Francine Cote

Summary

Country: France

Publications

  1. pmc Maternal serotonin is crucial for murine embryonic development
    Francine Cote
    Universite Pierre et Marie Curie, Laboratoire de Genetique Moleculaire de la Neurotransmission et des Processus Neurodegeneratifs, CNRS, Unité Mixte de Recherche 7091, Hopital de la Pitie Salpetriere, Paris, France
    Proc Natl Acad Sci U S A 104:329-34. 2007
  2. doi Maternal serotonin influences cardiac function in adult offspring
    Cécile Fligny
    Unité Mixte de Recherche 7091 Centre National de la Recherche Scientifique Université Pierre et Marie Curie, Laboratoire de Genetique Moleculaire de la Neurotransmission et des Processus Neurodegeneratifs, Hopital de la Pitie Salpetriere, Paris, France
    FASEB J 22:2340-9. 2008
  3. ncbi [Abnormal cardiac activity in mice in the absence of peripheral serotonin synthesis]
    Francine Cote
    Laboratoire de Genetique Moleculaire de la Neurotransmission et des Processus Neurodegeneratifs, CNRS UMR7091, Batiment CERVI, Hopital de la Pitie Salpetriere, 83, Boulevard de l Hopital, 75013 Paris, France
    J Soc Biol 198:7-17. 2004
  4. ncbi Targeting conditional gene modification into the serotonin neurons of the dorsal raphe nucleus by viral delivery of the Cre recombinase
    Etienne Thévenot
    Laboratoire de Genetique Moleculaire de la Neurotransmission et des Processus Neurodegeneratifs, CNRS UMR 7091, Batiment CERVI, Hopital de la Pitie Salpetriere, 83 Boulevard de l hopital, 75013 Paris, France
    Mol Cell Neurosci 24:139-47. 2003
  5. pmc Disruption of the nonneuronal tph1 gene demonstrates the importance of peripheral serotonin in cardiac function
    Francine Cote
    Laboratoire de Genetique Moleculaire de la Neurotransmission et des Processus Neurodegeneratifs, CNRS, Unité Mixte de Recherche 7091 et Institut Fédératif de Recherche 70, Hopital de la Pitie Salpetriere, Paris, France
    Proc Natl Acad Sci U S A 100:13525-30. 2003
  6. ncbi Recent advances in understanding serotonin regulation of cardiovascular function
    Francine Cote
    Laboratoire de Genetique Moleculaire de la Neurotransmission et des Processus Neurodegeneratifs, Paris, France
    Trends Mol Med 10:232-8. 2004
  7. pmc Serotonin is a key factor for mouse red blood cell survival
    Pascal Amireault
    Faculte de Medecine, Université Paris Descartes Sorbonne Paris Cité, Institut Imagine, CNRS UMR 8147, Hôpital Universitaire Necker Enfants Malades, Paris, France Laboratoire d Excellence GR Ex, Paris, France Inserm UMR_S665, Institut National de la Transfusion Sanguine, Paris, France
    PLoS ONE 8:e83010. 2013
  8. ncbi An activin receptor IIA ligand trap corrects ineffective erythropoiesis in β-thalassemia
    Michael Dussiot
    1 INSERM UMR 1163, Laboratory of Cellular and Molecular Mechanisms of Hematological Disorders and Therapeutic Implications, Paris, France 2 Paris Descartes Sorbonne Paris Cité University, Imagine Institute, Paris, France 3 CNRS ERL 8254, Paris, France 4 Laboratory of Excellence GR Ex, Paris, France 5 INSERM U1149, Center for Research on Inflammation, Paris, France 6
    Nat Med 20:398-407. 2014
  9. pmc Life without peripheral serotonin: insights from tryptophan hydroxylase 1 knockout mice reveal the existence of paracrine/autocrine serotonergic networks
    Pascal Amireault
    Faculte de Medecine, Université Paris Descartes Sorbonne Paris Cité, Institut Imagine, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 8147, Hôpital Universitaire Necker Enfants Malades, 75015, Paris, France
    ACS Chem Neurosci 4:64-71. 2013
  10. doi Serotonin 5-HT2B receptors are required for bone-marrow contribution to pulmonary arterial hypertension
    Jean Marie Launay
    INSERM U942, Assistance Publique Hopitaux de Paris AP HP, Hopital Lariboisiere, Service de Biochimie, Paris, France
    Blood 119:1772-80. 2012

Collaborators

Detail Information

Publications12

  1. pmc Maternal serotonin is crucial for murine embryonic development
    Francine Cote
    Universite Pierre et Marie Curie, Laboratoire de Genetique Moleculaire de la Neurotransmission et des Processus Neurodegeneratifs, CNRS, Unité Mixte de Recherche 7091, Hopital de la Pitie Salpetriere, Paris, France
    Proc Natl Acad Sci U S A 104:329-34. 2007
    ..Consideration of the maternal genotype may thus help to clarify the influence of other genes in complex diseases, such as mental illness...
  2. doi Maternal serotonin influences cardiac function in adult offspring
    Cécile Fligny
    Unité Mixte de Recherche 7091 Centre National de la Recherche Scientifique Université Pierre et Marie Curie, Laboratoire de Genetique Moleculaire de la Neurotransmission et des Processus Neurodegeneratifs, Hopital de la Pitie Salpetriere, Paris, France
    FASEB J 22:2340-9. 2008
    ..Thus, plasma 5-HT concentration may be a useful index of heart failure. These findings show that cardiac function, through the plasma 5-HT concentration, is influenced by the maternal serotonergic status...
  3. ncbi [Abnormal cardiac activity in mice in the absence of peripheral serotonin synthesis]
    Francine Cote
    Laboratoire de Genetique Moleculaire de la Neurotransmission et des Processus Neurodegeneratifs, CNRS UMR7091, Batiment CERVI, Hopital de la Pitie Salpetriere, 83, Boulevard de l Hopital, 75013 Paris, France
    J Soc Biol 198:7-17. 2004
    ..The TPH1 -/- mutant may be a valuable model for investigating cardiovascular dysfunction such as those observed in human heart failure...
  4. ncbi Targeting conditional gene modification into the serotonin neurons of the dorsal raphe nucleus by viral delivery of the Cre recombinase
    Etienne Thévenot
    Laboratoire de Genetique Moleculaire de la Neurotransmission et des Processus Neurodegeneratifs, CNRS UMR 7091, Batiment CERVI, Hopital de la Pitie Salpetriere, 83 Boulevard de l hopital, 75013 Paris, France
    Mol Cell Neurosci 24:139-47. 2003
    ..Together, these results demonstrate that viral delivery provides a valuable method to target Cre recombination throughout the murine DRN and thus to study 5-HT neurotransmission by conditional gene modification...
  5. pmc Disruption of the nonneuronal tph1 gene demonstrates the importance of peripheral serotonin in cardiac function
    Francine Cote
    Laboratoire de Genetique Moleculaire de la Neurotransmission et des Processus Neurodegeneratifs, CNRS, Unité Mixte de Recherche 7091 et Institut Fédératif de Recherche 70, Hopital de la Pitie Salpetriere, Paris, France
    Proc Natl Acad Sci U S A 100:13525-30. 2003
    ..This report links loss of tph1 gene expression, and thus of peripheral 5-HT, to a cardiac dysfunction phenotype. The tph1-/- mutant may be valuable for investigating cardiovascular dysfunction observed in heart failure in humans...
  6. ncbi Recent advances in understanding serotonin regulation of cardiovascular function
    Francine Cote
    Laboratoire de Genetique Moleculaire de la Neurotransmission et des Processus Neurodegeneratifs, Paris, France
    Trends Mol Med 10:232-8. 2004
    ..This implies that the level of circulating serotonin is a key factor in maintaining normal cardiovascular activity. These findings offer new prospects for the use of serotonin in therapies for cardiovascular diseases...
  7. pmc Serotonin is a key factor for mouse red blood cell survival
    Pascal Amireault
    Faculte de Medecine, Université Paris Descartes Sorbonne Paris Cité, Institut Imagine, CNRS UMR 8147, Hôpital Universitaire Necker Enfants Malades, Paris, France Laboratoire d Excellence GR Ex, Paris, France Inserm UMR_S665, Institut National de la Transfusion Sanguine, Paris, France
    PLoS ONE 8:e83010. 2013
    ..We further demonstrate a link between oxidation and the removal of damaged RBC following transfusion, as supplementation with 5-HT improves RBC post-transfusion survival in a mouse model of blood banking. ..
  8. ncbi An activin receptor IIA ligand trap corrects ineffective erythropoiesis in β-thalassemia
    Michael Dussiot
    1 INSERM UMR 1163, Laboratory of Cellular and Molecular Mechanisms of Hematological Disorders and Therapeutic Implications, Paris, France 2 Paris Descartes Sorbonne Paris Cité University, Imagine Institute, Paris, France 3 CNRS ERL 8254, Paris, France 4 Laboratory of Excellence GR Ex, Paris, France 5 INSERM U1149, Center for Research on Inflammation, Paris, France 6
    Nat Med 20:398-407. 2014
    ....
  9. pmc Life without peripheral serotonin: insights from tryptophan hydroxylase 1 knockout mice reveal the existence of paracrine/autocrine serotonergic networks
    Pascal Amireault
    Faculte de Medecine, Université Paris Descartes Sorbonne Paris Cité, Institut Imagine, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 8147, Hôpital Universitaire Necker Enfants Malades, 75015, Paris, France
    ACS Chem Neurosci 4:64-71. 2013
    ....
  10. doi Serotonin 5-HT2B receptors are required for bone-marrow contribution to pulmonary arterial hypertension
    Jean Marie Launay
    INSERM U942, Assistance Publique Hopitaux de Paris AP HP, Hopital Lariboisiere, Service de Biochimie, Paris, France
    Blood 119:1772-80. 2012
    ..Thus, we demonstrate that activation of 5-HT(2B) receptors on bone marrow lineage progenitors is critical for the development of PAH...
  11. doi Mammalian prenatal development: the influence of maternally derived molecules
    Cécile Fligny
    LGN CNRS UMR 7091, Universite Pierre et Marie Curie, Hopital Pitie Salpetriere, Paris, France
    Bioessays 31:935-43. 2009
    ..This review focuses on environmental factors, specifically maternally derived molecules, to illustrate how they can influence in utero embryonic development and, by extension, adult life...
  12. doi Downregulation of basophil-derived IL-4 and in vivo T(H)2 IgE responses by serotonin and other organic cation transporter 3 ligands
    Elke Schneider
    Universite Paris Descartes, Faculte de Medecine, CNRS UMR 8147 Cytokines, Hematopoiesis and Immune Response, Hopital Necker, Paris, France
    J Allergy Clin Immunol 128:864-871.e2. 2011
    ....