Gilles Pernod

Summary

Affiliation: CHU de Grenoble
Country: France

Publications

  1. doi request reprint French clinical practice guidelines on the management of patients on vitamin K antagonists in at-risk situations (overdose, risk of bleeding, and active bleeding)
    Gilles Pernod
    Vascular Medical unit, CHU Grenoble, Grenoble
    Thromb Res 126:e167-74. 2010
  2. doi request reprint Management of major bleeding complications and emergency surgery in patients on long-term treatment with direct oral anticoagulants, thrombin or factor-Xa inhibitors: proposals of the working group on perioperative haemostasis (GIHP) - March 2013
    Gilles Pernod
    Vascular Medicine Department, University Hospital, UJF Grenoble 1 CNRS TIMC IMAG UMR 5525 Themas, France
    Arch Cardiovasc Dis 106:382-93. 2013
  3. doi request reprint [Questions--answers on the use of rivaroxaban for the treatment of venous thromboembolic disease]
    G Pernod
    Département de médecine vasculaire, UJF Grenoble 1 CNRS TIMC IMAG UMR 5525 Themas, CHU de Grenoble, BP 217, 38043 Grenoble Cedex 9, France
    J Mal Vasc 37:300-10. 2012
  4. pmc EDUC'AVK: reduction of oral anticoagulant-related adverse events after patient education: a prospective multicenter open randomized study
    Gilles Pernod
    Department of Vascular Medicine, CHU Grenoble, Grenoble, France
    J Gen Intern Med 23:1441-6. 2008
  5. ncbi request reprint Surgery in severe factor XIII deficiency: report of a case of epilepsy neurosurgery and review
    G Pernod
    Haemostasis Unit, CHL1, Grendale, France
    Haemophilia 9:121-4. 2003
  6. ncbi request reprint [Routine preoperative evaluation of hemostasis]
    G Pernod
    Unite d hémostase, DBPC, CHU Grenoble, BP 217X, 38043 Grenoble Cedex 9
    Rev Stomatol Chir Maxillofac 104:91-7. 2003
  7. doi request reprint Outcomes for inpatients with normal findings on whole-leg ultrasonography: a prospective study
    Marie Antoinette Sevestre
    Techniques de l Ingénierie Médicale et de la Complexité, Unité Mixte de Recherche 5525, Centre National de la Recherche Scientifique, Universite Joseph Fourier, Grenoble, France Vascular Medicine Unit, Amiens University Hospital, Amiens, France
    Am J Med 123:158-65. 2010
  8. doi request reprint Surgery and invasive procedures in patients on long-term treatment with direct oral anticoagulants: thrombin or factor-Xa inhibitors. Recommendations of the Working Group on Perioperative Haemostasis and the French Study Group on Thrombosis and Haemostasi
    Pierre Sie
    Haematology Department, University Hospital, Toulouse 31059, France
    Arch Cardiovasc Dis 104:669-76. 2011
  9. doi request reprint [Therapy education for patients receiving oral anti-coagulants vitamin K antagonists]
    Bernadette Satger
    Réseau ville hôpital Granted, Grenoble, F 38400 ST Martin D Hères, France
    Presse Med 38:1780-7. 2009
  10. doi request reprint Effect of non-specific reversal agents on anticoagulant activity of dabigatran and rivaroxaban: a randomised crossover ex vivo study in healthy volunteers
    Raphaël Marlu
    Haemostasis Unit, University Hospital Grenoble, France
    Thromb Haemost 108:217-24. 2012

Collaborators

Detail Information

Publications27

  1. doi request reprint French clinical practice guidelines on the management of patients on vitamin K antagonists in at-risk situations (overdose, risk of bleeding, and active bleeding)
    Gilles Pernod
    Vascular Medical unit, CHU Grenoble, Grenoble
    Thromb Res 126:e167-74. 2010
    ....
  2. doi request reprint Management of major bleeding complications and emergency surgery in patients on long-term treatment with direct oral anticoagulants, thrombin or factor-Xa inhibitors: proposals of the working group on perioperative haemostasis (GIHP) - March 2013
    Gilles Pernod
    Vascular Medicine Department, University Hospital, UJF Grenoble 1 CNRS TIMC IMAG UMR 5525 Themas, France
    Arch Cardiovasc Dis 106:382-93. 2013
    ....
  3. doi request reprint [Questions--answers on the use of rivaroxaban for the treatment of venous thromboembolic disease]
    G Pernod
    Département de médecine vasculaire, UJF Grenoble 1 CNRS TIMC IMAG UMR 5525 Themas, CHU de Grenoble, BP 217, 38043 Grenoble Cedex 9, France
    J Mal Vasc 37:300-10. 2012
    ..This report addresses the use of rivaroxaban in clinical practice in such indications...
  4. pmc EDUC'AVK: reduction of oral anticoagulant-related adverse events after patient education: a prospective multicenter open randomized study
    Gilles Pernod
    Department of Vascular Medicine, CHU Grenoble, Grenoble, France
    J Gen Intern Med 23:1441-6. 2008
    ..Insufficient patient education is linked to poorly controlled anticoagulation. However the impact of a specific educational program on anticoagulation related morbidity remains unknown...
  5. ncbi request reprint Surgery in severe factor XIII deficiency: report of a case of epilepsy neurosurgery and review
    G Pernod
    Haemostasis Unit, CHL1, Grendale, France
    Haemophilia 9:121-4. 2003
    ..We report here an epilepsy neurosurgery in a case of severe FXIII deficiency...
  6. ncbi request reprint [Routine preoperative evaluation of hemostasis]
    G Pernod
    Unite d hémostase, DBPC, CHU Grenoble, BP 217X, 38043 Grenoble Cedex 9
    Rev Stomatol Chir Maxillofac 104:91-7. 2003
    ..Applied in an informative population, clinical evaluation enables optimal utilization of laboratory results...
  7. doi request reprint Outcomes for inpatients with normal findings on whole-leg ultrasonography: a prospective study
    Marie Antoinette Sevestre
    Techniques de l Ingénierie Médicale et de la Complexité, Unité Mixte de Recherche 5525, Centre National de la Recherche Scientifique, Universite Joseph Fourier, Grenoble, France Vascular Medicine Unit, Amiens University Hospital, Amiens, France
    Am J Med 123:158-65. 2010
    ..This study aimed to estimate the rate of venous thromboembolism when anticoagulant therapy was withheld from inpatients with normal findings on whole-leg ultrasonography...
  8. doi request reprint Surgery and invasive procedures in patients on long-term treatment with direct oral anticoagulants: thrombin or factor-Xa inhibitors. Recommendations of the Working Group on Perioperative Haemostasis and the French Study Group on Thrombosis and Haemostasi
    Pierre Sie
    Haematology Department, University Hospital, Toulouse 31059, France
    Arch Cardiovasc Dis 104:669-76. 2011
    ....
  9. doi request reprint [Therapy education for patients receiving oral anti-coagulants vitamin K antagonists]
    Bernadette Satger
    Réseau ville hôpital Granted, Grenoble, F 38400 ST Martin D Hères, France
    Presse Med 38:1780-7. 2009
    ..This approach makes it possible to adapt the educational message to individual patients and their daily lives, as well as directly involving them in the management of their treatment...
  10. doi request reprint Effect of non-specific reversal agents on anticoagulant activity of dabigatran and rivaroxaban: a randomised crossover ex vivo study in healthy volunteers
    Raphaël Marlu
    Haemostasis Unit, University Hospital Grenoble, France
    Thromb Haemost 108:217-24. 2012
    ..However, clinical evaluation is needed regarding haemorrhagic situations, and a meticulous risk-benefit evaluation regarding their use in this context is required...
  11. doi request reprint Low-molecular-weight heparin prophylaxis of deep vein thrombosis for older patients with restricted mobility: propensity analyses of data from two multicentre, cross-sectional studies
    Jose Labarere
    Quality of Care Unit, Grenoble University Hospital, Grenoble, France
    Drugs Aging 26:263-71. 2009
    ..Although older patients with restricted mobility are at increased risk for venous thromboembolism, they are under-represented in clinical trials evaluating prophylactic treatments against deep vein thrombosis (DVT)...
  12. ncbi request reprint Cardiovascular mortality and C-reactive protein in elderly patients beginning dialysis: reverse epidemiology?
    Claire Millet
    Geriatric University Clinic, University Hospital of Grenoble, BP 217, 38043 Grenoble Cedex 9, Grenoble, France
    Aging Clin Exp Res 23:357-63. 2011
    ..The aim of this study was to examine whether, in elderly ESRD patients, the conventional relationship between elevated CRP and cardiovascular mortality is maintained...
  13. doi request reprint Accuracy of complete compression ultrasound in ruling out suspected deep venous thrombosis in the ambulatory setting. A prospective cohort study
    Marie Antoinette Sevestre
    ThEMAS, TIMC UMR 5525 CNRS Université Joseph Fourier, Grenoble, France
    Thromb Haemost 102:166-72. 2009
    ..6%, 95% CI, 0.3-1.2) died during the three-month follow-up. In conclusion, anticoagulant therapy can be safely withheld after negative complete compression ultrasound without further testing in the ambulatory office setting...
  14. ncbi request reprint FVIIa corrects the coagulopathy of fulminant hepatic failure but may be associated with thrombosis: a report of four cases
    Patricia Pavese
    Department of Reanimation Medicale, CHU de Grenoble, Grenoble, France
    Can J Anaesth 52:26-9. 2005
    ..Recombinant activated factor VII (rFVIIa) has shown promise in treating the coagulopathy of liver disease. We review our experience with the use of rFVIIa in treating the coagulopathy of FHF during urgent liver transplantation...
  15. doi request reprint Non-severe pulmonary embolism: prognostic CT findings
    Anne Line Moroni
    University J Fourrier, Grenoble, France
    Eur J Radiol 79:452-8. 2011
    ..Concomitant lower limb DVT and comorbid conditions were important predictors of death. In clinically non-severe PE, a RV/LV diameter ratio >1 is predictive of death when the embolic burden is low (< 40%)...
  16. doi request reprint Should plasma homocysteine be used as a biomarker of venous thromboembolism? A case-control study
    Veronique Ducros
    Département de Biologie Intégrée Centre Hospitalier Universitaire, BP 217 X, 38043 Grenoble Cedex 9, France
    Clin Appl Thromb Hemost 15:517-22. 2009
    ..Mild or moderate hyperhomocysteinemia does not seem to be a strong determinant in VTE not only when the control group does not exclusively include healthy persons but also in investigated disease-free (thromboembolic disease) controls...
  17. pmc Brief report: graduated compression stocking thromboprophylaxis for elderly inpatients: a propensity analysis
    Jose Labarere
    ThEMAS TIMC IMAG UMR CNRS 5525 UJF, Grenoble, France
    J Gen Intern Med 21:1282-7. 2006
    ..Graduated compression stockings (GCS) are often used for deep vein thrombosis prophylaxis in nonsurgical patients, although evidence on their effectiveness is lacking in this setting...
  18. ncbi request reprint The Diamant Alpin Dialysis cohort study: clinico-biological characteristics and cardiovascular genetic risk profile of incident patients
    Gilles Pernod
    CHU Grenoble, France
    J Nephrol 17:66-75. 2004
    ....
  19. ncbi request reprint Successful use of recombinant factor VIIa for severe surgical liver bleeding in a 5 month-old baby
    C Barro
    Cell Biology and Pathology Department Child Intensive Care Unit, CHU Grenoble, France
    Haemophilia 10:183-5. 2004
    ..A single recombinant activated factor VII injection following enlarged hepatectomy helped to resolve quickly this life-threatening haemorrhagic syndrome...
  20. ncbi request reprint Validation of a clinical guideline on prevention of venous thromboembolism in medical inpatients: a before-and-after study with systematic ultrasound examination
    J Labarere
    Unite d Evaluation Medicale, Pavillon D, Centre Hospitalier Universitaire de Grenoble, 38 043 Grenoble Cedex 9, France
    J Intern Med 256:338-48. 2004
    ..Clinical practice guidelines on prevention of venous thromboembolism in medical inpatients have been implemented in various settings, although few studies have assessed their impact on venous thromboembolism events...
  21. ncbi request reprint Analysis of biological phenotypes from 42 patients with inherited factor VII deficiency: can biological tests predict the bleeding risk?
    Muriel Giansily-Blaizot
    Laboratory of Haematology, CHU Montpellier, France
    Haematologica 89:704-9. 2004
    ..Our study was aimed at defining biological parameters that are possibly predictive for bleeding risk in this condition...
  22. ncbi request reprint More on: incorrect use of thromboprophylaxis for venous thromboembolism in medical and surgical patients: results of a multicentric, observational, and cross-sectional study in Brazil
    J Labarere
    J Thromb Haemost 4:2737-8. 2006
  23. ncbi request reprint [Thromboprohylaxis in orthopedic surgery and traumatology]
    P Mismetti
    Unité de pharmacologie clinique EA 3065, CIE 3n, Service de Médecine Interne et Thérapeutique, Hopital Bellevue, CHU, Saint Etienne, France
    Ann Fr Anesth Reanim 24:871-89. 2005
    ..But LMWH has to be considered for patients with additional risk factors. Prophylaxis in other orthopedic procedures has not been assessed and will be extrapolated from the above recommendations...
  24. ncbi request reprint More on: asymptomatic thrombophilia--a family affair
    G Pernod
    J Thromb Haemost 3:1329-30. 2005
  25. ncbi request reprint More on: a survey of thrombosis prophylaxis use in patients undergoing arthroscopic surgery
    G Pernod
    J Thromb Haemost 3:1115-6. 2005
  26. ncbi request reprint Quantitative high D-dimer value is predictive of pulmonary embolism occurrence independently of clinical score in a well-defined low risk factor population
    J L Bosson
    Hemostasis Unit, DBPC, Grenoble, France
    J Thromb Haemost 3:93-9. 2005
    ..A clinical validation of these results in a follow-up study would now be necessary before considering the implementation of this strategy into clinical practice...
  27. ncbi request reprint Non-conform diagnostic management of pulmonary embolism suspected patients is responsible for a higher risk of thrombotic event occurrence
    J L Bosson
    Center of Clinical Investigation, CHU de Grenoble, BP 217, 38043 Grenoble Cedex 9, France
    J Mal Vasc 32:15-22. 2007
    ..3 [1.1-10, 95% CI]. Therefore we demonstrated that a non-conform diagnostic management strategy is associated with a higher risk of thrombotic event occurrence...