J J Parienti

Summary

Affiliation: CHU de Caen
Country: France

Publications

  1. pmc Methodological standards in non-inferiority AIDS trials: moving from adherence to compliance
    Jean Jacques Parienti
    Inserm UMR S 707, Paris, F 75012, Universite Pierre et Marie Curie PARIS6, UMR S 707, Paris, F 75012, France
    BMC Med Res Methodol 6:46. 2006
  2. pmc Not all missed doses are the same: sustained NNRTI treatment interruptions predict HIV rebound at low-to-moderate adherence levels
    Jean Jacques Parienti
    Clinical Research and Biostatistics Department, Cote de Nacre University Hospital, Caen, France
    PLoS ONE 3:e2783. 2008
  3. pmc Pharmacologic boosting of atazanavir in maintenance HIV-1 therapy: the COREYA propensity-score adjusted study
    Laurent Hocqueloux
    Service des Maladies Infectieuses et Tropicales, Centre Hospitalier Regional, Orleans, France
    PLoS ONE 7:e49289. 2012
  4. ncbi request reprint Meta-analysis of subclavian insertion and nontunneled central venous catheter-associated infection risk reduction in critically ill adults
    Jean Jacques Parienti
    Biostatistics and Clinical Research Unit, Department of Medical Intensive Care, CHU Caen, Université Caen, Caen, France
    Crit Care Med 40:1627-34. 2012
  5. pmc Predictors of mortality and short-term physical and cognitive dependence in critically ill persons 75 years and older: a prospective cohort study
    Cedric Daubin
    Department of Medical Intensive Care, Avenue Cote de Nacre, Caen University Hospital, 14033 Caen Cedex, France
    Health Qual Life Outcomes 9:35. 2011
  6. pmc Epidemiology and clinical outcome of virus-positive respiratory samples in ventilated patients: a prospective cohort study
    Cedric Daubin
    Department of Medical Intensive Care, Avenue Cote de Nacre, Caen University Hospital, 14033 Caen Cedex, France
    Crit Care 10:R142. 2006
  7. pmc Mild hypothermia during advanced life support: a preliminary study in out-of-hospital cardiac arrest
    Cédric Bruel
    Medical Intensive Care Unit, Caen University Hospital, Avenue Cote de Nacre, 14033 Caen Cedex, France
    Crit Care 12:R31. 2008
  8. pmc Procalcitonin levels in acute exacerbation of COPD admitted in ICU: a prospective cohort study
    Cedric Daubin
    Department of Medical Intensive Care, Caen University Hospital, 14033 Caen Cedex, France
    BMC Infect Dis 8:145. 2008
  9. pmc Procalcitonin levels and bacterial aetiology among COPD patients admitted to the ICU with severe pneumonia: a prospective cohort study
    Cedric Daubin
    The Department of Medical Intensive Care, Caen University Hospital, 14033 Caen Cedex, France
    BMC Infect Dis 9:157. 2009
  10. pmc Serum neuron-specific enolase as predictor of outcome in comatose cardiac-arrest survivors: a prospective cohort study
    Cedric Daubin
    Department of Medical Intensive Care, CHU de Caen, Caen, F 14000, France
    BMC Cardiovasc Disord 11:48. 2011

Detail Information

Publications44

  1. pmc Methodological standards in non-inferiority AIDS trials: moving from adherence to compliance
    Jean Jacques Parienti
    Inserm UMR S 707, Paris, F 75012, Universite Pierre et Marie Curie PARIS6, UMR S 707, Paris, F 75012, France
    BMC Med Res Methodol 6:46. 2006
    ..It has been suggested that non-inferiority and equivalence studies are not reported with the same quantitative rigor as superiority studies...
  2. pmc Not all missed doses are the same: sustained NNRTI treatment interruptions predict HIV rebound at low-to-moderate adherence levels
    Jean Jacques Parienti
    Clinical Research and Biostatistics Department, Cote de Nacre University Hospital, Caen, France
    PLoS ONE 3:e2783. 2008
    ..We examined medication event monitoring system (MEMS) defined adherence patterns and their relation to subsequent virologic rebound...
  3. pmc Pharmacologic boosting of atazanavir in maintenance HIV-1 therapy: the COREYA propensity-score adjusted study
    Laurent Hocqueloux
    Service des Maladies Infectieuses et Tropicales, Centre Hospitalier Regional, Orleans, France
    PLoS ONE 7:e49289. 2012
    ..We evaluated the efficacy and tolerance of maintenance therapy with unboosted atazanavir in clinical practice...
  4. ncbi request reprint Meta-analysis of subclavian insertion and nontunneled central venous catheter-associated infection risk reduction in critically ill adults
    Jean Jacques Parienti
    Biostatistics and Clinical Research Unit, Department of Medical Intensive Care, CHU Caen, Université Caen, Caen, France
    Crit Care Med 40:1627-34. 2012
    ..We aimed to establish whether nontunneled central venous catheters inserted in the subclavian vein are associated with lower risk of catheter-associated infection compared to femoral or internal jugular vein insertion...
  5. pmc Predictors of mortality and short-term physical and cognitive dependence in critically ill persons 75 years and older: a prospective cohort study
    Cedric Daubin
    Department of Medical Intensive Care, Avenue Cote de Nacre, Caen University Hospital, 14033 Caen Cedex, France
    Health Qual Life Outcomes 9:35. 2011
    ....
  6. pmc Epidemiology and clinical outcome of virus-positive respiratory samples in ventilated patients: a prospective cohort study
    Cedric Daubin
    Department of Medical Intensive Care, Avenue Cote de Nacre, Caen University Hospital, 14033 Caen Cedex, France
    Crit Care 10:R142. 2006
    ..Respiratory viruses are a major cause of respiratory tract infections. The prevalence of a virus-positive respiratory sample and its significance in patients requiring mechanical ventilation remain unknown...
  7. pmc Mild hypothermia during advanced life support: a preliminary study in out-of-hospital cardiac arrest
    Cédric Bruel
    Medical Intensive Care Unit, Caen University Hospital, Avenue Cote de Nacre, 14033 Caen Cedex, France
    Crit Care 12:R31. 2008
    ..We assessed the feasibility, safety and effectiveness of therapeutic infusion of 2 l of normal saline at 4 degrees C before return of spontaneous circulation during cardiopulmonary resuscitation after out of hospital cardiac arrest...
  8. pmc Procalcitonin levels in acute exacerbation of COPD admitted in ICU: a prospective cohort study
    Cedric Daubin
    Department of Medical Intensive Care, Caen University Hospital, 14033 Caen Cedex, France
    BMC Infect Dis 8:145. 2008
    ..Serum procalcitonin (PCT) could be a useful tool for selecting patients with a lower probability of developing bacterial infection, but its measurement has not been investigated in this population...
  9. pmc Procalcitonin levels and bacterial aetiology among COPD patients admitted to the ICU with severe pneumonia: a prospective cohort study
    Cedric Daubin
    The Department of Medical Intensive Care, Caen University Hospital, 14033 Caen Cedex, France
    BMC Infect Dis 9:157. 2009
    ..In this study, we describe PCT levels overtime and their relationship with bacterial infection in chronic obstructive pulmonary disease (COPD) critically ill patients with pneumonia...
  10. pmc Serum neuron-specific enolase as predictor of outcome in comatose cardiac-arrest survivors: a prospective cohort study
    Cedric Daubin
    Department of Medical Intensive Care, CHU de Caen, Caen, F 14000, France
    BMC Cardiovasc Disord 11:48. 2011
    ..The purpose of this study was to assess the capability of serum neuron-specific enolase (NSE), a biomarker of hypoxic brain damage, to predict death or vegetative state in comatose cardiac-arrest survivors...
  11. pmc A clinical and EEG scoring system that predicts early cortical response (N20) to somatosensory evoked potentials and outcome after cardiac arrest
    Cedric Daubin
    Department of Medical Intensive Care, Caen University Hospital, Caen, France
    BMC Cardiovasc Disord 8:35. 2008
    ..The aim of the current research was to construct a clinical and EEG scoring system that predicts early cortical response (N20) to somatosensory evoked potentials and 6-months outcome in comatose patients after cardiac arrest...
  12. ncbi request reprint Predictors of virologic failure and resistance in HIV-infected patients treated with nevirapine- or efavirenz-based antiretroviral therapy
    Jean Jacques Parienti
    Department of Infectious Diseases and Virology, Côte de Nacre Hospital, Caen, France
    Clin Infect Dis 38:1311-6. 2004
    ..8-180.3; P<.0001). Patients' previous adherence to therapy and drugs genetic barriers, not only the number of pills or doses involved, should be taken into consideration in the decision to simplify highly active antiretroviral therapy...
  13. doi request reprint Femoral vs jugular venous catheterization and risk of nosocomial events in adults requiring acute renal replacement therapy: a randomized controlled trial
    Jean Jacques Parienti
    Department of Biostatistics and Clinical Research, Côte de Nacre University Hospital Center, Ave de la Côte de Nacre, 14033 Caen Cedex, France
    JAMA 299:2413-22. 2008
    ..Based on concerns about the risk of infection, the jugular site is often preferred over the femoral site for short-term dialysis vascular access...
  14. ncbi request reprint Effect of twice-daily nevirapine on adherence in HIV-1-infected patients: a randomized controlled study
    Jean Jacques Parienti
    INSERM U707, Epidemiologie, Systemes d Informations, Modelisation, Paris, F 75012, France
    AIDS 21:2217-22. 2007
    ..For optimal adherence, once-daily dosing is best. Whether this applies to antiretroviral therapy is unknown. We thus aimed to determine the effect of once-daily dosing on adherence to nevirapine...
  15. ncbi request reprint Efavirenz to nevirapine switch in HIV-1-infected patients with dyslipidemia: a randomized, controlled study
    Jean Jacques Parienti
    Epidemiologie, Systemes d Informations, Modelisation, Institut National de la Sante et de la Recherche Medicale U707, Paris, France
    Clin Infect Dis 45:263-6. 2007
    ..04). A switch to nevirapine was associated with no severe adverse events...
  16. pmc Better adherence with once-daily antiretroviral regimens: a meta-analysis
    Jean Jacques Parienti
    Department of Biostatistics and Clinical Research, Cote de Nacre University Hospital, Caen, France
    Clin Infect Dis 48:484-8. 2009
    ..9%; 95% confidence interval, 1.0%-4.8%; P < .003) than with twice-daily regimens. This modest effect was more pronounced at the time of treatment initiation and for regimens for which all medications were taken once per day...
  17. ncbi request reprint Cluster-crossover design: a method for limiting clusters level effect in community-intervention studies
    Jean Jacques Parienti
    Department of Biostatistics and Clinical Research, Côte de Nacre University of Medicine, 14033 Caen, France
    Contemp Clin Trials 28:316-23. 2007
    ..Original data from two published field studies of hospital infection control based on this design are used here to illustrate the impact of different statistical models on the interpretation of the results...
  18. doi request reprint [Nevirapine and cardiovascular risk]
    J J Parienti
    Service des Maladies Infectieuses et Tropicales, CHU Cote de Nacre, Avenue de la Cote de Nacre, 14033 Caen, France
    Med Mal Infect 40:499-505. 2010
    ..This data should be considered when choosing antiretroviral treatment, especially for initiation of treatment in patients with cardiovascular risk factors or when substituting for an efficient tritherapy...
  19. doi request reprint Nevirapine once daily: pharmacology, metabolic profile and efficacy data of the new extended-release formulation
    Jean Jacques Parienti
    Department of Biostatistics and Clinical Research, Côte de Nacre Univ Hosp, Avenue de la Cote de Nacre, 14033 Caen, France
    Expert Opin Drug Metab Toxicol 7:495-503. 2011
    ..Currently, twice-a-day dosing is required for the successful application of NVP immediate release (IR), but there is potential for a more convenient once-a-day antiretroviral combination...
  20. doi request reprint Hospital-wide modification of fluoroquinolone policy and meticillin-resistant Staphylococcus aureus rates: a 10-year interrupted time-series analysis
    J J Parienti
    Department of Biostatistics and Clinical Research, CHU de Caen, Caen, France
    J Hosp Infect 78:118-22. 2011
    ..This study reinforces the rationale for a hospital-wide fluoroquinolone formulary policy to control MRSA and suggests that it has an additive effect with a hand hygiene promotion...
  21. doi request reprint Catheter dysfunction and dialysis performance according to vascular access among 736 critically ill adults requiring renal replacement therapy: a randomized controlled study
    Jean Jacques Parienti
    Department of Biostatistics and Clinical Research, Côte de Nacre University Hospital Center, Caen, France
    Crit Care Med 38:1118-25. 2010
    ..To compare dialysis catheter function according to catheter site...
  22. pmc Continuous renal replacement therapy may increase the risk of catheter infection
    Jean Jacques Parienti
    Biostatistics and Clinical Research, Cote de Nacre University Hospital, Caen, France
    Clin J Am Soc Nephrol 5:1489-96. 2010
    ..We compared the two modalities among critically ill adults requiring acute renal replacement therapy (RRT)...
  23. ncbi request reprint [Multicenter survey on ventilator-associated pneumonia prevention in intensive care]
    M O Fischer
    Pôle réanimations anesthésie Samu Smur, CHU de Caen, Avenue de la Cote de Nacre, CS 30001, 14000 Caen, France EA 4650, Universite de Caen Basse Normandie, Esplanade de la Paix, CS 14032, 14000 Caen, France Electronic address
    Ann Fr Anesth Reanim 32:833-7. 2013
    ..Ventilator-associated pneumonia (VAP) is the most common hospital-acquired infection in intensive care unit (ICU). The aim of the study was to evaluate the follow-up of the guidelines for VAP prevention...
  24. ncbi request reprint [Fluoroquinolone use and MRSA rates in hospitalized patients]
    P Charbonneau
    CHU Cote de Nacre, 14033 Caen Cedex, France
    Med Mal Infect 35:S35-7. 2005
  25. doi request reprint A randomized trial of two-drug versus three-drug tenofovir-containing maintenance regimens in virologically controlled HIV-1 patients
    Pierre Marie Girard
    Service des Maladies Infectieuses et Tropicales, Hopital Saint Antoine, Assistance Publique Hopitaux de Paris, Universite Paris VI, Paris, France
    J Antimicrob Chemother 64:126-34. 2009
    ..To assess simplified maintenance regimens containing dual antiretroviral drugs in patients with controlled human immunodeficiency virus type 1 infection...
  26. ncbi request reprint Cytokine therapy or structured treatment interruptions in HIV infection: which is best?
    Jean Jacques Parienti
    Service de Maladies Infectieuses et Reanimation Medicale, Hôpital Côte de Nacre, Caen, France
    Expert Opin Pharmacother 3:719-26. 2002
    ..Ongoing and future clinical trials will provide a rationale for their use in clinical practice and will determine how these strategies can be combined to optimise HAART...
  27. ncbi request reprint Nosocomial viral ventilator-associated pneumonia in the intensive care unit: a prospective cohort study
    Cedric Daubin
    Department of Medical Intensive Care, Caen University Hospital, 14033, Caen Cedex, France
    Intensive Care Med 31:1116-22. 2005
    ..To determine the incidence, risk factors, and clinical relevance of viral ventilator-associated pneumonia (VAP) in an adult intensive care unit (ICU)...
  28. ncbi request reprint Alcoholic povidone-iodine to prevent central venous catheter colonization: A randomized unit-crossover study
    Jean Jacques Parienti
    Departments of Medical Intensive Care Unit, Cote de Nacre University Hospital, Caen, France
    Crit Care Med 32:708-13. 2004
    ..To compare effectiveness in preventing central venous catheter colonization and infection of two protocols of cutaneous antisepsis using povidone-iodine solution in combination with ethanol or water...
  29. ncbi request reprint Impact of anemia on outcome in critically ill patients with severe acute renal failure
    Damien du Cheyron
    Department of Medical Intensive Care, Caen University Hospital, av Côte de Nacre, 14033, Caen Cedex, France
    Intensive Care Med 31:1529-36. 2005
    ..To evaluate the prognostic value of hemoglobin levels in critically ill patients with acute renal failure (ARF) requiring dialysis...
  30. ncbi request reprint The attributable mortality of acute renal failure in critically ill patients with liver cirrhosis
    Damien du Cheyron
    Department of Medical Intensive Care, Caen University Hospital, av Côte de Nacre, 14033, Caen Cedex, France
    Intensive Care Med 31:1693-9. 2005
    ..To determine outcome and mortality risk related to acute renal failure (ARF) in critically ill patients with cirrhosis...
  31. ncbi request reprint Fluoroquinolone use and methicillin-resistant Staphylococcus aureus isolation rates in hospitalized patients: a quasi experimental study
    Pierre Charbonneau
    Department of Medical Intensive Care Unit, Cote de Nacre University Hospital, Caen, France
    Clin Infect Dis 42:778-84. 2006
    ..We investigated the possible association between fluoroquinolone use and the rate of methicillin-resistant Staphylococcus aureus (MRSA) recovery from consecutive hospitalized patients...
  32. ncbi request reprint Vertebral osteomyelitis due to Bartonella henselae in adults: a report of 2 cases
    Renaud Verdon
    Service de Maladies Infectieuses et Tropicales, Centre Hospitalier Universitaire Côte de Nacre, 14033 Caen Cedex, France
    Clin Infect Dis 35:e141-4. 2002
    ..Diagnosis was established on the basis of direct identification of the microorganism in one case and seroconversion in the other. Both patients recovered completely within 3 months...
  33. doi request reprint Oral thromboprophylaxis following total hip replacement: the issue of compliance
    B Lebel
    Caen University Hospital Center, Orthopedics Department, Avenue de la Cote de Nacre, 14000 Caen, France
    Orthop Traumatol Surg Res 98:186-92. 2012
    ....
  34. doi request reprint An information campaign on aminoglycosides use during septic shock failed to improve the quality of care
    M O Fischer
    Pôle anesthésie réanimation Samu Smur coordination hospitalière hémovigilance, CHU de Caen, France
    Ann Fr Anesth Reanim 31:e1-5. 2012
    ..The aim of the study was to assess the impact of an information campaign on modalities of prescription of aminoglycosides in septic shock...
  35. doi request reprint Switching the nucleoside reverse transcriptase inhibitor backbone to tenofovir disoproxil fumarate + emtricitabine promptly improves triglycerides and low-density lipoprotein cholesterol in dyslipidaemic patients
    M A Valantin
    Department of Infectious Diseases, AP HP, Pitie Salpetriere Hospital, Paris, France
    J Antimicrob Chemother 65:556-61. 2010
    ..To assess the impact of switching to tenofovir disoproxil fumarate + emtricitabine on lipid parameters...
  36. ncbi request reprint [Epidemiology of candidemia: a one-year prospective observational study in the west of France]
    J P Talarmin
    Service des Maladies Infectieuses et Tropicales, CHU Hotel Dieu, Nantes Cedex 1, France
    Med Mal Infect 39:877-85. 2009
    ..A one-year prospective, observational study was conducted in the west of France, to evaluate the epidemiology of candidemia...
  37. ncbi request reprint Predictors of virological rebound in the APROCO cohort study
    Jean Jacques Parienti
    AIDS 16:2369. 2002
  38. doi request reprint Perioperative use of dobutamine in cardiac surgery and adverse cardiac outcome: propensity-adjusted analyses
    Jean Luc Fellahi
    Centre Hospitalier Privé Saint Martin, Caen Université Pierre et Marie Curie Paris 6, EA3975, Paris
    Anesthesiology 108:979-87. 2008
    ..The current study assessed the consequences on clinical outcome of catecholamines simply based on the clinical judgment of the anesthesiologists after cardiopulmonary bypass in adult cardiac surgery...
  39. ncbi request reprint Knowledge of and adherence to antiretroviral therapy
    Jean Jacques Parienti
    Clin Infect Dis 37:861-2; author reply 862-3. 2003
  40. ncbi request reprint Tenofovir, equivalence, and noninferiority
    Jean Jacques Parienti
    JAMA 292:1951; author reply 1951-2. 2004
  41. ncbi request reprint Quality of care and satisfaction among patients isolated for infection control
    Jean Jacques Parienti
    JAMA 291:420; author reply 421-2. 2004
  42. ncbi request reprint Treatment resistance after sequential interruption of a non-nucleoside reverse transcriptase inhibitor-based regimen
    Sylvie Dargere
    AIDS 21:879-80. 2007
  43. ncbi request reprint Viral pneumonia and respiratory sepsis: association, causation, or it depends?
    Jean Jacques Parienti
    Crit Care Med 35:639-40. 2007
  44. ncbi request reprint Intravenous drug users risk group should also benefit from simpler highly active antiretroviral therapy
    Jean Jacques Parienti
    AIDS 16:2097; author reply 2098. 2002