Doulaye Dembele

Summary

Country: France

Publications

  1. ncbi request reprint Fuzzy C-means method for clustering microarray data
    Doulaye Dembele
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS IMSERM ULP, BP 10142, 67404 Illkirch Cedex, France
    Bioinformatics 19:973-80. 2003
  2. pmc The App-Runx1 region is critical for birth defects and electrocardiographic dysfunctions observed in a Down syndrome mouse model
    Matthieu Raveau
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, Department of Translational Medicine and Neurogenetics, CNRS, INSERM, Universite de Strasbourg, UMR7104, UMR964, Illkirch, France
    PLoS Genet 8:e1002724. 2012
  3. doi request reprint β-Catenin activation synergizes with Pten loss and Myc overexpression in Notch-independent T-ALL
    Deepika Kaveri
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, Institut National de la Santé et de la Recherche Médicale U964, Centre National de la Recherche Scientifique UMR 7104, Universite de Strasbourg, Illkirch, France
    Blood 122:694-704. 2013
  4. doi request reprint Protracted abstinence from distinct drugs of abuse shows regulation of a common gene network
    Julie Le Merrer
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, INSERM and CNRS, Illkirch Graffenstaden, France
    Addict Biol 17:1-12. 2012
  5. pmc Tripartite motif 24 (Trim24/Tif1α) tumor suppressor protein is a novel negative regulator of interferon (IFN)/signal transducers and activators of transcription (STAT) signaling pathway acting through retinoic acid receptor α (Rarα) inhibition
    Johan Tisserand
    Department of Functional Genomics, Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS INSERM Universite Louis Pasteur, BP 10142, 67404 Illkirch Cedex, Communaute Urbaine de Strasbourg, France
    J Biol Chem 286:33369-79. 2011

Collaborators

  • Claus Nerlov
  • Yann Herault
  • Andrew J Sharp
  • Christelle Thibault
  • Deepika Kaveri
  • Julie Le Merrer
  • Matthieu Raveau
  • Johan Tisserand
  • Philippe Kastner
  • Susan Chan
  • Peggy Kirstetter
  • Emmanuel Darcq
  • Yoram Groner
  • Olivier Gardon
  • Jerome A J Becker
  • Arnaud Duchon
  • Jacques M Lignon
  • Dominique Filliol
  • Katia Befort
  • Valérie Nalesso
  • Brigitte L Kieffer
  • Veronique Brault
  • Konstantin Khetchoumian
  • Regine Losson
  • Pierre Chambon

Detail Information

Publications5

  1. ncbi request reprint Fuzzy C-means method for clustering microarray data
    Doulaye Dembele
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS IMSERM ULP, BP 10142, 67404 Illkirch Cedex, France
    Bioinformatics 19:973-80. 2003
    ..However, these methods do not provide information about the influence of a given gene for the overall shape of clusters. Here we apply a fuzzy partitioning method, Fuzzy C-means (FCM), to attribute cluster membership values to genes...
  2. pmc The App-Runx1 region is critical for birth defects and electrocardiographic dysfunctions observed in a Down syndrome mouse model
    Matthieu Raveau
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, Department of Translational Medicine and Neurogenetics, CNRS, INSERM, Universite de Strasbourg, UMR7104, UMR964, Illkirch, France
    PLoS Genet 8:e1002724. 2012
    ..These results might lead to new therapeutic strategies to improve the care of DS people...
  3. doi request reprint β-Catenin activation synergizes with Pten loss and Myc overexpression in Notch-independent T-ALL
    Deepika Kaveri
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, Institut National de la Santé et de la Recherche Médicale U964, Centre National de la Recherche Scientifique UMR 7104, Universite de Strasbourg, Illkirch, France
    Blood 122:694-704. 2013
    ....
  4. doi request reprint Protracted abstinence from distinct drugs of abuse shows regulation of a common gene network
    Julie Le Merrer
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, INSERM and CNRS, Illkirch Graffenstaden, France
    Addict Biol 17:1-12. 2012
    ..This transcriptional signature may represent a hallmark of drug abstinence and a unitary adaptive molecular mechanism in substance abuse disorders...
  5. pmc Tripartite motif 24 (Trim24/Tif1α) tumor suppressor protein is a novel negative regulator of interferon (IFN)/signal transducers and activators of transcription (STAT) signaling pathway acting through retinoic acid receptor α (Rarα) inhibition
    Johan Tisserand
    Department of Functional Genomics, Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS INSERM Universite Louis Pasteur, BP 10142, 67404 Illkirch Cedex, Communaute Urbaine de Strasbourg, France
    J Biol Chem 286:33369-79. 2011
    ..Altogether, these results identify Trim24 as a novel negative regulator of the IFN/STAT pathway and suggest that this repression through Rara inhibition may prevent liver cancer...