Jacques Delarue

Summary

Country: France

Publications

  1. ncbi request reprint N-3 long chain polyunsaturated fatty acids: a nutritional tool to prevent insulin resistance associated to type 2 diabetes and obesity?
    Jacques Delarue
    EA 948 Oxylipides, Faculte de Medecine, 29200 Brest, France
    Reprod Nutr Dev 44:289-99. 2004
  2. ncbi request reprint Fish-oil supplementation reduces stimulation of plasma glucose fluxes during exercise in untrained males
    Jacques Delarue
    Laboratoire Régional de Nutrition Humaine and EA 948, Médecine 4 Nutrition, CHU Cavale Blanche, F 29200 Brest, France
    Br J Nutr 90:777-86. 2003
  3. ncbi request reprint Interaction of fish oil and a glucocorticoid on metabolic responses to an oral glucose load in healthy human subjects
    Jacques Delarue
    Equipe d Accueil 948 Oxylipids, Laboratoire Régional de Nutrition Humanaine, Faculté de Médecine de Brest and CHU, F 29 200 Brest, France
    Br J Nutr 95:267-72. 2006
  4. ncbi request reprint Free fatty acids and insulin resistance
    Jacques Delarue
    Laboratoire Régional de Nutrition Humaine and EA 948, CHU de Brest et Université de Bretagne Occidentale, Brest, France
    Curr Opin Clin Nutr Metab Care 10:142-8. 2007
  5. ncbi request reprint Fish oil attenuates adrenergic overactivity without altering glucose metabolism during an oral glucose load in haemodialysis patients
    Jacques Delarue
    Laboratoire Régional de Nutrition Humaine and EA 948 Oxylipides, CHU Cavale Blanche, Brest, France
    Br J Nutr 99:1041-7. 2008
  6. ncbi request reprint Long-chain n-3 polyunsaturated fatty acids dissociate phosphorylation of Akt from phosphatidylinositol 3'-kinase activity in rats
    Christelle Le Foll
    Equipe d Accueil Oxylipides, Faculte de Medecine, Brest, France
    Am J Physiol Endocrinol Metab 292:E1223-30. 2007
  7. ncbi request reprint Adipose tissue compensates for defect of phosphatidylinositol 3'-kinase induced in liver and muscle by dietary fish oil in fed rats
    Charlotte Corporeau
    Equipe d Accueil 948 Oxylipides, Faculte de Medecine, Brest Cedex 3, France
    Am J Physiol Endocrinol Metab 290:E78-E86. 2006
  8. doi request reprint Polyunsaturated fatty acids inhibit PI3K activity in a yeast-based model system
    Elodie Couplan
    INSERM U, Brest, France
    Biotechnol J 4:1190-7. 2009
  9. doi request reprint Interaction of low dose of fish oil and glucocorticoids on insulin sensitivity and lipolysis in healthy humans: A randomized controlled study
    Jacques Delarue
    Department of Nutritional Sciences and Laboratory of Human Nutrition, University Hospital of Brest, Brest University, Brest, France
    Mol Nutr Food Res 60:886-96. 2016
  10. doi request reprint Laparoscopic sleeve gastrectomy versus laparoscopic mini gastric bypass: One year outcomes
    Gaby Kansou
    Department of General, Digestive and Metabolic Surgery, La Cavale Blanche University Hospital, Boulevard Tanguy Prigent, 29200 Brest, France
    Int J Surg 33:18-22. 2016

Collaborators

  • Richard Cohen
  • Daniele Lucas
  • M Taouis
  • Mette M Berger
  • R L Chiolero
  • Christelle Le Foll
  • Charlotte Corporeau
  • Gaby Kansou
  • Elodie Couplan
  • Jean Pascal Bergé
  • Jean Paul Gouygou
  • Stéphane Villet
  • Bogdan Badic
  • Jérémie Thereaux
  • Jean Pierre Bail
  • David Lechaux
  • Sophie Guillerm
  • Morgan Le Gall
  • Marc Blondel
  • Marie Le Cann
  • Valérie Le Guen
  • Marie Christine Cayeux R N
  • Marc D Bollmann
  • Jean Pierre Revelly

Detail Information

Publications12

  1. ncbi request reprint N-3 long chain polyunsaturated fatty acids: a nutritional tool to prevent insulin resistance associated to type 2 diabetes and obesity?
    Jacques Delarue
    EA 948 Oxylipides, Faculte de Medecine, 29200 Brest, France
    Reprod Nutr Dev 44:289-99. 2004
    ..These effects are encouraging in the perspective of prevention of insulin resistance but further clinical and basic studies must be designed to confirm and complete our knowledge in this field...
  2. ncbi request reprint Fish-oil supplementation reduces stimulation of plasma glucose fluxes during exercise in untrained males
    Jacques Delarue
    Laboratoire Régional de Nutrition Humaine and EA 948, Médecine 4 Nutrition, CHU Cavale Blanche, F 29200 Brest, France
    Br J Nutr 90:777-86. 2003
    ..72) micromol/kg per min). It is concluded that fish oil reduced the Rd glucose by 26 % by reducing glucose metabolic clearance rate, possibly by facilitating fat oxidation, and reduced HGP by 21%, possibly by a feedback mechanism...
  3. ncbi request reprint Interaction of fish oil and a glucocorticoid on metabolic responses to an oral glucose load in healthy human subjects
    Jacques Delarue
    Equipe d Accueil 948 Oxylipids, Laboratoire Régional de Nutrition Humanaine, Faculté de Médecine de Brest and CHU, F 29 200 Brest, France
    Br J Nutr 95:267-72. 2006
    ..Following fish oil supplementation, plasma glucose fluxes and substrate oxidation were maintained despite a 17 % reduction (P<0.05) in the area under the curve of plasma insulin response, suggesting an insulin-sensitizing effect...
  4. ncbi request reprint Free fatty acids and insulin resistance
    Jacques Delarue
    Laboratoire Régional de Nutrition Humaine and EA 948, CHU de Brest et Université de Bretagne Occidentale, Brest, France
    Curr Opin Clin Nutr Metab Care 10:142-8. 2007
    ..However, other mechanisms are now described to explain the molecular basis of insulin resistance...
  5. ncbi request reprint Fish oil attenuates adrenergic overactivity without altering glucose metabolism during an oral glucose load in haemodialysis patients
    Jacques Delarue
    Laboratoire Régional de Nutrition Humaine and EA 948 Oxylipides, CHU Cavale Blanche, Brest, France
    Br J Nutr 99:1041-7. 2008
    ..These data show that in haemodialysis patients, fish oil attenuates adrenal overactivity induced by oral glucose but does not modulate whole-body glucose metabolism and insulin sensitivity...
  6. ncbi request reprint Long-chain n-3 polyunsaturated fatty acids dissociate phosphorylation of Akt from phosphatidylinositol 3'-kinase activity in rats
    Christelle Le Foll
    Equipe d Accueil Oxylipides, Faculte de Medecine, Brest, France
    Am J Physiol Endocrinol Metab 292:E1223-30. 2007
    ..The inability of LC n-3 PUFA to prevent insulin resistance by dexamethasone could result from the lack of such a dissociation...
  7. ncbi request reprint Adipose tissue compensates for defect of phosphatidylinositol 3'-kinase induced in liver and muscle by dietary fish oil in fed rats
    Charlotte Corporeau
    Equipe d Accueil 948 Oxylipides, Faculte de Medecine, Brest Cedex 3, France
    Am J Physiol Endocrinol Metab 290:E78-E86. 2006
    ..The maintenance of whole body glucose homeostasis suggests an important role of adipose tissue for control of glucose homeostasis...
  8. doi request reprint Polyunsaturated fatty acids inhibit PI3K activity in a yeast-based model system
    Elodie Couplan
    INSERM U, Brest, France
    Biotechnol J 4:1190-7. 2009
    ..These results are particularly promising given the abundance of active PUFA in marine foodstuffs and especially fish oils...
  9. doi request reprint Interaction of low dose of fish oil and glucocorticoids on insulin sensitivity and lipolysis in healthy humans: A randomized controlled study
    Jacques Delarue
    Department of Nutritional Sciences and Laboratory of Human Nutrition, University Hospital of Brest, Brest University, Brest, France
    Mol Nutr Food Res 60:886-96. 2016
    ..This study examined the interaction of fish oil (FO) with dexamethasone on glucose and lipid metabolisms in healthy subjects...
  10. doi request reprint Laparoscopic sleeve gastrectomy versus laparoscopic mini gastric bypass: One year outcomes
    Gaby Kansou
    Department of General, Digestive and Metabolic Surgery, La Cavale Blanche University Hospital, Boulevard Tanguy Prigent, 29200 Brest, France
    Int J Surg 33:18-22. 2016
    ..However, studies comparing LSG and LMGB are scarce...
  11. ncbi request reprint N-3 polyunsaturated fatty acids prevent the defect of insulin receptor signaling in muscle
    Mohammed Taouis
    Station de Recherches Avicoles, Institut National de la Recherche Agronomique Centre de Tours, 37380 Nouzilly, France
    Am J Physiol Endocrinol Metab 282:E664-71. 2002
    ..A high-fat diet (n-3) partially altered the expression of p85 but not that of GLUT-4 and leptin mRNAs in adipose tissue...
  12. ncbi request reprint Negative impact of hypocaloric feeding and energy balance on clinical outcome in ICU patients
    Stéphane Villet
    Anesthésiologie, Centre Hospitalier Universitaire Vaudois CHUV, 1011 Lausanne, Switzerland
    Clin Nutr 24:502-9. 2005
    ..Critically ill patients with complicated evolution are frequently hypermetabolic, catabolic, and at risk of underfeeding. The study aimed at assessing the relationship between energy balance and outcome in critically ill patients...