Research Topics
Genomes and GenesSpecies | Gaelle FromontSummaryAffiliation: CHU de Poitiers Country: France Publications
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Publications
BCAR1 expression improves prediction of biochemical reccurence after radical prostatectomyGaelle Fromont
Department of Pathology, CHU Universite de Poitiers, 86000 Poitiers, France
Prostate 72:1359-65. 2012....- Biological significance of perineural invasion (PNI) in prostate cancerGaelle Fromont
Service d Anatomie Pathologique, CHU, Universite de Poitiers, Poitiers, France
Prostate 72:542-8. 2012..In order to better understand the biological significance of perineural invasion (PNI) in prostate cancer, we aimed to analyze in situ the expression of molecules involved in tumor growth or nerve trophicity... 
Allelic loss at 16q23.2 is associated with good prognosis in high grade prostate cancerGaelle Fromont
CeRePP, EA 3104, Universite Paris VII, and Department of Urology, Hopital Tenon, Paris, France
Prostate 65:341-6. 2005..2 is an independent marker of good prognosis in breast cancer. In the present study, we evaluated the clinical relevance of 16q23.2 LOH in prostate cancer, together with other LOH frequently associated with this disease...- Pathologic reassessment of prostate cancer surgical specimens before molecular retrospective studiesGaelle Fromont
Department of Pathology, CHU Universite de Poitiers, Poitiers, France
Clin Cancer Res 17:836-40. 2011..The retrospective use of prostate cancer tissue is crucial to design tumor marker prognostic studies. We hypothesize that comparison between recent and more historical cases could introduce biases due to stage and grade migration upon time... - BCAR1 expression in prostate cancer: association with 16q23 LOH status, tumor progression and EGFR/KAI1 stainingGaelle Fromont
CeRePP, EA 3104, Universite Paris VII, Paris, France
Prostate 67:268-73. 2007.... - Revisiting the immunophenotype of nephrogenic adenomaGaelle Fromont
Department of Pathology, CHU Universite de Poitiers, Poitiers, France
Am J Surg Pathol 33:1654-8. 2009.... - Terminal urothelium differentiation of engineered neoureter after in vivo maturation in the "omental bioreactor"Herve Baumert
Department of Urology, Paris Saint Joseph Hospital Trust, Paris, France
Eur Urol 52:1492-8. 2007..We investigated whether omental maturation of a seeded construct in a pig model could achieve terminal differentiation of the urothelium to allow construction of a stricture-free neoureter... - Molecular profiling of benign prostatic hyperplasia using a large scale real-time reverse transcriptase-polymerase chain reaction approachGaelle Fromont
CeRePP EA 3104, Universite Paris 7 UFR Biomédicale, Paris, France
J Urol 172:1382-5. 2004.... - Tissue microarray analysis of the prognostic value of E-cadherin, Ki67, p53, p27, survivin and MSH2 expression in upper urinary tract transitional cell carcinomaGaelle Fromont
Institut Mutualiste Montsouris, Paris, France
Eur Urol 48:764-70. 2005..Our purpose was to establish whether the expression of Ki67, p53, p27, E-cadherin, survivin or MSH2 can provide prognostic information in UUT-TCC... - Differential expression of genes related to androgen and estrogen metabolism in hereditary versus sporadic prostate cancerGaelle Fromont
Centre de Recherche sur les Pathologies Prostatiques, Paris, France
Cancer Epidemiol Biomarkers Prev 17:1505-9. 2008..03). This differential expression of AR and ERA suggests that a specific pattern of hormone receptors is associated with hereditary predisposition to prostate cancer... - Effect of genetic variability within 8q24 on aggressiveness patterns at diagnosis and familial status of prostate cancerOlivier Cussenot
CeRePP, Tenon Hospital, Paris, France
Clin Cancer Res 14:5635-9. 2008..Recently, two independent loci located at 8q24 that contribute to prostate cancer risk in men of European origin were identified... - Intraoperative frozen section analysis during nerve sparing laparoscopic radical prostatectomy: feasibility studyGaelle Fromont
Department of Pathology, Institut Montsouris, 42 Boulevard Jourdan, 75014 Paris, France
J Urol 170:1843-6. 2003..Nerve sparing radical prostatectomy may allow preservation of potency but it can increase positive surgical margins. We used intraoperative frozen section (IFS) analysis to monitor the nerve sparing procedure in laparoscopic prostatectomy... - Expression of estrogen related proteins in hormone refractory prostate cancer: association with tumor progressionOlivier Celhay
Service d Urologie, Centre Hospitalier Universitaire Université de Poitiers, Poitiers, France
J Urol 184:2172-8. 2010..We investigated the expression of proteins related to androgen and estrogen metabolism in paired prostate cancer samples collected before androgen deprivation therapy and after hormonal relapse... - Differential expression of the semaphorin 3A pathway in prostatic cancerMokrane Yacoub
CeRePP, Paris, France
Histopathology 55:392-8. 2009..To analyse the expression pattern of the semaphorin 3A (Sema3A) pathway, including the receptor neuropilin 1 (NRP1) and its ligands the 'antitumoral' Sema3A and the 'protumoral' vascular endothelial growth factor (VEGF)in prostatic cancer... - Differential expression of 37 selected genes in hormone-refractory prostate cancer using quantitative taqman real-time RT-PCRGaelle Fromont
Centre d Etude et de Recherche en Pathologie Prostatique 3104, Universite Paris VII, Paris, France
Int J Cancer 114:174-81. 2005..Progression of prostate cancer to the hormone-refractory state is associated with differential gene expression, which may prove useful for both understanding disease progression and the development of new therapeutic approaches... - Impact of margin size on the incidence of local residual tumor after laparoscopic radical prostatectomyGaelle Fromont
Department of Pathology, Institut Montsouris, Paris, France
J Urol 172:1845-7. 2004..In cases of positive surgical margin (SMs) the corresponding neurovascular bundle (NVB) was resected. We evaluated the impact of several biological and pathological parameters on the incidence of local residual tumor in the NVB... - Outcome after radical prostatectomy in young men with or without a family history of prostate cancerMorgan Roupret
Department of Urology of GHU EST, Assistance Publique Hopitaux de Paris, University Paris VI, Paris, France
Urology 67:1028-32. 2006..To establish the cancer control afforded by radical prostatectomy in patients aged 50 years or younger with sporadic, familial, or hereditary prostate cancer... - DNA-PKcs expression predicts response to radiotherapy in prostate cancerPatrick Bouchaert
Department of Pathology, CHU Universite de Poitiers, Poitiers, France
Int J Radiat Oncol Biol Phys 84:1179-85. 2012..The expression of the nonhomologous end-joining pathway has never been studied in prostate cancer, and its prognostic value for patients undergoing radiotherapy remains unknown... - Percentage of positive biopsy cores at the onset of hormone therapy for prostate cancer: prognostic significanceGuillaume Normand
Department of Urology, Centre Hospitalier Universitaire, Poitiers, France
Urol Int 83:160-5. 2009..We hypothesized that it would predict time to hormonal independence and survival in prostate cancer patients treated with androgen deprivation therapy (ADT)... - Allelic losses in localized prostate cancer: association with prognostic factorsGaelle Fromont
CeRePP, EA 3104, Universite Paris VII, France
J Urol 170:1394-7. 2003..We performed LOH analysis on 6 chromosomal regions of interest in localized CaP to obtain an overview of allelic losses in organ confined tumors and test the association with the usual prognostic factors... - Mesonephric remnant hyperplasia: an unusual benign mimicker of prostate cancerMokrane Yacoub
Services d anatomie pathologique, CHU Jean Bernard, rue de la Miletrie, 86000 Poitiers, France
Ann Diagn Pathol 13:402-4. 2009..The presence of MRs in prostate tissues may be more common than appreciated or reported. Once the possibility is considered, the diagnosis is easily confirmed using immunochemistry... - Impact of learning curve in laparoscopic radical prostatectomy on margin status: prospective study of first 100 procedures performed by one surgeonHerve Baumert
Department of Urology, Institut Mutualiste Montsouris, Paris, France
J Endourol 18:173-6. 2004..To describe the experience of a single surgeon with his first 100 laparoscopic radical prostatectomies and determine the impact of the learning curve on the surgical margin status according to the rate of nervesparing procedures... - Combination of polymorphisms from genes related to estrogen metabolism and risk of prostate cancers: the hidden face of estrogensOlivier Cussenot
Centre de Recherche pour les Pathologies Prostatiques, Tenon Hospital, Paris, France
J Clin Oncol 25:3596-602. 2007..The association between common functional polymorphisms from the CYP17, CYP19, CYP1B1, and COMT genes involved in the estrogen metabolism and the risk of prostate carcinoma was evaluated... - Accuracy of the routine detection of mutation in mismatch repair genes in patients with susceptibility to hereditary upper urinary tract transitional cell carcinomaMorgan Roupret
Department of Urology of Tenon Hospital, Paris, France
BJU Int 96:149-51. 2005.... - Epithelial phenotypes in the developing human prostateGuy Letellier
Service de Pediatrie, Centre Hospitalier Universitaire Université de Poitiers, Poitiers, France
J Histochem Cytochem 55:885-90. 2007..These results indicate that most fetal epithelial prostatic cells exhibit the phenotype of TA cells, suggesting their regulatory function in prostate development... - Renal translocation carcinomas: clinicopathologic, immunohistochemical, and gene expression profiling analysis of 31 cases with a review of the literaturePhilippe Camparo
HIA Val de Grace, Van Andel Research Institute, Paris, France
Am J Surg Pathol 32:656-70. 2008..Our results suggest that these differentially expressed genes may serve as novel diagnostic or prognostic markers... - Microsatellite instability as predictor of survival in patients with invasive upper urinary tract transitional cell carcinomaMorgan Roupret
Department of Urology, Tenon Hospital, AP HP, Paris, France
Urology 65:1233-7. 2005..UUT-TCC has a poor prognosis (overall survival less than 50% at 5 years)... - Altered expression of the gap junction protein connexin43 is associated with papillary thyroid carcinomas when compared with other noncancer pathologies of the thyroidClaudia Dominguez
Department of Visceral Surgery, Jean Bernard Hospital, University Hospital Center CHU of Poitiers, Poitiers, France
Thyroid 21:1057-66. 2011..To verify their possible involvement in thyroid pathologies, the expression of connexin43 (Cx43), the major Cx in the human thyroid, was evaluated in a variety of diseases including cancer... - Intra renal arterial injection of autologous mesenchymal stem cells in an ovine model in the postischemic kidneyLuc Behr
INSERM, U872, Centre de Recherche des Cordeliers, Universite Pierre et Marie Curie Paris 6, UMR S872, Universite Paris Descartes, UMR S872, Paris, France
Nephron Physiol 107:p65-76. 2007.... - Prognostic value of O6-methylguanine-DNA methyltransferase status in glioblastoma patients, assessed by five different methodsLucie Karayan-Tapon
Universite de Poitiers, 86021 Poitiers, France
J Neurooncol 97:311-22. 2010..These results confirm the prognostic value of MGMT promoter methylation in glioblastoma patients initially treated with TMZ. SQ-MSP allowed better discrimination than classical MSP, and pyrosequencing represented a good option... - Cystectomy with prostate sparing for bladder cancer in 100 patients: 10-year experienceGuy Vallancien
Department of Urology, Institut Montsouris and the Universite Pierre et Marie Curie, Paris, France
J Urol 168:2413-7. 2002..1%) are impotent. CONCLUSIONS: Cystectomy with prostate sparing for bladder cancer is feasible and offers promising functional results with no additional oncological risk. Careful selection of patients is mandatory... - Solitary intestinal fibromatosis associated with congenital ileal atresiaAlix Coulon
Department of Pathology, CHU Universite de Poitiers, Poitiers, France
J Pediatr Surg 42:1942-5. 2007..The spindle cell proliferation showed a high apoptotic index contrasting with a low proliferation rate, suggesting that the tumor may have undergone focal and spontaneous regression, leading to intestinal atresia... - Development of a seeded scaffold in the great omentum: feasibility of an in vivo bioreactor for bladder tissue engineeringHerve Baumert
Department of Urology, Paris Saint Joseph Hospital Trust, Paris, France
Eur Urol 52:884-90. 2007..However, one of the main problems is to limit the development of ischaemic fibrosis during tissue maturation. We describe a model using the omentum as an in vivo bioreactor for a previously seeded scaffold...