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Genomes and Genes | Eva ComperatSummaryCountry: France Publications
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Publications
Splenic metastases: clinicopathologic presentation, differential diagnosis, and pathogenesisEva Comperat
Service d Anatomie Pathologique, Hopital Pitie Salpetriere, Boulevard de l Hopital, 75013 Paris, France
Arch Pathol Lab Med 131:965-9. 2007..Splenic metastases occur in a context of multivisceral disseminated cancer or as a solitary lesion...
Different subtypes of carcinoma in situ of the bladder do not have a different prognosisEva Comperat
Department of Pathology, hôpital La Pitié Salpêtrière, Assistance Publique Hopitaux de Paris, Université Pierre et Marie Curie University Paris VI, 47 83, Bd de l Hopital, 75013 Paris, France
Virchows Arch 462:343-8. 2013..5955, respectively). Pathologists need not include different subtypes of primary CIS in their report as there is no difference in patient outcomes. It is important to recognize all different subtypes as CIS for best patient treatment...- Micropapillary urothelial carcinoma of the urinary bladder: a clinicopathological analysis of 72 casesEva Comperat
Service d Anatomie et Cytologie Pathologique et Service d Urologie, hôpital La Pitié Salpêtrière, Universite Pierre et Marie Curie, Paris, France
Pathology 42:650-4. 2010..It is unknown if any amount of a micropapillary component justifies the diagnosis of MPC. It is also unknown if surface MPC also has aggressive potential... - Aurora-A/STK-15 is differentially expressed in the micropapillary variant of bladder cancerEva Comperat
Service d anatomie et cytologie pathologique, hôpital La Pitié Salpêtrière, Paris, France
Urol Int 82:312-7. 2009..Our series explores protein expression of markers known to be indicators of poor clinical outcome and progression, trying to explain aggressiveness of MPC... - Oncological control after radical prostatectomy in men with clinical T3 prostate cancer: a single-centre experienceEvanguelos Xylinas
Department of Urology, GHU EST Pitié Tenon, Assistance Publique Hopitaux de Paris, Paris, France
BJU Int 103:1173-8; discussion 1178. 2009..To determine the effectiveness of cancer control afforded by radical prostatectomy (RP) in patients with clinical stage T3 prostate cancer... - Gene expression study of Aurora-A reveals implication during bladder carcinogenesis and increasing values in invasive urothelial cancerEva Comperat
CNRS UMR 8149, Faculte de Pharmacie, Paris V, Paris, France
Urology 72:873-7. 2008..We wanted to gain better insight into the early molecular mechanisms of bladder carcinogenesis by evaluating Aurora-A gene expression, which is implicated in genomic stability and essential for mitosis... - Clinical significance of intratumoral CD8+ regulatory T cells in prostate carcinomaEva Comperat
Pathologic Anatomy Service and Urology Service, hôpital La Pitié Salpêtrière, AP HP, Universite Pierre et Marie Curie, Parie, Frances
Anal Quant Cytol Histol 32:39-44. 2010..To explore Foxp3, a member of the forkhead box family of transcription factors, which is a major gene for regulatory T (Treg) cell development of CD4+CD25+ or CD8+CD25+ phenotype... - Full analysis of the prostatic urethra at the time of radical cystoprostatectomy for bladder cancer: impact on final disease stageJustine Varinot
Department of Pathology, Pitie Salpetriere Hospital, GHU Est, University PMC Paris VI, Paris, France
Virchows Arch 455:449-53. 2009..Data are similar to those published in the recent literature, where whole mount sections were used. This protocol also permits better detection of concomitant prostate carcinomas... - Tissue expression of IL16 in prostate cancer and its association with recurrence after radical prostatectomyEva Comperat
ER2, University PMC Paris VI, CeRePP, Paris, France
Prostate 70:1622-7. 2010..Genetic polymorphism located within the IL16 gene has been reported to be associated with aggressive prostate cancer (PCa). Our aim was to establish whether the tissue expression of IL16 is a prognostic factor of survival in PCa... - Impact of the expression of Aurora-A, p53, and MIB-1 on the prognosis of urothelial carcinomas of the upper urinary tractSylvia Scarpini
Academic Pathology Department, hôpital La Pitié Salpêtrière, Universite Pierre et Marie Curie, Paris, France
Urol Oncol 30:182-7. 2012..To investigate whether overexpression of p53, MIB-1, and Aurora-A on protein level played a role in the relapse of urothelial carcinomas of the upper urinary tract (UC-UUT)... - Comparison of mid-term carcinologic control obtained after open, laparoscopic, and robot-assisted radical prostatectomy for localized prostate cancerSarah J Drouin
Department of Urology, GHU Est, Assistance Publique Hopitaux de Paris, Faculte de Medecine Pierre et Marie Curie, Pitie Salpetriere Hospital, University Paris VI, Paris, France
World J Urol 27:599-605. 2009..To determine the cancer control afforded by radical prostatectomy in patients who underwent either an open, laparoscopic, or robotic procedure for localized prostate cancer... - Long-term outcomes after nephron sparing surgery for renal cell carcinoma larger than 4 cmMatthieu Peycelon
Department of Urology, Groupement Hospitalier Universitaire Est Pitié Tenon, Assistance Publique Hôpitaux de Paris and Faculté de Médecine Pierre et Marie Curie, University Paris VI, Paris, France
J Urol 181:35-41. 2009..We determined the cancer control provided by nephron sparing surgery for renal cell carcinoma greater than 4 cm... - Quantitative RT-PCR analysis of PSA and prostate-specific membrane antigen mRNA to detect circulating tumor cells improves recurrence-free survival nomogram prediction after radical prostatectomyDavid R Yates
Faculte de Medecine Pierre et Marie Curie, Academic Department of Urology of la Pitiè Salpétriére Hospital, Assistance Publique Hopitaux de Paris, University Paris VI, 75013 Paris, France
Prostate 72:1382-8. 2012.... - Oncologic control obtained after radical prostatectomy in men with a pathological Gleason score ≥ 8: a single-center experienceFrançois Audenet
The Academic Department of Urology, Pathology and Statistics of La Pitié Salpétrière, Groupe Hospitalo Universitaire EST, Assistance Publique Hopitaux de Paris, Paris, France
Urol Oncol 29:602-7. 2011..To assess the oncologic control afforded by radical prostatectomy (RP) in high-risk prostate cancers with a Gleason score ≥ 8... - Oncologic outcome after radical prostatectomy in men with PSA values above 20 ng/ml: a monocentric experienceKien Nguyen
Department of Urology of Pitié Salpétrière Hospital, GHU Est, Assistance Publique Hopitaux de Paris, Faculte de Medecine Pierre et Marie Curie, University Paris VI, 75013 Paris, France
World J Urol 27:653-8. 2009..To assess the cancer control afforded by radical prostatectomy (RP) in patients with prostate-specific antigen (PSA) values above 20 ng/ml... - Clinical characteristics and pathologic findings in patients eligible for active surveillance who underwent radical prostatectomySarah J Drouin
Department of Urology of GHU EST, Assistance Publique Hopitaux de Paris, Paris, France
Urol Oncol 30:402-7. 2012..To analyze clinical characteristics and pathologic findings in patients eligible for active surveillance (AS) who underwent radical prostatectomy (RP)... - p63 gene expression study and early bladder carcinogenesisEva Comperat
CNRS UMR 8149, Faculté de Pharmacie Paris V, Paris, France
Urology 70:459-62. 2007.... - Low accuracy of routine ultrasound-guided systematic 12-core biopsies in prostate tumor mappingOlivier Belas
Department of Urology, Pitie Salpetriere Hospital, GHU Est, Assistance Publique Hopitaux de Paris, Paris, France
Can J Urol 19:6366-72. 2012..To determine the accuracy of a 12-core biopsy protocol in assessing the location of prostate tumors within radical prostatectomy (RP) specimens... - Pathological findings and oncological control afforded by radical prostatectomy in men with high-risk prostate cancer: a single-centre studyAlexandra Masson-Lecomte
The Academic Department of Urology, Pathology and Statistics of La Pitié Salpétrière, Groupe Hospitalo Universitaire EST, Assistance Publique Hopitaux de Paris, 47 83 bvd de l hopital, 75013 Paris, France
World J Urol 29:665-70. 2011..To assess pathological findings and oncological control afforded by radical prostatectomy (RP) in high-risk prostate cancers (PCa) at our institution... - Oncologic control provided by HIFU therapy as single treatment in men with clinically localized prostate cancerVincent Misrai
Department of Urology of Pitié Salpétrière Hospital, Groupe Hospitalo Univeristaire EST, Assistance Publique Hôpitaux de Paris Faculté de Médecine Pierre et Marie Curie, University Paris VI, Paris, France
World J Urol 26:481-5. 2008..To assess the long term oncologic results of high-intensity focused ultrasound therapy (HIFU) as a primary and single treatment for clinically localized prostate cancer... - Persistently elevated prostate-specific antigen at six weeks after radical prostatectomy helps in early identification of patients who are likely to recurFrançois Audenet
The Academic Department of Urology, Pathology and Statistics of La Pitié Salpétrière, Groupe Hospitalo Universitaire EST, Assistance Publique Hopitaux de Paris, 47 83 bvd de l hopital, 75013 Paris, France
World J Urol 30:239-44. 2012..To determine the prognostic factors of biochemical recurrence in patients who failed to achieve an undetectable prostate-specific antigen (PSA) after radical prostatectomy (RP) for prostate cancer... - Genetic variability in 8q24 confers susceptibility to urothelial carcinoma of the upper urinary tract and is linked with patterns of disease aggressiveness at diagnosisMorgan Roupret
Academic Department of Urology and Pathology, Groupe Hospitalo Universitaire EST, Assistance Publique Hopitaux de Paris, Paris, France
J Urol 187:424-8. 2012..A polymorphism located at the T allele of rs9642880 on chromosome 8q24 is linked to an enhanced risk of bladder tumors. We explored the association of this polymorphism with susceptibility to upper urinary tract urothelial carcinoma... - Prostate cancer with clear cell features and an unusual nested-like pattern of growth: a case reportJustine Varinot
Public Assistance Hospital of Paris, Department of Pathology, La Pitie Salpetriere Hospital, University UPMC Paris VI, Paris, France
Anal Quant Cytol Histol 34:289-92. 2012..Clear cell carcinoma of the prostate is rare, with the majority of reports consisting of a single case study... - Mapping of transrectal ultrasonographic prostate biopsies: quality control and learning curve assessment by image processingPierre Mozer
Department of Urology, Assistance Publique Hopitaux de Paris, Paris, France
J Ultrasound Med 28:455-60. 2009.... - Prostate needle biopsy examination by means of virtual microscopyCyrus Chargari
Department of Oncology and Radiotherapy, Val de Grâce Hospital, Paris, France
Pathol Res Pract 207:366-9. 2011..23, marginal agreement) to 66.2% for virtual slide examination (κ=0.42, good agreement). Virtual microscopy does not compromise, but might improve, the accuracy of grading in prostate needle biopsies. This requires further assessment... - Molecular and histological markers in urothelial carcinomas of the upper urinary tractStephanie Eltz
Academic Department of Urology of la Pitié Salpêtrière and Tenon Hospital, Paris, France
BJU Int 102:532-5. 2008..Therefore a subgroup of patients with a higher risk of recurrence could be identified as well as patients that could benefit from minimal invasive surgery... - Genetic polymorphisms on 8q24.1 and 4p16.3 are not linked with urothelial carcinoma of the bladder in contrast to their association with aggressive upper urinary tract tumoursDavid R Yates
Academic Department of Urology and Pathology of la Pitié Salpêtrière, Tenon Hospital, Groupe Hospitalo Universitaire EST, Assistance Publique, Hopitaux de Paris, Faculte de Medecine Pierre et Marie Curie, University Paris VI, Paris, France
World J Urol 31:53-9. 2013..Herein, we evaluate a bladder-UC cohort to see whether similar polymorphisms are linked similarly same way with disease risk and aggressiveness... - The presence of detrusor muscle in the pathological specimen after transurethral resection of primary pT1 bladder tumors and its relationship to operator experienceMorgan Roupret
Department of Urology, Pitie Salpetriere Hospital, Assistance Publique Hopitaux de Paris, France
Can J Urol 19:6459-64. 2012..Accurate staging at the time of primary TURBT, including the presence of DM, is crucial to avoid understaging and unnecessary delay in definitive treatment... - Effect of genetic variability within 8q24 on aggressiveness patterns at diagnosis and familial status of prostate cancerOlivier Cussenot
CeRePP, Tenon Hospital, Paris, France
Clin Cancer Res 14:5635-9. 2008..Recently, two independent loci located at 8q24 that contribute to prostate cancer risk in men of European origin were identified... - Cross-cultural validation of a prognostic tool: example of the Kattan preoperative nomogram as a predictor of prostate cancer recurrence after radical prostatectomyMorgan Roupret
Department of Urology, Groupe Hospitalo Universitaire EST, Pitie Salpetriere, Paris, France
BJU Int 104:813-7; discussion 817-8. 2009..To establish the predictive accuracy of the Kattan preoperative nomogram by comparing predictions at 5 years with actual progression in patients who had a radical prostatectomy (RP)... - Poorer outcome in Polynesian patients with prostate cancer treated with definitive conformational radiation therapyAntonin Levy
Department of Radiation Oncology, Pitie Salpetriere University Hospital, Paris, France
Radiother Oncol 101:502-7. 2011..To compare freedom from biochemical failure (FFBF) of French Polynesian (FP) and Native European (NE) prostate cancer patients after definitive conformal radiotherapy (RT)... - Immunohistochemical expression of p63, p53 and MIB-1 in urinary bladder carcinoma. A tissue microarray study of 158 casesEva Comperat
Service Central d Anatomie et Cytologie Pathologiques et d Urologie, hôpital La Pitié Salpêtrière, 83, Bd de l Hopital, 75013 Paris, France
Virchows Arch 448:319-24. 2006..A statistical difference disserving pTa and pT1/>or=pT2 with a statistical significance (p<10(-6)) could also be observed. P63 should be considered as an additional biomarker that might help pathologists to classify their patients... - Upper urinary tract urothelial cell carcinomas and other urological malignancies involved in the hereditary nonpolyposis colorectal cancer (lynch syndrome) tumor spectrumMorgan Roupret
Hopital Pitie Salpetriere, Academic Urology Department, 47 83 boulevard de l Hopital, 75013 Paris, France
Eur Urol 54:1226-36. 2008..The data describing the urologic extracolonic cancers associated with hereditary nonpolyposis colorectal cancer (HNPCC) are variable... - Variable sensitivity and specificity of TTF-1 antibodies in lung metastatic adenocarcinoma of colorectal originEva Comperat
Service d Anatomopathologique de l Hôtel Dieu, Place du Parvis Notre Dame, Paris, France
Mod Pathol 18:1371-6. 2005..01). These results suggest that the diagnostic virtue of TTF-1 detection depends on the used antibody's clone. The SPT24 clone seems to have a stronger affinity for TTF-1 protein but may lead to a few positive colorectal adenocarcinomas... - An adult case of melanotic Xp11 translocation renal cancers: distinct entity or sub-entity?Justine Varinot
Service d Anatomie Pathologique, hôpital La Pitié Salpêtrière, Universite Pierre et Marie Curie, Paris, France
Int J Surg Pathol 19:285-9. 2011..The authors describe a pigmented renal tumor occurring in a 30-year-old woman with distinct morphology and immunohistochemical characteristics as Xp11 translocation renal cancer... - [Left paravesical cystic urothelial tumour: an exceptional case?]Stéphane Leroux
Service d Urologie, GH Pitié Salpétrière, Paris, France
Prog Urol 16:208-10. 2006..In view of the unusual histology, comprising carcinoma in situ and a transitional cell papillary tumour with metastatic lymph node extension, the authors reviewed the literature on this subject and identified only one similar case (5)... - [Bladder cancer in neurological patients: analysis of a single-centre series]Jérôme Parra
Services d urologie, Hopital Pitie Salpetriere, Paris, France
Prog Urol 17:1333-6. 2007..To report the prevalence, aetiologies and course of bladder cancer in our population of neurological patients... - Fluorescence diagnosis and flat lesions of urothelium: new challenges for pathologists and urologists (Review)Eva Comperat
Service d Anatomie Pathologique, hôpital La Pitié Salpêtrière, AP HP, Universite Pierre et Marie Curie, Paris VI, France
Oncol Rep 21:839-44. 2009..How far can we go in our answer as pathologists and how will it change the patient management?.. - [Can a standard treatment be proposed for penile cancer?]Jean Nicolas Cornu
Services d urologie, l Hôpital Pitie Salpêtrière, Paris, France
Prog Urol 17:1347-50. 2007..Malignant tumours of the penis are rare and their management is complex. The objective of this study was to review the management and report the results based on a personal series... - Concomitant Epstein-Barr virus-negative large B-cell lymphoma (Richter syndrome) and Epstein-Barr virus- positive B-cell lymphoproliferation after treatment with fludarabine and cyclophosphamide in a patient with B-cell chronic lymphocytic leukemiaEva Comperat
Service d Anatomie et de Cytologie Pathologiques, Hotel Dieu, Paris, France
Arch Pathol Lab Med 130:1227-30. 2006..The Epstein-Barr virus-positive lymphoproliferation can be accounted for by the type of immunosuppression induced by the treatment... - Histologic features in the urinary bladder wall affected from neurogenic overactivity--a comparison of inflammation, oedema and fibrosis with and without injection of botulinum toxin type AEva Comperat
Service d anatomie et cytologie pathologique, Hopital de la Pitie Salpetriere, Universite Paris VI, France
Eur Urol 50:1058-64. 2006..To study histological features and morphological differences in bladder wall specimen from patients with and without botulinum toxin A injections and to compare those issues in responders and non-responders to the toxin therapy... - Late recurrence of a prostatic adenocarcinoma as a solitary splenic metastasisEva Comperat
Service d anatomie et cytologie pathologique, Hopital La Pitie, Paris, France
Urol Int 78:86-8. 2007..This case suggests that splenic metastasis might be the result of the growth of an early blood-borne micrometastasis within the spleen after a period of clinical latency... - [Sensory innervation of the bladder: clinical and therapeutic implications]Eva Comperat
Service d anatomie et cytologie pathologique, Hopital de la Pitie Salpetriere, Faculte de Medecine Pierre et Marie Curie, Université Paris VI Paris, France
Prog Urol 17:5-11. 2007.... - Functional outcomes after management of end-stage neurological bladder dysfunction with ileal conduit in a multiple sclerosis population: a monocentric experienceGuillaume Legrand
Academic Department of Urology, Assistance Publique Hopitaux de Paris, University Paris VI, Paris, France
Urology 78:937-41. 2011..To assess the outcome of cutaneous noncontinent urinary diversion (CNCUD) for neurogenic bladder management in multiple sclerosis (MS) patients... - Bladder recurrence after surgery for upper urinary tract urothelial cell carcinoma: frequency, risk factors, and surveillanceMarie Dominique Azémar
Department of Urology, Pitié Salpêtrière and Tenon Hospitals, GHU Est, AP HP, Faculte de Medecine Pierre et Marie Curie, University Paris VI, Paris, France
Urol Oncol 29:130-6. 2011..To highlight the main risk factors for metachronous bladder recurrence after treatment of an upper urinary tract urothelial cell carcinomas (UUT-UCCs) based on the recent literature... - Patterns of bone marrow involvement in 58 patients presenting primary splenic marginal zone lymphoma with or without circulating villous lymphocytesJosee Audouin
Service central Jacques Delarue d Anatomie et de Cytologie Pathologiques, Hotel Dieu, Paris, France
Br J Haematol 122:404-12. 2003..Transformation into DLBCL occurred in 11 of 34 patients. The patterns described are not specific for PSMZL and occur also in primary nodal MZL and, more rarely, in MALT-type lymphoma... - Tumoural expression and circulating level of VEGFR-3 (Flt-4) in metastatic melanoma patients: correlation with clinical parameters and outcomeRoger Mouawad
AP HP, Salpetriere Hospital, University of Pierre and Marie Curie Paris 6, Laboratory of the Medical Oncology Department, 47 Boulevard de l Hopital, 75013 Paris, France
Eur J Cancer 45:1407-14. 2009.... - Expression of epidermal growth factor receptor and proliferative activity of cyst epithelium in human renal cystic diseasesEva Comperat
CNRS UMR 8149, and Service d Anatomie Pathologique, Centre Hospitalier Universitaire Bicêtre, Paris, France
Urol Int 76:269-73. 2006..EGF-r function and proliferative activity in cyst formation in PKD remains to be explored. EGF-r and Ki-67 expressions are not predictive of development of carcinoma in PKD... 
Renal angiomyolipoma associated with inferior vena cava thrombusXavier Durand
Department of Urology, Pitie Salpetriere University Hospital, 75013, Paris, France
Case Report Med 2009:789078. 2009..Intravascular extension into the IVC of angiomyolipoma has rarely been reported. We present a new case and reconsider the literature about this uncommon complication of a benign renal tumor...- Mucinous tubular and spindle cell carcinoma: a report of 15 cases and a review of the literatureSophie Ferlicot
Service d Anatomie Pathologique, Hopital de Bicetre, Paris, France
Virchows Arch 447:978-83. 2005..Further investigations are required to determine the frequency and true prognosis of these tumors, which are easily identifiable morphologically...