F Zerbib

Summary

Affiliation: CHU de Bordeaux
Country: France

Publications

  1. ncbi request reprint Comparison of quality of life and anorectal function after artificial sphincter implantation
    Paul Antoine Lehur
    Clinique chirurgicale II, Hotel Dieu, Nantes, France
    Dis Colon Rectum 45:508-13. 2002
  2. doi request reprint Novel therapeutics for gastro-esophageal reflux symptoms
    Frank Zerbib
    CHU Bordeaux, Saint Andre Hospital, Gastroenterology Department, Bordeaux, F 33075, France
    Expert Rev Clin Pharmacol 5:533-41. 2012
  3. doi request reprint Normal values of pharyngeal and esophageal 24-hour pH impedance in individuals on and off therapy and interobserver reproducibility
    Frank Zerbib
    CHU Bordeaux, Saint Andre Hospital, Gastroenterology and Hepatology Department, and Bordeaux Segalen University, Bordeaux, France
    Clin Gastroenterol Hepatol 11:366-72. 2013
  4. doi request reprint Functional heartburn: definition and management strategies
    Frank Zerbib
    Gastroenterology and Hepatology Department, Saint Andre Hospital, Centre Hospitalier Universitaire de Bordeaux
    Curr Gastroenterol Rep 14:181-8. 2012
  5. doi request reprint Clinical, but not oesophageal pH-impedance, profiles predict response to proton pump inhibitors in gastro-oesophageal reflux disease
    Frank Zerbib
    Gastroenterology and Hepatology Department, CHU Bordeaux, Saint Andre Hospital, Bordeaux, Bordeaux, France
    Gut 61:501-6. 2012
  6. ncbi request reprint Determinants of gastro-oesophageal reflux perception in patients with persistent symptoms despite proton pump inhibitors
    F Zerbib
    CHU Bordeaux, Saint Andre Hospital, Gastroenterology Department, Bordeaux, France
    Gut 57:156-60. 2008
  7. doi request reprint Management of laryngopharyngeal reflux: an unmet medical need
    F Zerbib
    CHU Bordeaux, Saint Andre Hospital, Gastroenterology Department, Bordeaux, France
    Neurogastroenterol Motil 22:109-12. 2010
  8. ncbi request reprint [Measurement of esophageal impedance in gastro-esophageal reflux disease: results and perspectives]
    Frank Zerbib
    Service d Hepato Gastroenterologie, Hôpital Saint André, Bordeaux
    Gastroenterol Clin Biol 27:451-4. 2003
  9. ncbi request reprint [Does H. pylori infection or its eradication play a role in gastroeosphageal reflux disease?]
    Frank Zerbib
    Service d Hepato Gastroenterologie, Hôpital Saint André, 33075 Bordeaux cedex
    Gastroenterol Clin Biol 27:427-31. 2003
  10. doi request reprint Medical treatment of GORD. Emerging therapeutic targets and concepts
    Frank Zerbib
    CHU Bordeaux, Saint Andre Hospital, Gastroenterology Department, France
    Best Pract Res Clin Gastroenterol 24:937-46. 2010

Collaborators

Detail Information

Publications37

  1. ncbi request reprint Comparison of quality of life and anorectal function after artificial sphincter implantation
    Paul Antoine Lehur
    Clinique chirurgicale II, Hotel Dieu, Nantes, France
    Dis Colon Rectum 45:508-13. 2002
    ....
  2. doi request reprint Novel therapeutics for gastro-esophageal reflux symptoms
    Frank Zerbib
    CHU Bordeaux, Saint Andre Hospital, Gastroenterology Department, Bordeaux, F 33075, France
    Expert Rev Clin Pharmacol 5:533-41. 2012
    ..Esophageal hypersensitivity and impaired mucosal integrity may prove to be relevant therapeutic targets in the future...
  3. doi request reprint Normal values of pharyngeal and esophageal 24-hour pH impedance in individuals on and off therapy and interobserver reproducibility
    Frank Zerbib
    CHU Bordeaux, Saint Andre Hospital, Gastroenterology and Hepatology Department, and Bordeaux Segalen University, Bordeaux, France
    Clin Gastroenterol Hepatol 11:366-72. 2013
    ..We performed a multicenter study to establish normal values of pharyngeal and esophageal pH-impedance monitoring in individuals on and off therapy and to determine the interobserver reproducibility of this technique...
  4. doi request reprint Functional heartburn: definition and management strategies
    Frank Zerbib
    Gastroenterology and Hepatology Department, Saint Andre Hospital, Centre Hospitalier Universitaire de Bordeaux
    Curr Gastroenterol Rep 14:181-8. 2012
    ..The use of pain modulators is recommended by most experts despite the lack of appropriate clinical trials to support it...
  5. doi request reprint Clinical, but not oesophageal pH-impedance, profiles predict response to proton pump inhibitors in gastro-oesophageal reflux disease
    Frank Zerbib
    Gastroenterology and Hepatology Department, CHU Bordeaux, Saint Andre Hospital, Bordeaux, Bordeaux, France
    Gut 61:501-6. 2012
    ..The aim of this study was to determine whether any symptom profile or reflux pattern was associated with refractoriness to PPI therapy...
  6. ncbi request reprint Determinants of gastro-oesophageal reflux perception in patients with persistent symptoms despite proton pump inhibitors
    F Zerbib
    CHU Bordeaux, Saint Andre Hospital, Gastroenterology Department, Bordeaux, France
    Gut 57:156-60. 2008
    ..Approximately 20% of patients have persistent symptoms of gastro-oesophageal reflux despite proton pump inhibitor (PPI) therapy. The aim of this study was to assess the determinants of reflux perception in patients on PPI therapy...
  7. doi request reprint Management of laryngopharyngeal reflux: an unmet medical need
    F Zerbib
    CHU Bordeaux, Saint Andre Hospital, Gastroenterology Department, Bordeaux, France
    Neurogastroenterol Motil 22:109-12. 2010
    ..Therefore, there is a need for the development of new tools which may help to better identify the subgroup of patients with laryngeal symptoms related to supra-esophageal reflux...
  8. ncbi request reprint [Measurement of esophageal impedance in gastro-esophageal reflux disease: results and perspectives]
    Frank Zerbib
    Service d Hepato Gastroenterologie, Hôpital Saint André, Bordeaux
    Gastroenterol Clin Biol 27:451-4. 2003
  9. ncbi request reprint [Does H. pylori infection or its eradication play a role in gastroeosphageal reflux disease?]
    Frank Zerbib
    Service d Hepato Gastroenterologie, Hôpital Saint André, 33075 Bordeaux cedex
    Gastroenterol Clin Biol 27:427-31. 2003
    ..However, conflicting results have been reported, so that further studies are needed before considering eradication of H. pylori systematically before long-term medical treatment for GERD...
  10. doi request reprint Medical treatment of GORD. Emerging therapeutic targets and concepts
    Frank Zerbib
    CHU Bordeaux, Saint Andre Hospital, Gastroenterology Department, France
    Best Pract Res Clin Gastroenterol 24:937-46. 2010
    ..These drugs will probably be developed as add-on therapy in combination with PPIs provided the tolerability and safety issues are resolved...
  11. ncbi request reprint Effects of bronchial obstruction on lower esophageal sphincter motility and gastroesophageal reflux in patients with asthma
    Frank Zerbib
    Service d Hepato Gastroenterologie, Hôpital Saint André, Bordeaux
    Am J Respir Crit Care Med 166:1206-11. 2002
    ..These results support the belief that, in asthma, bronchial obstruction may be responsible for reflux or may aggravate reflux through a mechanism that remains to be further clarified...
  12. ncbi request reprint [Treatment of NSAIDs related dyspepsia]
    Frank Zerbib
    Service d Hepato Gastroenterologie, Hôpital Saint André, Bordeaux
    Gastroenterol Clin Biol 28:C73-6. 2004
    ..Proton pump inhibitors appear to be the treatment of choice for NSAIDs-induced dyspepsia...
  13. ncbi request reprint Normal values and day-to-day variability of 24-h ambulatory oesophageal impedance-pH monitoring in a Belgian-French cohort of healthy subjects
    F Zerbib
    Gastroenterology Department, Saint Andre Hospital, Bordeaux, France
    Aliment Pharmacol Ther 22:1011-21. 2005
    ..Impedance-pH monitoring is the most sensitive method for detection and characterization of gastro-oesophageal reflux episodes. Normal values from European subjects are lacking...
  14. doi request reprint Study of Helicobacter pullorum proinflammatory properties on human epithelial cells in vitro
    C Varon
    INSERM U853, Bordeaux, France
    Gut 58:629-35. 2009
    ..The aim of the present study was to determine whether H pullorum exerts a direct effect on human intestinal epithelial cells in vitro and to characterise the bacterial mechanisms and the signalling pathways involved...
  15. doi request reprint Randomised clinical trial: effects of monotherapy with ADX10059, a mGluR5 inhibitor, on symptoms and reflux events in patients with gastro-oesophageal reflux disease
    F Zerbib
    Gastroenterology Department, CHU Bordeaux, Saint Andre Hospital, and Université Victor Segalen Bordeaux 2, Bordeaux, France
    Aliment Pharmacol Ther 33:911-21. 2011
    ....
  16. ncbi request reprint Long-term effects of Helicobacter pylori eradication on gastric antral mucosa in duodenal ulcer patients
    F Zerbib
    Department of Gastroenterology, Saint Andre Hospital, Bordeaux, France
    Eur J Gastroenterol Hepatol 12:719-25. 2000
    ..The aim of this study was to assess the consequences of prolonged Helicobacter pylori eradication on gastric antral mucosa in duodenal ulcer patients...
  17. doi request reprint Prediction of Crohn's disease relapse with faecal calprotectin in infliximab responders: a prospective study
    D Laharie
    CHU Bordeaux, Gastroenterology Department, Haut Leveque Hospital, Pessac, France
    Aliment Pharmacol Ther 34:462-9. 2011
    ..Faecal calprotectin is a reliable tool for predicting Crohn's disease (CD) relapse in patients with sustained remission. Prediction of relapse with faecal calprotectin has been less studied in patients with severe CD treated with anti-TNF...
  18. doi request reprint Efficacy, tolerability and pharmacokinetics of a modified release formulation of ADX10059, a negative allosteric modulator of metabotropic glutamate receptor 5: an esophageal pH-impedance study in healthy subjects
    F Zerbib
    Gastroenterology Department, Saint Andre Hospital, CHU Bordeaux, Bordeaux, France
    Neurogastroenterol Motil 22:859-65, e231. 2010
    ..This study evaluated ADX10059 modified-release (MR) formulation pharmacokinetics, tolerability, and pharmacodynamics...
  19. ncbi request reprint Peptic ulcer disease in a patient with ankylosing spondylitis receiving a conventional nonsteroidal anti-inflammatory drug
    Bernard Bannwarth
    Teaching Hospital Pellegrin, Bordeaux, France
    Nat Clin Pract Rheumatol 2:107-11;quiz 112. 2006
    ..pylori: omeprazole 20 mg twice daily, clarithromycin 500 mg twice daily and amoxicillin 1 g twice daily for 1 week. For ankylosing spondylitis: diclofenac 150 mg/day in combination with omeprazole 20 mg/day for 2 months...
  20. ncbi request reprint Validation of the French version of the Fecal Incontinence Quality-of-Life (FIQL) scale
    Eric Rullier
    Fédération Médico Chirurgicale d Hépato Gastroentérologie, Hôpital Saint André, Bordeaux
    Gastroenterol Clin Biol 28:562-8. 2004
    ..The aim of this multicenter study was to validate the French version of the fecal incontinence quality-of-life scale (FIQL scale) developed in the Unites States of America...
  21. ncbi request reprint Predictors of response to infliximab in luminal Crohn's disease
    David Laharie
    Service d Hepato Gastroenterologie, Hopital Haut Leveque, 33600 Pessac
    Gastroenterol Clin Biol 29:145-9. 2005
    ..To identify predictive factors of response to infliximab in luminal Crohn's disease (CD)...
  22. pmc Sphincter-saving resection for all rectal carcinomas: the end of the 2-cm distal rule
    Eric Rullier
    Department of Surgery, Saint Andre Hospital, Bordeaux, France
    Ann Surg 241:465-9. 2005
    ..To assess oncologic outcome of patients treated by conservative radical surgery for tumors below 5 cm from the anal verge...
  23. pmc Identification of a genetic marker of Helicobacter pylori strains involved in gastric extranodal marginal zone B cell lymphoma of the MALT-type
    P Lehours
    Laboratoire de Bacteriologie, Universite Victor Segalen Bordeaux 2, Bordeaux, France
    Gut 53:931-7. 2004
    ..Currently, no bacterial factor has been associated with the development of this disease. Our aim was to identify genes associated with lymphoma development...
  24. ncbi request reprint Long-term functional results after sphincter-saving resection for rectal cancer
    Frederic Bretagnol
    Service de Chirurgie Digestive, Hôpital Saint André, 33075 Bordeaux, France
    Gastroenterol Clin Biol 28:155-9. 2004
    ..The aim of this study was to assess frequency and risk factors of long-term gastrointestinal side effects after sphincter-saving resection for rectal cancer...
  25. ncbi request reprint Esophageal pH-impedance monitoring and symptom analysis in GERD: a study in patients off and on therapy
    Frank Zerbib
    Gastroenterology Department, Saint Andre Hospital, Bordeaux, France
    Am J Gastroenterol 101:1956-63. 2006
    ..However, the role of nonacid reflux in the pathogenesis of symptoms is poorly known. The aim of this study was to evaluate the diagnostic yield of this technique in patients with suspected reflux symptoms while on or off PPI therapy...
  26. ncbi request reprint Comparison of functional results and quality of life between intersphincteric resection and conventional coloanal anastomosis for low rectal cancer
    Frederic Bretagnol
    Department of Digestive Surgery, Saint Andre Hospital, Bordeaux, France
    Dis Colon Rectum 47:832-8. 2004
    ..This study aimed to investigate functional results and quality of life after intersphincteric resection compared with conventional coloanal anastomoses...
  27. pmc Relationship between rectal sensitivity, symptoms intensity and quality of life in patients with irritable bowel syndrome
    J M Sabate
    AP HP, Hopital Louis Mourier, Service d Hepato Gastroenterologie, Colombes, and INSERM, U 792, APHP, CHU Ambroise Pare, Montpellier, France
    Aliment Pharmacol Ther 28:484-90. 2008
    ..Relationships between pain threshold during rectal distension and both symptoms intensity and alteration in quality of life (QoL) in irritable bowel syndrome (IBS) patients have been poorly evaluated...
  28. pmc Preoperative radiochemotherapy and sphincter-saving resection for T3 carcinomas of the lower third of the rectum
    E Rullier
    Department of Surgery, Saint Andre Hospital, Bordeaux, France
    Ann Surg 234:633-40. 2001
    ..To evaluate the complications and oncologic and functional results of preoperative radiochemotherapy and sphincter-saving resection for T3 cancers of the lower third of the rectum...
  29. doi request reprint Association between entero-hepatic Helicobacter species and Crohn's disease: a prospective cross-sectional study
    D Laharie
    INSERM, U853, Bordeaux, Univ Bordeaux 2, Bordeaux, France
    Aliment Pharmacol Ther 30:283-93. 2009
    ..Aim To look for an association between CD and the presence of EHH DNA in intestinal biopsies...
  30. ncbi request reprint Colonic metastasis of a renal carcinoma. A case report
    F Zerbib
    Department of Gastro-enterology, , Bordeaux, France
    Tumori 78:219-20. 1992
    ..The endoscopy revealed a polypoid mass in the left colon which proved to be a metastasis of the renal carcinoma. This is an uncommon cause of intestinal hemorrhage, and a rare localization of metastatic deposits...
  31. ncbi request reprint Effect of rebamipide on the colonic barrier in interleukin-10-deficient mice
    David Laharie
    INSERM ERI 10, Universite Victor Segalen, Bordeaux, France
    Dig Dis Sci 52:84-92. 2007
    ..These properties could be helpful in the management of some inflammatory bowel diseases...
  32. pmc Evaluation of the association of nine Helicobacter pylori virulence factors with strains involved in low-grade gastric mucosa-associated lymphoid tissue lymphoma
    Philippe Lehours
    Laboratoire de Bacteriologie, Universite Victor Segalen Bordeaux 2, Bordeaux, France
    Infect Immun 72:880-8. 2004
    ..Our data confirmed that H. pylori virulence factors are correlated with one another. If the involvement of H. pylori in MALT lymphoma is well established, the pathomechanism by which gastric lymphoma occurs remains to be identified...
  33. ncbi request reprint [Treatment of Crohn's disease with anti-TNF alpha antibodies (infliximab): results of a multicentric and retrospective study]
    Marie Doubremelle
    Hépato Gastroentérologie, Hotel Dieu, Nantes
    Gastroenterol Clin Biol 26:973-9. 2002
    ..To evaluate the results of infliximab therapy, an anti-TNF-alpha antibody, in patients with severe and refractory Crohn's disease or with fistulas, treated outside the setting of a therapeutic trial...
  34. ncbi request reprint ReQuest: a new questionnaire for the simultaneous evaluation of symptoms and well-being in patients with gastro-oesophageal reflux
    Philippe Ducrotte
    Département d Hépato Gastroentérologie et de Nutrition, Hopital Charles Nicolle, Rouen, France
    Digestion 75:79-86. 2007
    ..Both versions, the long and the short, have identical metrological qualities...
  35. ncbi request reprint Bifidobacterium breve and Streptococcus thermophilus secretion products enhance T helper 1 immune response and intestinal barrier in mice
    Sandrine Menard
    INSERM EMI 0212, Faculté Cochin Necker, 156 rue de Vaugirard, 75730 Paris, France
    Exp Biol Med (Maywood) 230:749-56. 2005
    ....
  36. ncbi request reprint Two-dimensional blue native/SDS gel electrophoresis of multiprotein complexes from Helicobacter pylori
    Slovénie Pyndiah
    INSERM, U853, Bordeaux, F 33076 France
    Mol Cell Proteomics 6:193-206. 2007
    ....
  37. ncbi request reprint Evaluation of the homologous recombination in Helicobacter pylori
    Slovénie Pyndiah
    INSERM ESPRI 2004, Laboratoire de Bacteriologie, UniversitéVictor Segalen Bordeaux 2, 33076 Bordeaux Cedex, France
    Helicobacter 10:185-92. 2005
    ..Most strategies for direct mutagenesis of Helicobacter pylori primarily involve genomic DNA cloning which is a time-consuming and expensive technique...