Jacques Cosnes

Summary

Country: France

Publications

  1. pmc Misleading pustular plaques of the lower limbs during Crohn's disease: two case reports
    David Farhi
    AP HP, Hopital Tenon, Department of Dermatology, Paris F 75020, France
    J Med Case Reports 1:109. 2007
  2. ncbi request reprint Crohn's disease phenotype, prognosis, and long-term complications: what to expect?
    Jacques Cosnes
    Service de Gastroenterologie et Nutrition, Hôpital St Antoine et Université Pierre et Marie Curie, Paris
    Acta Gastroenterol Belg 71:303-7. 2008
  3. doi request reprint [Inflammatory bowel disease: from sulfasalazine to biologics]
    J Cosnes
    Service de Gastroenterologie et Nutrition, Hopital Saint Antoine, UPMC, Paris VI, 75571 Paris, France
    Gastroenterol Clin Biol 33:692-701. 2009
  4. doi request reprint Incidence of autoimmune diseases in celiac disease: protective effect of the gluten-free diet
    Jacques Cosnes
    Service de Gastroenterologie et Nutrition, Hôpital St Antoine and Université Pierre and Marie Curie, Paris, France
    Clin Gastroenterol Hepatol 6:753-8. 2008
  5. doi request reprint Epidemiology and natural history of inflammatory bowel diseases
    Jacques Cosnes
    Service de Gastroenterologie et Nutrition, Hôpital St Antoine and Pierre et Marie Curie University Paris VI, Paris, France
    Gastroenterology 140:1785-94. 2011
  6. doi request reprint Can we modulate the clinical course of inflammatory bowel diseases by our current treatment strategies?
    Jacques Cosnes
    Service de Gastroenterologie et Nutrition, Hôpital St Antoine et Université Pierre et Marie Curie Paris VI, Paris, France
    Dig Dis 27:516-21. 2009
  7. doi request reprint Smoking, physical activity, nutrition and lifestyle: environmental factors and their impact on IBD
    Jacques Cosnes
    Service de Gastroenterologie et Nutrition, Hopital St Antoine, Paris, France
    Dig Dis 28:411-7. 2010
  8. doi request reprint Lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease: a prospective observational cohort study
    Laurent Beaugerie
    Department of Gastroenterology, Assistance Publique Hopitaux de Paris AP HP, Hopital Saint Antoine, Universite Pierre et Marie Curie Paris VI, Paris, France
    Lancet 374:1617-25. 2009
  9. doi request reprint Usefulness of co-treatment with immunomodulators in patients with inflammatory bowel disease treated with scheduled infliximab maintenance therapy
    Harry Sokol
    Gastroenterology and Nutrition Department, Saint Antoine Hospital, AP HP, 184 rue du Faubourg Saint Antoine, Paris, France
    Gut 59:1363-8. 2010
  10. pmc Genotype/phenotype analyses for 53 Crohn's disease associated genetic polymorphisms
    Camille Jung
    Universite Paris Diderot, UMR843, Paris, France
    PLoS ONE 7:e52223. 2012

Detail Information

Publications46

  1. pmc Misleading pustular plaques of the lower limbs during Crohn's disease: two case reports
    David Farhi
    AP HP, Hopital Tenon, Department of Dermatology, Paris F 75020, France
    J Med Case Reports 1:109. 2007
    ..Cutaneous Crohn's disease is characterized by skin non-caseating epithelioid granulomatas with giant cells, remote from the gastrointestinal tract. We report herein two new cases...
  2. ncbi request reprint Crohn's disease phenotype, prognosis, and long-term complications: what to expect?
    Jacques Cosnes
    Service de Gastroenterologie et Nutrition, Hôpital St Antoine et Université Pierre et Marie Curie, Paris
    Acta Gastroenterol Belg 71:303-7. 2008
    ....
  3. doi request reprint [Inflammatory bowel disease: from sulfasalazine to biologics]
    J Cosnes
    Service de Gastroenterologie et Nutrition, Hopital Saint Antoine, UPMC, Paris VI, 75571 Paris, France
    Gastroenterol Clin Biol 33:692-701. 2009
    ..Moreover development of new therapeutic agents may permit to avoid surgery in patients who do not respond to therapy...
  4. doi request reprint Incidence of autoimmune diseases in celiac disease: protective effect of the gluten-free diet
    Jacques Cosnes
    Service de Gastroenterologie et Nutrition, Hôpital St Antoine and Université Pierre and Marie Curie, Paris, France
    Clin Gastroenterol Hepatol 6:753-8. 2008
    ..Celiac disease may be associated with autoimmune diseases. The aims of the present study were to determine in celiac patients which factors modulate the risk of autoimmune disease and to evaluate the effect of the gluten-free diet...
  5. doi request reprint Epidemiology and natural history of inflammatory bowel diseases
    Jacques Cosnes
    Service de Gastroenterologie et Nutrition, Hôpital St Antoine and Pierre et Marie Curie University Paris VI, Paris, France
    Gastroenterology 140:1785-94. 2011
    ..It has been proposed that only aggressive therapeutic approaches, based on treatment of early recurrent lesions in asymptomatic individuals, have a significant impact on progression of these chronic diseases...
  6. doi request reprint Can we modulate the clinical course of inflammatory bowel diseases by our current treatment strategies?
    Jacques Cosnes
    Service de Gastroenterologie et Nutrition, Hôpital St Antoine et Université Pierre et Marie Curie Paris VI, Paris, France
    Dig Dis 27:516-21. 2009
    ..There is the need in the next few years to better define these subgroups and to compare different strategies within each group through randomized interventional studies...
  7. doi request reprint Smoking, physical activity, nutrition and lifestyle: environmental factors and their impact on IBD
    Jacques Cosnes
    Service de Gastroenterologie et Nutrition, Hopital St Antoine, Paris, France
    Dig Dis 28:411-7. 2010
    ..In total, adhering to four simple lifestyle factors - never smoking, physical activity, prudent diet and body mass index <25 - may have a strong impact both on the prevention of major chronic diseases and on the course of IBD...
  8. doi request reprint Lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease: a prospective observational cohort study
    Laurent Beaugerie
    Department of Gastroenterology, Assistance Publique Hopitaux de Paris AP HP, Hopital Saint Antoine, Universite Pierre et Marie Curie Paris VI, Paris, France
    Lancet 374:1617-25. 2009
    ..Reports of an increased risk of lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease are controversial. We assessed this risk in a prospective observational cohort study...
  9. doi request reprint Usefulness of co-treatment with immunomodulators in patients with inflammatory bowel disease treated with scheduled infliximab maintenance therapy
    Harry Sokol
    Gastroenterology and Nutrition Department, Saint Antoine Hospital, AP HP, 184 rue du Faubourg Saint Antoine, Paris, France
    Gut 59:1363-8. 2010
    ..The aim of this study was to assess whether IS co-treatment is useful in patients with inflammatory bowel disease (IBD) on scheduled IFX infusions...
  10. pmc Genotype/phenotype analyses for 53 Crohn's disease associated genetic polymorphisms
    Camille Jung
    Universite Paris Diderot, UMR843, Paris, France
    PLoS ONE 7:e52223. 2012
    ..However, the impact of these associations in clinical practice remains to be defined. The aim of the study was to analyse the relationship between genotypes and phenotypes for the main 53 CD-associated polymorphisms...
  11. ncbi request reprint Predictive factors of response to cyclosporine in steroid-refractory ulcerative colitis
    Wulfran Cacheux
    Department of Gastroenterology, Assistance Publique des Hopitaux de Paris AP HP, Saint Antoine Hospital, Paris, France
    Am J Gastroenterol 103:637-42. 2008
    ..However, the individual's response to cyclosporine is poorly predictable. The aim of this study was to identify predictive factors of the response to cyclosporine in steroid-refractory UC...
  12. ncbi request reprint [Refractory proctitis]
    Philippe Seksik
    Service de Gastroenterologie et Nutrition, Hopital Saint Antoine, Paris, France
    Gastroenterol Clin Biol 31:393-7. 2007
  13. doi request reprint Risk factors for neoplasia in inflammatory bowel disease patients with pancolitis
    Vivianne Bergeron
    Service de Gastroenterologie et Nutrition, Hôpital Saint Antoine et Université Pierre et Marie Curie PARIS VI, Paris, France
    Am J Gastroenterol 105:2405-11. 2010
    ....
  14. ncbi request reprint Intestinal perforation in Crohn's disease. Factors predictive of surgical resection
    Hélène Brihier
    Service de Gastroentérologie et Nutrition et Service de Chirurgie, Hopital Saint Antoine, Paris
    Gastroenterol Clin Biol 29:1105-11. 2005
    ..New medical therapeutic options challenge the usual surgical management of Crohn's disease patients with intestinal perforation...
  15. doi request reprint Pregnancy outcome in patients with inflammatory bowel disease treated with thiopurines: cohort from the CESAME Study
    Jessica Coelho
    Department of Digestive Diseases, Lariboisiere Hospital, Paris, France
    Gut 60:198-203. 2011
    ..The aim of this study was to evaluate the pregnancy outcome of women with IBD who have been exposed to thiopurines...
  16. doi request reprint Predictive factors of eczema-like eruptions among patients without cutaneous psoriasis receiving infliximab: a cohort study of 92 patients
    Abdolrasool Esmailzadeh
    Department of Dermatology Allergology, Tenon Hospital, Paris, France
    Dermatology 219:263-7. 2009
    ..Anti-tumor-necrosis-factor-alpha agents are limited by their side effects. Eczema is one of the most frequent adverse reactions affecting quality of life...
  17. doi request reprint Incidence of nodular regenerative hyperplasia in inflammatory bowel disease patients treated with azathioprine
    Philippe Seksik
    Pierre and Marie Curie University, Faculte de Medecine, AP HP, Department of Gastroenterology and Nutrition, Hopital Saint Antoine, Paris, France
    Inflamm Bowel Dis 17:565-72. 2011
    ..The objective of this study was to evaluate the prevalence of NRH and its predictive factors in IBD patients treated with AZA...
  18. doi request reprint Significance of erythema nodosum and pyoderma gangrenosum in inflammatory bowel diseases: a cohort study of 2402 patients
    David Farhi
    Department of Dermatology, Hopital Tenon, AP HP, Paris, France
    Medicine (Baltimore) 87:281-93. 2008
    ..07). In conclusion, neither erythema nodosum nor pyoderma gangrenosum was significantly associated with the severity criteria in IBD; however, their occurrence may reflect a peculiar phenotype among affected patients...
  19. ncbi request reprint Prior appendectomy and the phenotype and course of Crohn's disease
    Jacques Cosnes
    Service de Gastroenterologie et Nutrition, Hopital St Antoine, 184 rue du Faubourg St Antoine, 75571 Paris Cedex 12, France
    World J Gastroenterol 12:1235-42. 2006
    ..To determine whether prior appendectomy modifies the phenotype and severity of Crohn's disease...
  20. doi request reprint Long-term outcome of patients with Crohn's disease who respond to azathioprine
    Marine Camus
    Department of Gastroenterology, Saint Antoine Hospital, Assistance Publique Hôpitaux de Paris and Paris VI University, Paris, France
    Clin Gastroenterol Hepatol 11:389-94. 2013
    ..Little is known about the long-term outcomes of patients with Crohn's disease (CD) who have a complete response to therapy with azathioprine. We assessed the long-term effects of azathioprine in responders...
  21. doi request reprint Overexpression of microRNAs-155 and 21 targeting mismatch repair proteins in inflammatory bowel diseases
    Magali Svrcek
    INSERM UMR S 938 Centre de Recherche Saint Antoine, Equipe Instabilité des Microsatellites et Cancers, Equipe Labellisée Ligue contre le Cancer, Paris, France
    Carcinogenesis 34:828-34. 2013
    ..The detection and monitoring of miR-155 field defect may, therefore, have implications for the prevention and treatment of MSI IBD CRCs...
  22. ncbi request reprint Epstein-Barr virus viral load in Crohn's disease: effect of immunosuppressive therapy
    Didier Reijasse
    Department of Gastroenterology, Saint Antoine University, Paris, France
    Inflamm Bowel Dis 10:85-90. 2004
    ..The aim of this work was to determine EBV-VL in patients with Crohn's disease (CD), both according to disease activity and use of immunosuppressive therapy, including infliximab...
  23. ncbi request reprint Predictive factors of response of perianal Crohn's disease to azathioprine or 6-mercaptopurine
    Thierry Lecomte
    Service de Gastroenterologie et Nutrition, Hopital Saint Antoine, Paris, France
    Dis Colon Rectum 46:1469-75. 2003
    ..This study was designed to evaluate the predictive factors of response of perianal Crohn's disease to azathioprine or 6-mercaptopurine...
  24. ncbi request reprint Gender differences in the response of colitis to smoking
    Jacques Cosnes
    Hopital Saint Antoine, 184 rue du Faubourg St Antoine, 75571 Paris Cedex 12, France
    Clin Gastroenterol Hepatol 2:41-8. 2004
    ..The aim of this study was to examine in parallel the effect of smoking on ulcerative colitis and Crohn's colitis and assess the effect of gender on the response of colitis to smoking...
  25. ncbi request reprint Predictors of Crohn's disease
    Laurent Beaugerie
    Department of Gastroenterology, Saint Antoine Hospital, and Pierre et Marie Curie University, Paris, France
    Gastroenterology 130:650-6. 2006
    ..Early intensive therapy in Crohn's disease should be considered only in patients with disabling disease. The aim of our study was to identify at diagnosis factors predictive of a subsequent 5-year disabling course...
  26. doi request reprint Risk factors associated with small bowel adenocarcinoma in Crohn's disease: a case-control study
    Gaël Piton
    Service de Gastroenterologie et Nutrition, Centre Hospitalier Universitaire de Besancon, France
    Am J Gastroenterol 103:1730-6. 2008
    ..It is well established that Crohn's disease (CD) is associated with an increased risk of small bowel adenocarcinoma (SBA). The data concerning SBA risk factors in CD are scanty. The aim of this study was to identify them...
  27. doi request reprint Acute cryptosporidiosis as a cause of sudden recurrence of digestive symptoms in patients with Crohn's disease
    Orianne Colussi
    Department of Gastroenterology and Nutrition, AP HP, Hôpital Saint Antoine F 75012 and UPMC Univ Paris 06 F 75005, Paris, France
    J Crohns Colitis 4:669-70. 2010
    ....
  28. ncbi request reprint [Undiagnosed celiac disease in childhood]
    Jacques Cosnes
    Service de Gastroenterologie et Nutrition, Hopital Rothschild, Paris, France
    Gastroenterol Clin Biol 26:616-23. 2002
    ..This study was designed to assess the proportion of adult patients with celiac disease who had had undiagnosed symptoms during childhood and to determine the consequences of such diagnostic delay...
  29. doi request reprint Current smoking differentially affects blood mononuclear cells from patients with Crohn's disease and ulcerative colitis: relevance to its adverse role in the disease
    Vivianne Bergeron
    INSERM ERL U1057, UMR 7203, Paris, France
    Inflamm Bowel Dis 18:1101-11. 2012
    ..To investigate this paradox, we evaluated the effect of cigarette smoke in the function of blood mononuclear cells from healthy subjects and patients with CD or UC in flare up...
  30. doi request reprint Effects of light smoking consumption on the clinical course of Crohn's disease
    Philippe Seksik
    Gastroenterology and Nutrition Department, Hôpital Saint Antoine and Université Pierre et Marie Curie, Paris VI, AP HP, Paris, France
    Inflamm Bowel Dis 15:734-41. 2009
    ..Cigarette smoking is associated with a more severe Crohn's disease (CD) course. However, the effect of light consumption is not known. Our aim was to characterize the effect of a light tobacco consumption on the course of CD...
  31. doi request reprint Natural history of Crohn's disease: comparison between childhood- and adult-onset disease
    Benedicte Pigneur
    gastroentérologie et nutrition pédiatrique, Hopital d Enfants Armand Trousseau, AP HP, Paris, France
    Inflamm Bowel Dis 16:953-61. 2010
    ..Childhood-onset Crohn's disease (CD) might reflect a more severe form of disease. To test this hypothesis we analyzed the long-term natural history of CD in an adult cohort of patients with childhood-onset compared to adult-onset CD...
  32. doi request reprint Methylation tolerance due to an O6-methylguanine DNA methyltransferase (MGMT) field defect in the colonic mucosa: an initiating step in the development of mismatch repair-deficient colorectal cancers
    Magali Svrcek
    Equipe Instabilité des Microsatellites et Cancers, Hopital Saint Antoine, Paris Cedex, France
    Gut 59:1516-26. 2010
    ..It was therefore hypothesised that an MGMT field defect may constitute a preneoplastic event for the development of MMR-deficient tumours displaying microsatellite instability (MSI)...
  33. ncbi request reprint Outcome of infants with celiac disease
    Jean Jacques Baudon
    Departement de Pediatrie, Hopital Saint Antoine, Paris
    Gastroenterol Clin Biol 29:1097-102. 2005
    ..Determine the proportion of infants whose celiac disease (CD) was confirmed in childhood and evaluate their prognosis in adulthood...
  34. ncbi request reprint Multidrug resistance gene-1 polymorphisms and resistance to cyclosporine A in patients with steroid resistant ulcerative colitis
    Fady Daniel
    Department of Gastroenterology, Assistance Publique des Hopitaux de Paris AP HP, Hopital Europeen Georges Pompidou, Paris, France
    Inflamm Bowel Dis 13:19-23. 2007
    ..This study aimed to establish whether multidrug resistance gene (MDR)1 polymorphisms would be associated with CsA failure...
  35. doi request reprint Connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel diseases
    Henri Duboc
    INSERM ERL U 1057, UMR7203, Paris, France
    Gut 62:531-9. 2013
    ..As dysbiosis has been reported in inflammatory bowel diseases (IBD), we aim to investigate the impact of IBD-associated dysbiosis on BA metabolism and its influence on the epithelial cell inflammation response...
  36. doi request reprint Presentation and long-term follow-up of refractory celiac disease: comparison of type I with type II
    Georgia Malamut
    Universite Paris Descartes, Paris, France
    Gastroenterology 136:81-90. 2009
    ..We compared the clinical and biological characteristics of RCD I and RCD II at diagnosis, the risk of developing an overt lymphoma, and the predictive factors of survival...
  37. pmc Development of the Crohn's disease digestive damage score, the Lémann score
    Benjamin Pariente
    Department of Hepatogastroenterology, Hopital Saint Louis, Paris, France
    Inflamm Bowel Dis 17:1415-22. 2011
    ..This instrument could be used to assess the effect of various medical therapies on the progression of bowel damage...
  38. ncbi request reprint Erythema nodosum-like eruption as a manifestation of azathioprine hypersensitivity in patients with inflammatory bowel disease
    Anne Laure de Fonclare
    Department of Dermatology, Hopital Tenon, Universite Pierre et Marie Curie, Paris, France
    Arch Dermatol 143:744-8. 2007
    ..Clinical manifestations of hypersensitivity to azathioprine may mimic symptoms of the initial disease. We report 5 cases of peculiar skin hypersensitivity reactions to azathioprine in patients with inflammatory bowel disease...
  39. ncbi request reprint Tobacco and IBD: relevance in the understanding of disease mechanisms and clinical practice
    Jacques Cosnes
    Service de Gastroenterologie et Nutrition, Hopital Saint Antoine, 184 rue du Faubourg Saint Antoine, 75571 Paris Cedex 12, France
    Best Pract Res Clin Gastroenterol 18:481-96. 2004
    ..A large amount of supportive information, use of nicotine-replacement therapies and antidepressants, and individual counselling might aid the patient in quitting...
  40. doi request reprint The enteropathy associated with common variable immunodeficiency: the delineated frontiers with celiac disease
    Georgia Malamut
    Universite Paris Descartes, France
    Am J Gastroenterol 105:2262-75. 2010
    ..We aimed to assess the clinical and histopathological features of the enteropathy associated with CVID...
  41. doi request reprint Azathioprine withdrawal in patients with Crohn's disease maintained on prolonged remission: a high risk of relapse
    Xavier Treton
    Hopital Beaujon, Pôle des Maladies de l Appareil Digestif, France
    Clin Gastroenterol Hepatol 7:80-5. 2009
    ....
  42. ncbi request reprint Long-term evolution of disease behavior of Crohn's disease
    Jacques Cosnes
    Service d hépatogastroentérologie et nutrition, Hopital Rothschild, Paris, France
    Inflamm Bowel Dis 8:244-50. 2002
    ..Our aim was to assess the long-term evolution of the disease behavior of CD and to determine the predictive factors and prognostic implications of this evolution...
  43. ncbi request reprint [Medical treatment of chronic radiation enteritis]
    Didier Reijasse
    service d hépato gastroentérologie et nutrition, Hopital Rothschild, Paris, France
    Gastroenterol Clin Biol 26:686-95. 2002
  44. ncbi request reprint [Mycophenolate mofetil in refractory Crohn's disease after failure of treatments by azathioprine or methotrexate]
    Samira Hafraoui
    Services d Hépato gastroentérologie, Hôpital Cl Huriez, Lille, Paris, France
    Gastroenterol Clin Biol 26:17-22. 2002
    ..Failure or intolerance of treatments by azathioprine (AZA) or methotrexate (MTX) is an important problem in the maintenance treatment of refractory CD. Results of the alternative use of mycophenolate mofetil (MMF) are conflicting...
  45. ncbi request reprint A nutritional support team in the pediatric intensive care unit: changes and factors impeding appropriate nutrition
    Cecile Lambe
    Réanimation Pédiatrique, Hopital Necker Enfants Malades, APHP, Universite Rene Descartes, Paris, France
    Clin Nutr 26:355-63. 2007
    ....
  46. ncbi request reprint Specific clinical and biological features characterize inflammatory bowel disease associated colorectal cancers showing microsatellite instability
    Magali Svrcek
    Assistance Publique Hopitaux de Paris AP HP, Hopital Saint Antoine, Service d Anatomie Pathologique, Paris, France
    J Clin Oncol 25:4231-8. 2007
    ..We investigated a large series of IBD-N for associations between MSI and several biologic and clinical parameters related to tumors, patients, and their treatment...