Gaelle Fromont

Summary

Affiliation: CHU de Poitiers
Country: France

Publications

  1. ncbi 8q24 amplification is associated with Myc expression and prostate cancer progression and is an independent predictor of recurrence after radical prostatectomy
    Gaelle Fromont
    Department of Pathology, CHU Universite de Poitiers, 86000 Poitiers, France
    Hum Pathol 44:1617-23. 2013
  2. doi BCAR1 expression improves prediction of biochemical reccurence after radical prostatectomy
    Gaelle Fromont
    Department of Pathology, CHU Universite de Poitiers, 86000 Poitiers, France
    Prostate 72:1359-65. 2012
  3. doi Biological significance of perineural invasion (PNI) in prostate cancer
    Gaelle Fromont
    Service d Anatomie Pathologique, CHU, Universite de Poitiers, Poitiers, France
    Prostate 72:542-8. 2012
  4. doi Pathologic reassessment of prostate cancer surgical specimens before molecular retrospective studies
    Gaelle Fromont
    Department of Pathology, CHU Universite de Poitiers, Poitiers, France
    Clin Cancer Res 17:836-40. 2011
  5. ncbi Revisiting the immunophenotype of nephrogenic adenoma
    Gaelle Fromont
    Department of Pathology, CHU Universite de Poitiers, Poitiers, France
    Am J Surg Pathol 33:1654-8. 2009
  6. ncbi BCAR1 expression in prostate cancer: association with 16q23 LOH status, tumor progression and EGFR/KAI1 staining
    Gaelle Fromont
    CeRePP, EA 3104, Universite Paris VII, Paris, France
    Prostate 67:268-73. 2007
  7. ncbi Allelic loss at 16q23.2 is associated with good prognosis in high grade prostate cancer
    Gaelle Fromont
    CeRePP, EA 3104, Universite Paris VII, and Department of Urology, Hopital Tenon, Paris, France
    Prostate 65:341-6. 2005
  8. ncbi Molecular profiling of benign prostatic hyperplasia using a large scale real-time reverse transcriptase-polymerase chain reaction approach
    Gaelle Fromont
    CeRePP EA 3104, Universite Paris 7 UFR Biomédicale, Paris, France
    J Urol 172:1382-5. 2004
  9. ncbi Terminal urothelium differentiation of engineered neoureter after in vivo maturation in the "omental bioreactor"
    Herve Baumert
    Department of Urology, Paris Saint Joseph Hospital Trust, Paris, France
    Eur Urol 52:1492-8. 2007
  10. ncbi Differential expression of genes related to androgen and estrogen metabolism in hereditary versus sporadic prostate cancer
    Gaelle Fromont
    Centre de Recherche sur les Pathologies Prostatiques, Paris, France
    Cancer Epidemiol Biomarkers Prev 17:1505-9. 2008

Collaborators

Detail Information

Publications38

  1. ncbi 8q24 amplification is associated with Myc expression and prostate cancer progression and is an independent predictor of recurrence after radical prostatectomy
    Gaelle Fromont
    Department of Pathology, CHU Universite de Poitiers, 86000 Poitiers, France
    Hum Pathol 44:1617-23. 2013
    ..The MYC amplification status could constitute a useful prognostic tool for patients treated by radical prostatectomy, particularly for those with d'Amico intermediate risk, whose clinical behavior is currently difficult to predict. ..
  2. doi BCAR1 expression improves prediction of biochemical reccurence after radical prostatectomy
    Gaelle Fromont
    Department of Pathology, CHU Universite de Poitiers, 86000 Poitiers, France
    Prostate 72:1359-65. 2012
    ....
  3. doi Biological significance of perineural invasion (PNI) in prostate cancer
    Gaelle Fromont
    Service d Anatomie Pathologique, CHU, Universite de Poitiers, Poitiers, France
    Prostate 72:542-8. 2012
    ..In order to better understand the biological significance of perineural invasion (PNI) in prostate cancer, we aimed to analyze in situ the expression of molecules involved in tumor growth or nerve trophicity...
  4. doi Pathologic reassessment of prostate cancer surgical specimens before molecular retrospective studies
    Gaelle Fromont
    Department of Pathology, CHU Universite de Poitiers, Poitiers, France
    Clin Cancer Res 17:836-40. 2011
    ..The retrospective use of prostate cancer tissue is crucial to design tumor marker prognostic studies. We hypothesize that comparison between recent and more historical cases could introduce biases due to stage and grade migration upon time...
  5. ncbi Revisiting the immunophenotype of nephrogenic adenoma
    Gaelle Fromont
    Department of Pathology, CHU Universite de Poitiers, Poitiers, France
    Am J Surg Pathol 33:1654-8. 2009
    ....
  6. ncbi BCAR1 expression in prostate cancer: association with 16q23 LOH status, tumor progression and EGFR/KAI1 staining
    Gaelle Fromont
    CeRePP, EA 3104, Universite Paris VII, Paris, France
    Prostate 67:268-73. 2007
    ....
  7. ncbi Allelic loss at 16q23.2 is associated with good prognosis in high grade prostate cancer
    Gaelle Fromont
    CeRePP, EA 3104, Universite Paris VII, and Department of Urology, Hopital Tenon, Paris, France
    Prostate 65:341-6. 2005
    ..2 is an independent marker of good prognosis in breast cancer. In the present study, we evaluated the clinical relevance of 16q23.2 LOH in prostate cancer, together with other LOH frequently associated with this disease...
  8. ncbi Molecular profiling of benign prostatic hyperplasia using a large scale real-time reverse transcriptase-polymerase chain reaction approach
    Gaelle Fromont
    CeRePP EA 3104, Universite Paris 7 UFR Biomédicale, Paris, France
    J Urol 172:1382-5. 2004
    ....
  9. ncbi Terminal urothelium differentiation of engineered neoureter after in vivo maturation in the "omental bioreactor"
    Herve Baumert
    Department of Urology, Paris Saint Joseph Hospital Trust, Paris, France
    Eur Urol 52:1492-8. 2007
    ..We investigated whether omental maturation of a seeded construct in a pig model could achieve terminal differentiation of the urothelium to allow construction of a stricture-free neoureter...
  10. ncbi Differential expression of genes related to androgen and estrogen metabolism in hereditary versus sporadic prostate cancer
    Gaelle Fromont
    Centre de Recherche sur les Pathologies Prostatiques, Paris, France
    Cancer Epidemiol Biomarkers Prev 17:1505-9. 2008
    ..03). This differential expression of AR and ERA suggests that a specific pattern of hormone receptors is associated with hereditary predisposition to prostate cancer...
  11. ncbi Tissue microarray analysis of the prognostic value of E-cadherin, Ki67, p53, p27, survivin and MSH2 expression in upper urinary tract transitional cell carcinoma
    Gaelle Fromont
    Institut Mutualiste Montsouris, Paris, France
    Eur Urol 48:764-70. 2005
    ..Our purpose was to establish whether the expression of Ki67, p53, p27, E-cadherin, survivin or MSH2 can provide prognostic information in UUT-TCC...
  12. ncbi Effect of genetic variability within 8q24 on aggressiveness patterns at diagnosis and familial status of prostate cancer
    Olivier Cussenot
    CeRePP, Tenon Hospital, Paris, France
    Clin Cancer Res 14:5635-9. 2008
    ..Recently, two independent loci located at 8q24 that contribute to prostate cancer risk in men of European origin were identified...
  13. ncbi Differential expression of the semaphorin 3A pathway in prostatic cancer
    Mokrane Yacoub
    CeRePP, Paris, France
    Histopathology 55:392-8. 2009
    ..To analyse the expression pattern of the semaphorin 3A (Sema3A) pathway, including the receptor neuropilin 1 (NRP1) and its ligands the 'antitumoral' Sema3A and the 'protumoral' vascular endothelial growth factor (VEGF)in prostatic cancer...
  14. ncbi Intraoperative frozen section analysis during nerve sparing laparoscopic radical prostatectomy: feasibility study
    Gaelle Fromont
    Department of Pathology, Institut Montsouris, 42 Boulevard Jourdan, 75014 Paris, France
    J Urol 170:1843-6. 2003
    ..Nerve sparing radical prostatectomy may allow preservation of potency but it can increase positive surgical margins. We used intraoperative frozen section (IFS) analysis to monitor the nerve sparing procedure in laparoscopic prostatectomy...
  15. doi Prognostic interest in discriminating muscularis mucosa invasion (T1a vs T1b) in nonmuscle invasive bladder carcinoma: French national multicenter study with central pathology review
    Morgan Roupret
    Academic Departments of Urology, Pitie Salpetriere Hospital, Assistance Publique Hopitaux de Paris, Paris, France
    J Urol 189:2069-76. 2013
    ..Predictive factors of T1 nonmuscle invasive bladder cancer evolution that could guide treatment decision making are lacking. We assessed the prognostic value of muscularis mucosa invasion in nonmuscle invasive bladder cancer...
  16. doi Expression of estrogen related proteins in hormone refractory prostate cancer: association with tumor progression
    Olivier Celhay
    Service d Urologie, Centre Hospitalier Universitaire Université de Poitiers, Poitiers, France
    J Urol 184:2172-8. 2010
    ..We investigated the expression of proteins related to androgen and estrogen metabolism in paired prostate cancer samples collected before androgen deprivation therapy and after hormonal relapse...
  17. ncbi Differential expression of 37 selected genes in hormone-refractory prostate cancer using quantitative taqman real-time RT-PCR
    Gaelle Fromont
    Centre d Etude et de Recherche en Pathologie Prostatique 3104, Universite Paris VII, Paris, France
    Int J Cancer 114:174-81. 2005
    ..Progression of prostate cancer to the hormone-refractory state is associated with differential gene expression, which may prove useful for both understanding disease progression and the development of new therapeutic approaches...
  18. ncbi Impact of margin size on the incidence of local residual tumor after laparoscopic radical prostatectomy
    Gaelle Fromont
    Department of Pathology, Institut Montsouris, Paris, France
    J Urol 172:1845-7. 2004
    ..In cases of positive surgical margin (SMs) the corresponding neurovascular bundle (NVB) was resected. We evaluated the impact of several biological and pathological parameters on the incidence of local residual tumor in the NVB...
  19. ncbi Outcome after radical prostatectomy in young men with or without a family history of prostate cancer
    Morgan Roupret
    Department of Urology of GHU EST, Assistance Publique Hopitaux de Paris, University Paris VI, Paris, France
    Urology 67:1028-32. 2006
    ..To establish the cancer control afforded by radical prostatectomy in patients aged 50 years or younger with sporadic, familial, or hereditary prostate cancer...
  20. doi DNA-PKcs expression predicts response to radiotherapy in prostate cancer
    Patrick Bouchaert
    Department of Pathology, CHU Universite de Poitiers, Poitiers, France
    Int J Radiat Oncol Biol Phys 84:1179-85. 2012
    ..The expression of the nonhomologous end-joining pathway has never been studied in prostate cancer, and its prognostic value for patients undergoing radiotherapy remains unknown...
  21. doi Percentage of positive biopsy cores at the onset of hormone therapy for prostate cancer: prognostic significance
    Guillaume Normand
    Department of Urology, Centre Hospitalier Universitaire, Poitiers, France
    Urol Int 83:160-5. 2009
    ..We hypothesized that it would predict time to hormonal independence and survival in prostate cancer patients treated with androgen deprivation therapy (ADT)...
  22. ncbi Allelic losses in localized prostate cancer: association with prognostic factors
    Gaelle Fromont
    CeRePP, EA 3104, Universite Paris VII, France
    J Urol 170:1394-7. 2003
    ..We performed LOH analysis on 6 chromosomal regions of interest in localized CaP to obtain an overview of allelic losses in organ confined tumors and test the association with the usual prognostic factors...
  23. doi Ductal carcinoma of the prostate shows a different immunophenotype from high grade acinar cancer
    Pauline Jardel
    Department of Pathology, CHU Universite de Poitiers, Poitiers, France Department of Radiotherapy, CHU Universite de Poitiers, Poitiers, France
    Histopathology 63:57-63. 2013
    ..We aimed to analyze the expression of molecules involved in either hormonal signalling or androgen independent pathways, in DC compared to high grade AC...
  24. doi Mesonephric remnant hyperplasia: an unusual benign mimicker of prostate cancer
    Mokrane Yacoub
    Services d anatomie pathologique, CHU Jean Bernard, rue de la Miletrie, 86000 Poitiers, France
    Ann Diagn Pathol 13:402-4. 2009
    ..The presence of MRs in prostate tissues may be more common than appreciated or reported. Once the possibility is considered, the diagnosis is easily confirmed using immunochemistry...
  25. ncbi Combination of polymorphisms from genes related to estrogen metabolism and risk of prostate cancers: the hidden face of estrogens
    Olivier Cussenot
    Centre de Recherche pour les Pathologies Prostatiques, Tenon Hospital, Paris, France
    J Clin Oncol 25:3596-602. 2007
    ..The association between common functional polymorphisms from the CYP17, CYP19, CYP1B1, and COMT genes involved in the estrogen metabolism and the risk of prostate carcinoma was evaluated...
  26. ncbi Impact of learning curve in laparoscopic radical prostatectomy on margin status: prospective study of first 100 procedures performed by one surgeon
    Herve Baumert
    Department of Urology, Institut Mutualiste Montsouris, Paris, France
    J Endourol 18:173-6. 2004
    ..To describe the experience of a single surgeon with his first 100 laparoscopic radical prostatectomies and determine the impact of the learning curve on the surgical margin status according to the rate of nervesparing procedures...
  27. ncbi Accuracy of the routine detection of mutation in mismatch repair genes in patients with susceptibility to hereditary upper urinary tract transitional cell carcinoma
    Morgan Roupret
    Department of Urology of Tenon Hospital, Paris, France
    BJU Int 96:149-51. 2005
    ....
  28. ncbi Epithelial phenotypes in the developing human prostate
    Guy Letellier
    Service de Pediatrie, Centre Hospitalier Universitaire Université de Poitiers, Poitiers, France
    J Histochem Cytochem 55:885-90. 2007
    ..These results indicate that most fetal epithelial prostatic cells exhibit the phenotype of TA cells, suggesting their regulatory function in prostate development...
  29. ncbi Microsatellite instability as predictor of survival in patients with invasive upper urinary tract transitional cell carcinoma
    Morgan Roupret
    Department of Urology, Tenon Hospital, AP HP, Paris, France
    Urology 65:1233-7. 2005
    ..UUT-TCC has a poor prognosis (overall survival less than 50% at 5 years)...
  30. ncbi Renal translocation carcinomas: clinicopathologic, immunohistochemical, and gene expression profiling analysis of 31 cases with a review of the literature
    Philippe Camparo
    HIA Val de Grace, Van Andel Research Institute, Paris, France
    Am J Surg Pathol 32:656-70. 2008
    ..Our results suggest that these differentially expressed genes may serve as novel diagnostic or prognostic markers...
  31. ncbi Expression patterns of candidate susceptibility genes HNF1β and CtBP2 in prostate cancer: association with tumor progression
    Celine Debiais-Delpech
    Department of Pathology, CHU Universite de Poitiers, Poitiers, France
    Urol Oncol 32:426-32. 2014
    ..Except for MSMB, the clinicopathological significance of these genes has not been investigated. We therefore aimed to analyze their expression in PCa tissues, in relation with tumor progression and aggressiveness...
  32. pmc Expression of follicle-stimulating hormone receptor by the vascular endothelium in tumor metastases
    Ahsan Siraj
    Inserm Equipe Angiogenèse Tumorale, Institut Curie, Centre de Recherche, Département Recherche Translationnelle, 26 Rue d Ulm, 75005, Paris, France
    BMC Cancer 13:246. 2013
    ..The Follicle Stimulating Hormone receptor (FSHR) is expressed by the vascular endothelium in a wide range of human tumors. It was not determined however if FSHR is present in metastases which are responsible for the terminal illness...
  33. doi Altered expression of the gap junction protein connexin43 is associated with papillary thyroid carcinomas when compared with other noncancer pathologies of the thyroid
    Claudia Dominguez
    Department of Visceral Surgery, Jean Bernard Hospital, University Hospital Center CHU of Poitiers, Poitiers, France
    Thyroid 21:1057-66. 2011
    ..To verify their possible involvement in thyroid pathologies, the expression of connexin43 (Cx43), the major Cx in the human thyroid, was evaluated in a variety of diseases including cancer...
  34. ncbi Intra renal arterial injection of autologous mesenchymal stem cells in an ovine model in the postischemic kidney
    Luc Behr
    INSERM, U872, Centre de Recherche des Cordeliers, Universite Pierre et Marie Curie Paris 6, UMR S872, Universite Paris Descartes, UMR S872, Paris, France
    Nephron Physiol 107:p65-76. 2007
    ....
  35. doi Prognostic value of O6-methylguanine-DNA methyltransferase status in glioblastoma patients, assessed by five different methods
    Lucie Karayan-Tapon
    Universite de Poitiers, 86021 Poitiers, France
    J Neurooncol 97:311-22. 2010
    ..These results confirm the prognostic value of MGMT promoter methylation in glioblastoma patients initially treated with TMZ. SQ-MSP allowed better discrimination than classical MSP, and pyrosequencing represented a good option...
  36. ncbi Cystectomy with prostate sparing for bladder cancer in 100 patients: 10-year experience
    Guy Vallancien
    Department of Urology, Institut Montsouris and the Universite Pierre et Marie Curie, Paris, France
    J Urol 168:2413-7. 2002
    ..To minimize the risk of incontinence and impotence without compromising oncological outcome, we performed prostate sparing surgery during radical cystectomy for bladder cancer...
  37. ncbi Solitary intestinal fibromatosis associated with congenital ileal atresia
    Alix Coulon
    Department of Pathology, CHU Universite de Poitiers, Poitiers, France
    J Pediatr Surg 42:1942-5. 2007
    ..The spindle cell proliferation showed a high apoptotic index contrasting with a low proliferation rate, suggesting that the tumor may have undergone focal and spontaneous regression, leading to intestinal atresia...
  38. ncbi Development of a seeded scaffold in the great omentum: feasibility of an in vivo bioreactor for bladder tissue engineering
    Herve Baumert
    Department of Urology, Paris Saint Joseph Hospital Trust, Paris, France
    Eur Urol 52:884-90. 2007
    ..However, one of the main problems is to limit the development of ischaemic fibrosis during tissue maturation. We describe a model using the omentum as an in vivo bioreactor for a previously seeded scaffold...