M Wager

Summary

Affiliation: CHU de Poitiers
Country: France

Publications

  1. doi request reprint [Molecular biology of adult gliomas: some landmarks for neurosurgeons]
    M Wager
    Service de Neurochirurgie, tour Jean Bernard, CHU de Poitiers, 2, rue de la Miletrie, B P 577, 86021 Poitiers Cedex, France
    Neurochirurgie 54:529-44. 2008
  2. doi request reprint Intraoperative monitoring of an aspect of executive functions: administration of the Stroop test in 9 adult patients during awake surgery for resection of frontal glioma
    Michel Wager
    Department of Neurosurgery, Imaging Laboratory, University Hospital Poitiers, 2 rue de la Miletrie, Poitiers Cedex, France
    Neurosurgery 72:ons169-80; discussion ons180-1. 2013
  3. pmc An ANOCEF genomic and transcriptomic microarray study of the response to radiotherapy or to alkylating first-line chemotherapy in glioblastoma patients
    François Ducray
    INSERM, U842, Lyon, F 69372 France
    Mol Cancer 9:234. 2010
  4. pmc Prognostic molecular markers with no impact on decision-making: the paradox of gliomas based on a prospective study
    M Wager
    Neurosurgery Department, University Hospital, Poitiers, France
    Br J Cancer 98:1830-8. 2008
  5. pmc Prognostic value of increase in transcript levels of Tp73 DeltaEx2-3 isoforms in low-grade glioma patients
    M Wager
    Neurosurgery Department, University Hospital, Poitiers, France
    Br J Cancer 95:1062-9. 2006
  6. ncbi request reprint Cauda equina tumors: a French multicenter retrospective review of 231 adult cases and review of the literature
    M Wager
    Service de Neurochirurgie, C H U, La Miletrie, Poitiers, France
    Neurosurg Rev 23:119-29; discussion 130-1. 2000
  7. ncbi request reprint Correlation of clinical features and methylation status of MGMT gene promoter in glioblastomas
    J L Blanc
    Laboratory of Molecular Oncology, EA 2224, IBMIG, Poitiers, France
    J Neurooncol 68:275-83. 2004
  8. doi request reprint [Structural and molecular organization, development and maturation of the neuromuscular junction]
    P Rigoard
    Service de Neurochirurgie, CHU La Miletrie, 2, rue de la Miletrie, BP 577, 86021 Poitiers Cedex, France
    Neurochirurgie 55:S34-42. 2009
  9. doi request reprint [Anatomy and physiology of the peripheral nerve]
    P Rigoard
    Service de Neurochirurgie, CHU La Miletrie, 2, rue de la Miletrie, BP 577, 86021 Poitiers Cedex, France
    Neurochirurgie 55:S3-12. 2009
  10. doi request reprint [Major mechanisms involved in the synaptic transmission of the neuromuscular apparatus]
    S Rigoard
    Service des Urgences, CHU La Miletrie, 2, rue de La Miléterie, BP 577, 86021 Poitiers, France
    Neurochirurgie 55:S22-33. 2009

Collaborators

Detail Information

Publications21

  1. doi request reprint [Molecular biology of adult gliomas: some landmarks for neurosurgeons]
    M Wager
    Service de Neurochirurgie, tour Jean Bernard, CHU de Poitiers, 2, rue de la Miletrie, B P 577, 86021 Poitiers Cedex, France
    Neurochirurgie 54:529-44. 2008
    ..Consequently, the clinician must assimilate a large amount of information, raising the question of the genuine role of these biomarkers in the daily care of these patients...
  2. doi request reprint Intraoperative monitoring of an aspect of executive functions: administration of the Stroop test in 9 adult patients during awake surgery for resection of frontal glioma
    Michel Wager
    Department of Neurosurgery, Imaging Laboratory, University Hospital Poitiers, 2 rue de la Miletrie, Poitiers Cedex, France
    Neurosurgery 72:ons169-80; discussion ons180-1. 2013
    ..Awake brain surgery allows extensive intraoperative monitoring of not only motor and sensory functions and language but also executive functions...
  3. pmc An ANOCEF genomic and transcriptomic microarray study of the response to radiotherapy or to alkylating first-line chemotherapy in glioblastoma patients
    François Ducray
    INSERM, U842, Lyon, F 69372 France
    Mol Cancer 9:234. 2010
    ..The gene expression (n = 56) and genomic profiles (n = 67) of responders and non-responders to first-line chemotherapy or radiation therapy alone were compared on Affymetrix Plus 2 gene expression arrays and BAC CGH arrays...
  4. pmc Prognostic molecular markers with no impact on decision-making: the paradox of gliomas based on a prospective study
    M Wager
    Neurosurgery Department, University Hospital, Poitiers, France
    Br J Cancer 98:1830-8. 2008
    ..This study confirms the prognostic value of several markers. However, the scattering of the values explained by tumour heterogeneity prevents their use in individual decision-making...
  5. pmc Prognostic value of increase in transcript levels of Tp73 DeltaEx2-3 isoforms in low-grade glioma patients
    M Wager
    Neurosurgery Department, University Hospital, Poitiers, France
    Br J Cancer 95:1062-9. 2006
    ..Our data are the first such molecular biology report regarding low-grade tumours and as such should be of help for sound decision-making...
  6. ncbi request reprint Cauda equina tumors: a French multicenter retrospective review of 231 adult cases and review of the literature
    M Wager
    Service de Neurochirurgie, C H U, La Miletrie, Poitiers, France
    Neurosurg Rev 23:119-29; discussion 130-1. 2000
    ..This type of tumor requires very long follow-up. Prognosis is good for hemangioblastomas. Sphincter dysfunctions carries a poor prognosis and may appear after primary surgery, more often after treatment of recurrences...
  7. ncbi request reprint Correlation of clinical features and methylation status of MGMT gene promoter in glioblastomas
    J L Blanc
    Laboratory of Molecular Oncology, EA 2224, IBMIG, Poitiers, France
    J Neurooncol 68:275-83. 2004
    ..Our observations do not lead us to consider promoter methylation of MGMT gene as a prognostic factor of responsiveness to alkylating agents in glioblastomas...
  8. doi request reprint [Structural and molecular organization, development and maturation of the neuromuscular junction]
    P Rigoard
    Service de Neurochirurgie, CHU La Miletrie, 2, rue de la Miletrie, BP 577, 86021 Poitiers Cedex, France
    Neurochirurgie 55:S34-42. 2009
    ..Neuregulin is essentially involved in Schwann cell survival and guidance for axonal growth...
  9. doi request reprint [Anatomy and physiology of the peripheral nerve]
    P Rigoard
    Service de Neurochirurgie, CHU La Miletrie, 2, rue de la Miletrie, BP 577, 86021 Poitiers Cedex, France
    Neurochirurgie 55:S3-12. 2009
    ..Recent advances in cellular and molecular biology have provided a better understanding of nerve physiology, which are reviewed here as an indispensable basis to the study of its pathology...
  10. doi request reprint [Major mechanisms involved in the synaptic transmission of the neuromuscular apparatus]
    S Rigoard
    Service des Urgences, CHU La Miletrie, 2, rue de La Miléterie, BP 577, 86021 Poitiers, France
    Neurochirurgie 55:S22-33. 2009
    ....
  11. doi request reprint [Synapse formation and regeneration]
    S d'Houtaud
    Service de Neurochirurgie, CHU La Miletrie, 2, rue de la Miletrie, BP 577, 86021 Poitiers Cedex, France
    Neurochirurgie 55:S49-62. 2009
    ..The limited ability of the CNS to create new synapses after nervous system injury will be then discussed with a final consideration of some new strategies elaborated to circumvent the limitations of lesion extension processes...
  12. doi request reprint [Molecular architecture of the sarcoplasmic reticulum and its role in the ECC]
    P Rigoard
    Service de Neurochirurgie, CHU La Miletrie, 2, rue de la Miletrie, BP 577, 86021 Poitiers Cedex, France
    Neurochirurgie 55:S83-91. 2009
    ..Ryanodine receptors (RyR) and dihydropyridine receptors (DHPR) mainly act in calcium exchanges in the SR. This particular structural and molecular architecture must be correlated to its functional specificity...
  13. ncbi request reprint [Gene MGMT and oligodendrogliomas. Fundamental data and short review of the literature]
    J L Blanc
    Service de Neurochirurgie, CHU, Poitiers
    Neurochirurgie 51:269-72. 2005
    ..This is probably due to both tumour heterogeneity and multiple parameters associated with chemosensitivity. To date, it thus appears difficult to choose the adjuvant treatment according to the sole status of MGMT...
  14. doi request reprint [Physiology of the injured peripheral nerve]
    A Delmotte
    Service de Neurochirurgie, CHU La Miletrie, 2, rue de la Miletrie, BP 577, 86021 Poitiers Cedex, France
    Neurochirurgie 55:S13-21. 2009
    ..Today's progress remains insufficient to improve functional prognosis significantly, but a better understanding of peripheral nerve regenerating processes has opened the door to new medical and surgical advances...
  15. doi request reprint [Mechanisms controlling axonal sprouting at the neuromuscular junction]
    S d'Houtaud
    Service de Neurochirurgie, CHU La Miletrie, 2, rue de la Miletrie, BP 577, 86021 Poitiers Cedex, France
    Neurochirurgie 55:S63-8. 2009
    ..The lack of neuromuscular activity is also harmful in axonal sprouting, probably by impeding calcium influx into the nerve...
  16. pmc Semaphorin, neuropilin and VEGF expression in glial tumours: SEMA3G, a prognostic marker?
    L Karayan-Tapon
    Universite de Poitiers, EA 3805, CHU de Poitiers, 2 rue de la Miletrie, BP 577, Poitiers F 86021, France
    Br J Cancer 99:1153-60. 2008
    ..Moreover, in multivariate analysis, SEMA3G was found to be the only significant prognostic marker...
  17. ncbi request reprint Primary intracerebral malignant lymphoma: report of 248 cases
    B Bataille
    Department of Neurological Surgery, Radiation Oncology, Radiology, and Pathology, University of Poitiers Medical School, France
    J Neurosurg 92:261-6. 2000
    ..The authors present a retrospective analysis of 248 immunocompetent patients with primary intracerebral lymphoma treated at 19 French and Belgian medical centers between January 1980 and December 1995...
  18. ncbi request reprint [Glutamate in traumatic brain injuries]
    M Wager
    Service de Neurochirurgie, CHU La Miletrie, 350, avenue Jacques Coeur, 86021 Poitiers Cedex
    Neurochirurgie 49:97-106. 2003
    ..We discuss the role of glutamate neurotransmitters, review glutamate metabolism and actions, and then review in the pertinent literature devoted to the role of glutamate in the onset of brain injuries secondary to head trauma...
  19. ncbi request reprint [Difficulty in treating spinal chordoma of the thoracic vertebrae]
    J Soyer
    Service de Chirurgie Orthopedique, Hopital Jean Bernard, Poitiers
    Neurochirurgie 47:69-71. 2001
    ..On the basis of a review of the literature, we advocate an aggressive surgical resection from the beginning, similar to management of solitary vertebral metastasis...
  20. doi request reprint [Peripheral nerve tumors]
    F Lapierre
    Service de Neurochirurgie, CHU La Miletrie, 2, rue de la Miletrie, BP 577, 86021 Poitiers Cedex, France
    Neurochirurgie 55:413-20. 2009
    ..Surgical treatment must be clearly discussed, which, in case of schwannomas gives very good functional results. Primitive malignant tumors remain an unsolved therapeutic problem...
  21. doi request reprint [The anatomical substrate of muscle contractility]
    P Rigoard
    Service de Neurochirurgie, CHU La Miletrie, 2, rue de la Miletrie, BP 577, 86021 Poitiers Cedex, France
    Neurochirurgie 55:S69-82. 2009
    ..This paper explores muscle anatomy from its main embryologic stages of development to its histochemical specificity, including its molecular constitution, and details the main morphofunctional relations supporting muscle contraction...