Robert Cohen

Summary

Country: France

Publications

  1. doi request reprint [Antibiotic prophylaxis for ENT and ophtalmologic pediatric surgery]
    R Cohen
    Groupe de pathologie infectieuse pédiatrique de la Société française de pédiatrie Service de néonatalogie, Hopital Intercommunal de Creteil, 40 avenue de Verdun, 94010 Creteil Cedex, France Association clinique et thérapeutique infantile du Val de Marne ACTIV, 27 rue Inkermann, 94100 Saint Maur des Faussés, France Electronic address
    Arch Pediatr 20:S79-82. 2013
  2. doi request reprint [Rational and irrational of Azithromycin use]
    R Cohen
    Groupe de pathologie infectieuse pédiatrique de la Société française de pédiatrie Service de néonatalogie, Hopital Intercommunal de Creteil, 40 avenue de Verdun, 94010 Creteil Cedex, France Association clinique et thérapeutique infantile du Val de Marne ACTIV, 27 rue Inkermann, 94100 Saint Maur des Faussés, France Electronic address
    Arch Pediatr 20:S104-7. 2013
  3. ncbi request reprint Probiotics and prebiotics in preventing episodes of acute otitis media in high-risk children: a randomized, double-blind, placebo-controlled study
    Robert Cohen
    Association Clinique et Thérapeutique Infantile du Val de Marne, Paris, France
    Pediatr Infect Dis J 32:810-4. 2013
  4. doi request reprint [Escherichia coli, a pathogen under fire from the news]
    R Cohen
    Centre Hospitalier Intercommunal de Creteil, 40, avenue de Verdun, 94010 Creteil Cedex, France ACTIV Association Clinique et Thérapeutique Infantile du Val de Marne, 27, rue Inkermann, 94100 Saint Maur des Fossés, France Electronic address
    Arch Pediatr 19:S77-9. 2012
  5. doi request reprint [Plea for advancement of the age of vaccination against human papillomavirus in France: Position of the Pediatric Infections Pathology Group (GPIP) and the French Association of Ambulatory Pediatrics (AFPA)]
    R Cohen
    Centre Hospitalier Intercommunal de Creteil, 40, avenue de Verdun, 94010 Creteil Cedex, France
    Arch Pediatr 19:S145-9. 2012
  6. doi request reprint [Synthesis of management of urinary tract infections in children]
    R Cohen
    Centre Hospitalier Intercommunal de Creteil, 40, avenue de Verdun, 94010 Creteil Cedex, France
    Arch Pediatr 19:S124-8. 2012
  7. doi request reprint [Meningococcal vaccines: from polysaccharide to conjugate vaccines]
    R Cohen
    ACTIV Association Clinique et Thérapeutique Infantile du Val de Marne, ACTIV, 27 rue Inkermann, 94100 Saint Maur des Fossés, France
    Arch Pediatr 19:S61-4. 2012
  8. pmc Nasopharyngeal flora in children with acute otitis media before and after implementation of 7 valent pneumococcal conjugate vaccine in France
    Robert Cohen
    ACTIV, Association Clinique Thérapeutique Infantile du Val de Marne, 27 rue Inkermann, F94100 Saint Maur des Fossés, France
    BMC Infect Dis 12:52. 2012
  9. doi request reprint Impact of 13-valent pneumococcal conjugate vaccine on pneumococcal nasopharyngeal carriage in children with acute otitis media
    Robert Cohen
    ACTIV Association Clinique et Thérapeutique Infantile du Val de Marne, Paris, France
    Pediatr Infect Dis J 31:297-301. 2012
  10. ncbi request reprint [Pharmacokinetics and pharmacodynamics of antimicrobial therapy used in child osteoarticular infections]
    R Cohen
    Groupe de pathologie infectieuse pédiatrique de la Société française de pédiatrie, Hopital Armand Trousseau, 26 av Docteur Arnold Netter 75012 Paris, France
    Arch Pediatr 14:S122-7. 2007

Detail Information

Publications96

  1. doi request reprint [Antibiotic prophylaxis for ENT and ophtalmologic pediatric surgery]
    R Cohen
    Groupe de pathologie infectieuse pédiatrique de la Société française de pédiatrie Service de néonatalogie, Hopital Intercommunal de Creteil, 40 avenue de Verdun, 94010 Creteil Cedex, France Association clinique et thérapeutique infantile du Val de Marne ACTIV, 27 rue Inkermann, 94100 Saint Maur des Faussés, France Electronic address
    Arch Pediatr 20:S79-82. 2013
    ..For cataracts, prophylaxis by intracameral cefuroxime must supplant the antibiotic therapy. ..
  2. doi request reprint [Rational and irrational of Azithromycin use]
    R Cohen
    Groupe de pathologie infectieuse pédiatrique de la Société française de pédiatrie Service de néonatalogie, Hopital Intercommunal de Creteil, 40 avenue de Verdun, 94010 Creteil Cedex, France Association clinique et thérapeutique infantile du Val de Marne ACTIV, 27 rue Inkermann, 94100 Saint Maur des Faussés, France Electronic address
    Arch Pediatr 20:S104-7. 2013
    ..This should lead to only use AZM in situations where well-conducted clinical studies have demonstrated an indisputable superiority over standard treatment or placebo, and by limiting the number of patients treated. ..
  3. ncbi request reprint Probiotics and prebiotics in preventing episodes of acute otitis media in high-risk children: a randomized, double-blind, placebo-controlled study
    Robert Cohen
    Association Clinique et Thérapeutique Infantile du Val de Marne, Paris, France
    Pediatr Infect Dis J 32:810-4. 2013
    ..We aimed to determine whether follow-up formula supplemented with proB and preB could reduce the risk of acute otitis media (AOM)...
  4. doi request reprint [Escherichia coli, a pathogen under fire from the news]
    R Cohen
    Centre Hospitalier Intercommunal de Creteil, 40, avenue de Verdun, 94010 Creteil Cedex, France ACTIV Association Clinique et Thérapeutique Infantile du Val de Marne, 27, rue Inkermann, 94100 Saint Maur des Fossés, France Electronic address
    Arch Pediatr 19:S77-9. 2012
    ..coli family is the penem classe. The frequent use of penems promotes the emergence of strains resistant to carbapenems. Sparing carbapenems should be a clear objective for non life-threatening infections...
  5. doi request reprint [Plea for advancement of the age of vaccination against human papillomavirus in France: Position of the Pediatric Infections Pathology Group (GPIP) and the French Association of Ambulatory Pediatrics (AFPA)]
    R Cohen
    Centre Hospitalier Intercommunal de Creteil, 40, avenue de Verdun, 94010 Creteil Cedex, France
    Arch Pediatr 19:S145-9. 2012
    ....
  6. doi request reprint [Synthesis of management of urinary tract infections in children]
    R Cohen
    Centre Hospitalier Intercommunal de Creteil, 40, avenue de Verdun, 94010 Creteil Cedex, France
    Arch Pediatr 19:S124-8. 2012
    ....
  7. doi request reprint [Meningococcal vaccines: from polysaccharide to conjugate vaccines]
    R Cohen
    ACTIV Association Clinique et Thérapeutique Infantile du Val de Marne, ACTIV, 27 rue Inkermann, 94100 Saint Maur des Fossés, France
    Arch Pediatr 19:S61-4. 2012
    ..They must replace polysaccharide vaccines notably because of the risk of immunologic hypo-responsiveness...
  8. pmc Nasopharyngeal flora in children with acute otitis media before and after implementation of 7 valent pneumococcal conjugate vaccine in France
    Robert Cohen
    ACTIV, Association Clinique Thérapeutique Infantile du Val de Marne, 27 rue Inkermann, F94100 Saint Maur des Fossés, France
    BMC Infect Dis 12:52. 2012
    ..We aimed to compare the NP carriage rates in young children with acute otitis media (AOM) before and after PCV7 implementation in France...
  9. doi request reprint Impact of 13-valent pneumococcal conjugate vaccine on pneumococcal nasopharyngeal carriage in children with acute otitis media
    Robert Cohen
    ACTIV Association Clinique et Thérapeutique Infantile du Val de Marne, Paris, France
    Pediatr Infect Dis J 31:297-301. 2012
    ..This program was used in 2010-2011 to assess the effect of the implementation of PCV13 on PNP carriage in young children with AOM...
  10. ncbi request reprint [Pharmacokinetics and pharmacodynamics of antimicrobial therapy used in child osteoarticular infections]
    R Cohen
    Groupe de pathologie infectieuse pédiatrique de la Société française de pédiatrie, Hopital Armand Trousseau, 26 av Docteur Arnold Netter 75012 Paris, France
    Arch Pediatr 14:S122-7. 2007
    ..aureus strains are methicillin susceptible and dosages of cephalosporins are increased. Clindamycin is a very interesting alternative, if the strains are susceptible to macrolides...
  11. ncbi request reprint [Evaluation of impact of CRP rapid test in management of febrile children in ambulatory pediatric practice]
    R Cohen
    Service de Bacteriologie, Hopital Intercommunal de Creteil, 40, avenue de Verdun, 94000 Creteil, France
    Arch Pediatr 15:1126-32. 2008
    ..This study was performed to assess, in private practices, the impact of rapid CRP test compared to usual technique at the laboratory for the management of children with FWO...
  12. doi request reprint Pneumococcal conjugate vaccine does not influence Staphylococcus aureus carriage in young children with acute otitis media
    Robert Cohen
    Service de Microbiologie, Centre Hospitalier Intercommunal de Creteil, Creteil, France
    Clin Infect Dis 45:1583-7. 2007
    ..8.7% in nonvaccinated children). Furthermore, in children aged >1 year, the booster dose induces a sharp reduction in the carriage of vaccine serotypes of S. pneumoniae, without any change in S. aureus carriage...
  13. doi request reprint [Clinical implications of antibiotic pharmacokinetic-pharmacodynamic parameters]
    R Cohen
    Groupe de pathologie infectieuse pédiatrique de la Société française de pédiatrie, Hôpital Intercommunal de Créteil et Association Clinique et Thérapeutique Infantile du Val de Marne ACTIV, Creteil, France
    Arch Pediatr 15:S53-8. 2008
    ..Moreover, these PK/PD parameters are the cornerstone of pre-clinical development of antibiotics, the determination of dosage and for the establishment of breakpoints for classifying strains in the sensitive or resistant area...
  14. ncbi request reprint [Pharyngitis in children]
    Robert Cohen
    Service de Microbiologie, CHI Creteil, 94010 Creteil
    Rev Prat 57:1777-80, 1782-3. 2007
    ..i.d for 6 days), cefpodoxime proxetil (8 mg/kg/j b.i.d for 5 days), cefuroxime axetil (30 mg/kg/j b.i.d for 4 days)...
  15. ncbi request reprint Relationship between clinical signs and symptoms and nasopharyngeal flora in acute otitis media
    R Cohen
    Service de Microbiologie, Centre Hospitalier Intercommunal Créteil, Creteil, France
    Clin Microbiol Infect 12:679-82. 2006
    ..83, 95% CI 3.76-6.20) and negatively with fever (OR 0.69, 95% CI 0.56-0.86). Carriage of pneumococci was associated positively with fever (OR 1.32, 95% CI 1.08-1.63) and negatively with conjunctivitis (OR 0.50, 95% CI 0.40-0.63)...
  16. ncbi request reprint Approaches to reduce antibiotic resistance in the community
    Robert Cohen
    Department of Microbiology, Centre Hospitalier Intercommunal de Creteil, Creteil, France
    Pediatr Infect Dis J 25:977-80. 2006
    ..The combination of these approaches, particularly the reduction of antibiotic use and pneumococcal immunization, could be synergistic...
  17. ncbi request reprint [Impact of CRP rapid test in management of febrile children in paediatric emergency units of Ile-de-France]
    R Cohen
    Service de Bacteriologie, Hopital Intercommunal de Creteil, 40, avenue de Verdun, 94000 Creteil, France
    Arch Pediatr 13:1566-71. 2006
    ....
  18. ncbi request reprint Impact of pneumococcal conjugate vaccine and of reduction of antibiotic use on nasopharyngeal carriage of nonsusceptible pneumococci in children with acute otitis media
    Robert Cohen
    Service de Microbiologie, Centre Hospitalier Intercommunal de Creteil, Creteil, France
    Pediatr Infect Dis J 25:1001-7. 2006
    ..The implementation of widespread vaccination with the heptavalent pneumococcal conjugate vaccine (PCV7) and the reduction of inappropriate antibiotic use could help reduce antibiotic resistance...
  19. doi request reprint The need for prudent use of antibiotics and routine use of vaccines
    R Cohen
    Paediatric Infectious Diseases, Department of Microbiology, Centre Hospitalier Intercommunal de Creteil, Creteil, France
    Clin Microbiol Infect 15:21-3. 2009
    ..6%, while highly penicillin-resistant strains decreased from 15.6% to 1.1%; no new serotype emergence was observed. Implementation of PCV programmes should be accompanied by supportive education on restricting the use of antibiotics...
  20. doi request reprint Dynamic of pneumococcal nasopharyngeal carriage in children with acute otitis media following PCV7 introduction in France
    R Cohen
    Departement de Microbiologie, Centre Hospitalier Intercommunal de Creteil, Service de Microbiologie, 40 avenue de Verdun, 94 000 Creteil, France
    Vaccine 28:6114-21. 2010
    ..Most of the serotype 19A replacement was related to the clonal expansion of ST276 which was found to be the predominant ST among penicillin non-susceptible isolates...
  21. ncbi request reprint [Antipyocyanic antibiotic therapy. Principles and efficacy factors]
    R Cohen
    CHI Creteil, 40, avenue de Verdun, 94010 Creteil, France
    Arch Pediatr 13:S10-2. 2006
    ..The new mechanisms of pathogenicity or resistance (biofilm secretion, quorum sensing, hypermutator phenomenon) far from being opposed to the rules of prescription reinforce and complicate them...
  22. ncbi request reprint [Shorten treatment of in children severe osteomyelitis]
    R Cohen
    Groupe de pathologie infectieuse pédiatrique de la Société française de pédiatrie, Service de Microbiologie, Hopital Necker Enfants Malades, 149 rue de Sevres, 75743 Paris Cedex 15, France
    Arch Pediatr 14:S128-30. 2007
    ..However, this type of treatment should be considered only for oral drugs with good pharmacokinetics/pharmacodynamic parameters as clindamycin of some first generation cephalosporins...
  23. pmc Risk factors for serotype 19A carriage after introduction of 7-valent pneumococcal vaccination
    Robert Cohen
    Department of Microbiology, CHI Creteil, France
    BMC Infect Dis 11:95. 2011
    ..To determine factors potentially related to 19A nasopharyngeal (NP) carriage we analyzed data from an ongoing prospective French national surveillance study of pneumococcal NP carriage in young children...
  24. doi request reprint [Colimycin: an old antibiotic which has to be learnt to know]
    R Cohen
    Service de Pediatrie Generale, Hopital Intercommunal de Creteil, 40, avenue de Verdun, 94000 Creteil, France
    Arch Pediatr 17:S171-6. 2010
    ..Monotherapy is not recommended because it promotes rapid development of resistance. Because of low serum concentrations, very close to MICs of targeted bacteria, the dosages are necessarily high...
  25. doi request reprint Study of the acceptability of antibiotic syrups, suspensions, and oral solutions prescribed to pediatric outpatients
    Robert Cohen
    Laboratoire de Microbiologie, Hopital Intercommunal de Creteil, Creteil, France
    Eur J Pediatr 168:851-7. 2009
    ..Poor compliance increases the risk of therapeutic failures and the emergence of resistance...
  26. ncbi request reprint [Recurrent respiratory tract infections: how should we investigate and treat?]
    R Cohen
    Laboratoire de Microbiologie, Hopital Intercommunal de Creteil, 40 avenue de Verdun, 94000 Creteil, France
    Arch Pediatr 12:183-90. 2005
    ..This paper presents the thought of an expert group trying to define the situations where biological tests or treatments are useful...
  27. ncbi request reprint Current approaches to otitis media
    R Cohen
    Department of Pediatrics, Intercommunal Hospital, Creteil, France
    Curr Opin Infect Dis 14:337-42. 2001
    ....
  28. ncbi request reprint Defining the optimum treatment regimen for azithromycin in acute tonsillopharyngitis
    Robert Cohen
    Centre Hospitalier Intercommunal de Creteil, Creteil, France
    Pediatr Infect Dis J 23:S129-34. 2004
    ....
  29. ncbi request reprint Evaluation of streptococcal clinical scores, rapid antigen detection tests and cultures for childhood pharyngitis
    Robert Cohen
    Department of Microbiology, Centre Hospitalier Intercommunal de Creteil, 94010 Creteil Cedex, France
    Eur J Pediatr 163:281-2. 2004
  30. ncbi request reprint [Child acute otitis media]
    Robert Cohen
    Service de Microbiologie, CHI Creteil, 94010 Creteil
    Rev Prat 57:1791-5. 2007
    ....
  31. ncbi request reprint [How to prescribe fewer antibiotics in children?]
    Robert Cohen
    Service de Microbiologie, Centre Hospitalier Intercommunal de Creteil, 94010 Creteil
    Rev Prat 53:1561-5. 2003
    ....
  32. ncbi request reprint Five vs. ten days of antibiotic therapy for acute otitis media in young children
    R Cohen
    Department of Microbiology and Pediatrics, Intercommunal Hospital of Creteil, France
    Pediatr Infect Dis J 19:458-63. 2000
    ..However, doubt persists regarding children younger than 2 years, and some authors therefore restrict short course therapy to children older than 2 years...
  33. ncbi request reprint One dose ceftriaxone vs. ten days of amoxicillin/clavulanate therapy for acute otitis media: clinical efficacy and change in nasopharyngeal flora
    R Cohen
    Department of Microbiology and Pediatrics, Intercommunal Hospital of Creteil, France
    Pediatr Infect Dis J 18:403-9. 1999
    ....
  34. ncbi request reprint [Utilization of rapid diagnostic tests for group A streptococcus and and bacteriologic and clinical correlations with acute angina in general medicine]
    R Cohen
    Laboratoire ASTRA, CHI Creteil
    Presse Med 27:1131-4. 1998
    ....
  35. ncbi request reprint Resistance trends in Streptococcus pyogenes (PROTEKT years 1-3 [1999-2002])
    R Cohen
    Intercommunal Hospital of Creteil, 40, avenue de Verdun, 94010 Creteil, France
    J Chemother 16:71-82. 2004
  36. ncbi request reprint Clinical efficacy of cefpodoxime in respiratory tract infection
    Robert Cohen
    Department of Microbiology, Intercommunal Hospital of Creteil, Creteil, France
    J Antimicrob Chemother 50:23-7. 2002
    ....
  37. ncbi request reprint Variables influencing bacteriological outcome in patients with streptococcal tonsillopharyngitis treated with penicillin V
    Philippe Ovetchkine
    Department of Paediatrics, Créteil Hospital, Paris, France
    Eur J Pediatr 161:365-7. 2002
    ..The rate of failure was statistically more important for children younger than 6 years (35.5%, 95% CI 29.9--41.1) than for older children (21.9%, 95% CI 16.9-26.9)...
  38. ncbi request reprint Comparison of two dosages of azithromycin for three days versus penicillin V for ten days in acute group A streptococcal tonsillopharyngitis
    Robert Cohen
    Association Clinique et Thérapeutique Infantile du Val de Marne, Paris, France
    Pediatr Infect Dis J 21:297-303. 2002
    ..This study investigates the efficacy and tolerability of two dosages of 3-day azithromycin (20 mg/kg/day and 10 mg/kg/day) compared with 10-day penicillin V...
  39. doi request reprint Decline in macrolide-resistant Streptococcus pyogenes isolates from French children
    Camille d'Humières
    Laboratoire d études de génétique bactérienne dans les infections de l enfant EA3105, Universite Denis Diderot Paris 7, Service de Microbiologie, Hopital Robert Debre, 75019 Paris, France
    Int J Med Microbiol 302:300-3. 2012
    ..6% erm(B). The 19 isolates included 7 different emm types (4, 1, 11, 2, 28, 12, and 77) and 7 corresponding multilocus sequence types. The current fall in macrolide consumption has led to a very low rate of GAS macrolide resistance...
  40. pmc Emergence of macrolide-resistant Streptococcus pyogenes strains in French children
    Edouard Bingen
    Universite Denis Diderot Paris 7, Service de Microbiologie, Hopital Robert Debre, 48 Bd Serurier, 75019 Paris, France
    Antimicrob Agents Chemother 48:3559-62. 2004
    ..A total of 22.4% were erythromycin resistant, and 69.4, 4.2, and 26.4% of these isolates harbored ermB, ermA, and mefA, respectively. Increasing resistance in France is mainly associated with a few emm type 28 clones...
  41. doi request reprint Rapid-antigen detection tests for group a streptococcal pharyngitis: revisiting false-positive results using polymerase chain reaction testing
    Jérémie F Cohen
    INSERM, UMR S953, Epidemiological Research Unit on Perinatal Health and Women s and Children s Health, Paris, France
    J Pediatr 162:1282-4, 1284.e1. 2013
    ..Finding that 61% of GAS culture-negative but RADT-positive cases were positive on both GAS polymerase chain reaction and Staphylococcus aureus testing, we posit bacterial inhibition as causative...
  42. pmc Population snapshot of Streptococcus pneumoniae serotype 19A isolates before and after introduction of seven-valent pneumococcal Vaccination for French children
    Farah Mahjoub-Messai
    Service de Microbiologie, Hôpital Robert Debré APHP, 75019 Paris, France
    J Clin Microbiol 47:837-40. 2009
    ..By applying multilocus sequence typing to 144 serotype 19A isolates collected before and after beginning PCV7 vaccination, we detected clonal expansion of the preexisting penicillin-intermediate sequence type 276...
  43. doi request reprint Invasive serogroup w meningococcal disease in children: a national survey from 2001 to 2008 in France
    Jean Gaschignard
    Hopital Robert Debre, Assistance Publique des Hopitaux de Paris, 49 boulevard Serrurier, Paris, France
    Pediatr Infect Dis J 32:798-800. 2013
    ..Isolates of the clonal complex sequence type-22 were associated with nonmeningeal presentation. Further investigations of clinical tropism of meningococcal W isolates are warranted. ..
  44. doi request reprint Association of meningococcal phenotypes and genotypes with clinical characteristics and mortality of meningitis in children
    Corinne Levy
    Groupe de Pathologie Infectieuse Pédiatrique, Société Française de Pédiatrie, Paris, France
    Pediatr Infect Dis J 29:618-23. 2010
    ....
  45. pmc Spectrum and inoculum size effect of a rapid antigen detection test for group A streptococcus in children with pharyngitis
    Jérémie F Cohen
    Unité de Recherche Epidémiologique en Santé Périnatale et Santé des Femmes et des Enfants U953, INSERM, Paris, France
    PLoS ONE 7:e39085. 2012
    ..We aimed to assess whether the performance of a rapid antigen detection test (RADT) for group A streptococcus (GAS) is affected by the clinical spectrum and/or bacterial inoculum size...
  46. doi request reprint Sensitivity of the bacterial meningitis score in 889 children with bacterial meningitis
    Francois Dubos
    Clinical Epidemiology Unit, Department of Pediatrics, Saint Vincent de Paul Hospital, AP HP and Paris Descartes University, Paris, France
    J Pediatr 152:378-82. 2008
    ..To validate sensitivity of the bacterial meningitis score (BMS) in a large population of children with bacterial meningitis (BM)...
  47. doi request reprint [Osteoarticular infections: therapeutic proposals of the Paediatric Infectious Diseases Group of the French Society of Paediatrics (GPIP)]
    E Grimprel
    Groupe de pathologie infectieuse pédiatrique de la Société française de pédiatrie, Hopital Armand Trousseau, 26 av Dr Arnold Netter 75012 Paris, Universite Pierre et Marie Curie Paris VI, France
    Arch Pediatr 15:S74-80. 2008
    ....
  48. doi request reprint [Bacteriology of cutaneous infections of the child]
    J Raymond
    Service de Bacteriologie, Hopital Cochin, 27 rue du Faubourg Saint Jacques, 75679 Paris cedex 19, France
    Arch Pediatr 15:S59-61. 2008
    ..In France, the incidence of methicillin resistant community acquired S. aureus strains is currently low, around 6 %, but the risk of a rapid increase is real...
  49. pmc Food intake during the previous 24 h as a percentage of usual intake: a marker of hypoxia in infants with bronchiolitis: an observational, prospective, multicenter study
    François Corrard
    ACTIV Association Clinique et Thérapeutique Infantile du Val de Marne, Saint Maur des Fossés, France
    BMC Pediatr 13:6. 2013
    ....
  50. ncbi request reprint PneumococcaL meningitis in french children before and after the introduction of pneumococcal conjugate vaccine
    Corinne Levy
    GPIP Groupe de Pathologie Infectieuse Pe diatrique de la SFP Socie te Franc aise de Pe diatrie, Paris, France
    Pediatr Infect Dis J 30:168-70. 2011
    ..3 (median 0.8) to 3.8 (median 1.5) years. After pneumococcal conjugate vaccine 7 implementation, a wide diversity of serotypes implicated in pneumococcalmeningitis was observed; serotypes 19A and 7F were the most frequent...
  51. ncbi request reprint Shortened course of antibacterial therapy for acute otitis media
    Philippe Ovetchkine
    Department of Pediatrics, Jean Verdier Hospital, Bondy, France
    Paediatr Drugs 5:133-40. 2003
    ..Reasons for a poorer efficacy in these groups of children are still not completely understood...
  52. ncbi request reprint Change in nasopharyngeal carriage of Streptococcus pneumoniae resulting from antibiotic therapy for acute otitis media in children
    R Cohen
    Microbiology Laboratory, CHI, Creteil, France
    Pediatr Infect Dis J 16:555-60. 1997
    ..The increase in antibiotic resistance of Streptococcus pneumoniae is generally attributed to the extensive use of antibiotics and the selective pressure on the bacterial strains of the nasopharyngeal flora...
  53. doi request reprint Pathogens implicated in acute otitis media failures after 7-valent pneumococcal conjugate vaccine implementation in France: distribution, serotypes, and resistance levels
    Vincent Couloigner
    Service d ORL Pédiatrique, Necker Hospital, AP HP, Universite Paris 5, Paris, France
    Pediatr Infect Dis J 31:154-8. 2012
    ..The causative pathogens were Streptococcus pneumoniae (Sp) followed by nontypable Haemophilus influenzae (NTHi). The aim of this study was to describe the epidemiology of pathogens involved in AOM treatment failures or recurrences...
  54. ncbi request reprint Bacterial meningitis in children: a French prospective study
    Edouard Bingen
    Service de Microbiologie EA3105, Hopital Robert Debre, Paris, France
    Clin Infect Dis 41:1059-63. 2005
    ..7%). Approximately one-half of S. pneumoniae isolates had diminished susceptibility to penicillin. The case-fatality rates were 7.6% for children with N. meningitidis meningitis and 10.8% for children with S. pneumoniae infection...
  55. pmc Emergence of group A streptococcus strains with different mechanisms of macrolide resistance
    Edouard Bingen
    Service de Microbiologie, Hopital Robert Debre, Paris, France
    Antimicrob Agents Chemother 46:1199-203. 2002
    ..In the two remaining posttreatment strains, the mechanisms of macrolide resistance could not be elucidated...
  56. ncbi request reprint Pneumococcal meningitis in the era of pneumococcal conjugate vaccine implementation
    E Bingen
    Service de Microbiologie, Hopital Robert Debre, 48 Bvd Serurier, F75019 Paris, France
    Eur J Clin Microbiol Infect Dis 27:191-9. 2008
    ..This study provides data on underlying conditions, penicillin susceptibility, serotype evolution according to vaccination status and risk factors for mortality for pneumococcal meningitis in children from 2001-2005 in France...
  57. doi request reprint Corticosteroid therapy in genotype ST-11 meningococcal infections
    Fouad Madhi
    Service de Pediatrie, Centre Hospitalier Intercommunal, Paris, France
    Pediatr Infect Dis J 32:291-3. 2013
    ..Genotypes of meningococcal isolates should be considered with corticosteroids therapy for meningococcal disease...
  58. pmc Community faecal carriage of extended-spectrum beta-lactamase-producing Enterobacteriaceae in French children
    André Birgy
    Laboratoire associé au Centre National de Référence Escherichia coli et Shigelles, Service de Microbiologie, Hôpital Robert Debré AP HP, Universite Denis Diderot, Sorbonne, Paris Cité, Paris, F 75505, France
    BMC Infect Dis 12:315. 2012
    ..Because intestinal carriage is a key factor in the epidemiology of ESBL-producing Enterobacteriaceae, the study of the prevalence of these resistant bacteria and risk factors in young children is of particular interest...
  59. ncbi request reprint Halofantrine efficacy in non-immune children with imported acute Plasmodium falciparum malaria Infection
    Isabelle Hau
    Service de Pediatrie, Centre Hospitalier Intercommunal de Creteil, 94000 Creteil, France
    Eur J Pediatr 163:22-4. 2004
    ..05). Moreover, diarrhoea was more frequently associated with relapses (P<0.04). Age and diarrhoea were significant independent factors contributing to relapses...
  60. ncbi request reprint [An open randomized trial, Pediazole versus cefaclor in the treatment of acute otitis media in children]
    R Cohen
    Service de Microbiologie, Hopital Intercommunal de Creteil
    Ann Pediatr (Paris) 38:115-9. 1991
    ..Tolerance was satisfactory in both groups. Clinical results were as follows: failures before or at completion of the course, 5/52 in the ES group versus 13/51 in the cefaclor for the treatment of children with acute otitis media...
  61. ncbi request reprint Characteristics and outcomes of acute otitis media in children carrying streptococcus pneumoniae or haemophilus influenzae in their nasopharynx as a single otopathogen after introduction of the heptavalent pneumococcal conjugate vaccine
    Laurence Caeymaex
    From the Clinical Research Centre CRC, Centre Hospitalier Intercommunal Créteil, France Service de Médecine néonatale, Centre Hospitalier Intercommunal Créteil, France National Reference Center for Pneumococci, AP HP, Hopital Europeen Georges Pompidou, Universite Paris 5, Paris Association Clinique et Thérapeutique Infantile du Val de Marne ACTIV, Saint Maur des Fossés Association Française de Pédiatrie Ambulatoire, Gradignan and Service de Microbiologie, Hôpital Robert Debré AP HP, Universite Paris Diderot, Paris, France
    Pediatr Infect Dis J 33:533-6. 2014
    ..5; 95% confidence interval: 0.36-0.83) and recurrence (odds ratio = 0.4; 95% confidence interval: 0.22-0.75). Post-PCV7 serotype replacement seemed not to affect the acute otitis media characteristics in these children. ..
  62. ncbi request reprint Epidemiologic study of conjunctivitis-otitis syndrome
    Edouard Bingen
    Service de Microbiologie, Hopital Robert Debre, Paris, France
    Pediatr Infect Dis J 24:731-2. 2005
    ..Pulsed field gel electrophoresis analysis of paired H. influenzae isolates from the conjunctival exudate and middle ear fluid of 21 patients showed identical strains in each patient...
  63. doi request reprint [Serotype 19F pneumococcal meningitis in an imunocompetent infant immunized with heptavalent pneumococcal conjugated vaccine Prevenar]
    A Isapof
    Service de Pediatrie, CHI de Créteil, 40, avenue de Verdun, 94000 Creteil, France
    Arch Pediatr 16:1133-6. 2009
    ..Seven cases of pneumococcal meningitis caused by serotypes covered by the available vaccine occurred in France in vaccinated children, 4 of which were caused by serotype 19F...
  64. ncbi request reprint [Epidemiology and physiopathology of osteoarticular infections in children (newborns except)]
    E Grimprel
    Groupe de pathologie infectieuse pédiatrique de la Société française de pédiatrie, Hopital Armand Trousseau, 26 av Docteur Arnold Netter, 75012 Paris France
    Arch Pediatr 14:S81-5. 2007
    ....
  65. ncbi request reprint Invasive pneumococcal disease in children can reveal a primary immunodeficiency
    Jean Gaschignard
    Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale UMR1163 University Paris Descartes, Sorbonne Paris Cité, Imagine Institute, Paris, France Groupe de Pathologie Infectieuse Pédiatrique, France
    Clin Infect Dis 59:244-51. 2014
    ..Some primary immunodeficiencies (PIDs) are known to confer predisposition to IPD. However, a systematic search for these PIDs has never been carried out in children presenting with IPD...
  66. ncbi request reprint [Vaccines' adverse events: questions and answers brought by InfoVac]
    R Cohen
    Infovac France, 27, rue d Inkermann, 94100 Saint Maur des Fossés, France
    Arch Pediatr 13:650-2. 2006
  67. ncbi request reprint Paediatric varicella hospitalisations in France: a nationwide survey
    E Grimprel
    Groupe de pathologie infectieuse pédiatrique de la Société française de pédiatrie, Paris, France
    Clin Microbiol Infect 13:546-9. 2007
    ..1%). Forty-nine patients had sequelae and eight patients died. Surveillance should continue in France with a view to the future implementation of a universal vaccination programme...
  68. ncbi request reprint [Influenza rapid diagnostic tests: are they beneficial in the pediatric emergency department or in ambulatory pediatrics?]
    F de La Rocque
    ACTIV Association Clinique et Thérapeutique Infantile du Val de Marne, 27, rue d Inkermann, 94100 Saint Maur des Fossés, France
    Arch Pediatr 14:532-3. 2007
  69. ncbi request reprint [Impact of the rapid diagnosis downtown in the assumption of responsibility of the children in period of influenza]
    R Cohen
    Service de Microbiologie, Centre Hospitalier Intercommunal de Creteil, 40, avenue de Verdun, 94000 Creteil, France
    Arch Pediatr 14:926-31. 2007
    ..0003). This study confirms the difficulty of clinical diagnosis, and shows the interest of IRDT for the diagnosis of influenza and consequently to improve the management of influenza in children in ambulatory paediatric setting...
  70. ncbi request reprint [French paediatrician and general practitioner's survey about actual and future BCG use]
    F de La Rocque
    Association Clinique et Thérapeutique Infantile du Val de Marne ACTIV, 27, rue d Inkermann, 94100 Saint Maur des Fossés, France
    Arch Pediatr 12:1665-9. 2005
    ..6%). It seems not acceptable for 2/3 of physicians to address their patients to colleagues or to specialized structures...
  71. ncbi request reprint [Pediatric infections network]
    R Cohen
    ACTIV, 27, rue Inkermann, 94100 Saint Maur des Fossés, France
    Arch Pediatr 13:634-5. 2006
  72. ncbi request reprint [Vaccination in parents of young infants survey]
    F de La Rocque
    Association Clinique et Thérapeutique Infantile du Val de Marne ACTIV, 27, Saint Maur des Fossés, France
    Arch Pediatr 14:1472-6. 2007
    ..Rubella catch up strategy should be improved. Adults' vaccination strategies and guidelines need to be better broadcasted to health care professionals and also families...
  73. doi request reprint [Analysis of delayed cerebrospinal fluid sterilization of pneumococcal meningitis in children]
    L Hees
    Service de Pediatrie Generale, hôpital Valence, 179 Bd Maréchal Juin 26000 Valence, France
    Arch Pediatr 15:S119-25. 2008
    ..The aim of this study was to analyze specifically delayed cerebrospinal fluid sterilization, identified during the first 5 years of the French observatory of children bacterial meningitis...
  74. ncbi request reprint [French survey about intradermal BCG SSI adverse events in children under 6 years of age]
    M A Dommergues
    Service de Pediatrie, Hopital Andre Mignot, 177, rue de Versailles, 78157 Le Chesnay Cedex, France
    Arch Pediatr 14:102-8. 2007
    ..Our aim is to start a prospective follow-up of BCG-SSI vaccination and its AE; 58% physicians who answered this investigation agreed to participate...
  75. doi request reprint Clonal expansion of the macrolide resistant ST386 within pneumococcal serotype 6C in France
    Claire Janoir
    Centre National de Référence des Pneumocoques CNRP, AP HP Hôpital Européen Georges Pompidou, Paris, France Département de Microbiologie, Faculté de Pharmacie EA4043, Chatenay Malabry, France
    PLoS ONE 9:e90935. 2014
    ..Finally, the decrease observed in nasopharyngeal 6C carriage since 2010, likely related to the PCV13 introduction in the French immunization schedule, is expected to lead to a decrease in 6C IPD in adults thereafter. ..
  76. doi request reprint [Attributes of elaboration and dissemination strategies that influence the implementation of clinical practice guidelines]
    A Martinot
    Service de Pediatrie Generale, urgences et maladies infectieuses, Departement de Pediatrie, Hopital Jeanne de Flandre, avenue Eugene Avinee, 59037 Lille Cedex, France
    Arch Pediatr 15:656-8. 2008
  77. doi request reprint [Osteoarticular infections: clinical studies]
    E Grimprel
    Groupe de pathologie infectieuse pédiatrique de la Société française de pédiatrie, Hopital Armand Trousseau, 26 av Dr Arnold Netter 75012 Paris, Universite Pierre et Marie Curie Paris VI, France
    Arch Pediatr 15:S68-73. 2008
    ..The aim of this article is to review the evolution of therapeutic concepts of treatment of bone and joint infections in paediatrics for 40 years with the aid of main published clinical studies...
  78. pmc Resistance to macrolides in Streptococcus pyogenes in France in pediatric patients
    E Bingen
    Service de Microbiologie, Hopital Robert Debre, 75019 Paris, France
    Antimicrob Agents Chemother 44:1453-7. 2000
    ..Among the eight ribotypes, the mefA gene was recovered from six clusters, one being predominant, while the ermB gene was recovered from four clusters, of which two were predominant...
  79. doi request reprint Pharmacodynamics and pharmacokinetics of antibacterial drugs in the management of febrile neutropenia
    Olivier Lortholary
    Universite Paris Descartes, Department of Infectious and Tropical Diseases, Centre d Infectiologie Necker Pasteur, Hopital Necker Enfants Malades, Paris, France
    Lancet Infect Dis 8:612-20. 2008
    ....
  80. doi request reprint Congenital toxoplasmosis and reinfection during pregnancy: case report, strain characterization, experimental model of reinfection, and review
    Annie Elbez-Rubinstein
    Service de Neonatologie, Hopital Intercommunal de Creteil, Creteil, France
    J Infect Dis 199:280-5. 2009
    ....
  81. ncbi request reprint [Mortality due to Streptococcus pneumoniae infection in children. A 5-year retrospective study in Ile-de-France]
    P Ovetchkine
    Service de Pediatrie Generale, Centre Hospitalier Intercommunal de Creteil, 40, avenue de Verdun, 94000 Creteil, France
    Arch Pediatr 8:747s-751s. 2001
    ..The majority of them are toddlers. Only 30% of cases occurred in high-risk children. Meningitis was the main cause of death. Pneumococcal resistance to antibiotics did not appear as a risk factor of mortality...
  82. ncbi request reprint [Pneumococcal meningitis in France: age and medical risk factors in children]
    E Bingen
    Groupe de pathologie infectieuse pédiatrique GPIP de la Société française de pédiatrie SFP, Service de Microbiologie, Hopital Robert Debre, Paris, France
    Arch Pediatr 12:1187-9. 2005
    ..The vaccine administration at two, three, four months with a booster during the second year, recommended in the vaccinal french calendar, seems particularly adapted to the Sp BM in France...
  83. ncbi request reprint Treatment failure in otitis media: an analysis
    R Cohen
    Department of Microbiology, Intercommunal Hospital, , France
    J Chemother 6:17-22; discussion 23-4. 1994
    ..The multiresistance of S. pneumoniae poses a serious therapeutic problem and should make myringotomy and bacteriological sampling obligatory in cases of antibiotic treatment failure...
  84. doi request reprint [Surveillance of Haemophilus Influenzae meningitis in children in France, 2001-2006]
    D Pop-Jora
    Service de Néphrologie et Pédiatrie Générale, Hopital Armand Trousseau, Hopital Armand Trousseau, Paris, Universite Pierre et Marie Curie Paris VI, France
    Arch Pediatr 15:S148-53. 2008
    ..The aim of our study was to describe the residual Haemophilus influenzae (Hi) meningitis in the French paediatric population between 2001 and 2006...
  85. doi request reprint [Streptococcus B meningitis in infants older than 3 months]
    J Guilbert
    Réanimation néonatale et pédiatrique, Hopital Armand Trousseau, APHP, Paris 12, France
    Arch Pediatr 15:S133-7. 2008
    ..pneumoniae (PNC) meningitis, main germ responsible for bacterial meningitis in children less than 2 years old...
  86. ncbi request reprint [Streptococcus pneumoniae serotypes involved in children with pleural empyemas in France]
    H Bekri
    Service de Pediatrie, Centre Hospitalier Intercommunal, 40, allée de la source, 94190 Villeneuve Saint Georges, France
    Arch Pediatr 14:239-43. 2007
    ..Potential prevention of pleural empyemas by the heptavalent pneumococcal conjugate vaccine is dependent on adequation between specific pneumococcal serogroups present in vaccine and those responsible for empyemas...
  87. doi request reprint [Pneumococcal meningitis: impact of heptavalent pneumococcal conjugate vaccine]
    E Bingen
    Groupe de pathologie infectieuse pédiatrique de la Société française de pédiatrie, France
    Arch Pediatr 15:543-4. 2008
  88. ncbi request reprint [Actual antimicrobial chemotherapy prescription in infant and child]
    A Bourrillon
    Service de Pediatrie Generale, Hopital Robert Debre, 48, boulevard Serurier, 75935 Paris Cedex 19, France
    Arch Pediatr 14:932-42. 2007
    ....
  89. ncbi request reprint [National surveillance of bacterial meningitis in children]
    R Cohen
    Groupe de Pathologie Infectieuse Pédiatrique, Service de Pediatrie, Hopital Intercommunal de Creteil, 40, avenue de Verdun, 94010 Creteil, France
    Arch Pediatr 10:114s-115s. 2003
  90. ncbi request reprint [Pleural empyema: from pharmacokinetic/pharmacodynamic parameters forwards therapeutic options]
    R Cohen
    Service de Microbiologie, Hopital Intercommunal de Creteil, 40, avenue de Verdun, 94000, Creteil, France
    Arch Pediatr 12:835-7. 2005
  91. pmc Pertussis surveillance in private pediatric practices, France, 2002-2006
    Nicole Guiso
    Emerg Infect Dis 14:1159-61. 2008
  92. ncbi request reprint Multinational study of pneumococcal serotypes causing acute otitis media in children
    William P Hausdorff
    Wyeth Vaccines, West Henrietta, NY 14586, USA
    Pediatr Infect Dis J 21:1008-16. 2002
    ..More than 90 immunologically distinct pneumococcal serotypes have been identified, but limited information is available regarding their relative importance in AOM...
  93. ncbi request reprint Child vaccination policies in Europe: a report from the Summits of Independent European Vaccination Experts
    Heinz J Schmitt
    Paediatric Infectious Diseases, Epidemiology and Vaccine Development, Centre for Preventive Paediatrics, Johannes Gutenberg University, Mainz, Germany
    Lancet Infect Dis 3:103-8. 2003
    ..The system as well as the schedule used would then be of minor importance...
  94. ncbi request reprint A randomized trial of teaching bioethics to surgical residents
    Anja Robb
    Centre for Research in Education, University of Toronto, Toronto, Canada
    Am J Surg 189:453-7. 2005
    ..The best method for teaching bioethics to residents is unclear. We compared the effectiveness of a standardized patient (SP)-based seminar to a traditional seminar format for teaching bioethics to surgical residents...
  95. ncbi request reprint Antioxidant therapy for chronic hepatitis C after failure of interferon: results of phase II randomized, double-blind placebo controlled clinical trial
    Ezra Gabbay
    Liver Unit, Department of Medicine, Hebrew University, Hadassah Medical Center, POB 12000, Jerusalem IL 91120, Israel
    World J Gastroenterol 13:5317-23. 2007
    ..To assess the safety and efficacy of antioxidant therapy for patients with chronic hepatitis C virus (HCV) infection...
  96. ncbi request reprint Changes in the attitudes of Israeli students at the Hebrew University Medical School toward residency in psychiatry: a cohort study
    Itai Gat
    Hebrew University Medical School, Jerusalem, Israel
    Isr J Psychiatry Relat Sci 44:194-203. 2007
    ..Our aim was to examine changes in the attitudes of Israeli medical students toward different specialties, including psychiatry, over the course of their training. We attempted to identify trends and patterns in these perceptions...