Faraj Terro

Summary

Affiliation: CHU Dupuytren
Country: France

Publications

  1. ncbi request reprint BAD and Bcl-2 regulation are early events linking neuronal endoplasmic reticulum stress to mitochondria-mediated apoptosis
    Wassim Elyaman
    Department of Anatomy, Faculty of Medicine, The University of Hong Kong, Hong Kong, SAR, Hong Kong
    Brain Res Mol Brain Res 109:233-8. 2002
  2. ncbi request reprint Impairment of autophagy in the central nervous system during lipopolysaccharide-induced inflammatory stress in mice
    Arnaud Francois
    EA3808 Molecular Targets and Therapeutic of Alzheimer s Disease, University of Poitiers, Poitiers F 86073, France
    Mol Brain 7:56. 2014
  3. ncbi request reprint Longitudinal follow-up of autophagy and inflammation in brain of APPswePS1dE9 transgenic mice
    Arnaud Francois
    EA3808 Molecular Targets and Therapeutic of Alzheimer s Disease, University of Poitiers, 1 rue Georges Bonnet, 86073 Poitiers, TSA 51106, Cedex 9, France
    J Neuroinflammation 11:139. 2014
  4. pmc Involvement of interleukin-1β in the autophagic process of microglia: relevance to Alzheimer's disease
    Arnaud Francois
    EA3808 Molecular Targets and Therapeutic of Alzheimer s Disease, University of Poitiers, Poitiers F 86022, France
    J Neuroinflammation 10:151. 2013
  5. ncbi request reprint GSM-900MHz at low dose temperature-dependently downregulates α-synuclein in cultured cerebral cells independently of chaperone-mediated-autophagy
    Faraj Terro
    Groupe de Neurobiologie Cellulaire EA3842 Homéostasie cellulaire et pathologies, Faculte de Medecine, 2 Rue du Dr Raymond Marcland, 87025 Limoges Cedex, France
    Toxicology 292:136-44. 2012
  6. pmc Prevention of the β-amyloid peptide-induced inflammatory process by inhibition of double-stranded RNA-dependent protein kinase in primary murine mixed co-cultures
    J Couturier
    Research Group on Brain Aging, GReViC EA 3808, 6 rue de la Milétrie BP 199, 86034 Poitiers Cedex, France
    J Neuroinflammation 8:72. 2011
  7. ncbi request reprint Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress
    Faraj Terro
    Department of Histology and Cell Biology, Faculty of Medicine, Limoges, France
    J Neurosci Res 69:530-9. 2002
  8. ncbi request reprint The new indirubin derivative inhibitors of glycogen synthase kinase-3, 6-BIDECO and 6-BIMYEO, prevent tau phosphorylation and apoptosis induced by the inhibition of protein phosphatase-2A by okadaic acid in cultured neurons
    Ludovic Martin
    Groupe de Neurobiologie Cellulaire, EA3842 Homéostasie Cellulaire et Pathologies, Faculte de Medecine, Limoges, France
    J Neurosci Res 89:1802-11. 2011
  9. ncbi request reprint Tau protein kinases: involvement in Alzheimer's disease
    Ludovic Martin
    Groupe de Neurobiologie Cellulaire Homéostasie cellulaire et pathologies, Faculte de Medecine, Limoges, France
    Ageing Res Rev 12:289-309. 2013
  10. ncbi request reprint Tau protein phosphatases in Alzheimer's disease: the leading role of PP2A
    Ludovic Martin
    Groupe de Neurobiologie Cellulaire, Homéostasie Cellulaire et Pathologies, Faculte de Medecine, Limoges, France
    Ageing Res Rev 12:39-49. 2013

Collaborators

  • Ludovic Martin
  • Guylène Page
  • Jacques Hugon
  • Raymond Chuen Chung Chang
  • Cornelia M Wilson
  • Patrice Codogno
  • B Liagre
  • Arnaud Francois
  • Sylvie Bourthoumieu
  • Catherine Yardin
  • Marc Paccalin
  • Thierry Janet
  • Agnès Rioux Bilan
  • Amandine Magnaudeix
  • Francoise Esclaire
  • Beatrice Fernandez
  • Nathalie Quellard
  • Damien Chassaing
  • Philippe Leveque
  • J Couturier
  • Francois Labrousse
  • Armelle Rametti
  • Cecile Corbiere
  • Brigitte Gilbert
  • Isabelle Pommepuy
  • Wassim Elyaman
  • Manuela Corre-Delage
  • Alice Collin
  • Chantal Bauvy
  • R Pontcharraud
  • M Paccalin
  • B Fauconneau
  • S Milin
  • M Morel
  • Robert Saura
  • Marie Claire Vincent
  • Cécile Laroche
  • Jean Luc Eyraud
  • Jean Louis Beneytout
  • Veronique Fermeaux
  • Muriel Cantaloube
  • Michel Servaud
  • Maryse Fiorenza
  • Marie Claire Baclet
  • Antoine Bedu
  • Brigitte Dufetelle
  • Barbara Petit
  • Sandrine Robert
  • Virginie Bellet
  • Frank Trimoreau
  • Dominique Barthe
  • Ka Chun Suen

Detail Information

Publications22

  1. ncbi request reprint BAD and Bcl-2 regulation are early events linking neuronal endoplasmic reticulum stress to mitochondria-mediated apoptosis
    Wassim Elyaman
    Department of Anatomy, Faculty of Medicine, The University of Hong Kong, Hong Kong, SAR, Hong Kong
    Brain Res Mol Brain Res 109:233-8. 2002
    ..Altogether, our results indicate that neuronal ER stress is associated with an apoptotic cascade involving the mitochondria...
  2. ncbi request reprint Impairment of autophagy in the central nervous system during lipopolysaccharide-induced inflammatory stress in mice
    Arnaud Francois
    EA3808 Molecular Targets and Therapeutic of Alzheimer s Disease, University of Poitiers, Poitiers F 86073, France
    Mol Brain 7:56. 2014
    ..Therefore, this study monitored autophagy markers after acute and chronic lipopolysaccharide (LPS)-induced inflammatory stress in mice...
  3. ncbi request reprint Longitudinal follow-up of autophagy and inflammation in brain of APPswePS1dE9 transgenic mice
    Arnaud Francois
    EA3808 Molecular Targets and Therapeutic of Alzheimer s Disease, University of Poitiers, 1 rue Georges Bonnet, 86073 Poitiers, TSA 51106, Cedex 9, France
    J Neuroinflammation 11:139. 2014
    ..Therefore, a longitudinal study was performed in APPswePS1dE9 transgenic mice at three, six and twelve months of age...
  4. pmc Involvement of interleukin-1β in the autophagic process of microglia: relevance to Alzheimer's disease
    Arnaud Francois
    EA3808 Molecular Targets and Therapeutic of Alzheimer s Disease, University of Poitiers, Poitiers F 86022, France
    J Neuroinflammation 10:151. 2013
    ..However, the links between autophagy and inflammation in AD remain to be determined...
  5. ncbi request reprint GSM-900MHz at low dose temperature-dependently downregulates α-synuclein in cultured cerebral cells independently of chaperone-mediated-autophagy
    Faraj Terro
    Groupe de Neurobiologie Cellulaire EA3842 Homéostasie cellulaire et pathologies, Faculte de Medecine, 2 Rue du Dr Raymond Marcland, 87025 Limoges Cedex, France
    Toxicology 292:136-44. 2012
    ..We did not observe any immediate effect on cell viability. However, the delayed and long term consequences (protective or deleterious) of these changes on cell fate should be examined...
  6. pmc Prevention of the β-amyloid peptide-induced inflammatory process by inhibition of double-stranded RNA-dependent protein kinase in primary murine mixed co-cultures
    J Couturier
    Research Group on Brain Aging, GReViC EA 3808, 6 rue de la Milétrie BP 199, 86034 Poitiers Cedex, France
    J Neuroinflammation 8:72. 2011
    ..This led us to study the effect of a specific inhibitor of PKR on the Aβ42-induced inflammatory response in primary mixed murine co-cultures, allowing interactions between neurons, astrocytes and microglia...
  7. ncbi request reprint Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress
    Faraj Terro
    Department of Histology and Cell Biology, Faculty of Medicine, Limoges, France
    J Neurosci Res 69:530-9. 2002
    ..These data indicate that PS1 interferes with a specific apoptotic pathway that results from a dysfunction of the ER-Golgi compartment...
  8. ncbi request reprint The new indirubin derivative inhibitors of glycogen synthase kinase-3, 6-BIDECO and 6-BIMYEO, prevent tau phosphorylation and apoptosis induced by the inhibition of protein phosphatase-2A by okadaic acid in cultured neurons
    Ludovic Martin
    Groupe de Neurobiologie Cellulaire, EA3842 Homéostasie Cellulaire et Pathologies, Faculte de Medecine, Limoges, France
    J Neurosci Res 89:1802-11. 2011
    ..The neuroprotection by these compounds should be further validated in animal models of AD...
  9. ncbi request reprint Tau protein kinases: involvement in Alzheimer's disease
    Ludovic Martin
    Groupe de Neurobiologie Cellulaire Homéostasie cellulaire et pathologies, Faculte de Medecine, Limoges, France
    Ageing Res Rev 12:289-309. 2013
    ..We also reviewed the most common inhibitory compounds acting on each tau kinase...
  10. ncbi request reprint Tau protein phosphatases in Alzheimer's disease: the leading role of PP2A
    Ludovic Martin
    Groupe de Neurobiologie Cellulaire, Homéostasie Cellulaire et Pathologies, Faculte de Medecine, Limoges, France
    Ageing Res Rev 12:39-49. 2013
    ..We also reviewed the most common compounds acting on each tau phosphatase including PP2A...
  11. ncbi request reprint Linking alterations in tau phosphorylation and cleavage during neuronal apoptosis
    Armelle Rametti
    EA 3842, Homéostasie Cellulaire et Pathologie, Department of Histology and Cell Biology, Faculty of Medicine, Limoges 87025, France
    J Biol Chem 279:54518-28. 2004
    ..This mechanism may contribute to the aggregation of hyperphosphorylated tau into paired helical filaments in Alzheimer's disease where reduced PP2A activity has been reported...
  12. ncbi request reprint Monozygotic twins concordant for blood karyotype, but phenotypically discordant: a case of "mosaic chimerism"
    Sylvie Bourthoumieu
    Department of Histology, Limoges University Hospital, Limoges, France
    Am J Med Genet A 135:190-4. 2005
    ..This case and those previously reported lead us to suggest that blood is particularly unsuitable for cytogenetic investigations of twins...
  13. ncbi request reprint PP2A blockade inhibits autophagy and causes intraneuronal accumulation of ubiquitinated proteins
    Amandine Magnaudeix
    Laboratoire d Histologie, de Biologie Cellulaire et de Cytogénétique, Faculte de Medecine, Universite de Limoges, Limoges, France
    Neurobiol Aging 34:770-90. 2013
    ....
  14. pmc DC2 and keratinocyte-associated protein 2 (KCP2), subunits of the oligosaccharyltransferase complex, are regulators of the gamma-secretase-directed processing of amyloid precursor protein (APP)
    Cornelia M Wilson
    Universite de Limoges, Groupe de Neurobiologie Cellulaire EA3842 Homéostasie cellulaire et pathologies, Faculte de Medecine, 2 Rue du Dr Raymond Marcland, 87025 Limoges Cedex, France
    J Biol Chem 286:31080-91. 2011
    ..Our findings reveal that components of the OST complex for the first time can interact with the γ-secretase and affect the APP processing pathway...
  15. ncbi request reprint Tau phosphorylation and neuronal apoptosis induced by the blockade of PP2A preferentially involve GSK3β
    Ludovic Martin
    Groupe de Neurobiologie Cellulaire EA3842, Homéostasie Cellulaire et Pathologies, Faculte de Medecine, 2 Rue du Dr Raymond Marcland, 87025 Limoges Cedex, France
    Neurochem Int 59:235-50. 2011
    ..We show that 6-BIBEO efficiently reversed OKA-induced tau phosphorylation and neuronal apoptosis. It will be interesting to test neuroprotection by 6-BIBEO in an in vivo model of tau pathology and neurodegeneration...
  16. ncbi request reprint "Cri-du-chat" syndrome in a patient born to a mother with a paracentric inversion of chromosome 5q
    Sylvie Bourthoumieu
    Faculte de Medecine, Laboratoire d Histologie et de Cytogénétique, 2, rue du Dr Marcland, 87025 Limoges, France
    Ann Genet 46:483-6. 2003
    ..Therefore, as might have been expected, maternal paracentric inversion of chromosome 5q and "cri-du-chat syndrome" presented by the daughter were not related...
  17. ncbi request reprint Two unusual chromosome aberrations ascertained by sonographic anomalies
    Sylvie Bourthoumieu
    Department of Histology and Cytogenetics, Limoges University Hospital, Faculty of Medicine, Limoges, France
    Prenat Diagn 24:219-23. 2004
    ..These two cases illustrate the role of ultrasound in leading to detection not only of foetal chromosomal aberrations but also of rare balanced chromosomal rearrangements presented by one of the two parents...
  18. ncbi request reprint Study of p53 expression and post-transcriptional modifications after GSM-900 radiofrequency exposure of human amniotic cells
    Sylvie Bourthoumieu
    Department of Histology and Cytogenetics, Limoges University Hospital, Limoges Cedex, France
    Bioelectromagnetics 34:52-60. 2013
    ....
  19. ncbi request reprint Autophagy dysfunction and its link to Alzheimer's disease and type II diabetes mellitus
    Cornelia M Wilson
    Groupe de Neurobiologie Cellulaire EA3842 Homéostasie cellulaire et pathologies, Universite de Limoges, Faculté de Médecine 2, rue du Dr Raymond Marcland, 87025 Limoges Cedex, France
    CNS Neurol Disord Drug Targets 13:226-46. 2014
    ..Hence, in a last part we will discuss the possible interventions susceptible to combat both T2DM and AD. ..
  20. ncbi request reprint Brefeldin A induces apoptosis and cell cycle blockade in glioblastoma cell lines
    Isabelle Pommepuy
    Department of Pathology, Limoges University Hospital, Faculty of Medicine, Limoges, France
    Oncology 64:459-67. 2003
    ..Our results suggest that BFA may be a potent cell cycle modulator and inducer of apoptosis in GB cell lines, and therefore may become a promising candidate for the chemotherapeutic treatment of gliomas...
  21. ncbi request reprint Post-translational modifications of tau protein: implications for Alzheimer's disease
    Ludovic Martin
    Groupe de Neurobiologie Cellulaire EA3842 Homéostasie cellulaire et pathologies, Faculte de Medecine, Limoges, France
    Neurochem Int 58:458-71. 2011
    ....
  22. ncbi request reprint Induction of antiproliferative effect by diosgenin through activation of p53, release of apoptosis-inducing factor (AIF) and modulation of caspase-3 activity in different human cancer cells
    Cecile Corbiere
    Laboratoire de Biochimie, UPRES EA 1085, Faculte de Pharmacie, 2 rue du Docteur Marcland, 87025 Limoges Cedex, France
    Cell Res 14:188-96. 2004
    ..Diosgenin treatment also induces p53 activation and cell cycle arrest in the different cell lines studied...