Laure Coulombel

Summary

Country: France

Publications

  1. ncbi request reprint Identification of hematopoietic stem/progenitor cells: strength and drawbacks of functional assays
    Laure Coulombel
    INSERM U 421, Faculte de Medecine, 8 rue du General Sarrail, Creteil 94010, France
    Oncogene 23:7210-22. 2004
  2. pmc Human T-lymphoid progenitors generated in a feeder-cell-free Delta-like-4 culture system promote T-cell reconstitution in NOD/SCID/γc(-/-) mice
    Christian Reimann
    U768 INSERM, Universite Paris Descartes, Sorbonne Paris Cité, Faculte de Medecine, Paris, France
    Stem Cells 30:1771-80. 2012
  3. doi request reprint HIV-1 Nef protein expression in human CD34+ progenitors impairs the differentiation of an early T/NK cell precursor
    Céline Dorival
    INSERM U 841, Faculte de Medecine, Creteil, France
    Virology 377:207-15. 2008
  4. pmc The phosphate transporter PiT1 (Slc20a1) revealed as a new essential gene for mouse liver development
    Laurent Beck
    INSERM, U845, Centre de Recherche Croissance et Signalisation, Paris, France
    PLoS ONE 5:e9148. 2010
  5. ncbi request reprint [Stem cell therapy: an update]
    Laure Coulombel
    INSERM, Médecine Sciences, 2, rue d Alesia, 75014 Paris
    Bull Acad Natl Med 193:535-6. 2009
  6. ncbi request reprint [Targeting of CD44 to eradicate leukemic stem cells]
    Florence Smadja-Joffe
    Inserm U718, Hopital Saint Louis, 16, Rue de la Grange aux Belles, 75010 Paris, France
    Med Sci (Paris) 22:1003-5. 2006
  7. ncbi request reprint Short exposure to Notch ligand Delta-4 is sufficient to induce T-cell differentiation program and to increase the T cell potential of primary human CD34+ cells
    Nathalie Lefort
    INSERM U 421, Faculte de Medecine, Creteil, France
    Exp Hematol 34:1720-9. 2006
  8. ncbi request reprint [Adult stem cells: seing is not being]
    Laure Coulombel
    INSERM U 421, Faculte de Medecine, 8, rue du Général Sarrail, 94010 Creteil, France
    Med Sci (Paris) 19:683-94. 2003
  9. ncbi request reprint [Human hematopoiesis: from CD34 cells to T lymphocytes]
    Marina Cavazzana-Calvo
    Département de Biothérapie, Hopital Necker Enfants Malades, Inserm U768, 149, rue de Sevres, 75015 Paris, France
    Med Sci (Paris) 23:151-9. 2007
  10. ncbi request reprint Deregulated expression of HOXB4 enhances the primitive growth activity of human hematopoietic cells
    Christian Buske
    Terry Fox Laboratory, British Columbia Cancer Agency, and the Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada
    Blood 100:862-8. 2002

Collaborators

Detail Information

Publications18

  1. ncbi request reprint Identification of hematopoietic stem/progenitor cells: strength and drawbacks of functional assays
    Laure Coulombel
    INSERM U 421, Faculte de Medecine, 8 rue du General Sarrail, Creteil 94010, France
    Oncogene 23:7210-22. 2004
    ..Nevertheless, years of progress in the manipulation of hematopoietic stem cells have recently resulted in the purification of a cell subset that repopulates irradiated recipients with absolute efficiency...
  2. pmc Human T-lymphoid progenitors generated in a feeder-cell-free Delta-like-4 culture system promote T-cell reconstitution in NOD/SCID/γc(-/-) mice
    Christian Reimann
    U768 INSERM, Universite Paris Descartes, Sorbonne Paris Cité, Faculte de Medecine, Paris, France
    Stem Cells 30:1771-80. 2012
    ....
  3. doi request reprint HIV-1 Nef protein expression in human CD34+ progenitors impairs the differentiation of an early T/NK cell precursor
    Céline Dorival
    INSERM U 841, Faculte de Medecine, Creteil, France
    Virology 377:207-15. 2008
    ..Altogether, these data demonstrate that Nef interferes with the differentiation of a primitive lymphoid human precursor with a T/NK potential...
  4. pmc The phosphate transporter PiT1 (Slc20a1) revealed as a new essential gene for mouse liver development
    Laurent Beck
    INSERM, U845, Centre de Recherche Croissance et Signalisation, Paris, France
    PLoS ONE 5:e9148. 2010
    ..Although the importance of PiT1 in mineralizing processes have been demonstrated in vitro in osteoblasts, chondrocytes and vascular smooth muscle cells, in vivo evidence is missing...
  5. ncbi request reprint [Stem cell therapy: an update]
    Laure Coulombel
    INSERM, Médecine Sciences, 2, rue d Alesia, 75014 Paris
    Bull Acad Natl Med 193:535-6. 2009
    ..Only the former two categories have physiological functions: the first gives rise to tissues and organs while the second maintains tissue function during adulthood..
  6. ncbi request reprint [Targeting of CD44 to eradicate leukemic stem cells]
    Florence Smadja-Joffe
    Inserm U718, Hopital Saint Louis, 16, Rue de la Grange aux Belles, 75010 Paris, France
    Med Sci (Paris) 22:1003-5. 2006
  7. ncbi request reprint Short exposure to Notch ligand Delta-4 is sufficient to induce T-cell differentiation program and to increase the T cell potential of primary human CD34+ cells
    Nathalie Lefort
    INSERM U 421, Faculte de Medecine, Creteil, France
    Exp Hematol 34:1720-9. 2006
    ..The Notch pathway plays a key role in cell fate choices and in T-cell development. The goal of our study was to evaluate whether a short in vitro stimulation of the Notch pathway may alter human progenitor cell behavior...
  8. ncbi request reprint [Adult stem cells: seing is not being]
    Laure Coulombel
    INSERM U 421, Faculte de Medecine, 8, rue du Général Sarrail, 94010 Creteil, France
    Med Sci (Paris) 19:683-94. 2003
    ....
  9. ncbi request reprint [Human hematopoiesis: from CD34 cells to T lymphocytes]
    Marina Cavazzana-Calvo
    Département de Biothérapie, Hopital Necker Enfants Malades, Inserm U768, 149, rue de Sevres, 75015 Paris, France
    Med Sci (Paris) 23:151-9. 2007
    ....
  10. ncbi request reprint Deregulated expression of HOXB4 enhances the primitive growth activity of human hematopoietic cells
    Christian Buske
    Terry Fox Laboratory, British Columbia Cancer Agency, and the Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada
    Blood 100:862-8. 2002
    ..These findings reveal HOXB4 as a novel, positive regulator of the primitive growth activity of human hematopoietic progenitor cells and underline the relevance of early developmental factors for stem cell fate decisions...
  11. ncbi request reprint In vitro identification of human pro-B cells that give rise to macrophages, natural killer cells, and T cells
    Damien Reynaud
    Institut National de la Sante et de la Recherche Medicale INSERM, Paris, France
    Blood 101:4313-21. 2003
    ....
  12. ncbi request reprint Flt3-ligand induces adhesion of haematopoietic progenitor cells via a very late antigen (VLA)-4- and VLA-5-dependent mechanism
    Anne Solanilla
    UMR 5540, Universite Victor Segalen Bordeaux 2, Bordeaux, France
    Br J Haematol 120:782-6. 2003
    ..The control of HPC adhesiveness by FL is a previously unreported property of FL that may be important for the homing and the retention of flt3-expressing HPC within the bone marrow microenvironment...
  13. doi request reprint [Human reprogrammed iPS cells: so fast]
    Laure Coulombel
    Médecine sciences et Inserm U602, Hopital Paul Brousse, 94817 Villejuif Cedex, France
    Med Sci (Paris) 24:102-4. 2008
  14. ncbi request reprint [Intimate interactions between osteoblasts and hematopoietic stem cells]
    Laure Coulombel
    Med Sci (Paris) 20:156-8. 2004
  15. ncbi request reprint ["Turning stem cells into cures" or the answer of Arnie to George W]
    Laure Coulombel
    Médecine sciences et Inserm U602, Hopital Paul Brousse, 94817 Villejuif Cedex, France
    Med Sci (Paris) 23:102-4. 2007
  16. ncbi request reprint [Nanog and the magic wand]
    Laure Coulombel
    Med Sci (Paris) 22:828. 2006
  17. ncbi request reprint [Adult stem cells: who are they, what do they do?]
    Laure Coulombel
    Inserm U421 Faculté de médecine, 8 rue du Général Sarrail 94010 Créteil
    Bull Acad Natl Med 189:589-602; discussion 602-4. 2005
    ..In addition, serious doubts have been raised concerning the transdifferentiation potential of hematopoietic stem cells, underlining the need for care when interpreting findings that question long-established concepts...
  18. ncbi request reprint Bone marrow transplantation in mice leads to a minor population of hepatocytes that can be selectively amplified in vivo
    Vincent O Mallet
    Department of Genetics, Development and Molecular Pathology, Cochin Institute, Paris, France
    Hepatology 35:799-804. 2002
    ..We conclude that a selection strategy will be required to achieve a therapeutic level of liver repopulation with bone marrow-derived hepatocytes...