Arlette Darfeuille-Michaud

Summary

Country: France

Publications

  1. ncbi request reprint Presence of adherent Escherichia coli strains in ileal mucosa of patients with Crohn's disease
    A Darfeuille-Michaud
    Laboratoire de Bacteriologie, Faculte de Pharmacie, Clermont Ferrand Cedex, France
    Gastroenterology 115:1405-13. 1998
  2. ncbi request reprint Adherent-invasive Escherichia coli: a putative new E. coli pathotype associated with Crohn's disease
    Arlette Darfeuille-Michaud
    Pathogenie Bacterienne Intestinale, Institut Universitaire de Technologie et Faculté de Pharmacie, Universite d Auvergne, Clermont Ferrand, France
    Int J Med Microbiol 292:185-93. 2002
  3. ncbi request reprint Adherent-invasive Escherichia coli isolated from Crohn's disease patients induce granulomas in vitro
    Sonia Meconi
    Department Molecular Mechanisms of Mycobacterial Infections, IPBS, CNRS UMR5089, Toulouse 31077, France
    Cell Microbiol 9:1252-61. 2007
  4. ncbi request reprint Abnormalities in the handling of intracellular bacteria in Crohn's disease: a link between infectious etiology and host genetic susceptibility
    Anne Lise Glasser
    Pathogenie Bacterienne Intestinale, Universite d Auvergne, JE 2526, USC INRA 2018, Clermont Ferrand, France
    Arch Immunol Ther Exp (Warsz) 56:237-44. 2008
  5. pmc Abnormally expressed ER stress response chaperone Gp96 in CD favours adherent-invasive Escherichia coli invasion
    Nathalie Rolhion
    Pathogenie Bacterienne Intestinale, Universite d Auvergne, CBRV, 28 Place Henri Dunant, Clermont Ferrand, France
    Gut 59:1355-62. 2010
  6. pmc Role of meprins to protect ileal mucosa of Crohn's disease patients from colonization by adherent-invasive E. coli
    Emilie Vazeille
    Clermont Universite, JE2526 Université d Auvergne, Clermont Ferrand, France
    PLoS ONE 6:e21199. 2011
  7. pmc Biofilm formation as a novel phenotypic feature of adherent-invasive Escherichia coli (AIEC)
    Margarita Martinez-Medina
    Laboratory of Molecular Microbiology, Biology Department, University of Girona, Spain
    BMC Microbiol 9:202. 2009
  8. pmc The oxidoreductase DsbA plays a key role in the ability of the Crohn's disease-associated adherent-invasive Escherichia coli strain LF82 to resist macrophage killing
    Marie Agnès Bringer
    Pathogenie Bacterienne Intestinale, université Clermont I, USC INRA 2018, F 63000 Clermont Fd, France
    J Bacteriol 189:4860-71. 2007
  9. ncbi request reprint High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn's disease
    Arlette Darfeuille-Michaud
    Pathogenie Bacterienne Intestinale, Laboratoire de Bacteriologie, Universite d Auvergne, Clermont Ferrand, France
    Gastroenterology 127:412-21. 2004
  10. doi request reprint Western diet induces dysbiosis with increased E coli in CEABAC10 mice, alters host barrier function favouring AIEC colonisation
    Margarita Martinez-Medina
    Clermont Universite, Microbe intestin inflammation et Susceptibilité de l Hôte, UMR1071 Inserm Université d Auvergne M2iSH, Clermont Ferrand, France
    Gut 63:116-24. 2014

Collaborators

Detail Information

Publications50

  1. ncbi request reprint Presence of adherent Escherichia coli strains in ileal mucosa of patients with Crohn's disease
    A Darfeuille-Michaud
    Laboratoire de Bacteriologie, Faculte de Pharmacie, Clermont Ferrand Cedex, France
    Gastroenterology 115:1405-13. 1998
    ..This study was designed to look for the presence of virulent Escherichia coli strains associated with the ileal mucosa of patients with Crohn's disease...
  2. ncbi request reprint Adherent-invasive Escherichia coli: a putative new E. coli pathotype associated with Crohn's disease
    Arlette Darfeuille-Michaud
    Pathogenie Bacterienne Intestinale, Institut Universitaire de Technologie et Faculté de Pharmacie, Universite d Auvergne, Clermont Ferrand, France
    Int J Med Microbiol 292:185-93. 2002
    ....
  3. ncbi request reprint Adherent-invasive Escherichia coli isolated from Crohn's disease patients induce granulomas in vitro
    Sonia Meconi
    Department Molecular Mechanisms of Mycobacterial Infections, IPBS, CNRS UMR5089, Toulouse 31077, France
    Cell Microbiol 9:1252-61. 2007
    ..Although the cell aggregates not completely mimic natural CD-associated granulomas, they are very similar to early stages of epithelioid granulomas...
  4. ncbi request reprint Abnormalities in the handling of intracellular bacteria in Crohn's disease: a link between infectious etiology and host genetic susceptibility
    Anne Lise Glasser
    Pathogenie Bacterienne Intestinale, Universite d Auvergne, JE 2526, USC INRA 2018, Clermont Ferrand, France
    Arch Immunol Ther Exp (Warsz) 56:237-44. 2008
    ....
  5. pmc Abnormally expressed ER stress response chaperone Gp96 in CD favours adherent-invasive Escherichia coli invasion
    Nathalie Rolhion
    Pathogenie Bacterienne Intestinale, Universite d Auvergne, CBRV, 28 Place Henri Dunant, Clermont Ferrand, France
    Gut 59:1355-62. 2010
    ..The expression of the ER-localised stress response protein Gp96 in patients with CD and its biological role with regards to the ability of AIEC to invade intestinal epithelial cells were analysed...
  6. pmc Role of meprins to protect ileal mucosa of Crohn's disease patients from colonization by adherent-invasive E. coli
    Emilie Vazeille
    Clermont Universite, JE2526 Université d Auvergne, Clermont Ferrand, France
    PLoS ONE 6:e21199. 2011
    ..Thus, decreased levels of protective meprins as observed in CD patients may contribute to increased AIEC colonization...
  7. pmc Biofilm formation as a novel phenotypic feature of adherent-invasive Escherichia coli (AIEC)
    Margarita Martinez-Medina
    Laboratory of Molecular Microbiology, Biology Department, University of Girona, Spain
    BMC Microbiol 9:202. 2009
    ..Biofilm formation capacity was then contrasted with the AIEC phenotype, the serotype, the phylotype, and the presence of virulence genes...
  8. pmc The oxidoreductase DsbA plays a key role in the ability of the Crohn's disease-associated adherent-invasive Escherichia coli strain LF82 to resist macrophage killing
    Marie Agnès Bringer
    Pathogenie Bacterienne Intestinale, université Clermont I, USC INRA 2018, F 63000 Clermont Fd, France
    J Bacteriol 189:4860-71. 2007
    ..Finally, the CpxRA signaling pathway does not play a role in regulation of dsbA expression in AIEC LF82 bacteria under conditions similar to those of mature phagolysosomes...
  9. ncbi request reprint High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn's disease
    Arlette Darfeuille-Michaud
    Pathogenie Bacterienne Intestinale, Laboratoire de Bacteriologie, Universite d Auvergne, Clermont Ferrand, France
    Gastroenterology 127:412-21. 2004
    ..This study was performed to assess the prevalence of AIEC associated with intestinal mucosa of patients with CD, ulcerative colitis (UC), and of controls...
  10. doi request reprint Western diet induces dysbiosis with increased E coli in CEABAC10 mice, alters host barrier function favouring AIEC colonisation
    Margarita Martinez-Medina
    Clermont Universite, Microbe intestin inflammation et Susceptibilité de l Hôte, UMR1071 Inserm Université d Auvergne M2iSH, Clermont Ferrand, France
    Gut 63:116-24. 2014
    ..We assessed the effects of a high fat/high sugar (HF/HS) Western diet on gut microbiota composition, barrier integrity and susceptibility to infection in transgenic CEABAC10 mice expressing human CEACAMs...
  11. pmc Role of decreased levels of Fis histone-like protein in Crohn's disease-associated adherent invasive Escherichia coli LF82 bacteria interacting with intestinal epithelial cells
    Sylvie Miquel
    Clermont Universite, Universite d Auvergne, Clermont Ferrand, France
    J Bacteriol 192:1832-43. 2010
    ..Thus, by maintaining type 1 pilus expression, AIEC bacteria, which interact with the gut mucosa, have greater ability to colonize and to induce inflammation in CD patients...
  12. pmc Involvement of lipoprotein NlpI in the virulence of adherent invasive Escherichia coli strain LF82 isolated from a patient with Crohn's disease
    Nicolas Barnich
    Pathogenie Bacterienne Intestinale, Laboratoire de Bacteriologie, Universite d Auvergne, 63001 Clermont Ferrand, France
    Infect Immun 72:2484-93. 2004
    ....
  13. doi request reprint Defects in autophagy favour adherent-invasive Escherichia coli persistence within macrophages leading to increased pro-inflammatory response
    Pierre Lapaquette
    Clermont Universite, Universite d Auvergne, UMR Inserm Université d Auvergne U1071, USC INRA 2018, Clermont Ferrand, France
    Cell Microbiol 14:791-807. 2012
    ..On the basis of our findings, we speculate that stimulating autophagy in CD patients would be a powerful therapeutic strategy to concomitantly restrain intracellular AIEC replication and slow down the inflammatory response...
  14. doi request reprint Adherent-invasive Escherichia coli induce claudin-2 expression and barrier defect in CEABAC10 mice and Crohn's disease patients
    Jérémy Denizot
    Clermont Universite, Universite d Auvergne, Pathogenie Bacterienne Intestinale, JE2526, Clermont Ferrand F 63001, France
    Inflamm Bowel Dis 18:294-304. 2012
    ..Since intestinal permeability is significantly increased in CD patients, we aimed at investigating whether and how AIEC alter barrier function...
  15. doi request reprint Bile salts induce long polar fimbriae expression favouring Crohn's disease-associated adherent-invasive Escherichia coli interaction with Peyer's patches
    Benoit Chassaing
    Clermont Universite, UMR 1071 Inserm Université Auvergne, Clermont Ferrand 63000, France
    Environ Microbiol 15:355-71. 2013
    ..The FhlA transcriptional factor was found to be a key bacterial regulator at the origin of LPF expression in the presence of bile salts...
  16. doi request reprint Crohn's disease-associated adherent invasive Escherichia coli modulate levels of microRNAs in intestinal epithelial cells to reduce autophagy
    Hang Thi Thu Nguyen
    M2iSH, UMR 1071 Inserm University of Auvergne, Clermont Ferrand, France INRA USC 2018, Clermont Ferrand, France Electronic address
    Gastroenterology 146:508-19. 2014
    ..We investigated the mechanism by which AIEC infection alters the expression of microRNAs and the host immune response...
  17. pmc CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease
    Nicolas Barnich
    Groupe de Recherche Pathogénie Bactérienne Intestinale, Universite d Auvergne, USC INRA 2018, Clermont Ferrand, France
    J Clin Invest 117:1566-74. 2007
    ....
  18. pmc Point mutations in FimH adhesin of Crohn's disease-associated adherent-invasive Escherichia coli enhance intestinal inflammatory response
    Nicolas Dreux
    M2iSH, UMR1071 Inserm, Universite d Auvergne, USC INRA 2018, Clermont Ferrand, France
    PLoS Pathog 9:e1003141. 2013
    ..coli isolated from IBD patients for diagnostic or epidemiological studies and to identify new strategies for therapeutic intervention to block the interaction between AIEC and gut mucosa in the early stages of IBD...
  19. pmc Strong decrease in invasive ability and outer membrane vesicle release in Crohn's disease-associated adherent-invasive Escherichia coli strain LF82 with the yfgL gene deleted
    Nathalie Rolhion
    Pathogenie Bacterienne Intestinale, Laboratoire de Bacteriologie, Universite d Auvergne, CBRV, 28 Place Henri Dunant, 63001 Clermont Ferrand, France
    J Bacteriol 187:2286-96. 2005
    ..Thus, deletion of the yfgL gene in strain LF82 resulted in a decreased ability to invade intestinal epithelial cells and a decreased release of outer membrane vesicles...
  20. pmc Colon cancer-associated B2 Escherichia coli colonize gut mucosa and promote cell proliferation
    Jennifer Raisch
    Jennifer Raisch, Emmanuel Buc, Mathilde Bonnet, Pierre Sauvanet, Emilie Vazeille, Amélie de Vallée, Denis Pezet, Richard Bonnet, Marie Agnès Bringer, Arlette Darfeuille Michaud, Clermont Universite, UMR1071 Inserm Université d Auvergne and INRA USC2018, 63000 Clermont Ferrand, France
    World J Gastroenterol 20:6560-72. 2014
    ..To provide further insight into the characterization of mucosa-associated Escherichia coli (E. coli) isolated from the colonic mucosa of cancer patients...
  21. doi request reprint Crohn's disease-associated Escherichia coli LF82 aggravates colitis in injured mouse colon via signaling by flagellin
    Frederic A Carvalho
    University Clermont 1, Pathogenie Bacterienne Intestinale, USC INRA 2018, Clermont Ferrand, France
    Inflamm Bowel Dis 14:1051-60. 2008
    ..We investigated in a mouse model of colonic inflammation the behavior of virulent AIEC reference bacteria LF82 compared to that of nonflagellated LF82 mutants...
  22. pmc High prevalence of mucosa-associated E. coli producing cyclomodulin and genotoxin in colon cancer
    Emmanuel Buc
    UMR 1071 Inserm Université d Auvergne, Clermont Universite, Clermont Ferrand, France
    PLoS ONE 8:e56964. 2013
    ..5%, p = 0.91). In conclusion, cyclomodulin-producing E. coli belonging mostly to B2 phylogroup colonize the colonic mucosa of patients with CRC...
  23. doi request reprint Abnormalities in the handling of intracellular bacteria in Crohn's disease
    Pierre Lapaquette
    Clermont Universite, Clermont Ferrand, France
    J Clin Gastroenterol 44:S26-9. 2010
    ....
  24. doi request reprint Chromosome-mediated OXA-48 carbapenemase in highly virulent Escherichia coli
    Racha Beyrouthy
    Clermont Universite, UMR 1071 Inserm Université d Auvergne, 63000 Clermont Ferrand, France
    J Antimicrob Chemother 68:1558-61. 2013
    ..In this work, we investigated the virulence and resistance mechanism of an extraintestinal pathogenic Escherichia coli (ExPEC) strain (LEB15) that exhibited decreased susceptibility to carbapenems...
  25. ncbi request reprint The endoplasmic reticulum stress response chaperone: Gp96, a host receptor for Crohn disease-associated adherent-invasive Escherichia coli
    Nathalie Rolhion
    Clermont Universite, Universite d Auvergne, JE2526, USC INRA 2018, CNRH Auvergne, France
    Gut Microbes 2:115-9. 2011
    ..In this addendum, we provide a synopsis on current data concerning AIEC virulence, summarize our recent findings and also discuss, in more detail, unresolved issues and the potential implications of our findings. ..
  26. ncbi request reprint The Crohn's disease-associated adherent-invasive Escherichia coli strain LF82 replicates in mature phagolysosomes within J774 macrophages
    Marie Agnès Bringer
    Pathogenie Bacterienne Intestinale, Laboratoire de Bacteriologie, USC INRA 2018, Universite d Auvergne, CBRV, Clermont Ferrand, France
    Cell Microbiol 8:471-84. 2006
    ..Thus, evidence is provided that AIEC LF82 bacteria do not escape from the endocytic pathway but undergo normal interaction with host endomembrane organelles and replicate within acidic and cathepsin D-positive vacuolar phagolysosomes...
  27. pmc Crohn disease--associated adherent-invasive E. coli bacteria target mouse and human Peyer's patches via long polar fimbriae
    Benoit Chassaing
    Clermont Universite, Université Auvergne, JE2526, USC INRA 2018, Clermont Ferrand, Auvergne, France
    J Clin Invest 121:966-75. 2011
    ..In conclusion, we have identified LPF as a key factor for AIEC to target PPs. This could be the missing link between AIEC colonization and the presence of early lesions in the PPs of CD patients...
  28. pmc The σE pathway is involved in biofilm formation by Crohn's disease-associated adherent-invasive Escherichia coli
    Benoit Chassaing
    Clermont Universite, UMR 1071 Inserm Université Auvergne, Clermont Ferrand, France
    J Bacteriol 195:76-84. 2013
    ..This indicates that targeting of the σ(E) pathway could be a very potent therapeutic strategy by which to interfere with the ability of AIEC to form biofilm on the gut mucosa of Crohn's disease patients...
  29. doi request reprint Abnormal CEACAM6 expression in Crohn disease patients favors gut colonization and inflammation by adherent-invasive E. coli
    Nicolas Barnich
    Clermont Universite, INRA, Clermont Ferrand, France
    Virulence 1:281-2. 2010
    ....
  30. doi request reprint Colonization of the human gut by E. coli and colorectal cancer risk
    Mathilde Bonnet
    Authors Affiliations Clermont Université, UMR 1071Inserm Université d Auvergne Institut National de la Recherche Agronomique INRA, USC 2018 and Centre Hospitalier Universitaire, Clermont Ferrand, France
    Clin Cancer Res 20:859-67. 2014
    ..We assessed carcinogenic properties of a colon cancer-associated E. coli strain in multiple intestinal neoplasia (Min) mice...
  31. pmc HtrA stress protein is involved in intramacrophagic replication of adherent and invasive Escherichia coli strain LF82 isolated from a patient with Crohn's disease
    Marie Agnès Bringer
    Pathogenie Bacterienne Intestinale, Laboratoire de Bacteriologie, Universite d Auvergne, CBRV, 28 Place Henri Dunant, 63001 Clermont Ferrand, France
    Infect Immun 73:712-21. 2005
    ..coli K-12 intramacrophagic bacteria, indicating that the AIEC LF82 genetic background is crucial for induction of htrA gene transcription during phagocytosis...
  32. ncbi request reprint OmpC and the sigma(E) regulatory pathway are involved in adhesion and invasion of the Crohn's disease-associated Escherichia coli strain LF82
    Nathalie Rolhion
    Univ Clermont 1, Pathogenie Bacterienne Intestinale, USC INRA 2018, Clermont Ferrand F 63000, France
    Mol Microbiol 63:1684-700. 2007
    ..Increased expression of RpoE was observed in wild-type strain LF82 at high osmolarity. Hence, the role of OmpC in the AIEC LF82 adhesion and invasion is indirect and involves the sigma(E) regulatory pathway...
  33. ncbi request reprint The flagellar sigma factor FliA regulates adhesion and invasion of Crohn disease-associated Escherichia coli via a cyclic dimeric GMP-dependent pathway
    Laurent Claret
    université Clermont 1, Pathogenie Bacterienne Intestinale, Institut National de la Recherche Agronomique, Unité Sous Contrat 2018 USC INRA 2018, Clermont Ferrand F 63001, France
    J Biol Chem 282:33275-83. 2007
    ..These findings show that in the AIEC strain LF82, FliA is a key regulatory component linking flagellar and type 1 pili synthesis and that its effect on type 1 pili is mediated, at least in part, via a c-di-GMP-dependent pathway...
  34. ncbi request reprint Role of bacteria in the etiopathogenesis of inflammatory bowel disease
    Nicolas Barnich
    Pathogenie Bacterienne Intestinale, USC INRA 2018, Universite d Auvergne, Centre Biomedical de Recherche et Valorisation, 28 Place Henri Dunant, Clermont Ferrand 63000, France
    World J Gastroenterol 13:5571-6. 2007
    ....
  35. pmc Crohn's disease-associated adherent-invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly
    Pierre Lapaquette
    Univ Clermont, Pathogenie Bacterienne Intestinale, USC INRA, Clermont Ferrand, France
    Cell Microbiol 12:99-113. 2010
    ..coli strains associated with ileal CD. AIEC infection in patients with polymorphisms in autophagy genes may have a significant impact on the outcome of intestinal inflammation...
  36. ncbi request reprint Adherent-invasive Escherichia coli in inflammatory bowel disease
    Nathalie Rolhion
    Pathogenie Bacterienne Intestinale, Univ Clermont 1, USC INRA 2018, Clermont Ferrand, France
    Inflamm Bowel Dis 13:1277-83. 2007
    ..Mucosa-associated E. coli in patients with UC can adhere to intestinal epithelial cells and induce the secretion of IL-8, but there is no evidence that these E. coli strains are invasive...
  37. ncbi request reprint Regulatory and functional co-operation of flagella and type 1 pili in adhesive and invasive abilities of AIEC strain LF82 isolated from a patient with Crohn's disease
    Nicolas Barnich
    Pathogenie Bacterienne Intestinale, Laboratoire de Bacteriologie, Universite d Auvergne, 28 Place Henri Dunant, 63001 Clermont Ferrand, France
    Mol Microbiol 48:781-94. 2003
    ....
  38. pmc Lactobacillus casei DN-114 001 inhibits the ability of adherent-invasive Escherichia coli isolated from Crohn's disease patients to adhere to and to invade intestinal epithelial cells
    Isabelle Ingrassia
    Pathogenie Bacterienne Intestinale, Laboratoire de Bacteriologie, CBRV, 28 Place Henri Dunant, 63000 Clermont Ferrand, France
    Appl Environ Microbiol 71:2880-7. 2005
    ..As Lactobacillus casei DN-114 001 strongly inhibits interaction of adherent-invasive E. coli with intestinal epithelial cells, this finding suggests that the probiotic strain could be of therapeutic value in Crohn's disease...
  39. doi request reprint Etiology of Crohn's disease: many roads lead to autophagy
    Pierre Lapaquette
    Clermont Universite, Universite d Auvergne, Clermont Ferrand, France
    J Mol Med (Berl) 90:987-96. 2012
    ....
  40. doi request reprint Replication of Crohn's disease-associated AIEC within macrophages is dependent on TNF-α secretion
    Marie Agnès Bringer
    Clermont Universite, Universite d Auvergne, JE2526, Clermont Ferrand, France
    Lab Invest 92:411-9. 2012
    ..Neutralizing TNF-α secreted by infected macrophages may represent an effective strategy to control AIEC intracellular replication...
  41. pmc Interactions with M cells and macrophages as key steps in the pathogenesis of enterohemorrhagic Escherichia coli infections
    Lucie Etienne-Mesmin
    Clermont Universite, Universite d Auvergne, Centre de Recherche en Nutrition Humaine Auvergne, JE 2526 Evolution des bactéries pathogènes et susceptibilité génétique de l hôte, Clermont Ferrand, France
    PLoS ONE 6:e23594. 2011
    ..A new model for EHEC infection in humans is proposed that could help in a fuller understanding of EHEC-associated diseases...
  42. doi request reprint Analysis of structure-function relationships in the colibactin-maturating enzyme ClbP
    Antony Cougnoux
    M2iSH, Inserm U1071, INRA USC2018, Clermont Universite, Universite d Auvergne, 63000 Clermont Ferrand, France
    J Mol Biol 424:203-14. 2012
    ..Overall, these results suggest a model for precolibactin activation by ClbP and pave a way for the design of inhibitors targeting colibactin production...
  43. ncbi request reprint Adherent-invasive Escherichia coli and Crohn's disease
    Nicolas Barnich
    Univ Clermont 1, Pathogenie Bacterienne Intestinale, USC INRA 2018 CBRV, Clermont Ferrand, France
    Curr Opin Gastroenterol 23:16-20. 2007
    ..Herein, we review reports concerning the association of pathogenic Escherichia coli with the intestinal mucosa of Crohn's disease patients...
  44. doi request reprint The commensal microbiota and enteropathogens in the pathogenesis of inflammatory bowel diseases
    Benoit Chassaing
    Clermont Universite, Universite d Auvergne, Jeune Equipe JE 2526, Clermont Ferrand, France
    Gastroenterology 140:1720-28. 2011
    ....
  45. pmc Crohn's disease adherent-invasive Escherichia coli colonize and induce strong gut inflammation in transgenic mice expressing human CEACAM
    Frederic A Carvalho
    université Clermont 1, Pathogenie Bacterienne Intestinale, JE2526, Unité Sous Contrat Institut National de la Recherche Agronomique 2018, Clermont Ferrand F 63001, France
    J Exp Med 206:2179-89. 2009
    ..Thus, targeting AIEC adhesion to gut mucosa represents a new strategy for clinicians to prevent and/or to treat ileal CD...
  46. ncbi request reprint Pathogenic Escherichia coli in inflammatory bowel diseases Proceedings of the 1st International Meeting on E. coli and IBD, June 2007, Lille, France
    Arlette Darfeuille-Michaud
    Pathogenie Bacterienne Intestinale, université d Auvergne Clermont 1, USC INRA 2018, Clermont Ferrand, France
    J Crohns Colitis 2:255-62. 2008
    ..This paper summarizes most data that were exchanged during this day and represents an update on the potential role of pathogenic E. coli in inflammatory bowel diseases...
  47. ncbi request reprint Klebsiella pneumoniae type 3 pili facilitate adherence and biofilm formation on abiotic surfaces
    Patrick Di Martino
    Laboratoire ERRMECe équipe Microbiologie, U F R Sciences et Techniques, 95302 Cergy Pontoise, France
    Res Microbiol 154:9-16. 2003
    ..Thus, type 3 pili constitute the main K. pneumoniae adhesive factor, facilitating adherence and biofilm formation on abiotic surfaces of strains of different origins...
  48. ncbi request reprint Role of EHEC O157:H7 virulence factors in the activation of intestinal epithelial cell NF-kappaB and MAP kinase pathways and the upregulated expression of interleukin 8
    M Cecilia Berin
    Laboratory of Mucosal Immunology, University of California at San Diego, La Jolla, CA 92093 0623, USA
    Cell Microbiol 4:635-48. 2002
    ..The activation of proinflammatory signals in human colon epithelial cells in response to this non-invasive pathogen appears to depend to a significant extent on H7 flagellin...
  49. doi request reprint Pathogenic agents in inflammatory bowel diseases
    Guillaume Pineton de Chambrun
    Clinic of Digestive Disorders and Nutrition, Hopital Claude Huriez, CHRU Lille, France
    Curr Opin Gastroenterol 24:440-7. 2008
    ..Infectious agents are still thought to be involved in the origin of inflammatory bowel disease. The focus in recent years has been more on Mycobacterium avium subsp paratuberculosis, adherent-invasive Escherichia coli or yeasts...