M Paccalin

Summary

Affiliation: CHU de Poitiers
Country: France

Publications

  1. pmc The validation of a French-language version of the Aging Perceptions Questionnaire (APQ) and its extension to a population aged 55 and over
    Isabelle Ingrand
    Pôle Biologie, Pharmacie et Santé Publique, Centre Hospitalier Universitaire de Poitiers, Universite de Poitiers, Poitiers, France
    BMC Geriatr 12:17. 2012
  2. pmc Prevention of the β-amyloid peptide-induced inflammatory process by inhibition of double-stranded RNA-dependent protein kinase in primary murine mixed co-cultures
    J Couturier
    Research Group on Brain Aging, GReViC EA 3808, 6 rue de la Milétrie BP 199, 86034 Poitiers Cedex, France
    J Neuroinflammation 8:72. 2011
  3. ncbi request reprint [Adequacy between prescriptions and CHADS(2) score recommendations in geriatric patients]
    Nolya Haïda
    Département de gériatrie Pôle médecine
    Geriatr Psychol Neuropsychiatr Vieil 9:39-44. 2011
  4. ncbi request reprint Peripheral p70S6k levels and emotional memory in patients with Alzheimer's disease
    Marc Paccalin
    Research Group on Brain Aging EA3808, University of Poitiers, Poitiers University Hospital, France
    Neurosci Lett 410:162-4. 2006
  5. ncbi request reprint Lack of correlation between nutritional status and seroprotection against influenza in a long term care facility
    Marc Paccalin
    Geriatrics Department, University Hospital of Poitiers, 86021 Poitiers Cedex, France
    Scand J Infect Dis 38:894-7. 2006
  6. ncbi request reprint Activated mTOR and PKR kinases in lymphocytes correlate with memory and cognitive decline in Alzheimer's disease
    Marc Paccalin
    Brain Aging Research Group EA 3808, University of Poitiers, Poitiers, France
    Dement Geriatr Cogn Disord 22:320-6. 2006
  7. ncbi request reprint Antiphospholipid syndrome in patients with retinal venous occlusion
    M Paccalin
    Department of Internal Medicine, University Hospital La Miletrie, Poitiers, France
    Thromb Res 117:365-9. 2006
  8. ncbi request reprint [Automobile driving among patients with dementia. Survey in the Poitou-Charentes region]
    Marc Paccalin
    Departement de Geriatrie, CHU La Miletrie, Poitiers
    Presse Med 34:919-22. 2005
  9. ncbi request reprint [Primary thyroid lymphoma: report of 8 cases]
    M Paccalin
    Service de médecine interne endocrinologie, CHU La Miletrie, rue de la Miletrie, 86021 Poitiers, France
    Rev Med Interne 22:934-8. 2001
  10. ncbi request reprint [A diagnosis paved with good intentions!]
    M Paccalin
    Service de Medecine Interne, CHU La Miletrie, 86021 Poitiers Cedex, France
    Rev Med Interne 25:S261-2. 2004

Collaborators

Detail Information

Publications32

  1. pmc The validation of a French-language version of the Aging Perceptions Questionnaire (APQ) and its extension to a population aged 55 and over
    Isabelle Ingrand
    Pôle Biologie, Pharmacie et Santé Publique, Centre Hospitalier Universitaire de Poitiers, Universite de Poitiers, Poitiers, France
    BMC Geriatr 12:17. 2012
    ..The secondary objective was to study the stability of the dimensions of this instrument among participants aged 55 to 64...
  2. pmc Prevention of the β-amyloid peptide-induced inflammatory process by inhibition of double-stranded RNA-dependent protein kinase in primary murine mixed co-cultures
    J Couturier
    Research Group on Brain Aging, GReViC EA 3808, 6 rue de la Milétrie BP 199, 86034 Poitiers Cedex, France
    J Neuroinflammation 8:72. 2011
    ..This led us to study the effect of a specific inhibitor of PKR on the Aβ42-induced inflammatory response in primary mixed murine co-cultures, allowing interactions between neurons, astrocytes and microglia...
  3. ncbi request reprint [Adequacy between prescriptions and CHADS(2) score recommendations in geriatric patients]
    Nolya Haïda
    Département de gériatrie Pôle médecine
    Geriatr Psychol Neuropsychiatr Vieil 9:39-44. 2011
    ..But such therapy remains underused particularly among elderly patients. The aim of our study was to evaluate the adequacy between prescriptions and CHADS(2) recommendations in geriatric hospitalised patients with AF...
  4. ncbi request reprint Peripheral p70S6k levels and emotional memory in patients with Alzheimer's disease
    Marc Paccalin
    Research Group on Brain Aging EA3808, University of Poitiers, Poitiers University Hospital, France
    Neurosci Lett 410:162-4. 2006
    ..The decline of emotional memory in AD patients is reflected by the decrease of p70S6k levels...
  5. ncbi request reprint Lack of correlation between nutritional status and seroprotection against influenza in a long term care facility
    Marc Paccalin
    Geriatrics Department, University Hospital of Poitiers, 86021 Poitiers Cedex, France
    Scand J Infect Dis 38:894-7. 2006
    ..Virologic diagnosis was assessed using viral isolation, polymerase chain reaction and serology for all patients with a flu-like syndrome. Albumin, vitamins and trace elements were also measured...
  6. ncbi request reprint Activated mTOR and PKR kinases in lymphocytes correlate with memory and cognitive decline in Alzheimer's disease
    Marc Paccalin
    Brain Aging Research Group EA 3808, University of Poitiers, Poitiers, France
    Dement Geriatr Cogn Disord 22:320-6. 2006
    ..In AD increased susceptibility of lymphocytes to apoptosis has been reported...
  7. ncbi request reprint Antiphospholipid syndrome in patients with retinal venous occlusion
    M Paccalin
    Department of Internal Medicine, University Hospital La Miletrie, Poitiers, France
    Thromb Res 117:365-9. 2006
    ..We conducted a prospective study to determine the prevalence and the prognosis of antiphospholipid syndrome (APS) in patients with retinal venous occlusion (RVO)...
  8. ncbi request reprint [Automobile driving among patients with dementia. Survey in the Poitou-Charentes region]
    Marc Paccalin
    Departement de Geriatrie, CHU La Miletrie, Poitiers
    Presse Med 34:919-22. 2005
    ..To determine the characteristics of drivers with dementia and analyze their driving habits...
  9. ncbi request reprint [Primary thyroid lymphoma: report of 8 cases]
    M Paccalin
    Service de médecine interne endocrinologie, CHU La Miletrie, rue de la Miletrie, 86021 Poitiers, France
    Rev Med Interne 22:934-8. 2001
    ..Primary thyroid lymphoma (PTL) is a rare disease. Few patients are reported in the literature. We report eight new cases of PTL with long-term follow-up...
  10. ncbi request reprint [A diagnosis paved with good intentions!]
    M Paccalin
    Service de Medecine Interne, CHU La Miletrie, 86021 Poitiers Cedex, France
    Rev Med Interne 25:S261-2. 2004
  11. ncbi request reprint Central venous catheter-related infection due to Comamonas testosteroni in a woman with breast cancer
    G Le Moal
    Department of Internal Medicine and Infectious Diseases, , Poitiers, France
    Scand J Infect Dis 33:627-8. 2001
    ..This germ seems to be a rare pathogen; as reported in the literature, it is mostly encountered in patients with predisposing factors...
  12. ncbi request reprint [Late diagnosis of Dandy-Walker syndrome revealed by gait disorders in an elderly]
    D Forestier
    Pôle de gériatrie, Hopital La Miletrie, Centre Hospitalier Universitaire de Poitiers, 2, rue de la Miletrie, 86021 Poitiers, France
    Rev Med Interne 29:421-3. 2008
    ..We report a case in an elderly hospitalised for gait disorders and recurrent falls. Cerebral MRI revealed hydrocephalus and posterior fossa cyst. The patient improved after ventriculocisternostomia...
  13. ncbi request reprint Usefulness of the short IQCODE for predicting postoperative delirium in elderly patients undergoing hip and knee replacement surgery
    Mathieu Priner
    Departement de Geriatrie, Centre Hospitalier Universitaire de Poitiers, Poitiers, France
    Gerontology 54:116-9. 2008
    ....
  14. ncbi request reprint Effects of a physical training programme on cognitive function and walking efficiency in elderly persons with dementia
    Gilles Kemoun
    Department of Physical Medicine and Rehabilitation, University Hospital of Poitiers, Poitiers, France
    Dement Geriatr Cogn Disord 29:109-14. 2010
    ..To study the effects of physical stimulation based on walking exercises, equilibrium and endurance on cognitive function and walking efficiency in patients with dementia...
  15. ncbi request reprint A case of emphysematous cystitis
    David Forestier
    Departement de Geriatrie, CHU La Miletrie, Poitiers, France
    Gerontology 50:259. 2004
  16. doi request reprint [Vaccine coverage against influenza and pneumococcal infections in patients aged 65 and over: a survey on 299 outpatients]
    A S Delelis-Fanien
    Pôle de gériatrie, CHU La Miletrie, 2, rue de la Miletrie, 86021 Poitiers Cedex, France
    Rev Med Interne 30:656-60. 2009
    ..There is no compulsory vaccination in the adult population. Therefore, vaccine coverage appears heterogeneous...
  17. ncbi request reprint [Pelvic embryonal tumor]
    C Landron
    Service de Medecine Interne, Hopital La Miletrie, Centre Hospitalier Universitaire, rue de la Miletrie, BP 577, 86021 Poitiers Cedex, France
    Rev Med Interne 24:266-7. 2003
  18. ncbi request reprint Clinical and laboratory characteristics of infective endocarditis when associated with spondylodiscitis
    G Le Moal
    Department of Internal Medicine and Infectious Diseases, CHU La Miletrie, Avenue J Coeur, 86021 Poitiers Cedex, France
    Eur J Clin Microbiol Infect Dis 21:671-5. 2002
    ..IE should be included in the differential diagnosis in patients with infectious spondylodiscitis and risk factors for endocarditis. In such patients, echocardiography should be performed routinely...
  19. doi request reprint PKR, a cognitive decline biomarker, can regulate translation via two consecutive molecular targets p53 and Redd1 in lymphocytes of AD patients
    Milena Damjanac
    Research Group on Brain Aging EA 3808, University of Poitiers, Poitiers, Cedex, France
    J Cell Mol Med 13:1823-32. 2009
    ..PKR represents a cognitive decline biomarker able to dysregulate translation via two consecutive targets p53 and Redd1 in AD lymphocytes...
  20. ncbi request reprint mTOR/p70S6k signalling alteration by Abeta exposure as well as in APP-PS1 transgenic models and in patients with Alzheimer's disease
    Claire Lafay-Chebassier
    Department of Pharmacology, Poitiers University Hospital, France
    J Neurochem 94:215-25. 2005
    ....
  21. ncbi request reprint [Diagnosis and epidemiological surveillance of influenza and respiratory syncytial virus infections: interest of multiplex PCR]
    C Plouzeau
    Laboratoire de Virologie, CHU de Poitiers, 2, rue de la Miletrie, BP 577, 86021 Poitiers Cedex, France
    Med Mal Infect 37:728-33. 2007
    ..We evaluated multiplex PCR used for the diagnosis and the epidemiological surveillance of influenza and respiratory syncytial virus (RSV) infections...
  22. ncbi request reprint [Do not take lanterns for bladders!]
    P Roblot
    Service de Medecine Interne et Maladies Infectieuses, CHU La Miletrie, 86021 Poitiers Cedex, France
    Rev Med Interne 25:S285. 2004
  23. ncbi request reprint [I love you, but not anymore...]
    C Landron
    Service de Medecine Interne, CHU La Miletrie, Poitiers, France
    Rev Med Interne 26:S203-5. 2005
  24. pmc Interaction of double-stranded RNA-dependent protein kinase (PKR) with the death receptor signaling pathway in amyloid beta (Abeta)-treated cells and in APPSLPS1 knock-in mice
    Julien Couturier
    Research Group on Brain Aging, GReViC EA 3808, University of Poitiers, 6 rue de la Miletrie, BP 199, 86034 Poitiers Cedex, France
    J Biol Chem 285:1272-82. 2010
    ..The contribution of PKR in neurodegeneration through the death receptor signaling pathway may support the development of therapeutics targeting PKR to limit neuronal death in AD...
  25. doi request reprint Evidence of molecular links between PKR and mTOR signalling pathways in Abeta neurotoxicity: role of p53, Redd1 and TSC2
    Milena Morel
    Research Group on Brain Aging, GReViC EA 3808, University of Poitiers, 6 rue de la Milétrie BP 199, 86034 Poitiers Cedex, France
    Neurobiol Dis 36:151-61. 2009
    ..The PKR gene silencing in SH-SY5Y cells prevented these alterations. p53, Redd1 and TSC2 could represent the molecular links between PKR and mTOR in Abeta neurotoxicity. PKR could be a critical target in a therapeutic program of AD...
  26. ncbi request reprint [Treatment of high-grade, disseminated non-Hodgkin's lymphoma in elderly patients]
    M Paccalin
    Service de Medecine Interne, CHU La Miletrie, rue de la Miletrie, 86021 Poitiers, France
    Rev Med Interne 23:632-7. 2002
    ..Potential interest of chemotherapy and associated immunotherapy is on study. Without any influence on survival duration, haematopoietic growth factors seem to improve the tolerance of the treatment...
  27. doi request reprint Images in gerontology: a case report
    R Coudroy
    Pôle de gériatrie, CHU La Miletrie, Poitiers, France
    Gerontology 56:39-40. 2010
    ..Left ventricular aneurysm can complicate acute myocardial infarction. Clinical and electrocardiogram features are not specific. We describe a case with asymptomatic left ventricular aneurysm diagnosed by computerized-tomography angiography...
  28. ncbi request reprint Cat-scratch disease simulating a malignant process of the chest wall
    F Millot
    Service d Hématologie et Oncologie Médicale, CHU Jean Bernard, La Miletrie, Poitiers, France
    Eur J Pediatr 158:403-5. 1999
    ..Serological investigations were positive for Bartonella species. The symptoms and the lesions disappeared after oral antibiotic therapy (ciprofloxacin) was started. The patient remained symptom-free 12 months later...
  29. ncbi request reprint Localized amyloidosis: a survey of 35 French cases
    Marc Paccalin
    Department of Internal Medicine, Hopital Jean Bernard, BP 577, 86021, Poitiers Cedex, France
    Amyloid 12:239-45. 2005
    ..Such patients should be referred to specialist centers for further evaluation. Management requires close follow-up to exclude recurrence and to determine the appropriate symptomatic treatment...
  30. ncbi request reprint The relation between p70S6k expression in lymphocytes and the decline of cognitive test scores in patients with Alzheimer disease
    Marc Paccalin
    Arch Intern Med 165:2428-9. 2005
  31. ncbi request reprint Acute tubular necrosis due to rhabdomyolysis resulting from influenza A infection
    Christine Pradère
    J Am Geriatr Soc 54:725. 2006
  32. ncbi request reprint Dissociation of Akt/PKB and ribosomal S6 kinase signaling markers in a transgenic mouse model of Alzheimer's disease
    Milena Damjanac
    Research Group on Brain Aging EA 3808 University of Poitiers, 6 rue de la Milétrie BP 199, 86034 Poitiers, Cedex, France
    Neurobiol Dis 29:354-67. 2008
    ..These findings demonstrate a clear dissociation between Akt and ribosomal S6K signaling markers in these mice which could be involved in the AD pathological process...