Pierre Michel Llorca

Summary

Affiliation: CHU de Clermont-Ferrand
Country: France

Publications

  1. ncbi request reprint Discussion of prevalence and management of discomfort when swallowing pills: orodispersible tablets expand treatment options in patients with depression
    Pierre Michel Llorca
    Centre Medico Psychologique B, Centre Hospitalier Universitaire, BP 69, 63003, Clermont Ferrand, Cedex I, France
    Ther Deliv 2:611-22. 2011
  2. doi request reprint [Subjective feeling of patient on his illness and his treatment]
    P M Llorca
    CHU Clermont Ferrand, Universite d Auvergne, EA 7230 Electronic address
    Encephale 39:S99-104. 2013
  3. doi request reprint [Current status and management of patients with bipolar disorder in France: the MONTRA survey]
    P M Llorca
    Service de Psychiatrie B, CHU de Clermont Ferrand, 58, rue Montalembert, 63000 Clermont Ferrand, France
    Encephale 39:212-23. 2013
  4. doi request reprint [Mixed states]
    Pierre Michel Llorca
    CHU Clermont Ferrand, BP 69, Clermont Ferrand cedex 01, France
    Encephale 38:S179-85. 2012
  5. doi request reprint [Second generation antipsychotics in bipolar depression: a new therapeutic option?]
    P M Llorca
    CHU Clermont Ferrand, BP 69, Clermont Ferrand cedex 01, France
    Encephale 37:S209-13. 2011
  6. doi request reprint The antidepressant agomelatine improves the quality of life of depressed patients: implications for remission
    Pierre Michel Llorca
    CHU Clermont Ferrand, Université d Auvergne EA 3845, CMP B, 63003 Clermont Ferrand Cedex 1, France
    J Psychopharmacol 24:21-6. 2010
  7. doi request reprint Monitoring patients to improve physical health and treatment outcome
    Pierre Michel Llorca
    Centre Medico Psychologique B, Centre Hospitalier Universitaire, Clermont Ferrand Cedex 1, France
    Eur Neuropsychopharmacol 18:S140-5. 2008
  8. ncbi request reprint Escitalopram in the treatment of major depressive disorder: clinical efficacy, tolerability and cost-effectiveness vs. venlafaxine extended-release formulation
    P M Llorca
    Service de Psychiatrie, Centre Hospitalier Universitaire, Clermont Ferrand, France
    Int J Clin Pract 61:702-10. 2007
  9. doi request reprint Improved symptom control, functioning and satisfaction in French patients treated with long-acting injectable risperidone
    P M Llorca
    Centre Hospitalier Universitaire, Psychiatrie B, Place Henri Dunand, 63003 Clermont Ferrand Cedex 1, France
    Encephale 34:170-8. 2008
  10. doi request reprint [Severe depression : the doctor/patient relationship]
    P M Llorca
    CMP B, CHU Clermont Ferrand, Universite d Auvergne
    Encephale 35:S310-3. 2009

Detail Information

Publications58

  1. ncbi request reprint Discussion of prevalence and management of discomfort when swallowing pills: orodispersible tablets expand treatment options in patients with depression
    Pierre Michel Llorca
    Centre Medico Psychologique B, Centre Hospitalier Universitaire, BP 69, 63003, Clermont Ferrand, Cedex I, France
    Ther Deliv 2:611-22. 2011
    ..Orodispersible tablets do not need to be taken with water and can be packaged discreetly in single doses. Orodispersible tablets have been shown to be effective in a number of therapy areas including depression...
  2. doi request reprint [Subjective feeling of patient on his illness and his treatment]
    P M Llorca
    CHU Clermont Ferrand, Universite d Auvergne, EA 7230 Electronic address
    Encephale 39:S99-104. 2013
    ..Identification of these subjective dimensions is needed to develop more efficacious strategies. ..
  3. doi request reprint [Current status and management of patients with bipolar disorder in France: the MONTRA survey]
    P M Llorca
    Service de Psychiatrie B, CHU de Clermont Ferrand, 58, rue Montalembert, 63000 Clermont Ferrand, France
    Encephale 39:212-23. 2013
    ..The objectives were to assess the characteristics of patients with bipolar disorder (BD) and to evaluate the prescribing practices...
  4. doi request reprint [Mixed states]
    Pierre Michel Llorca
    CHU Clermont Ferrand, BP 69, Clermont Ferrand cedex 01, France
    Encephale 38:S179-85. 2012
    ..As the evolution, the prognosis or the therapeutic strategies differ from what is applied in other thymic episodes, this transition from "mixed state" to manic or depressive episodes "with mixed features" may be relevant in practice...
  5. doi request reprint [Second generation antipsychotics in bipolar depression: a new therapeutic option?]
    P M Llorca
    CHU Clermont Ferrand, BP 69, Clermont Ferrand cedex 01, France
    Encephale 37:S209-13. 2011
    ..Second generation antipsychotics may prove to be important future treatments for patients with bipolar depression...
  6. doi request reprint The antidepressant agomelatine improves the quality of life of depressed patients: implications for remission
    Pierre Michel Llorca
    CHU Clermont Ferrand, Université d Auvergne EA 3845, CMP B, 63003 Clermont Ferrand Cedex 1, France
    J Psychopharmacol 24:21-6. 2010
    ....
  7. doi request reprint Monitoring patients to improve physical health and treatment outcome
    Pierre Michel Llorca
    Centre Medico Psychologique B, Centre Hospitalier Universitaire, Clermont Ferrand Cedex 1, France
    Eur Neuropsychopharmacol 18:S140-5. 2008
    ..Good clinical practice suggests that investment in patient monitoring is offset by improved clinical outcomes...
  8. ncbi request reprint Escitalopram in the treatment of major depressive disorder: clinical efficacy, tolerability and cost-effectiveness vs. venlafaxine extended-release formulation
    P M Llorca
    Service de Psychiatrie, Centre Hospitalier Universitaire, Clermont Ferrand, France
    Int J Clin Pract 61:702-10. 2007
    ..Based on this evidence, it is concluded that escitalopram is at least as effective as venlafaxine XR in the treatment of MDD, but is better tolerated and may also have cost advantages...
  9. doi request reprint Improved symptom control, functioning and satisfaction in French patients treated with long-acting injectable risperidone
    P M Llorca
    Centre Hospitalier Universitaire, Psychiatrie B, Place Henri Dunand, 63003 Clermont Ferrand Cedex 1, France
    Encephale 34:170-8. 2008
    ..To investigate the efficacy and tolerability of direct initiation of long-acting injectable risperidone (LAIR) in adults with schizophrenia or other psychotic disorders requiring a change of treatment...
  10. doi request reprint [Severe depression : the doctor/patient relationship]
    P M Llorca
    CMP B, CHU Clermont Ferrand, Universite d Auvergne
    Encephale 35:S310-3. 2009
    ..One of the goals clinicians may have, is to achieve shared understanding between patient and themselves about the patient's problems and their treatment...
  11. doi request reprint [Prevention in schizophrenia]
    Pierre Michel Llorca
    CMP B CHU, Clermont Ferrand, France
    Therapie 63:251-5. 2008
    ..By now, prevention strategies have to be improved in the filed of schizophrenia, and make the proof of ther interest beyond the research perspectives...
  12. pmc Effectiveness of clozapine in neuroleptic-resistant schizophrenia: clinical response and plasma concentrations
    Pierre Michel Llorca
    Centre Medico Psychologique B, Centre Hospitalier Universitaire, BP 69, 63003 Clermont Ferrand, France
    J Psychiatry Neurosci 27:30-7. 2002
    ....
  13. doi request reprint Partial compliance in schizophrenia and the impact on patient outcomes
    Pierre Michel Llorca
    Centre Medico Psychologique B, Centre Hospitalier Universitaire, Clermont Ferrand, France
    Psychiatry Res 161:235-47. 2008
    ..Long-acting risperidone may therefore bring together the benefits of the atypical antipsychotics with the long-acting injection delivery system required to build a platform for improved outcomes...
  14. doi request reprint [What is the contribution of clinical practice recommendations concerning the prevention of depressive recurrences?]
    P M Llorca
    Service de Psychiatrie B, CHU Clermont Ferrand, Hopital Gabriel Montpied, Clermont Ferrand, France
    Encephale 36:S150-4. 2010
    ..But, a large proportion of people with a depressive disorder do not receive minimally adequate treatment. Improving the concordance of everyday practice with clinical recommendations should be an important goal for clinicians...
  15. doi request reprint [The contributions of the evidence-based medicine or how to optimize the management of major depressive disorder]
    P M Llorca
    CMP B, Universite d Auvergne, CHU de Clermont Ferrand, France
    Encephale 37:457-65. 2011
    ..It may be insufficiently known and understood, seems too complex, time-consuming and therefore inapplicable. We have to mobilize our efforts to improve our practices...
  16. ncbi request reprint The use of biological laboratory markers in the diagnosis of alcohol misuse: an evidence-based approach
    Raymund Schwan
    Department of Psychiatry, University Medical School, Clermont Ferrand, France
    Drug Alcohol Depend 74:273-9. 2004
    ..Our aim was to determine how best to use biological markers to objectify alcohol problems in patients with clinical suspicion of alcohol misuse...
  17. doi request reprint Methodological differences between pharmacological treatment guidelines for bipolar disorder: what to do for the clinicians?
    Ludovic Samalin
    Department of Adult Psychiatry B, CHU Clermont Ferrand, 58 rue Montalembert, 63000 Clermont Ferrand, France
    Compr Psychiatry 54:309-20. 2013
    ..The aim of this article is to underline the main differences between consensus-based guidelines (CBG) and evidence-based guidelines (EBG) currently available for the management of bipolar disorder...
  18. doi request reprint Clinical predictors of response to olanzapine or risperidone during acute episode of schizophrenia
    Georges Brousse
    University Clermont 1, UFR Medecine, EA 3845, CHU Clermont Ferrand, Service de Psychiatrie B, Clermont Ferrand, F63001, France
    Psychiatry Res 179:12-8. 2010
    ..Clinical variables do not clearly appear to be good predictors of treatment efficacy...
  19. doi request reprint Is pregnancy the time to change alcohol consumption habits in France?
    Ingrid de Chazeron
    CHU Clermont Ferrand, Psychiatry B, Clermont Ferrand Cedex, France
    Alcohol Clin Exp Res 32:868-73. 2008
    ..Although it is well known that France has a cultural history of alcohol use, no recent French data on alcohol consumption during pregnancy in a large sample are available...
  20. doi request reprint Prevalence and phenomenology of olfactory hallucinations in Parkinson's disease
    Stephanie Bannier
    CHU Clermont Ferrand, Neurology Department, Clermont Ferrand, France
    J Neurol Neurosurg Psychiatry 83:1019-21. 2012
    ..Although visual hallucinations in Parkinson's disease (PD) have been described in several major studies, little is known about olfactory hallucinations (OHs)...
  21. ncbi request reprint Tardive dyskinesias and antipsychotics: a review
    Pierre Michel Llorca
    C M P B, C H U Clermont Ferrand, rue Montalembert, BP 69, 63003 cedex 1, Clermont Ferrand, France
    Eur Psychiatry 17:129-38. 2002
    ..They are doubtlessly promising, but we cannot ignore the notion of risk-benefit; regular monitoring and listening to the subjective experience of the patients must remain uppermost in the choice of therapy...
  22. doi request reprint Hypersexuality and pathological gambling in Parkinson's disease: A cross-sectional case-control study
    Ingrid de Chazeron
    Univ Clermont 1, UFR Medecine, Clermont Ferrand, France
    Mov Disord 26:2127-30. 2011
    ....
  23. ncbi request reprint General practitioners and alcohol use disorders: quantity without quality
    Laurent Malet
    Department of Psychiatry, Centre Hospitalier Universitaire, Clermont Ferrand, France
    Alcohol Clin Exp Res 27:61-6. 2003
    ..General medical practitioners are essential for the prevention, diagnosis, and management of alcohol use disorders. Studies to examine medical practice in this field, however, are very rare...
  24. ncbi request reprint [Disulfiram and addiction: reminders and new perspectives of use]
    Thomas Charpeaud
    Service de Psychiatrie de l Adulte B, CHU de Clermont Ferrand, Clermont Ferrand, France
    Therapie 66:273-80. 2011
    ..Although current data are insufficient to generalize its use in routine practice, they constitute a line of research interest for the future...
  25. doi request reprint Body weight gain and deep brain stimulation
    Isabelle Rieu
    CHU Clermont Ferrand, Neurology Department, Clermont Ferrand, F 63001, France
    J Neurol Sci 310:267-70. 2011
    ..This review reports current knowledge concerning weight changes in patients treated by DBS with different surgical targets. It also describes the mechanisms responsible for weight gain and the health outcome for the patients...
  26. doi request reprint Validity study of Kessler's psychological distress scales conducted among patients admitted to French emergency department for alcohol consumption-related disorders
    Benjamin Arnaud
    CHU Clermont Ferrand, Unité Urgences Psychiatriques, France
    Alcohol Clin Exp Res 34:1235-45. 2010
    ..Kessler's K6/10 psychological distress scales are fast, easy-to-use, and have been shown to achieve a good performance in the identification of psychological distress associated with ARD...
  27. doi request reprint Outcomes from primary care management of alcohol dependence in France
    Laurent Malet
    CHU Clermont Ferrand, Psychiatrie B, 57 rue Montalembert, Clermont Ferrand 63000, France
    J Subst Abuse Treat 36:457-62. 2009
    ....
  28. ncbi request reprint AlQoL 9 for measuring quality of life in alcohol dependence
    Laurent Malet
    Centre Hospitalier Universitaire, Department of Psychiatry B, Rue Montalembert BP 69, 63003 Clermont Ferrand Cedex 1, France
    Alcohol Alcohol 41:181-7. 2006
    ..A 9-item QoL scale, AlQoL 9, obtained from the generic SF 36, is proposed as a measure that characterizes the QoL of alcohol-dependent patients. Our objective was to study the psychometric properties of this subscale...
  29. ncbi request reprint Alcohol consumption during pregnancy: a urge to increase prevention and screening
    Laurent Malet
    Psychiatrie B, CHU Clermont Ferrand, Rue Montalembert BP 69, F 63000, Clermont Ferrand, France
    Eur J Epidemiol 21:787-8. 2006
    ..One percent had 5 or more units per occasion. Despite the consensus recommending total abstinence during pregnancy, prenatal alcohol exposure remains a major public health issue...
  30. ncbi request reprint Multicenter validation study of the %CDT TIA kit in alcohol abuse and alcohol dependence
    Raymund Schwan
    Department of Psychiatry, University Hospital, Clermont Ferrand, France
    Alcohol Clin Exp Res 28:1331-7. 2004
    ..The aim of this study was to evaluate, in terms of sensitivity and specificity, the performance of the new Bio-Rad %CDT TIA kit and GGT assay for identifying alcohol abuse and alcohol dependence (according to the DSM-IV criteria)...
  31. doi request reprint Clinicians' attitudes toward the use of long-acting injectable antipsychotics
    Ludovic Samalin
    Department of Psychiatry B, University of Auvergne, Clermont Ferrand, France
    J Nerv Ment Dis 201:553-9. 2013
    ..Conversely, some attitudes related to organizational aspects, particularly the relevance of health care costs, may vary from one country to another. ..
  32. ncbi request reprint Limits of usual biochemical alcohol markers in cord blood at term: a fetal/maternal population-based study
    Denis Gallot
    Universite d Auvergne, JE2447, ARDEMO, and CHU, maternité Hôtel Dieu, Clermont Ferrand, France
    Clin Chem Lab Med 45:546-8. 2007
    ..The aim of our study was to assess the efficiency of the usual alcohol biomarkers measured in cord blood to identify alcohol-exposed neonates immediately after birth...
  33. doi request reprint Bilateral lesions of the nigrostriatal pathways are associated with chronic mechanical pain hypersensitivity in rats
    Yildiz Zengin-Toktas
    Clermont Universite, Universite d Auvergne, EA 7280, BP 38, F 63001 Clermont Ferrand, France
    Neurosci Res 76:261-4. 2013
    ..This animal model displays nociceptive disorders as found in PD patients and could be useful to assess the effects of new antiparkinsonian drugs. ..
  34. doi request reprint A composite scale applied to evaluate anxiety in schizophrenic patients (SAES)
    Pierre Michel Llorca
    CHU of Clermont Ferrand, Psychiatry Service, Place Henri Dunant, 63000, Clermont Ferrand, France
    Eur Arch Psychiatry Clin Neurosci 264:171-8. 2014
    ..The SAES can be useful to investigate clinical, psychopathological, and therapeutic aspects of anxiety in schizophrenia. ..
  35. doi request reprint Guidelines for the use and management of long-acting injectable antipsychotics in serious mental illness
    Pierre Michel Llorca
    CHU Clermont Ferrand, EA 7280, Clermont Ferrand University, Clermont Ferrand, France
    BMC Psychiatry 13:340. 2013
    ..As part of a process to improve the quality of care, the French Association for Biological Psychiatry and Neuropsychopharmacology (AFPBN) elaborated guidelines for the use and management of antipsychotic depots in clinical practice...
  36. doi request reprint Contact dependent reproducible hypomania induced by deep brain stimulation in Parkinson's disease: clinical, anatomical and functional imaging study
    Miguel Ulla
    Service de Neurologie A, Hopital Gabriel Montpied, 58 rue Montalembert, CHU Clermont Ferrand, F 63000 Clermont Ferrand, France
    J Neurol Neurosurg Psychiatry 82:607-14. 2011
    ..The present study demonstrates the role of the subcortical structures in the genesis of hypomania in PD patients treated with DBS and stresses the involvement of the substantia nigra...
  37. ncbi request reprint Validity of the CAGE questionnaire in hospital
    Laurent Malet
    Centre Hospitalier Universitaire, Department of Psychiatry B, Rue Montalembert BP 69, 63003 Clermont Ferrand Cedex 1, France
    Eur Psychiatry 20:484-9. 2005
    ..Our objectives were to validate the French version of the CAGE against DSM-IV criteria and to assess performance of each item of the scale...
  38. ncbi request reprint [Systematic use in hospitals of a alcohol problems detecting questionnaire. The CAGE (cut down, annoyed, guilty, eye opener) questionnaire]
    Laurent Malet
    Centre Hospitalier Universitaire, CMP B, Clermont Ferrand
    Presse Med 34:502-5. 2005
    ..Its sensitivity exceeds 75% and its specificity 90%. Our objective was to assess performance of the French version of the CAGE (DETA) in identifying patients who meet the DSM-IV criteria and to discuss its usefulness in hospitals...
  39. doi request reprint Pharmacogenetic of response efficacy to antipsychotics in schizophrenia: pharmacodynamic aspects. Review and implications for clinical research
    Olivier Blanc
    Univ Clermont, UFR Medecine, Clermont Ferrand, France
    Fundam Clin Pharmacol 24:139-60. 2010
    ....
  40. ncbi request reprint Performance of asialotransferrin in detecting alcohol abuse
    Raymund Schwan
    Department of Psychiatry, University Hospital, Clermont Ferrand, France
    Alcohol Clin Exp Res 29:81-3. 2005
    ..The present study evaluated the performance of asialotransferrin, a newly proposed biomarker for alcohol use disorders, in detecting alcohol abuse and alcohol dependence...
  41. ncbi request reprint Efficacy and safety of hydroxyzine in the treatment of generalized anxiety disorder: a 3-month double-blind study
    Pierre Michel Llorca
    Hopital Gabriel Montpied, Clermont Ferrand, France
    J Clin Psychiatry 63:1020-7. 2002
    ..The aim of the current study was to confirm those positive results over a 3-month period in adult outpatients...
  42. ncbi request reprint Tardive dyskinesia and glucid metabolism
    Georges Brousse
    CHU Clermont Ferrand, Service de Psychiatrie B, rue Montalembert, France
    Hum Psychopharmacol 22:373-80. 2007
    ..A role of insulin-dependent diabetes in the onset of tardive dyskinesia has been reported and relies on weak physiopathological evidence...
  43. doi request reprint The "Functional Remission of General Schizophrenia" (FROGS) scale: development and validation of a new questionnaire
    Pierre Michel Llorca
    Centre Hospitalier Universitaire, Clermont Ferrand, France
    Schizophr Res 113:218-25. 2009
    ..Further work is required to measure the acceptability, predictive validity, sensitivity to change, and stability of the factor structure of the FROGS...
  44. pmc Measuring preventive procedures by French GPs: an observational survey
    Marie Blanquet
    centre hospitalier universitaire de Clermont Ferrand, Clermont Ferrand, France
    Br J Gen Pract 61:e31-41. 2011
    ..Prevention has become a legal obligation for French GPs, since a law was passed in March 2002...
  45. doi request reprint Psychopathological features of a patient population of targets of workplace bullying
    Georges Brousse
    CHU Clermont Ferrand, Pôle Urgences, Clermont Ferrand, F63001 France
    Occup Med (Lond) 58:122-8. 2008
    ..A strong association between workplace bullying and subsequent anxiety and depression, indicated by empirical research, suggests that bullying is an aetiological factor for mental health problems...
  46. doi request reprint Adherence to guidelines by French psychiatrists in their real world of clinical practice
    Ludovic Samalin
    Centre Hospitalier Universitaire, Clermont Ferrand, France
    J Nerv Ment Dis 199:239-43. 2011
    ..Guidelines for treatment of bipolar disorder are not frequently used. French psychiatrists' age and practice type are the most important variables correlated to the level of use of guidelines...
  47. pmc Impact of practitioner's training in the management of alcohol dependence: a quasi-experimental 18-month follow-up study
    Laurent Malet
    CHU Clermont Ferrand, Clermont Ferrand, F 63000, France INSERM, U669, Paris, F 75014, France
    Subst Abuse Treat Prev Policy 1:18. 2006
    ..Our purpose was to assess the impact of a multifaceted intervention by trained GPs in the management of alcohol-dependent patients...
  48. pmc Treatment in hospital for alcohol-dependent patients decreases attentional bias
    Valentin Flaudias
    Clermont Universite, EA 7280 NPsy Sydo, Clermont Ferrand, France Pôle Psychiatrie B, CHU Gabriel Montpied, Clermont Ferrand, France
    Neuropsychiatr Dis Treat 9:773-9. 2013
    ..The goal of the current study was to examine modification of AB during specialized hospitalization for alcohol dependence, with the suppression of a training bias that could be present in within-subject design...
  49. pmc Asenapine in bipolar I disorder: evidence and place in patient management
    Ludovic Samalin
    centre hospitalier universitaire de Clermont Ferrand, Psychiatry B, 58, rue Montalembert, Clermont Ferrand 63000, France
    Ther Adv Chronic Dis 4:5-14. 2013
    ..This tolerability profile confirms the heterogeneity of the second-generation antipsychotic class and supports the view of some authors for the need to re-evaluate the boundaries of this group...
  50. ncbi request reprint [The limits of patient education in short-term hospitalization: the case of cardiovascular patients]
    Yacine Thiam
    Laboratoire Perinatalite, Pratiques et Developpement, Clermont Ferrand, France
    Sante Publique 24:291-302. 2012
    ..As a result, short-term hospitalization may not be conducive to the mobilization of patients' cognitive and emotional capacities in a therapeutic education program...
  51. ncbi request reprint Recurrent herpes and post-traumatic stress disorder
    Georges Brousse
    CHU Clermont Ferrand, Pôle Urgences, Clermont Ferrand, France
    Herpes 14:72-4. 2007
    ..The patient did not experience any further herpes outbreaks for about 10 months. Control of stress disorders in recurrent herpes is discussed from a therapeutic perspective...
  52. doi request reprint Second meeting of the French CEIP (Centres d'Evaluation et d'Information sur la Pharmacodépendance). Part II: benzodiazepine withdrawal
    Nicolas Authier
    CEIP associé, Service de Pharmacologie, CHU Clermont Ferrand, Clermont Ferrand, France
    Therapie 64:365-70. 2009
    ..However more controlled clinical trials are needed to promote adequate and optimal patient care in management of benzodiazepine withdrawing...
  53. doi request reprint CANABIC: CANnabis and Adolescents: effect of a Brief Intervention on their Consumption--study protocol for a randomized controlled trial
    Catherine Laporte
    Department of General Medicine, Faculty of Medicine of Clermont Ferrand, 28 Place Henri Dunant, 63000 Clermont Ferrand, France
    Trials 15:40. 2014
    ..The aim of the CANABIC study is to measure the impact of a BI carried out by a GP on the consumption of cannabis by adolescents of 15 to 25 years of age...
  54. pmc Occult maternal exposure to environmental tobacco smoke exposure
    Ingrid de Chazeron
    Department of Psychiatry B, CHU Clermont Ferrand, France
    Tob Control 16:64-5. 2007
    ..The discrepancy between self-reported environmental tobacco smoke exposure and cotinine levels in pregnant non-smokers in France was examined...
  55. ncbi request reprint Treatment of schizophrenia with long-acting injectable risperidone: a 12-month open-label trial of the first long-acting second-generation antipsychotic
    W Wolfgang Fleischhacker
    Department of Biological Psychiatry, Innsbruck University Clinics, Anichstrasse 35, 6020 Innsbruck, Austria
    J Clin Psychiatry 64:1250-7. 2003
    ..The long-term safety and efficacy of long-acting injectable risperidone, the first long-acting second-generation antipsychotic, were evaluated in stable patients with schizophrenia...
  56. ncbi request reprint Efficacy and safety of direct transition to risperidone long-acting injectable in patients treated with various antipsychotic therapies
    Hans Jurgen Moller
    Department of Psychiatry, University of Munich, Germany
    Int Clin Psychopharmacol 20:121-30. 2005
    ..Direct initiation of RLAI was effective and well tolerated. RLAI provides an advancement in the treatment options available for a wide range of patients requiring long-term antipsychotic therapy...
  57. ncbi request reprint Bilateral deep brain stimulation of the globus pallidus to treat tardive dyskinesia
    Philippe Damier
    Centre Hospitalier Universitaire de Nantes, centre d investigation clinique, Nantes, France
    Arch Gen Psychiatry 64:170-6. 2007
    ..Tardive dyskinesia (TD) is a common and potentially disabling disorder induced by use of antipsychotic drugs for which medical treatment often gives disappointing results...
  58. ncbi request reprint Effects of cyamemazine on hERG, INa, ICa, Ito, Isus and IK1 channel currents, and on the QTc interval in guinea pigs
    William Crumb
    Zenas Technologies, New Orleans, LA, USA
    Eur J Pharmacol 532:270-8. 2006
    ..These non-clinical findings confirm the excellent cardiac safety records of cyamemazine during its 30 years of extensive therapeutic use...