Daniela Cota

Summary

Country: France

Publications

  1. ncbi request reprint Hypothalamic mTOR signaling regulates food intake
    Daniela Cota
    Department of Psychiatry, University of Cincinnati, Genome Research Institute, 2170 East Galbraith Road, Cincinnati, OH 45237, USA
    Science 312:927-30. 2006
  2. pmc Leucine supplementation protects from insulin resistance by regulating adiposity levels
    Elke Binder
    INSERM, Neurocentre Magendie, Physiopathologie de la Plasticité Neuronale, U862, Bordeaux, France Université de Bordeaux, Neurocentre Magendie, Physiopathologie de la Plasticité Neuronale, U862, Bordeaux, France
    PLoS ONE 8:e74705. 2013
  3. pmc Endocannabinoids measurement in human saliva as potential biomarker of obesity
    Isabelle Matias
    Group Endocannabinoids and Neuroadaptation, Institut National de la Sante et de la Recherche Medicale, Neurocentre Magendie, Physiophatologie de la Plasticité Neuronale, Bordeaux, France
    PLoS ONE 7:e42399. 2012
  4. pmc The role of hypothalamic mammalian target of rapamycin complex 1 signaling in diet-induced obesity
    Daniela Cota
    Department of Psychiatry, University of Cincinnati, Genome Research Institute, Cincinnati, Ohio 45237, USA
    J Neurosci 28:7202-8. 2008
  5. doi request reprint Mammalian target of rapamycin complex 1 (mTORC1) signaling in energy balance and obesity
    Daniela Cota
    INSERM U862, Avenir group Physiopathology of Energy Balance and Obesity, Universite de Bordeaux 2, Bordeaux, France
    Physiol Behav 97:520-4. 2009
  6. doi request reprint Food intake-independent effects of CB1 antagonism on glucose and lipid metabolism
    Daniela Cota
    Department of Psychiatry, University of Cincinnati, Genome Research Institute, Cincinnati, Ohio, USA
    Obesity (Silver Spring) 17:1641-5. 2009
  7. doi request reprint Hypothalamic CB1 cannabinoid receptors regulate energy balance in mice
    Pierre Cardinal
    Group Energy Balance and Obesity, Institut National de la Sante et de la Recherche Medicale, Unite 862, Neurocentre Magendie, 146 rue Leo Saignat, F 33077 Bordeaux, France
    Endocrinology 153:4136-43. 2012
  8. pmc Fatty acid synthase inhibitors modulate energy balance via mammalian target of rapamycin complex 1 signaling in the central nervous system
    Karine Proulx
    Department of Psychiatry, University of Cincinnati, Genome Research Institute, Cincinnati, OH, USA
    Diabetes 57:3231-8. 2008
  9. doi request reprint Role of the endocannabinoid system in energy balance regulation and obesity
    Daniela Cota
    Department of Psychiatry, University of Cincinnati, Cincinnati, OH 45237, USA
    Front Horm Res 36:135-45. 2008
  10. doi request reprint Leucine supplementation modulates fuel substrates utilization and glucose metabolism in previously obese mice
    Elke Binder
    Neurocentre Magendie, INSERM, Physiopathologie de la Plasticité Neuronale, U862, Bordeaux, France NeuroCentre Magendie, Physiopathologie de la Plasticité Neuronale, Universite de Bordeaux, U862, Bordeaux, France
    Obesity (Silver Spring) 22:713-20. 2014

Collaborators

Detail Information

Publications23

  1. ncbi request reprint Hypothalamic mTOR signaling regulates food intake
    Daniela Cota
    Department of Psychiatry, University of Cincinnati, Genome Research Institute, 2170 East Galbraith Road, Cincinnati, OH 45237, USA
    Science 312:927-30. 2006
    ..Thus, mTOR is a cellular fuel sensor whose hypothalamic activity is directly tied to the regulation of energy intake...
  2. pmc Leucine supplementation protects from insulin resistance by regulating adiposity levels
    Elke Binder
    INSERM, Neurocentre Magendie, Physiopathologie de la Plasticité Neuronale, U862, Bordeaux, France Université de Bordeaux, Neurocentre Magendie, Physiopathologie de la Plasticité Neuronale, U862, Bordeaux, France
    PLoS ONE 8:e74705. 2013
    ..However, the underlying mechanisms are at present unclear. Additionally, it is unclear whether leucine supplementation might be equally efficacious once obesity has developed...
  3. pmc Endocannabinoids measurement in human saliva as potential biomarker of obesity
    Isabelle Matias
    Group Endocannabinoids and Neuroadaptation, Institut National de la Sante et de la Recherche Medicale, Neurocentre Magendie, Physiophatologie de la Plasticité Neuronale, Bordeaux, France
    PLoS ONE 7:e42399. 2012
    ..Here we explored endocannabinoids and related N-acylethanolamines in saliva and verified their changes in relation to body weight status and in response to a meal or to body weight loss...
  4. pmc The role of hypothalamic mammalian target of rapamycin complex 1 signaling in diet-induced obesity
    Daniela Cota
    Department of Psychiatry, University of Cincinnati, Genome Research Institute, Cincinnati, Ohio 45237, USA
    J Neurosci 28:7202-8. 2008
    ..Overall, these findings point strongly to the possibility that reduced hypothalamic mTORC1 signaling contributes to the development of hyperphagia, weight gain, and leptin resistance during diet-induced obesity...
  5. doi request reprint Mammalian target of rapamycin complex 1 (mTORC1) signaling in energy balance and obesity
    Daniela Cota
    INSERM U862, Avenir group Physiopathology of Energy Balance and Obesity, Universite de Bordeaux 2, Bordeaux, France
    Physiol Behav 97:520-4. 2009
    ....
  6. doi request reprint Food intake-independent effects of CB1 antagonism on glucose and lipid metabolism
    Daniela Cota
    Department of Psychiatry, University of Cincinnati, Genome Research Institute, Cincinnati, Ohio, USA
    Obesity (Silver Spring) 17:1641-5. 2009
    ..These effects are independent of the anorectic action of the drug...
  7. doi request reprint Hypothalamic CB1 cannabinoid receptors regulate energy balance in mice
    Pierre Cardinal
    Group Energy Balance and Obesity, Institut National de la Sante et de la Recherche Medicale, Unite 862, Neurocentre Magendie, 146 rue Leo Saignat, F 33077 Bordeaux, France
    Endocrinology 153:4136-43. 2012
    ....
  8. pmc Fatty acid synthase inhibitors modulate energy balance via mammalian target of rapamycin complex 1 signaling in the central nervous system
    Karine Proulx
    Department of Psychiatry, University of Cincinnati, Genome Research Institute, Cincinnati, OH, USA
    Diabetes 57:3231-8. 2008
    ..The purpose of these experiments was to determine whether hypothalamic mTOR complex 1 (mTORC1) signaling is involved in mediating the effects of FAS inhibitors...
  9. doi request reprint Role of the endocannabinoid system in energy balance regulation and obesity
    Daniela Cota
    Department of Psychiatry, University of Cincinnati, Cincinnati, OH 45237, USA
    Front Horm Res 36:135-45. 2008
    ....
  10. doi request reprint Leucine supplementation modulates fuel substrates utilization and glucose metabolism in previously obese mice
    Elke Binder
    Neurocentre Magendie, INSERM, Physiopathologie de la Plasticité Neuronale, U862, Bordeaux, France NeuroCentre Magendie, Physiopathologie de la Plasticité Neuronale, Universite de Bordeaux, U862, Bordeaux, France
    Obesity (Silver Spring) 22:713-20. 2014
    ..Therefore, the impact of leucine supplementation on energy balance and associated metabolic changes in diet-induced obese (DIO) mice during and after weight loss was investigated...
  11. doi request reprint Regulation of food intake through hypothalamic signaling networks involving mTOR
    Stephen C Woods
    Department of Psychiatry, Genome Research Institute, University of Cincinnati, Cincinnati, Ohio 45237, USA
    Annu Rev Nutr 28:295-311. 2008
    ....
  12. doi request reprint Coupling nutrient sensing to metabolic homoeostasis: the role of the mammalian target of rapamycin complex 1 pathway
    Caroline Andre
    Group Energy Balance and Obesity, INSERM, Neurocentre Magendie, Physiophatologie de la Plasticité Neuronale, U862, F 33000 Bordeaux, France
    Proc Nutr Soc 71:502-10. 2012
    ....
  13. doi request reprint Bimodal control of stimulated food intake by the endocannabinoid system
    Luigi Bellocchio
    INSERM U862, Neurocentre Magendie, Endocannabinoids and Neuroadaptation, Bordeaux, France
    Nat Neurosci 13:281-3. 2010
    ..Conversely, brain CB(1) receptors modulating excitatory transmission mediated the well-known orexigenic effects of cannabinoids...
  14. ncbi request reprint The role of CNS fuel sensing in energy and glucose regulation
    Daniela Cota
    Department of Psychiatry, Genome Research Institute, University of Cincinnati, Cincinnati, Ohio 45237, USA
    Gastroenterology 132:2158-68. 2007
    ..The corollary to this hypothesis is that dysregulation of these fuel-sensing mechanisms in the brain may contribute to metabolic dysregulation underlying diseases, such as obesity and type 2 diabetes...
  15. ncbi request reprint Leptin in energy balance and reward: two faces of the same coin?
    Daniela Cota
    Department of Psychiatry, University of Cincinnati, Genome Research Institute, 2170 East Galbraith Road, Ohio 45237, USA
    Neuron 51:678-80. 2006
    ..In this issue of Neuron, Hommel et al. reveal a novel site for leptin's regulation of feeding. In turn, Fulton et al. propose a novel role for leptin in regulating non-feeding-related motivated behaviors...
  16. doi request reprint The role of the endocannabinoid system in the neuroendocrine regulation of energy balance
    Francisco Javier Bermudez-Silva
    INSERM U862, Avenir group Energy Balance and Obesity, Bordeaux, France
    J Psychopharmacol 26:114-24. 2012
    ..Thus, a perspective on new promising strategies to selectively target the ECS in the context of energy balance regulation is given...
  17. ncbi request reprint Mechanisms of oleoylethanolamide-induced changes in feeding behavior and motor activity
    Karine Proulx
    Genome Research Institute, ML 0506, University of Cincinnati, 2170 E Galbraith Road, Cincinnati, OH 45237, USA
    Am J Physiol Regul Integr Comp Physiol 289:R729-37. 2005
    ..Despite that OEA-induced anorexia is unlikely to be due to impaired motor activity, our data raise a cautionary note in how specific behavioral and metabolic effects of OEA should be interpreted...
  18. ncbi request reprint Cannabinoids, opioids and eating behavior: the molecular face of hedonism?
    Daniela Cota
    Obesity Research Center, Department of Psychiatry, University of Cincinnati Genome Research Institute, 2170 E Galbraith Road, Cincinnati, OH 45237, USA
    Brain Res Rev 51:85-107. 2006
    ....
  19. ncbi request reprint The integrative role of CNS fuel-sensing mechanisms in energy balance and glucose regulation
    Darleen Sandoval
    Department of Psychiatry, Genome Research Institute, University of Cincinnati, Cincinnati, OH 45237, USA
    Annu Rev Physiol 70:513-35. 2008
    ..Consequently, dysfunction of the ability of the CNS to integrate fuel-sensing signals may underlie the etiology of metabolic diseases such as obesity and diabetes...
  20. ncbi request reprint CB1 receptors: emerging evidence for central and peripheral mechanisms that regulate energy balance, metabolism, and cardiovascular health
    Daniela Cota
    Department of Psychiatry, Obesity Research Center, Genome Research Institute, University of Cincinnati, Cincinnati, OH 45237, USA
    Diabetes Metab Res Rev 23:507-17. 2007
    ..Thus, pharmacologic options targeting the ECS may provide a novel, effective approach to the prevention and management of CVD, type 2 diabetes and obesity...
  21. pmc The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis
    Daniela Cota
    Clinical Neuroendocrinology Group, Max Planck Institute of Psychiatry, Munich, Germany
    J Clin Invest 112:423-31. 2003
    ....
  22. ncbi request reprint The emerging role of the endocannabinoid system in endocrine regulation and energy balance
    Uberto Pagotto
    Endocrinology Unit, Department of Internal Medicine and Gastroenterology, Sant Orsola Malpighi Hospital, Bologna, Italy, and Department of Physiological Chemistry, Johannes Gutenberg University Mainz, Germany
    Endocr Rev 27:73-100. 2006
    ..The relevance of the system is further strenghtened by the notion that drugs interfering with the activity of the endocannabinoid system are considered as promising candidates for the treatment of various diseases, including obesity...
  23. ncbi request reprint Requirement of cannabinoid receptor type 1 for the basal modulation of hypothalamic-pituitary-adrenal axis function
    Daniela Cota
    Group of Clinical Neuroendocrinology, Max Planck Institute of Psychiatry, Munich, Germany
    Endocrinology 148:1574-81. 2007
    ....