R Cursio

Summary

Country: France

Publications

  1. doi request reprint Liver apoptosis following normothermic ischemia-reperfusion: in vivo evaluation of caspase activity by FLIVO assay in rats
    R Cursio
    Laboratoire de Recherches Chirurgicales, IFR 50, Faculte de Medecine, Universite de Nice Sophia Antipolis, Nice, France
    Transplant Proc 40:2038-41. 2008
  2. ncbi request reprint Rat liver injury after normothermic ischemia is prevented by a phosphinic matrix metalloproteinase inhibitor
    Raffaele Cursio
    Laboratoire de Recherches Chirurgicales, IFR50, France
    FASEB J 16:93-5. 2002
  3. doi request reprint Induction of different types of cell death after normothermic liver ischemia-reperfusion
    R Cursio
    Inserm UMR895, Faculte des Sciences, Universite de Nice Sophia Antipolis, Nice, France
    Transplant Proc 42:3977-80. 2010
  4. doi request reprint Tyrosine phosphorylation of insulin receptor substrates during ischemia/reperfusion-induced apoptosis in rat liver
    Raffaele Cursio
    Laboratoire de Recherches Chirurgicales, IFR 50, Faculte de Medecine, Universite de Nice Sophia Antipolis, Nice, France
    Langenbecks Arch Surg 394:123-31. 2009
  5. ncbi request reprint Iatrogenic bladder stone formation on absorbable suture 3-years after radical prostatectomy
    R Cursio
    Service d Urologie, Centre Hospitalier, Princesse Grace de Monaco, Monaco
    Minerva Urol Nefrol 54:127-8. 2002
  6. doi request reprint Liver HIF-1 alpha induction precedes apoptosis following normothermic ischemia-reperfusion in rats
    R Cursio
    Laboratoire de Recherches Chirurgicales, IFR 50, Faculte de Medecine, Universite de Nice Sophia Antipolis, Nice, France
    Transplant Proc 40:2042-5. 2008
  7. ncbi request reprint Fas ligand expression following normothermic liver ischemia-reperfusion
    Raffaele Cursio
    Laboratoire de Recherches Chirurgicales, IFR 50, Universite de Nice Sophia Antipolis, Nice, France
    J Surg Res 125:30-6. 2005
  8. ncbi request reprint Involvement of protein kinase B and mitogen-activated protein kinases in experimental normothermic liver ischaemia-reperfusion injury
    R Cursio
    Laboratoire de Recherches Chirurgicales, Faculte de Medecine, Universite de Nice, 28 Avenue de Valombrose, 06107 Nice Cedex 2, France
    Br J Surg 93:752-61. 2006
  9. ncbi request reprint Alterations in protein tyrosine kinase pathways in rat liver following normothermic ischemia-reperfusion
    R Cursio
    Laboratoire de Recherches Chirurgicales, IFR 50, Faculte de Medecine, Universite de Nice Sophia Antipolis, Nice, France
    Transplant Proc 38:3362-5. 2006
  10. doi request reprint Cryopreserved porcine hepatocytes: expression and induction of cytochrome P450, isoform CYP2E1
    E Baldini
    Laboratoire de Recherches Chirurgicales, IFR 50, Faculte de Medecine, Universite de Nice Sophia Antipolis, Nice, France
    Transplant Proc 41:1367-9. 2009

Collaborators

  • C Miele
  • Dominique Crenesse
  • C Heurteaux
  • E Baldini
  • J Gugenheim
  • R Rahmani
  • J Mouiel
  • V Raimondi
  • J Honiger
  • M C Saint-Paul
  • P Bayer
  • A Margara
  • Roberto Bini
  • A El-Ghoneimi
  • G DeSousa
  • G de Sousa
  • Bernard Mari
  • B Rossi
  • Jean Giudicelli
  • Jean Gugenheim
  • A Schmid-Alliana
  • M Tovey
  • Patrick Auberger
  • Nathalie Belhacene
  • A Lasfar
  • Giorgio Olivero
  • Bernard Ferrua
  • J F Michiels
  • Paolo Cotogni

Detail Information

Publications16

  1. doi request reprint Liver apoptosis following normothermic ischemia-reperfusion: in vivo evaluation of caspase activity by FLIVO assay in rats
    R Cursio
    Laboratoire de Recherches Chirurgicales, IFR 50, Faculte de Medecine, Universite de Nice Sophia Antipolis, Nice, France
    Transplant Proc 40:2038-41. 2008
    ..005), compared with nonischemic liver lobes. In conclusion, 120-minute normothermic liver I-R resulted in increased caspase-3- and -7-specific activities and in liver cell apoptosis...
  2. ncbi request reprint Rat liver injury after normothermic ischemia is prevented by a phosphinic matrix metalloproteinase inhibitor
    Raffaele Cursio
    Laboratoire de Recherches Chirurgicales, IFR50, France
    FASEB J 16:93-5. 2002
    ..We therefore propose that MMP inhibitors may be of clinical relevance in liver-associated ischemic diseases or after liver transplantation...
  3. doi request reprint Induction of different types of cell death after normothermic liver ischemia-reperfusion
    R Cursio
    Inserm UMR895, Faculte des Sciences, Universite de Nice Sophia Antipolis, Nice, France
    Transplant Proc 42:3977-80. 2010
    ..005). In conclusion, 120 minutes normothermic liver I-R resulted in increased autophagic, apoptotic and necrotic cell death...
  4. doi request reprint Tyrosine phosphorylation of insulin receptor substrates during ischemia/reperfusion-induced apoptosis in rat liver
    Raffaele Cursio
    Laboratoire de Recherches Chirurgicales, IFR 50, Faculte de Medecine, Universite de Nice Sophia Antipolis, Nice, France
    Langenbecks Arch Surg 394:123-31. 2009
    ..The aim of this study was to evaluate the effect of normothermic liver I/R-induced apoptosis on phosphorylation and activation of signal proteins in tyrosine kinase pathways...
  5. ncbi request reprint Iatrogenic bladder stone formation on absorbable suture 3-years after radical prostatectomy
    R Cursio
    Service d Urologie, Centre Hospitalier, Princesse Grace de Monaco, Monaco
    Minerva Urol Nefrol 54:127-8. 2002
    ..The case of a 68-year-old white man, who had formed a large bladder stone on absorbable suture 3 years after radical prostatectomy, is reported. Endoscopic lithotripsy of the bladder calculi was performed and the suture was removed...
  6. doi request reprint Liver HIF-1 alpha induction precedes apoptosis following normothermic ischemia-reperfusion in rats
    R Cursio
    Laboratoire de Recherches Chirurgicales, IFR 50, Faculte de Medecine, Universite de Nice Sophia Antipolis, Nice, France
    Transplant Proc 40:2042-5. 2008
    ..Liver apoptosis was significantly (P< .005) increased at 3 and 6 hours after reperfusion. In conclusion, normothermic liver I-R leads to increased liver expression of HIF-1alpha and apoptosis...
  7. ncbi request reprint Fas ligand expression following normothermic liver ischemia-reperfusion
    Raffaele Cursio
    Laboratoire de Recherches Chirurgicales, IFR 50, Universite de Nice Sophia Antipolis, Nice, France
    J Surg Res 125:30-6. 2005
    ..The aim of this study was to evaluate the role of the pro-apoptotic molecule Fas Ligand (FasL) in 120 min normothermic ischemia-reperfusion (I-R) induced apoptosis in rat liver treated or not with Z-Asp-cmk caspase inhibitor...
  8. ncbi request reprint Involvement of protein kinase B and mitogen-activated protein kinases in experimental normothermic liver ischaemia-reperfusion injury
    R Cursio
    Laboratoire de Recherches Chirurgicales, Faculte de Medecine, Universite de Nice, 28 Avenue de Valombrose, 06107 Nice Cedex 2, France
    Br J Surg 93:752-61. 2006
    ....
  9. ncbi request reprint Alterations in protein tyrosine kinase pathways in rat liver following normothermic ischemia-reperfusion
    R Cursio
    Laboratoire de Recherches Chirurgicales, IFR 50, Faculte de Medecine, Universite de Nice Sophia Antipolis, Nice, France
    Transplant Proc 38:3362-5. 2006
    ..In conclusion, 1-R led to alterations in protein tyrosine phosphorylation and increased expression of VEGF in rat liver...
  10. doi request reprint Cryopreserved porcine hepatocytes: expression and induction of cytochrome P450, isoform CYP2E1
    E Baldini
    Laboratoire de Recherches Chirurgicales, IFR 50, Faculte de Medecine, Universite de Nice Sophia Antipolis, Nice, France
    Transplant Proc 41:1367-9. 2009
    ..Long-term cryopreserved porcine hepatocytes preserved their capacity for CYP2E1 protein expression, although exposure of these hepatocytes to CYP inducers did not modify the CYP2E1 protein expression...
  11. ncbi request reprint Intermittent ischemia reduces warm hypoxia-reoxygenation-induced JNK(1)/SAPK(1) activation and apoptosis in rat hepatocytes
    D Crenesse
    Laboratoire de Physiologie, Faculte de Medecine, Universite de Nice Sophia Antipolis, Nice, France
    Hepatology 34:972-8. 2001
    ..Intermittent ischemia is a powerful, protective way to reduce I/R damage of the liver, by reduction of JNK(1)/SAPK(1) activation associated with a down-regulation of caspase 3 activity, which leads to inhibition of hepatocyte apoptosis...
  12. ncbi request reprint Rat liver ischemia-reperfusion-induced apoptosis and necrosis are decreased by FK506 pretreatment
    Dominique Crenesse
    Laboratoire de Physiologie, Faculte de Medecine, Universite de Nice Sophia Antipolis, Av de Valombrose 06107 Nice 2, France
    Eur J Pharmacol 473:177-84. 2003
    ..In hypoxia-reoxygenation-subjected hepatocytes, tacrolimus reduced JNK1/SAPK1 and caspase 3 activation. In the liver, tacrolimus prevented ischemia-reperfusion-induced apoptosis and necrosis...
  13. ncbi request reprint Diltiazem reduces apoptosis in rat hepatocytes subjected to warm hypoxia-reoxygenation
    Dominique Crenesse
    Laboratoire de Physiologie, Faculte de Medecine, Universite de Nice Sophia Antipolis, France
    Pharmacology 65:87-95. 2002
    ..Diltiazem inhibited H/R-induced JNK(1)/SAPK(1) activation and decreased apoptosis. It could be used to improve postoperative liver function...
  14. ncbi request reprint Inhibition of tumor necrosis factor alpha gene transcription by pentoxifylline reduces normothermic liver ischemia-reperfusion injury in rats
    A El-Ghoneimi
    Laboratoire de Recherches Chirurgicales, IFR 50, Faculte de Medecine, Universite de Nice Sophia Antipolis, Nice, France
    Transplant Proc 39:1761-4. 2007
    ..In conclusion, PTX inhibits liver TNFalpha gene transcription, decreases serum TNFalpha levels, and reduces liver injury following normothermic I-R...
  15. doi request reprint Peritoneal implantation of cryopreserved encapsulated porcine hepatocytes in rats without immunosuppression: viability and function
    E Baldini
    Laboratoire de Recherches Chirurgicales, IFR 50, Faculte de Medecine, Universite de Nice Sophia Antipolis, Nice, France
    Transplant Proc 40:2049-52. 2008
    ..In conclusion, long-term cryopreservation of porcine hepatocytes resulted in retention of their biological activity and in significant viability when transplanted into the rat peritoneum without immunosuppression...
  16. ncbi request reprint Effect of caspase inhibition on thymic apoptosis in hemorrhagic shock
    Roberto Bini
    Chirurgia d Urgenza, Dipartimento di Discipline Medico Chirurgiche, Universit a di Torino, Torino, Italy
    J Invest Surg 20:97-103. 2007
    ..Our results suggest that postinjury caspase inhibition does not attenuate organ dysfunctions, and also does not permanently reduce TA induced by HS and resuscitation in rats...