Sylvie Euvrard

..Transplant recipients in whom cutaneous squamous-cell carcinomas develop are at high risk for multiple subsequent skin cancers. Whether sirolimus is useful in the prevention of secondary skin cancer has not been assessed...

..The aim of this study was to compare the individual rate of subsequent skin cancers in kidney (KTR) and heart transplant recipients (HTR) after the first squamous cell carcinoma (SCC) and to assess risk factors for tumor multiplicity...

..Discerning the role of each drug is complicated owing to the fact that most patients generally have combinations of several medications...

..Although several studies have been devoted to adult transplant patients, few data are available on the long-term skin malignancies following pediatric organ transplantation...

..Primary prevention requires that patients be educated about strict sun protection from the transplant onwards and have a routine annual dermatologic examination enabling early treatment of lesions...

..The factors enhancing Kaposi's sarcoma associated with the HHV8 virus remain to be defined. The possibility of transmission of the infection through the graft must lead to the systematic search for this virus in the donors...

..An investigation was undertaken into the effects of SRL on squamous cell carcinoma (SCC) developing in organ transplant recipients (OTR) receiving immunosuppressive treatments, with special emphasis on vascularization...

..Warts are thought to be associated with the development of squamous cell carcinoma (SCC) in organ transplant patients. We investigated the association between the different types of warts and SCC in organ transplant patients...

..To assess the clinicopathologic features of basal cell carcinomas developing in organ transplant recipients...

..We describe the first case of trichilemmal carcinoma presenting with a misleading clinical aspect in a heart transplant recipient. We then briefly outline the salient clinicopathologic features of this malignancy...

..This unique observation suggests that retransplantation of patients with previous posttransplantation KS is possible...

..We speculate that this lesion developed from pre-existing Bowen's disease extending to the hair follicles...

..Evidence of dissemination is difficult because of the poor sensitivity of diagnostic tests. Fluconazole was the treatment of choice in association with immunosuppressive treatment tapering...

..Basosquamous cell carcinoma (BSCC) is a poorly known tumor showing pathological features of both basal and squamous cell carcinomas. BSCC has never been specifically studied in organ transplant recipients (OTRs)...

..This case suggests that a rapidly growing orf in transplant patients behaves as an opportunistic infection and therefore minimization should be considered along with a topical treatment...

..No association between TP53 arginine/arginine genotype and human papillomavirus status could be determined, however...

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..The pattern of malignancies that occur in the paediatric graft population is different from that in the general paediatric population and in the population of adult organ transplant recipients...

..Topical imiquimod is a new immunomodulator agent approved for genital warts, actinic keratosis (AK) or carcinoma, occurring in immunocompetent patients...

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..In conclusion, stem cells originating from a grafted kidney may migrate to the skin, differentiate, or fuse as keratinocytes that could, rarely, undergo cancer transformation...

..There are few published studies or reviews, which provide guidance to the clinician in the treatment of these patients...

..01). Thus, quantification of KSHV load in peripheral blood mononuclear cells could represent a useful tool for monitoring transplant recipients with KS...

..Intolerance of adverse effects in this context suggests the need for novel approaches with these challenging patients...

..Preventive, early, and aggressive therapeutic interventions are required to minimize this serious complication of transplant-associated immunosuppression...

..Cytokines triggered in the course of organ transplantation include IL-10. This molecule may induce expression of HLA-G, which in turn may be implicated in tumor development in transplanted recipients...

..Merkel cell carcinoma is an uncommon neuroendocrine skin tumor, of which 67 cases have been reported up till now, usually briefly, in organ transplant patients...

..Regardless of the clinic design used, an organized and firmly established clinic model to allow proactive and ongoing care for these patients is important for education, prevention, and early intervention...

..Our intent is to provide an overview of the current knowledge regarding nontumoral dermatologic problems associated with liver transplantation by summarizing the available information from all documented case reports...