Ada Collura

Summary

Country: France

Publications

  1. doi request reprint Extensive characterization of sphere models established from colorectal cancer cell lines
    Ada Collura
    INSERM, UMRS_938, Centre de Recherche Saint Antoine, Equipe Instabilité des Microsatellites et Cancers, 75012, Paris, France
    Cell Mol Life Sci 70:729-42. 2013
  2. doi request reprint Abasic sites linked to dUTP incorporation in DNA are a major cause of spontaneous mutations in absence of base excision repair and Rad17-Mec3-Ddc1 (9-1-1) DNA damage checkpoint clamp in Saccharomyces cerevisiae
    Ada Collura
    CEA, IRCM, 18 route du Panorama, 92265 Fontenay aux Roses, France
    DNA Repair (Amst) 11:294-303. 2012
  3. doi request reprint Expression of a mutant HSP110 sensitizes colorectal cancer cells to chemotherapy and improves disease prognosis
    Coralie Dorard
    Institut National de la Sante et de la Recherche Medicale INSERM, Centre de Recherche Saint Antoine, Equipe Instabilité des Microsatellites et Cancers, Paris, France
    Nat Med 17:1283-9. 2011
  4. doi request reprint Lynch or not Lynch? Is that always a question?
    Chrystelle Colas
    INSERM, UMRS 938, Centre de Recherche Saint Antoine, Equipe Instabilité des Microsatellites et Cancers, Paris, France
    Adv Cancer Res 113:121-66. 2012
  5. doi request reprint Methylation tolerance due to an O6-methylguanine DNA methyltransferase (MGMT) field defect in the colonic mucosa: an initiating step in the development of mismatch repair-deficient colorectal cancers
    Magali Svrcek
    Equipe Instabilité des Microsatellites et Cancers, Hopital Saint Antoine, Paris Cedex, France
    Gut 59:1516-26. 2010
  6. pmc Microsatellite instability in colorectal cancer: time to stop hiding!
    Alex Duval
    Institut National de la Sante et de la Recherche Medicale INSERM, Centre de Recherche Saint Antoine, Equipe Instabilité des Microsatellites et Cancers, Paris, France
    Oncotarget 2:826-7. 2011

Collaborators

Detail Information

Publications6

  1. doi request reprint Extensive characterization of sphere models established from colorectal cancer cell lines
    Ada Collura
    INSERM, UMRS_938, Centre de Recherche Saint Antoine, Equipe Instabilité des Microsatellites et Cancers, 75012, Paris, France
    Cell Mol Life Sci 70:729-42. 2013
    ..In conclusion, CFS models derived from CRC cell lines possess interesting phenotypic features that may have clinical relevance for drug resistance and disease relapse...
  2. doi request reprint Abasic sites linked to dUTP incorporation in DNA are a major cause of spontaneous mutations in absence of base excision repair and Rad17-Mec3-Ddc1 (9-1-1) DNA damage checkpoint clamp in Saccharomyces cerevisiae
    Ada Collura
    CEA, IRCM, 18 route du Panorama, 92265 Fontenay aux Roses, France
    DNA Repair (Amst) 11:294-303. 2012
    ....
  3. doi request reprint Expression of a mutant HSP110 sensitizes colorectal cancer cells to chemotherapy and improves disease prognosis
    Coralie Dorard
    Institut National de la Sante et de la Recherche Medicale INSERM, Centre de Recherche Saint Antoine, Equipe Instabilité des Microsatellites et Cancers, Paris, France
    Nat Med 17:1283-9. 2011
    ..The survival and response to chemotherapy of subjects with MSI CRCs was associated with the tumor expression level of HSP110ΔE9. HSP110 may thus constitute a major determinant for both prognosis and treatment response in CRC...
  4. doi request reprint Lynch or not Lynch? Is that always a question?
    Chrystelle Colas
    INSERM, UMRS 938, Centre de Recherche Saint Antoine, Equipe Instabilité des Microsatellites et Cancers, Paris, France
    Adv Cancer Res 113:121-66. 2012
    ..LS tumors are therefore at the junction of inherited and MSI cases. We describe here the defining characteristics of LS tumors that differentiate them from inherited non-MSI tumors and from non-inherited MSI tumors...
  5. doi request reprint Methylation tolerance due to an O6-methylguanine DNA methyltransferase (MGMT) field defect in the colonic mucosa: an initiating step in the development of mismatch repair-deficient colorectal cancers
    Magali Svrcek
    Equipe Instabilité des Microsatellites et Cancers, Hopital Saint Antoine, Paris Cedex, France
    Gut 59:1516-26. 2010
    ..It was therefore hypothesised that an MGMT field defect may constitute a preneoplastic event for the development of MMR-deficient tumours displaying microsatellite instability (MSI)...
  6. pmc Microsatellite instability in colorectal cancer: time to stop hiding!
    Alex Duval
    Institut National de la Sante et de la Recherche Medicale INSERM, Centre de Recherche Saint Antoine, Equipe Instabilité des Microsatellites et Cancers, Paris, France
    Oncotarget 2:826-7. 2011
    ..Note worthily, HSP110DE9 is the first HSP mutant identified in a cancer so far. Developing inhibitors of HSP110 that mimic the anti-cancer chemosensitizing effect of HSP110DE9 is also a promising perspective...