Mathieu Coureuil

Summary

Country: France

Publications

  1. doi request reprint Mechanisms of meningeal invasion by a bacterial extracellular pathogen, the example of Neisseria meningitidis
    Olivier Join-Lambert
    INSERM, Unité 570, 156 rue de Vaugirard, 75015 Paris, France
    Prog Neurobiol 91:130-9. 2010
  2. doi request reprint Meningococcal type IV pili recruit the polarity complex to cross the brain endothelium
    Mathieu Coureuil
    Universite Paris Descartes, Faculte de Medecine, Inserm U 570, 75015 Paris, France
    Science 325:83-7. 2009
  3. doi request reprint Meningococcus Hijacks a β2-adrenoceptor/β-Arrestin pathway to cross brain microvasculature endothelium
    Mathieu Coureuil
    Universite Paris Descartes, Faculte de Medecine, 75006 Paris, France
    Cell 143:1149-60. 2010
  4. pmc Two strikingly different signaling pathways are induced by meningococcal type IV pili on endothelial and epithelial cells
    Hervé Lecuyer
    Universite Paris Descartes, Sorbonne Paris Cité, Faculte de Medecine, INSERM U1002, and Assistance Publique Hopitaux de Paris, Hopital Necker Enfants Malades, Paris, France
    Infect Immun 80:175-86. 2012
  5. pmc The meningococcal minor pilin PilX is responsible for type IV pilus conformational changes associated with signaling to endothelial cells
    Terry Brissac
    Faculte de Medecine, Universite Paris Descartes, Sorbonne Paris Cité, Paris, France
    Infect Immun 80:3297-306. 2012
  6. doi request reprint Chronic meningococcemia cutaneous lesions involve meningococcal perivascular invasion through the remodeling of endothelial barriers
    Nicolas Dupin
    Universite Paris Descartes, Sorbonne Paris Cité, Paris, France
    Clin Infect Dis 54:1162-5. 2012

Collaborators

Detail Information

Publications6

  1. doi request reprint Mechanisms of meningeal invasion by a bacterial extracellular pathogen, the example of Neisseria meningitidis
    Olivier Join-Lambert
    INSERM, Unité 570, 156 rue de Vaugirard, 75015 Paris, France
    Prog Neurobiol 91:130-9. 2010
    ..meningitidis is also able to recruit the polarity complex Par3/Par6/aPKC that re-routes endothelial cell adhesion molecules of interendothelial junctions, opening a paracellular route for bacteria to cross the endothelial barrier...
  2. doi request reprint Meningococcal type IV pili recruit the polarity complex to cross the brain endothelium
    Mathieu Coureuil
    Universite Paris Descartes, Faculte de Medecine, Inserm U 570, 75015 Paris, France
    Science 325:83-7. 2009
    ....
  3. doi request reprint Meningococcus Hijacks a β2-adrenoceptor/β-Arrestin pathway to cross brain microvasculature endothelium
    Mathieu Coureuil
    Universite Paris Descartes, Faculte de Medecine, 75006 Paris, France
    Cell 143:1149-60. 2010
    ..The identification of the mechanism used for hijacking host cell signaling machineries opens perspectives for treatment and prevention of meningococcal infection...
  4. pmc Two strikingly different signaling pathways are induced by meningococcal type IV pili on endothelial and epithelial cells
    Hervé Lecuyer
    Universite Paris Descartes, Sorbonne Paris Cité, Faculte de Medecine, INSERM U1002, and Assistance Publique Hopitaux de Paris, Hopital Necker Enfants Malades, Paris, France
    Infect Immun 80:175-86. 2012
    ..These data demonstrate that even though pilus-mediated signaling induces an apparently similar cortical plaque, in epithelial and endothelial cell lineages, the signaling pathways are strikingly different in both models...
  5. pmc The meningococcal minor pilin PilX is responsible for type IV pilus conformational changes associated with signaling to endothelial cells
    Terry Brissac
    Faculte de Medecine, Universite Paris Descartes, Sorbonne Paris Cité, Paris, France
    Infect Immun 80:3297-306. 2012
    ..These data support a model in which surface-exposed motifs of PilX use forces generated by pilus retraction to promote conformational changes required for TFP-mediated signaling...
  6. doi request reprint Chronic meningococcemia cutaneous lesions involve meningococcal perivascular invasion through the remodeling of endothelial barriers
    Nicolas Dupin
    Universite Paris Descartes, Sorbonne Paris Cité, Paris, France
    Clin Infect Dis 54:1162-5. 2012
    ..Both in vivo and in vitro data suggest that, in these lesions, meningococci gain access from the capillary lumen to the peripheral extravascular compartment, in the absence of vascular dislocation, through a paraendothelial route...