue du Doyen Gaston Giraud, 34295 Montpellier 5, France
    Bull Acad Natl Med 190:1733-42; discussion 1742-4. 2006
    ..An ongoing study by our group points to a role of polymorphisms within the IL-10 promoter and in the IL-4Ralpha gene in immediate reactions to beta-lactams...
  68. doi request reprint Spreading and impact of the World Health Organization's Allergic Rhinitis and its impact on asthma guidelines in everyday medical practice in France. Ernani survey
    P Demoly
    Allergy Department, University Hospital of Montpellier and Inserm U657, Hopital Arnaud de Villeneuve, 34295 Montpellier cedex 05, France
    Clin Exp Allergy 38:1803-7. 2008
    ..The aim of this study was to determine the spreading level of the WHO-ARIA (World Health Organization's Allergic Rhinitis and its Impact on Asthma) guidelines among the medical community and their influence on medical practices...
  69. doi request reprint Important questions in Allergy: 1--drug allergy/hypersensitivity
    P Demoly
    Exploration des Allergies Inserm U657, Hopital Arnaud de Villeneuve, University Hospital of Montpellier, Montpellier, France
    Allergy 63:616-9. 2008
  70. doi request reprint Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen)
    J Bousquet
    University Hospital and INSERM, Hopital Arnaud de Villeneuve, Montpellier, France
    Allergy 63:8-160. 2008
  71. ncbi request reprint [GA2LEN (Global Allergy and Asthma European Network)]
    J Bousquet
    CHU, Hopital Arnaud de Villeneuve, INSERM U780, Montpellier, France
    Rev Mal Respir 26:577-86. 2009
    ..The major achievements of GA2LEN are reported in this paper...
  72. ncbi request reprint Anaphylactic shock after oral intake and contact urticaria due to polyethylene glycols
    H B Co-Minh
    Dermatology Unit, St Eloi Hospital 80, avenue Augustin Fliche, 34295 Montpellier Cedex 5, France
    Allergy 62:92-3. 2007
    ..We reported an anaphylaxis after oral intake and contact urticaria due to polyethylene glycols...
  73. ncbi request reprint Selective hypersensitivity to pidolate
    N Raison-Peyron
    Maladies Respiratoires, INSERM U454 IFR3, Hôpital Arnaud de Villeneuve CHU Montpellier, France
    Allergy 57:53-4. 2002
  74. ncbi request reprint The diagnosis of asthma using a self-questionnaire in those suffering from allergic rhinitis: a pharmaco-epidemiological survey in everyday practice in France
    P Demoly
    Exploration des allergies Maladies Respiratoires and INSERM U454 IFR3, Hopital Arnaud de Villeneuve, University Hospital of Montpellier, Montpellier Cedex, France
    Allergy 61:699-704. 2006
    ....
  75. ncbi request reprint IL-10 promoter and IL4-Ralpha gene SNPs are associated with immediate beta-lactam allergy in atopic women
    L Guglielmi
    INSERM U454, CHU Arnaud de Villeneuve, Montpellier
    Allergy 61:921-7. 2006
    ..Allergic reactions to beta-lactam antibiotics represent the most frequent cause of immunological drug reactions...
  76. ncbi request reprint Variability in the clinical pattern of cutaneous side-effects of drugs with systemic symptoms: does a DRESS syndrome really exist?
    H Peyriere
    Department of Medical Pharmacology, University Hospital of Montpellier, Hopital Lapeyronie, 971 avenue du doyen Gaston Giraud, 34295 Montpellier Cedex 5, France
    Br J Dermatol 155:422-8. 2006
    ....
  77. ncbi request reprint Isolated urticaria to ondansetron and successful treatment with granisetron
    P J Bousquet
    Exploration des Allergies, Maladies Respiratoires, INSERM U454, Hopital Arnaud de Villeneuve, University Hospital of Montpellier, 34295 Montpellier Cedex 5, France
    Allergy 60:543-4. 2005
  78. ncbi request reprint Latex is not essential in a standardized skin prick test battery
    P J Bousquet
    University Hospital, Allergy, Montpellier, France
    Allergy 60:407-8. 2005
  79. ncbi request reprint Severe anaphylaxis to bee venom immunotherapy: efficacy of pretreatment and concurrent treatment with omalizumab
    C Galera
    Allergy and Respiratory Diseases Unit, Hopital Arnaud de Villeneuve, University Hospital of Montpellier, Montpellier, France
    J Investig Allergol Clin Immunol 19:225-9. 2009
    ..AntiIgE has provided a treatment option for patients with severe IgE-mediated allergic disease that is difficult to treat. This case suggests that omalizumab may be able to prevent anaphylaxis during immunotherapy...
  80. ncbi request reprint The accuracy of the diagnosis of suspected macrolide antibiotic hypersensitivity: results of a single-blinded trial
    S Benahmed
    Maladies Respiratoires, INSERM U454, Hopital Arnaud de Villeneuve, CHU de Montpellier, 34295 Montpellier Cedex 5, France
    Allergy 59:1130-3. 2004
  81. pmc Drug provocation tests: up-date and novel approaches
    Anca Mirela Chiriac
    Allergy Unit, Hopital Arnaud de Villeneuve, 371 Avenue du Doyen Giraud, Montpellier, 34295, France
    Allergy Asthma Clin Immunol 9:12. 2013
    ..Novel (or sometimes, simply renewed) approaches arise, awaiting to be either validated or refuted in larger studies in the future. Instead of covering the whole topic of DPTs, this paper will address these recent and challenging aspects...
  82. ncbi request reprint JLP5B9: new monoclonal antibody against polysialylated neural cell adhesion molecule is of value in phenotyping lung cancer
    M Del Rio
    CNRS UMR 9921, Centre de Recherche en Cancerologie, CRLC Val d Aurelle, Montpellier, France
    J Immunol Methods 233:21-31. 2000
    ..This mAb deserves further investigation to evaluate its potential as a tool for serodiagnosis of lung cancer...
  83. ncbi request reprint Long-term safety and efficacy of nevirapine tolerance induction
    D Messaad
    Maladies Respiratoires, Hopital Arnaud de Villeneuve, Montpellier University Hospital, France
    Clin Exp Allergy 32:733-5. 2002
    ..In non-serious cases, tolerance induction can be proposed...
  84. doi request reprint Efficacy of desloratadine in intermittent allergic rhinitis: a GA(2)LEN study
    J Bousquet
    Service des Maladies Respiratoires, Hopital Arnaud de Villeneuve, Montpellier, France
    Allergy 64:1516-23. 2009
    ..There is no placebo-controlled, randomized clinical trial on intermittent allergic rhinitis (IAR) to date. Desloratadine (DL) is recommended for the first-line treatment of seasonal and perennial allergic rhinitis...
  85. ncbi request reprint Immunotherapy with keyhole lampet hemocyanin-conjugated decapeptide vaccine in cypress pollen allergy
    P Demoly
    Maladies Respiratoires, Hopital Arnaud de Villeneuve, Montpellier, France
    Clin Exp Allergy 32:1071-6. 2002
    ..Cupressaceae pollen allergy is a world-wide pollinosis but immunotherapy has rarely been tested. Immunotherapy is usually allergen-specific but new forms may be targeted towards IgE...
  86. ncbi request reprint Prick tests to aeroallergens: is it possible simply to wipe the device between tests?
    V Piette
    Maladies Respiratoires, INSERM U454 IFR3, Hopital Arnaud de Villeneuve, CHU de Montpellier, France
    Allergy 57:940-2. 2002
    ....
  87. doi request reprint Clinical value of negative skin tests to iodinated contrast media
    S Caimmi
    Exploration des Allergies, Maladies Respiratoires and INSERM U657, Hopital Arnaud de Villeneuve, University Hospital of Montpellier, Montpellier Cedex 5, France
    Clin Exp Allergy 40:805-10. 2010
    ..Several studies have shown that skin tests are useful tools for the diagnosis of iodinated contrast medium (ICM) allergy, but the real number of false negative results is not known...
  88. ncbi request reprint [Skin testing with respiratory allergens: which techniques, which extracts, which battery?]
    V Piette
    Maladies Respiratoires, INSERM U454 IFR3, CHU de Montpellier, Montpellier, France
    Rev Mal Respir 19:529-31. 2002
  89. ncbi request reprint Oral challenges are needed in the diagnosis of beta-lactam hypersensitivity
    P J Bousquet
    Exploration des Allergies, Maladies Respiratoires and INSERM, Hopital Arnaud de Villeneuve, University Hospital of Montpellier, Montpellier Cedex 5, France
    Clin Exp Allergy 38:185-90. 2008
    ..Standardized European Network for Drug Allergy questionnaires, skin test and challenge procedures were followed...
  90. ncbi request reprint Diagnosis of neuromuscular blocking agent hypersensitivity reactions using cytofluorimetric analysis of basophils
    V Kvedariene
    INSERM U454 IFR3, Hopital Arnaud de Villeneuve, Montpellier Cedex, France
    Allergy 61:311-5. 2006
    ..Basophil activation based upon the expression of CD63 in the presence of specific allergens was found to be of importance for the diagnosis of IgE-mediated hypersensibility...
  91. doi request reprint Validation of a questionnaire for assessment of asthma patient knowledge and behaviour
    F Trebuchon
    University Hospital of Montpellier and Inserm U657, Montpellier, France
    Allergy 64:62-71. 2009
    ..However, no tool is available to assess change in patient knowledge and behaviour before and after completing an educational programme...
  92. ncbi request reprint Links between rhinitis and asthma
    J Bousquet
    Clinique des Maladies Respiratoires and INSERM U454, Hopital Arnaud de Villeneuve, CHU Montpellier, France
    Allergy 58:691-706. 2003
    ..Subjects with allergic rhinitis have an increased risk of developing asthma and may form a suitable population for secondary intervention to interrupt the 'allergic march'...
  93. ncbi request reprint Endoscopic surgical treatment of sinonasal polyposis-medium term outcomes (mean follow-up of 5 years)
    R Garrel
    Department of Otolaryngology, CHU Montpellier, France
    Rhinology 41:91-6. 2003
    ..Between 30 and 50% of patients with sinonasal polyposis (SNP) will require surgical treatment...
  94. ncbi request reprint Control and exacerbation of asthma: a survey of more than 3000 French physicians
    P Demoly
    Clinique des Maladies Respiratoires INSERM U454, Hopital Arnaud de Villeneuve, CHU Montpellier, Cedex, France
    Allergy 59:920-6. 2004
    ..Asthma control and prevention of exacerbations are primary objectives for asthma care. However there is a lack of universal definition of these notions which may therefore have a different meaning according to the physician's practice...
  95. ncbi request reprint [Specific immunotherapy for respiratory allergies. A modern treatment]
    M Ndiaye
    Service des Maladies Respiratoires, Exploration des Allergies, INSERM U454 IFR3, Hopital Arnaud de Villeneuve, CHU de Montpellier
    Presse Med 32:1508-16. 2003
    ..A greater use of the sublingual route, together with biological and clinical research will allow the widening of its indications...
  96. ncbi request reprint [Smoking habits, attitudes and knowledges of medical students of Medicine, Pharmacy and Odonto-Stomatology's Faculty of Dakar, Senegal]
    M Ndiaye
    Service des Maladies Respiratoires, Hopital Arnaud de Villeneuve, Montpellier, France
    Rev Mal Respir 20:701-9. 2003
    ..Smoking is a public health problem that does not spare the medical profession. We set out to determine the prevalence of smoking in medical students in Dakar and to assess their attitudes and knowledge in the face of this problem...
  97. ncbi request reprint [A revised nomenclature for allergy]
    P Meyer
    Service d explorations des allergies, Maladies Respiratoires, INSERM U454, CHU de Montpellier, Hopital Arnaud de Villeneuve, France
    Arch Pediatr 11:1131-4. 2004
    ..We will review here, as faithfully as possible, the distinct definitions and the right terms to use in allergy and in the other medical branches...
  98. ncbi request reprint Systemic reactions during skin tests with beta-lactams: a risk factor analysis
    Hoai Bich Co Minh
    J Allergy Clin Immunol 117:466-8. 2006
  99. ncbi request reprint Recent advances in the diagnosis of drug allergy
    Antonino Romano
    Allergy Unit of Integrated Complex Columbus, Catholic University of Sacred Heart, Rome, Italy
    Curr Opin Allergy Clin Immunol 7:299-303. 2007
    ..Immediate reactions occur within 1 h; nonimmediate ones occur after more than 1 h...
  100. ncbi request reprint Treating allergic rhinitis in pregnancy
    Vincent Piette
    Curr Allergy Asthma Rep 6:232-8. 2006
    ..There are no such data available for intranasal decongestants. Finally, pregnancy is not considered to be a contraindication for the continuation of immunotherapy...
  101. ncbi request reprint Hypersensitivity reactions to biological agents with special emphasis on tumor necrosis factor-alpha antagonists
    Paolo Campi
    Allergy and Clinical Immunology Unit, Nuovo Ospedale San Giovanni di Dio, Florence, Italy
    Curr Opin Allergy Clin Immunol 7:393-403. 2007
    ..Some of these reactions are frequent but without consequences for the patients. Others are less frequent but potentially life-threatening, and they include allergic reactions...