Research Topics
Species | Maurice DematteisSummaryCountry: France Publications
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Publications
Intermittent hypoxia induces early functional cardiovascular remodeling in miceMaurice Dematteis
Laboratoire HP2, Institut Jean Roget, Faculte de Medecine de Grenoble, 38042 Grenoble Cedex 09, France
Am J Respir Crit Care Med 177:227-35. 2008..Intermittent hypoxia, a hallmark of sleep apnea, is a major factor for hypertension and impaired vasoreactivity...
A simple procedure for measuring pharyngeal sensitivity: a contribution to the diagnosis of sleep apnoeaM Dematteis
Laboratoire HP2 INSERM ESPRI EA3745, Centre Hospitalier Universitaire, Grenoble Cedex, France
Thorax 60:418-26. 2005..The accuracy of a simple new procedure to measure pharyngeal sensitivity and to diagnose sleep disordered breathing (SDB) was investigated...
Cardiovascular consequences of sleep-disordered breathing: contribution of animal models to understanding the human diseaseMaurice Dematteis
HP2 Laboratory, INSERM ERI17, Universite Joseph Fourier, Grenoble, France
ILAR J 50:262-81. 2009..By combining clinical and experimental research, these models will contribute to the understanding of differential patient susceptibility and to the elaboration of prevention strategies and tailored treatments for sleep apnea patients...
Sleep deprivation, sleep apnea and cardiovascular diseasesPatrick Levy
INSERM U 1042, Hypoxia PathoPhysiology Laboratory, Joseph Fourier University, Grenoble, France
Front Biosci (Elite Ed) 4:2007-21. 2012..Whether treating sleep apnea enables the reversal of chronic cardiovascular and metabolic consequences of OSA, remains to be studied in adequately designed studies, particularly in comparison with usual treatment strategies...
The inflammatory preatherosclerotic remodeling induced by intermittent hypoxia is attenuated by RANTES/CCL5 inhibitionClaire Arnaud
Inserm U1042, Grenoble, France
Am J Respir Crit Care Med 184:724-31. 2011....
Obstructive sleep apnea and atherosclerosisPatrick Levy
HP2 Laboratory, INSERM ERI17, Joseph Fourier University, Grenoble, France
Prog Cardiovasc Dis 51:400-10. 2009..Further studies are needed to identify at-risk subjects prone to develop vascular changes because OSA treatment may either be initiated earlier or combined with specific drug treatments...
Inflammation contributes to the atherogenic role of intermittent hypoxia in apolipoprotein-E knock out miceClaire Arnaud
Inserm U1042, Grenoble, F 38042, France
Atherosclerosis 219:425-31. 2011..Our study aimed at examining their respective contribution to the proatherogenic role of IH in atherosclerosis-prone mice...
Obstructive sleep apnea, immuno-inflammation, and atherosclerosisClaire Arnaud
INSERM ERI17, Grenoble, 38043, France
Semin Immunopathol 31:113-25. 2009....
Intermittent hypoxia and sleep-disordered breathing: current concepts and perspectivesP Levy
Pathophysiology Laboratory, Grenoble University, Grenoble, France
Eur Respir J 32:1082-95. 2008..Overall, chronic intermittent hypoxia appears to have specific genomic effects that differ notably from continuous hypoxia. Further research is required to fully elucidate the molecular and cellular mechanisms...
Charcot-Marie-Tooth disease and sleep apnoea syndrome: a family studyM Dematteis
, University Hospital, Grenoble, France
Lancet 357:267-72. 2001..Upper airway dysfunction, previously described in the CMT2C subtype, might be a clinical expression of the CMT1A subtype, to which familial susceptibility could predispose...
An adaptive detector of genioglossus EMG reflex using Berkner transform for time latency measurement in OSA pathophysiological studiesPierre Yves Gumery
Laboratoire Techniques de l Imagerie, de la Modélisation et de la Cognition, UMR CNRS 5525, Joseph Fourier University, 38706 Grenoble, France
IEEE Trans Biomed Eng 52:1382-9. 2005..These physiological findings may partly explain why the upper airway protective reflex occurring when a negative pressure is applied to the upper airway is ineffective in OSA patients, leading to pharyngeal collapse...
