Research Topics
| E ComperatSummaryCountry: France Publications
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Detail Information
Publications
Patterns of bone marrow involvement in 58 patients presenting primary splenic marginal zone lymphoma with or without circulating villous lymphocytesJosee Audouin
Service central Jacques Delarue d Anatomie et de Cytologie Pathologiques, Hotel Dieu, Paris, France
Br J Haematol 122:404-12. 2003..Transformation into DLBCL occurred in 11 of 34 patients. The patterns described are not specific for PSMZL and occur also in primary nodal MZL and, more rarely, in MALT-type lymphoma...
[WHO classification 2004: tumors of the kidneys]E Comperat
Service d Anatomie Pathologique, hôpital La Pitié Salpêtrière, 83 bd de l hopital, 75013 Paris, France
J Radiol 87:1015-24. 2006..We also discuss the new concept of hybrid oncocytoma and chromophobe renal cell carcinoma, as well as the Birt-Hogg-Dube syndrome, which is associated with kidney tumors...
Prognostic value of MET, RON and histoprognostic factors for urothelial carcinoma in the upper urinary tractE Comperat
Unité Institut national de la santé et de la recherche médicale 03 37, Universite Pierre et Marie Curie, Paris, France
J Urol 179:868-72; discussion 872. 2008..We explored whether over expression of the 2 proteins has a role in the tumorigenesis and defined histoprognostic factors of poor clinical outcomes in patients with these tumors...
Molecular and histological markers in urothelial carcinomas of the upper urinary tractStephanie Eltz
Academic Department of Urology of la Pitié Salpêtrière and Tenon Hospital, Paris, France
BJU Int 102:532-5. 2008..Therefore a subgroup of patients with a higher risk of recurrence could be identified as well as patients that could benefit from minimal invasive surgery...
[Primary carcinoma of the head of the epididymis]F Thibault
Service d Urologie et de Transplantation Renale et Pancreatique, hôpital La Pitié Salpêtrière, 47, Boulevard de l Hopital, 75013 Paris, France
Prog Urol 19:66-8. 2009..Treatment is based on surgical resection, ideally via an inguinal incision, combined with chemotherapy adapted to the histological type...
[Urothelial carcinoma in patients under 40 years. Review of the cancer committee of the French Association of Urology]E Comperat
Service d Anatomie Pathologique, Universite Pierre et Marie Curie, groupe hospitalier Pitié Salpêtrière Paris VI, 47 83, Boulevard de l Hopital, 75013 Paris, France
Prog Urol 23:171-5. 2013..Urothelial carcinoma in young patients (<40 years) is rare. The only known risk factor is exposure to tobacco smoking and/or early active tobacco intoxication. No genetic predisposing factor seems to exist...
Expression of epidermal growth factor receptor and proliferative activity of cyst epithelium in human renal cystic diseasesEva Comperat
CNRS UMR 8149, and Service d Anatomie Pathologique, Centre Hospitalier Universitaire Bicêtre, Paris, France
Urol Int 76:269-73. 2006..EGF-r function and proliferative activity in cyst formation in PKD remains to be explored. EGF-r and Ki-67 expressions are not predictive of development of carcinoma in PKD...
Late recurrence of a prostatic adenocarcinoma as a solitary splenic metastasisEva Comperat
Service d anatomie et cytologie pathologique, Hopital La Pitie, Paris, France
Urol Int 78:86-8. 2007..This case suggests that splenic metastasis might be the result of the growth of an early blood-borne micrometastasis within the spleen after a period of clinical latency...
Concomitant Epstein-Barr virus-negative large B-cell lymphoma (Richter syndrome) and Epstein-Barr virus- positive B-cell lymphoproliferation after treatment with fludarabine and cyclophosphamide in a patient with B-cell chronic lymphocytic leukemiaEva Comperat
Service d Anatomie et de Cytologie Pathologiques, Hotel Dieu, Paris, France
Arch Pathol Lab Med 130:1227-30. 2006..The Epstein-Barr virus-positive lymphoproliferation can be accounted for by the type of immunosuppression induced by the treatment...
p63 gene expression study and early bladder carcinogenesisEva Comperat
CNRS UMR 8149, Faculté de Pharmacie Paris V, Paris, France
Urology 70:459-62. 2007....
Clinical significance of intratumoral CD8+ regulatory T cells in prostate carcinomaEva Comperat
Pathologic Anatomy Service and Urology Service, hôpital La Pitié Salpêtrière, AP HP, Universite Pierre et Marie Curie, Parie, Frances
Anal Quant Cytol Histol 32:39-44. 2010..To explore Foxp3, a member of the forkhead box family of transcription factors, which is a major gene for regulatory T (Treg) cell development of CD4+CD25+ or CD8+CD25+ phenotype...
Histologic features in the urinary bladder wall affected from neurogenic overactivity--a comparison of inflammation, oedema and fibrosis with and without injection of botulinum toxin type AEva Comperat
Service d anatomie et cytologie pathologique, Hopital de la Pitie Salpetriere, Universite Paris VI, France
Eur Urol 50:1058-64. 2006..To study histological features and morphological differences in bladder wall specimen from patients with and without botulinum toxin A injections and to compare those issues in responders and non-responders to the toxin therapy...
Immunohistochemical expression of p63, p53 and MIB-1 in urinary bladder carcinoma. A tissue microarray study of 158 casesEva Comperat
Service Central d Anatomie et Cytologie Pathologiques et d Urologie, hôpital La Pitié Salpêtrière, 83, Bd de l Hopital, 75013 Paris, France
Virchows Arch 448:319-24. 2006..A statistical difference disserving pTa and pT1/>or=pT2 with a statistical significance (p<10(-6)) could also be observed. P63 should be considered as an additional biomarker that might help pathologists to classify their patients...
Gene expression study of Aurora-A reveals implication during bladder carcinogenesis and increasing values in invasive urothelial cancerEva Comperat
CNRS UMR 8149, Faculte de Pharmacie, Paris V, Paris, France
Urology 72:873-7. 2008..We wanted to gain better insight into the early molecular mechanisms of bladder carcinogenesis by evaluating Aurora-A gene expression, which is implicated in genomic stability and essential for mitosis...
Splenic metastases: clinicopathologic presentation, differential diagnosis, and pathogenesisEva Comperat
Service d Anatomie Pathologique, Hopital Pitie Salpetriere, Boulevard de l Hopital, 75013 Paris, France
Arch Pathol Lab Med 131:965-9. 2007..Splenic metastases occur in a context of multivisceral disseminated cancer or as a solitary lesion...
Aurora-A/STK-15 is a predictive factor for recurrent behaviour in non-invasive bladder carcinoma: a study of 128 cases of non-invasive neoplasmsE Comperat
Service Central d Anatomie et Cytologie Pathologiques et d Urologie, hôpital La Pitié Salpêtrière, 83, Bd de l Hopital, 75013, Paris, France
Virchows Arch 450:419-24. 2007..03 in the NILGC group. Aurora-A is a more sensitive marker than MIB-1 to predict relapse in pTa bladder neoplasias. The combination of both markers seems to have a very powerful predictive value of recurrence (p<0.001)...
[Primary upper urinary tract tumors and subsequent location in the bladder]M D Azemar
Service d Urologie, Hopital de la Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Groupe Hospitalo Universitaire EST, Faculte de Medecine Pierre et Marie Curie, Universite Paris VI, Paris Cedex 13, France
Prog Urol 19:583-8. 2009..Surveillance protocol is based on cystoscopy and on urinary cytology during at least every three months for two years. Current surveillance regimen have a low level of evidence considering the paucity of UUT-UCC...
[Results of nephron-sparing surgery for renal cell carcinoma of more than 4 cm in diameter]M Peycelon
Service d urologie du GHU Est Pitié Tenon, Hopital Pitie Salpetriere, AP HP, Faculte de Medecine Pierre et Marie Curie, Universite Paris VI, 47 83, Boulevard de l Hopital, 75651 Paris Cedex 13, France
Prog Urol 19:69-74. 2009..Therefore, it is absolutely necessary to investigate thoroughly the vascularization of the tumour to avoid such complications with exhaustive and accurate preoperative imaging...
Oncological outcomes in patients undergoing radical nephrectomy and vena cava thrombectomy for renal cell carcinoma with venous extension: a single-centre experienceJ Parra
Department of Urology of GHU EST, Assistance Publique Hopitaux de Paris, Faculte de Medecine Pierre et Marie Curie, University of Paris VI, Paris, France
Eur J Surg Oncol 37:422-8. 2011..To report on the effectiveness of the surgical management of renal cell carcinoma (RCC) in patients with a neoplastic thrombus of the vena cava...
[Oncologic and functional outcomes after radical prostatectomy in T3 prostate cancer]E Xylinas
Services d urologie, Hopital de la Pitie Salpetriere, Hopital Tenon, Assistance Publique Hopitaux de Paris, Groupe Hospitalo Universitaire EST, Faculte de Medecine Pierre et Marie Curie, Universite Paris VI, Boulevard de l Hopital, Paris, France
Prog Urol 19:285-90. 2009..However, patients have to be warned that they may undergo complementary treatments during the postoperative course of the disease...
[Prognostic influence of prostate gland invasion by bladder tumour and/or prostate cancer in cystoprostatectomy specimen: a review]C M Champy
Service d Urologie, Faculte de Medecine Pierre et Marie Curie, Universite Paris VI, Hopital Pitie Salpetriere, Assistance Publique Hopitaux de Paris, 83, Boulevard de l Hopital, 75013 Paris, France
Prog Urol 23:165-70. 2013..The aim of the current study was to report the prognostic influence of PCa in patients who underwent a CPT for MIBC...
[Ductal adenocarcinoma, four years follow-up]A Dohan
Service d urologie et de transplantation rénale, Faculte de Medecine Pierre et Marie Curie, Hopital Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Paris V, 47 83, Boulevard de l Hopital, 75013 cedex 13, Paris, France
Prog Urol 18:1093-6. 2008..We report the case of a 78-year-old patient presenting a pure ductal adenocarcinoma of the prostate locally advanced, with a four years' follow-up. With this case, we report the principal aspects of the literature...
Peroperative frozen section analysis of TTF-1 antigen expressionS Camilleri-Broet
Service d Anatomie Pathologique et Unité de Chirurgie Thoracique, Hotel Dieu, 1, Place du Parvis Notre Dame, Cedex 75181, Paris, France
J Clin Pathol 57:98-100. 2004..However, if immunohistological analysis has not been performed before surgery, a peroperative frozen section may be insufficient to distinguish between a primary pulmonary tumour and a metastatic tumour...
[Neoadjuvant therapy for renal cancer]F Thibault
Service d Urologie, d oncologie médicale de radiologie et de pathologie, Hopital de la Pitie Salpetriere, Universite Pierre et Marie Curie, 47, Boulevard de l Hopital, 75013 Paris, France
Prog Urol 18:256-8. 2008..Radical nephrectomy was then performed. On histological evaluation, the primary renal tumour and, to a lesser degree, the lymph nodes were predominantly necrotic...
[Pathologic diagnosis and management of flat lesions of urothelium detected with aminolevulinic acid (Hexvix®)]E Comperat
Assistance Publique Hopitaux de Paris, service d anatomopathologie de la Pitié Salpêtrière, Faculte de Medecine Pierre et Marie Curie, Universite Paris VI, 47 83, Boulevard de l Hopital, 75013 Paris, France
Prog Urol 21:157-65. 2011..The aim of the study was to review the most important flat lesions, to demonstrate the difficulty of classifying several lesions, to introduce to urologists the new problems linked to FD and to suggest new models for accurate analysis...
TRAF4 overexpression is a common characteristic of human carcinomasS Camilleri-Broet
Institut National de la Sante et de la Recherche Medicale INSERM, Unité 255 d Immunologie Cellulaire et Clinique, Universite Pierre et Marie Curie Paris VI, Faculte de Medecine, Centre de Recherches Biomedicales des Cordeliers, Paris, France
Oncogene 26:142-7. 2007..Considering that TRAF4 is located at 17q11.2 in a region of amplification devoid of known oncogenes and is commonly overexpressed in cancer, our data support an oncogenic role for TRAF4...
[Histological features and principles of treating testicle tumors in the elderly subject]P Camparo
Service d Anatomie et Cytologie Pathologiques, Hopital Foch, 40, rue Worth, 92150 Suresnes, France
Prog Urol 19:S142-6. 2009..This particular histological profile must be in mind when considering the appropriate therapeutic approach of testis tumors in elderly. This work is based on data collected between 1990 to 2005 by the french pathologists of the GELU...
[Predictive value of the asymptomatic prostatic inflammation in the development of prostate cancer]B Molimard
Service d Urologie, HIA du Val de Grâce, 74, boulevard de Port Royal, 75005 Paris, France
Prog Urol 20:508-14. 2010..In prostate cancer (PCa) development, this question is still not completely elucidated. The aim of the study was to investigate, whether the presence of inflammation in the first series of prostate biopsies was a factor of risk...
Aurora-A/STK-15 is differentially expressed in the micropapillary variant of bladder cancerEva Comperat
Service d anatomie et cytologie pathologique, hôpital La Pitié Salpêtrière, Paris, France
Urol Int 82:312-7. 2009..Our series explores protein expression of markers known to be indicators of poor clinical outcome and progression, trying to explain aggressiveness of MPC...
Full analysis of the prostatic urethra at the time of radical cystoprostatectomy for bladder cancer: impact on final disease stageJustine Varinot
Department of Pathology, Pitie Salpetriere Hospital, GHU Est, University PMC Paris VI, Paris, France
Virchows Arch 455:449-53. 2009..Data are similar to those published in the recent literature, where whole mount sections were used. This protocol also permits better detection of concomitant prostate carcinomas...
Cross-cultural validation of a prognostic tool: example of the Kattan preoperative nomogram as a predictor of prostate cancer recurrence after radical prostatectomyMorgan Roupret
Department of Urology, Groupe Hospitalo Universitaire EST, Pitie Salpetriere, Paris, France
BJU Int 104:813-7; discussion 817-8. 2009..To establish the predictive accuracy of the Kattan preoperative nomogram by comparing predictions at 5 years with actual progression in patients who had a radical prostatectomy (RP)...
Oncological control after radical prostatectomy in men with clinical T3 prostate cancer: a single-centre experienceEvanguelos Xylinas
Department of Urology, GHU EST Pitié Tenon, Assistance Publique Hopitaux de Paris, Paris, France
BJU Int 103:1173-8; discussion 1178. 2009..To determine the effectiveness of cancer control afforded by radical prostatectomy (RP) in patients with clinical stage T3 prostate cancer...
Micropapillary urothelial carcinoma of the urinary bladder: a clinicopathological analysis of 72 casesEva Comperat
Service d Anatomie et Cytologie Pathologique et Service d Urologie, hôpital La Pitié Salpêtrière, Universite Pierre et Marie Curie, Paris, France
Pathology 42:650-4. 2010..It is unknown if any amount of a micropapillary component justifies the diagnosis of MPC. It is also unknown if surface MPC also has aggressive potential...
Tissue expression of IL16 in prostate cancer and its association with recurrence after radical prostatectomyEva Comperat
ER2, University PMC Paris VI, CeRePP, Paris, France
Prostate 70:1622-7. 2010..Genetic polymorphism located within the IL16 gene has been reported to be associated with aggressive prostate cancer (PCa). Our aim was to establish whether the tissue expression of IL16 is a prognostic factor of survival in PCa...
Histological classification of malignant renal tumours at a time of major diagnostic and therapeutic changesE Comperat
Department of Pathology, La Pitié Salpêtrière, UPMC Paris VI, 47 83, Boulevard de l Hopital, 75651 Paris Cedex 13, France
Diagn Interv Imaging 93:221-31. 2012..The stage and grade are applicable in the same way, regardless of the nature of the tumours; for a given group, they are the best prognostic factors...
[Crohn's disease presenting with colovesical fistula]P Simon
Service d urologie et de transplantation rénale, Hopital de la Pitie Salpetriere, AP HP, Groupe Hospitalo Universitaire EST, 47 83, Boulevard de l Hopital, 75651 Paris Cedex 13, France
Prog Urol 18:193-5. 2008..The authors report an unusual case of rectovesical fistula and discuss diagnosis and treatment of Crohn's urodigestive fistulas...
[Disorders of bladder compliance and neurogenic bladder]E Chartier-Kastler
Service d Urologie, GH Pitié Salpétrière, Universite Paris VI, France
Prog Urol 17:442-7. 2007....
Oncologic outcome after radical prostatectomy in men with PSA values above 20 ng/ml: a monocentric experienceKien Nguyen
Department of Urology of Pitié Salpétrière Hospital, GHU Est, Assistance Publique Hopitaux de Paris, Faculte de Medecine Pierre et Marie Curie, University Paris VI, 75013 Paris, France
World J Urol 27:653-8. 2009..To assess the cancer control afforded by radical prostatectomy (RP) in patients with prostate-specific antigen (PSA) values above 20 ng/ml...
Effect of genetic variability within 8q24 on aggressiveness patterns at diagnosis and familial status of prostate cancerOlivier Cussenot
CeRePP, Tenon Hospital, Paris, France
Clin Cancer Res 14:5635-9. 2008..Recently, two independent loci located at 8q24 that contribute to prostate cancer risk in men of European origin were identified...
Myeloid sarcoma: clinical and morphologic criteria useful for diagnosisJ Audouin
Service Jacques-Delarue d'Anatomie et de Cytologie Pathologiques, , Paris, France
Int J Surg Pathol 11:271-82. 2003..Patients with myeloid sarcomas should be treated in the same way as patients with acute myeloblastic leukemia. Disease progression and prognosis are similar for the two conditions...
Comparison of mid-term carcinologic control obtained after open, laparoscopic, and robot-assisted radical prostatectomy for localized prostate cancerSarah J Drouin
Department of Urology, GHU Est, Assistance Publique Hopitaux de Paris, Faculte de Medecine Pierre et Marie Curie, Pitie Salpetriere Hospital, University Paris VI, Paris, France
World J Urol 27:599-605. 2009..To determine the cancer control afforded by radical prostatectomy in patients who underwent either an open, laparoscopic, or robotic procedure for localized prostate cancer...
Mapping of transrectal ultrasonographic prostate biopsies: quality control and learning curve assessment by image processingPierre Mozer
Department of Urology, Assistance Publique Hopitaux de Paris, Paris, France
J Ultrasound Med 28:455-60. 2009....
Tumoural expression and circulating level of VEGFR-3 (Flt-4) in metastatic melanoma patients: correlation with clinical parameters and outcomeRoger Mouawad
AP HP, Salpetriere Hospital, University of Pierre and Marie Curie Paris 6, Laboratory of the Medical Oncology Department, 47 Boulevard de l Hopital, 75013 Paris, France
Eur J Cancer 45:1407-14. 2009....
Oncologic control provided by HIFU therapy as single treatment in men with clinically localized prostate cancerVincent Misrai
Department of Urology of Pitié Salpétrière Hospital, Groupe Hospitalo Univeristaire EST, Assistance Publique Hôpitaux de Paris Faculté de Médecine Pierre et Marie Curie, University Paris VI, Paris, France
World J Urol 26:481-5. 2008..To assess the long term oncologic results of high-intensity focused ultrasound therapy (HIFU) as a primary and single treatment for clinically localized prostate cancer...
Mucinous tubular and spindle cell carcinoma: a report of 15 cases and a review of the literatureSophie Ferlicot
Service d Anatomie Pathologique, Hopital de Bicetre, Paris, France
Virchows Arch 447:978-83. 2005..Further investigations are required to determine the frequency and true prognosis of these tumors, which are easily identifiable morphologically...
[Left paravesical cystic urothelial tumour: an exceptional case?]Stéphane Leroux
Service d Urologie, GH Pitié Salpétrière, Paris, France
Prog Urol 16:208-10. 2006..In view of the unusual histology, comprising carcinoma in situ and a transitional cell papillary tumour with metastatic lymph node extension, the authors reviewed the literature on this subject and identified only one similar case (5)...
Do repeat intradetrusor botulinum toxin type a injections yield valuable results? Clinical and urodynamic results after five injections in patients with neurogenic detrusor overactivityAndre Reitz
Department of Urology, Hopital de la Pitie Salpetriere, Universite Pierre et Marie Curie Paris VI, France
Eur Urol 52:1729-35. 2007..To study repeat intradetrusor botulinum toxin injections for the treatment of neurogenic detrusor overactivity in terms of safety and improvement of continence status and urodynamic parameters...
Upper urinary tract urothelial cell carcinomas and other urological malignancies involved in the hereditary nonpolyposis colorectal cancer (lynch syndrome) tumor spectrumMorgan Roupret
Hopital Pitie Salpetriere, Academic Urology Department, 47 83 boulevard de l Hopital, 75013 Paris, France
Eur Urol 54:1226-36. 2008..The data describing the urologic extracolonic cancers associated with hereditary nonpolyposis colorectal cancer (HNPCC) are variable...
