Pierre Delobel

Summary

Country: France

Publications

  1. pmc Genotypic prediction of HIV-1 subtype D tropism
    Stéphanie Raymond
    INSERM, U1043, Toulouse, F 31300 France
    Retrovirology 8:56. 2011
  2. pmc Minor HIV-1 variants with the K103N resistance mutation during intermittent efavirenz-containing antiretroviral therapy and virological failure
    Pierre Delobel
    Service des Maladies Infectieuses et Tropicales, Hopital Purpan, Toulouse, France
    PLoS ONE 6:e21655. 2011
  3. doi request reprint CXCR4-using viruses in plasma and peripheral blood mononuclear cells during primary HIV-1 infection and impact on disease progression
    Stéphanie Raymond
    INSERM, U563 Toulouse, Toulouse, France
    AIDS 24:2305-12. 2010
  4. doi request reprint Frequency of CXCR4-using viruses in primary HIV-1 infections using ultra-deep pyrosequencing
    Stéphanie Raymond
    INSERM U, Toulouse, France
    AIDS 25:1668-70. 2011
  5. ncbi request reprint Characterization of CXCR4-using HIV-1 during primary infection by ultra-deep pyrosequencing
    Stéphanie Raymond
    INSERM, UMR1043, Toulouse, France
    J Antimicrob Chemother 68:2875-81. 2013
  6. doi request reprint Development and performance of a new recombinant virus phenotypic entry assay to determine HIV-1 coreceptor usage
    Stéphanie Raymond
    INSERM, U563, Toulouse, F 31300, France
    J Clin Virol 47:126-30. 2010
  7. pmc Altered CD4+ T cell homing to the gut impairs mucosal immune reconstitution in treated HIV-infected individuals
    Maud Mavigner
    INSERM, UMR1043, Toulouse, France
    J Clin Invest 122:62-9. 2012
  8. doi request reprint Pathogenesis of the immune reconstitution inflammatory syndrome affecting the central nervous system in patients infected with HIV
    Guillaume Martin-Blondel
    Infectious and Tropical Diseases Department, Toulouse University Hospital, Toulouse, F 31300, France
    Brain 134:928-46. 2011
  9. doi request reprint Maraviroc intensification of stable antiviral therapy in HIV-1-infected patients with poor immune restoration: MARIMUNO-ANRS 145 study
    Lise Cuzin
    Infectious Diseases Department, University Hospital, Toulouse, France
    J Acquir Immune Defic Syndr 61:557-64. 2012
  10. doi request reprint Phenotyping methods for determining HIV tropism and applications in clinical settings
    Stéphanie Raymond
    INSERM, U1043, Toulouse, F 31300 France
    Curr Opin HIV AIDS 7:463-9. 2012

Collaborators

Detail Information

Publications11

  1. pmc Genotypic prediction of HIV-1 subtype D tropism
    Stéphanie Raymond
    INSERM, U1043, Toulouse, F 31300 France
    Retrovirology 8:56. 2011
    ..Recent studies indicate that the genotypic algorithms used routinely to assess HIV-1 tropism may lack accuracy for non-B subtypes. Little is known about the genotypic determinants of HIV-1 subtype D tropism...
  2. pmc Minor HIV-1 variants with the K103N resistance mutation during intermittent efavirenz-containing antiretroviral therapy and virological failure
    Pierre Delobel
    Service des Maladies Infectieuses et Tropicales, Hopital Purpan, Toulouse, France
    PLoS ONE 6:e21655. 2011
    ..04). Thus ultrasensitive methods could prove more useful than direct sequencing for predicting treatment failure in some patients. However the presence of minor NNRTI-resistant viruses need not always result in virological escape...
  3. doi request reprint CXCR4-using viruses in plasma and peripheral blood mononuclear cells during primary HIV-1 infection and impact on disease progression
    Stéphanie Raymond
    INSERM, U563 Toulouse, Toulouse, France
    AIDS 24:2305-12. 2010
    ..Thus, we determined HIV-1 tropism in both these compartments during primary infection and evaluated the impact of CXCR4-using viruses on disease progression...
  4. doi request reprint Frequency of CXCR4-using viruses in primary HIV-1 infections using ultra-deep pyrosequencing
    Stéphanie Raymond
    INSERM U, Toulouse, France
    AIDS 25:1668-70. 2011
    ..75) and in 14% using the combined 11/25 and net charge rule. The phenotypic assay identified 9% of CXCR4-using viruses. This confirms that R5 viruses are predominant in primary HIV-1 infections...
  5. ncbi request reprint Characterization of CXCR4-using HIV-1 during primary infection by ultra-deep pyrosequencing
    Stéphanie Raymond
    INSERM, UMR1043, Toulouse, France
    J Antimicrob Chemother 68:2875-81. 2013
    ..Phenotypic assays provide only qualitative results: the presence or absence of CXCR4-using viruses. We have therefore used ultra-deep pyrosequencing (UDS) to determine the frequency of CXCR4-using viruses among HIV-1 quasispecies...
  6. doi request reprint Development and performance of a new recombinant virus phenotypic entry assay to determine HIV-1 coreceptor usage
    Stéphanie Raymond
    INSERM, U563, Toulouse, F 31300, France
    J Clin Virol 47:126-30. 2010
    ..Few phenotypic assays are available, with few data on their concordance, and none has been designed to determine tropism from cell-associated HIV-1 DNA...
  7. pmc Altered CD4+ T cell homing to the gut impairs mucosal immune reconstitution in treated HIV-infected individuals
    Maud Mavigner
    INSERM, UMR1043, Toulouse, France
    J Clin Invest 122:62-9. 2012
    ..Our results thus describe alterations in CD4+ T cell homing to the gut that could prevent efficient mucosal immune reconstitution in HIV-infected individuals despite effective cART...
  8. doi request reprint Pathogenesis of the immune reconstitution inflammatory syndrome affecting the central nervous system in patients infected with HIV
    Guillaume Martin-Blondel
    Infectious and Tropical Diseases Department, Toulouse University Hospital, Toulouse, F 31300, France
    Brain 134:928-46. 2011
    ..Our current perception of this neuroinflammatory disease supports therapeutic strategies aimed at modulating immune aggression without dampening the life-saving restoration of the immune response...
  9. doi request reprint Maraviroc intensification of stable antiviral therapy in HIV-1-infected patients with poor immune restoration: MARIMUNO-ANRS 145 study
    Lise Cuzin
    Infectious Diseases Department, University Hospital, Toulouse, France
    J Acquir Immune Defic Syndr 61:557-64. 2012
    ..To address the ability of a 24-week Maraviroc (MVC) intensification of a stable antiretroviral therapy (cART) to significantly increase the CD4 cell count slope...
  10. doi request reprint Phenotyping methods for determining HIV tropism and applications in clinical settings
    Stéphanie Raymond
    INSERM, U1043, Toulouse, F 31300 France
    Curr Opin HIV AIDS 7:463-9. 2012
    ..Hence, several methods have been developed for assessing HIV-1 tropism in patients who are candidates for CCR5 antagonists. This article reviews current data on phenotypic assays of tropism...
  11. pmc HIV-1 residual viremia correlates with persistent T-cell activation in poor immunological responders to combination antiretroviral therapy
    Maud Mavigner
    INSERM, U563, Toulouse, France
    PLoS ONE 4:e7658. 2009
    ....