Research Topics
| J J ParientiSummaryAffiliation: CHU de Caen Country: France Publications
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Detail Information
Publications
Methodological standards in non-inferiority AIDS trials: moving from adherence to complianceJean Jacques Parienti
Inserm UMR S 707, Paris, F 75012, Universite Pierre et Marie Curie PARIS6, UMR S 707, Paris, F 75012, France
BMC Med Res Methodol 6:46. 2006..It has been suggested that non-inferiority and equivalence studies are not reported with the same quantitative rigor as superiority studies...
Not all missed doses are the same: sustained NNRTI treatment interruptions predict HIV rebound at low-to-moderate adherence levelsJean Jacques Parienti
Clinical Research and Biostatistics Department, Cote de Nacre University Hospital, Caen, France
PLoS ONE 3:e2783. 2008..We examined medication event monitoring system (MEMS) defined adherence patterns and their relation to subsequent virologic rebound...
Meta-analysis of subclavian insertion and nontunneled central venous catheter-associated infection risk reduction in critically ill adultsJean Jacques Parienti
Biostatistics and Clinical Research Unit, Department of Medical Intensive Care, CHU Caen, Université Caen, Caen, France
Crit Care Med 40:1627-34. 2012..We aimed to establish whether nontunneled central venous catheters inserted in the subclavian vein are associated with lower risk of catheter-associated infection compared to femoral or internal jugular vein insertion...
Predictors of mortality and short-term physical and cognitive dependence in critically ill persons 75 years and older: a prospective cohort studyCedric Daubin
Department of Medical Intensive Care, Avenue Cote de Nacre, Caen University Hospital, 14033 Caen Cedex, France
Health Qual Life Outcomes 9:35. 2011....
Epidemiology and clinical outcome of virus-positive respiratory samples in ventilated patients: a prospective cohort studyCedric Daubin
Department of Medical Intensive Care, Avenue Cote de Nacre, Caen University Hospital, 14033 Caen Cedex, France
Crit Care 10:R142. 2006..Respiratory viruses are a major cause of respiratory tract infections. The prevalence of a virus-positive respiratory sample and its significance in patients requiring mechanical ventilation remain unknown...
Mild hypothermia during advanced life support: a preliminary study in out-of-hospital cardiac arrestCédric Bruel
Medical Intensive Care Unit, Caen University Hospital, Avenue Cote de Nacre, 14033 Caen Cedex, France
Crit Care 12:R31. 2008..We assessed the feasibility, safety and effectiveness of therapeutic infusion of 2 l of normal saline at 4 degrees C before return of spontaneous circulation during cardiopulmonary resuscitation after out of hospital cardiac arrest...
Procalcitonin levels in acute exacerbation of COPD admitted in ICU: a prospective cohort studyCedric Daubin
Department of Medical Intensive Care, Caen University Hospital, 14033 Caen Cedex, France
BMC Infect Dis 8:145. 2008..Serum procalcitonin (PCT) could be a useful tool for selecting patients with a lower probability of developing bacterial infection, but its measurement has not been investigated in this population...
Procalcitonin levels and bacterial aetiology among COPD patients admitted to the ICU with severe pneumonia: a prospective cohort studyCedric Daubin
The Department of Medical Intensive Care, Caen University Hospital, 14033 Caen Cedex, France
BMC Infect Dis 9:157. 2009..In this study, we describe PCT levels overtime and their relationship with bacterial infection in chronic obstructive pulmonary disease (COPD) critically ill patients with pneumonia...
Serum neuron-specific enolase as predictor of outcome in comatose cardiac-arrest survivors: a prospective cohort studyCedric Daubin
Department of Medical Intensive Care, CHU de Caen, Caen, F 14000, France
BMC Cardiovasc Disord 11:48. 2011..The purpose of this study was to assess the capability of serum neuron-specific enolase (NSE), a biomarker of hypoxic brain damage, to predict death or vegetative state in comatose cardiac-arrest survivors...
A clinical and EEG scoring system that predicts early cortical response (N20) to somatosensory evoked potentials and outcome after cardiac arrestCedric Daubin
Department of Medical Intensive Care, Caen University Hospital, Caen, France
BMC Cardiovasc Disord 8:35. 2008..The aim of the current research was to construct a clinical and EEG scoring system that predicts early cortical response (N20) to somatosensory evoked potentials and 6-months outcome in comatose patients after cardiac arrest...
Effect of twice-daily nevirapine on adherence in HIV-1-infected patients: a randomized controlled studyJean Jacques Parienti
INSERM U707, Epidemiologie, Systemes d Informations, Modelisation, Paris, F 75012, France
AIDS 21:2217-22. 2007..For optimal adherence, once-daily dosing is best. Whether this applies to antiretroviral therapy is unknown. We thus aimed to determine the effect of once-daily dosing on adherence to nevirapine...
Femoral vs jugular venous catheterization and risk of nosocomial events in adults requiring acute renal replacement therapy: a randomized controlled trialJean Jacques Parienti
Department of Biostatistics and Clinical Research, Côte de Nacre University Hospital Center, Ave de la Côte de Nacre, 14033 Caen Cedex, France
JAMA 299:2413-22. 2008..Based on concerns about the risk of infection, the jugular site is often preferred over the femoral site for short-term dialysis vascular access...
Hospital-wide modification of fluoroquinolone policy and meticillin-resistant Staphylococcus aureus rates: a 10-year interrupted time-series analysisJ J Parienti
Department of Biostatistics and Clinical Research, CHU de Caen, Caen, France
J Hosp Infect 78:118-22. 2011..This study reinforces the rationale for a hospital-wide fluoroquinolone formulary policy to control MRSA and suggests that it has an additive effect with a hand hygiene promotion...
Cluster-crossover design: a method for limiting clusters level effect in community-intervention studiesJean Jacques Parienti
Department of Biostatistics and Clinical Research, Côte de Nacre University of Medicine, 14033 Caen, France
Contemp Clin Trials 28:316-23. 2007..Original data from two published field studies of hospital infection control based on this design are used here to illustrate the impact of different statistical models on the interpretation of the results...
Better adherence with once-daily antiretroviral regimens: a meta-analysisJean Jacques Parienti
Department of Biostatistics and Clinical Research, Cote de Nacre University Hospital, Caen, France
Clin Infect Dis 48:484-8. 2009..9%; 95% confidence interval, 1.0%-4.8%; P < .003) than with twice-daily regimens. This modest effect was more pronounced at the time of treatment initiation and for regimens for which all medications were taken once per day...
Catheter dysfunction and dialysis performance according to vascular access among 736 critically ill adults requiring renal replacement therapy: a randomized controlled studyJean Jacques Parienti
Department of Biostatistics and Clinical Research, Côte de Nacre University Hospital Center, Caen, France
Crit Care Med 38:1118-25. 2010..To compare dialysis catheter function according to catheter site...
[Nevirapine and cardiovascular risk]J J Parienti
Service des Maladies Infectieuses et Tropicales, CHU Cote de Nacre, Avenue de la Cote de Nacre, 14033 Caen, France
Med Mal Infect 40:499-505. 2010..This data should be considered when choosing antiretroviral treatment, especially for initiation of treatment in patients with cardiovascular risk factors or when substituting for an efficient tritherapy...
Continuous renal replacement therapy may increase the risk of catheter infectionJean Jacques Parienti
Biostatistics and Clinical Research, Cote de Nacre University Hospital, Caen, France
Clin J Am Soc Nephrol 5:1489-96. 2010..We compared the two modalities among critically ill adults requiring acute renal replacement therapy (RRT)...
Nevirapine once daily: pharmacology, metabolic profile and efficacy data of the new extended-release formulationJean Jacques Parienti
Department of Biostatistics and Clinical Research, Côte de Nacre Univ Hosp, Avenue de la Cote de Nacre, 14033 Caen, France
Expert Opin Drug Metab Toxicol 7:495-503. 2011..Further research is needed to predict short-term toxicity...
Efavirenz to nevirapine switch in HIV-1-infected patients with dyslipidemia: a randomized, controlled studyJean Jacques Parienti
Epidemiologie, Systemes d Informations, Modelisation, Institut National de la Sante et de la Recherche Medicale U707, Paris, France
Clin Infect Dis 45:263-6. 2007..04). A switch to nevirapine was associated with no severe adverse events...
Predictors of virologic failure and resistance in HIV-infected patients treated with nevirapine- or efavirenz-based antiretroviral therapyJean Jacques Parienti
Department of Infectious Diseases and Virology, Côte de Nacre Hospital, Caen, France
Clin Infect Dis 38:1311-6. 2004..8-180.3; P<.0001). Patients' previous adherence to therapy and drugs genetic barriers, not only the number of pills or doses involved, should be taken into consideration in the decision to simplify highly active antiretroviral therapy...
[Fluoroquinolone use and MRSA rates in hospitalized patients]P Charbonneau
, 14033 Caen Cedex, France
Med Mal Infect 35:S35-7. 2005
A randomized trial of two-drug versus three-drug tenofovir-containing maintenance regimens in virologically controlled HIV-1 patientsPierre Marie Girard
Service des Maladies Infectieuses et Tropicales, Hopital Saint Antoine, Assistance Publique Hopitaux de Paris, Universite Paris VI, Paris, France
J Antimicrob Chemother 64:126-34. 2009..To assess simplified maintenance regimens containing dual antiretroviral drugs in patients with controlled human immunodeficiency virus type 1 infection...
Cytokine therapy or structured treatment interruptions in HIV infection: which is best?Jean Jacques Parienti
Service de Maladies Infectieuses et Reanimation Medicale, Hôpital Côte de Nacre, Caen, France
Expert Opin Pharmacother 3:719-26. 2002..Ongoing and future clinical trials will provide a rationale for their use in clinical practice and will determine how these strategies can be combined to optimise HAART...
Nosocomial viral ventilator-associated pneumonia in the intensive care unit: a prospective cohort studyCedric Daubin
Department of Medical Intensive Care, Caen University Hospital, 14033, Caen Cedex, France
Intensive Care Med 31:1116-22. 2005..To determine the incidence, risk factors, and clinical relevance of viral ventilator-associated pneumonia (VAP) in an adult intensive care unit (ICU)...
Alcoholic povidone-iodine to prevent central venous catheter colonization: A randomized unit-crossover studyJean Jacques Parienti
Departments of Medical Intensive Care Unit, Cote de Nacre University Hospital, Caen, France
Crit Care Med 32:708-13. 2004..To compare effectiveness in preventing central venous catheter colonization and infection of two protocols of cutaneous antisepsis using povidone-iodine solution in combination with ethanol or water...
Vertebral osteomyelitis due to Bartonella henselae in adults: a report of 2 casesRenaud Verdon
Service de Maladies Infectieuses et Tropicales, Centre Hospitalier Universitaire Côte de Nacre, 14033 Caen Cedex, France
Clin Infect Dis 35:e141-4. 2002..Diagnosis was established on the basis of direct identification of the microorganism in one case and seroconversion in the other. Both patients recovered completely within 3 months...
Impact of anemia on outcome in critically ill patients with severe acute renal failureDamien du Cheyron
Department of Medical Intensive Care, Caen University Hospital, av Côte de Nacre, 14033, Caen Cedex, France
Intensive Care Med 31:1529-36. 2005..To evaluate the prognostic value of hemoglobin levels in critically ill patients with acute renal failure (ARF) requiring dialysis...
The attributable mortality of acute renal failure in critically ill patients with liver cirrhosisDamien du Cheyron
Department of Medical Intensive Care, Caen University Hospital, av Côte de Nacre, 14033, Caen Cedex, France
Intensive Care Med 31:1693-9. 2005..To determine outcome and mortality risk related to acute renal failure (ARF) in critically ill patients with cirrhosis...
Fluoroquinolone use and methicillin-resistant Staphylococcus aureus isolation rates in hospitalized patients: a quasi experimental studyPierre Charbonneau
Department of Medical Intensive Care Unit, Cote de Nacre University Hospital, Caen, France
Clin Infect Dis 42:778-84. 2006..We investigated the possible association between fluoroquinolone use and the rate of methicillin-resistant Staphylococcus aureus (MRSA) recovery from consecutive hospitalized patients...
An information campaign on aminoglycosides use during septic shock failed to improve the quality of careM O Fischer
Pôle anesthésie réanimation Samu Smur coordination hospitalière hémovigilance, CHU de Caen, France
Ann Fr Anesth Reanim 31:e1-5. 2012..The aim of the study was to assess the impact of an information campaign on modalities of prescription of aminoglycosides in septic shock...
Switching the nucleoside reverse transcriptase inhibitor backbone to tenofovir disoproxil fumarate + emtricitabine promptly improves triglycerides and low-density lipoprotein cholesterol in dyslipidaemic patientsM A Valantin
Department of Infectious Diseases, AP HP, Pitie Salpetriere Hospital, Paris, France
J Antimicrob Chemother 65:556-61. 2010..To assess the impact of switching to tenofovir disoproxil fumarate + emtricitabine on lipid parameters...
Oral thromboprophylaxis following total hip replacement: the issue of complianceB Lebel
Caen University Hospital Center, Orthopedics Department, Avenue de la Cote de Nacre, 14000 Caen, France
Orthop Traumatol Surg Res 98:186-92. 2012....
[Epidemiology of candidemia: a one-year prospective observational study in the west of France]J P Talarmin
Service des Maladies Infectieuses et Tropicales, CHU Hotel Dieu, Nantes Cedex 1, France
Med Mal Infect 39:877-85. 2009..A one-year prospective, observational study was conducted in the west of France, to evaluate the epidemiology of candidemia...
Intravenous drug users risk group should also benefit from simpler highly active antiretroviral therapyJean-Jacques Parienti
AIDS 16:2097; author reply 2098. 2002
Predictors of virological rebound in the APROCO cohort studyJean-Jacques Parienti
AIDS 16:2369. 2002
Knowledge of and adherence to antiretroviral therapyJean-Jacques Parienti
Clin Infect Dis 37:861-2; author reply 862-3. 2003
Tenofovir, equivalence, and noninferiorityJean-Jacques Parienti
JAMA 292:1951; author reply 1951-2. 2004
Quality of care and satisfaction among patients isolated for infection controlJean-Jacques Parienti
JAMA 291:420; author reply 421-2. 2004
Perioperative use of dobutamine in cardiac surgery and adverse cardiac outcome: propensity-adjusted analysesJean Luc Fellahi
Centre Hospitalier Privé Saint Martin, Caen Université Pierre et Marie Curie Paris 6, EA3975, Paris
Anesthesiology 108:979-87. 2008..The current study assessed the consequences on clinical outcome of catecholamines simply based on the clinical judgment of the anesthesiologists after cardiopulmonary bypass in adult cardiac surgery...
Viral pneumonia and respiratory sepsis: association, causation, or it depends?Jean Jacques Parienti
Crit Care Med 35:639-40. 2007
Treatment resistance after sequential interruption of a non-nucleoside reverse transcriptase inhibitor-based regimenSylvie Dargere
AIDS 21:879-80. 2007
