P Derkinderen

Summary

Affiliation: CHU de Nantes
Country: France

Publications

  1. pmc Tyrosine phosphorylation of tau by the SRC family kinases lck and fyn
    Timothy Me Scales
    MRC Centre for Neurodegeneration Research, Department of Neuroscience, Institute of Psychiatry, King s College London, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK
    Mol Neurodegener 6:12. 2011
  2. pmc The microtubule-associated protein tau is phosphorylated by Syk
    Thibaud Lebouvier
    INSERM, U643, Nantes, F 44000, France
    Biochim Biophys Acta 1783:188-92. 2008
  3. doi request reprint Parkinson disease: the enteric nervous system spills its guts
    P Derkinderen
    INSERM U913, 1 Place Alexis Ricordeau, CHU Nantes, 44093 Nantes Cedex 1, France
    Neurology 77:1761-7. 2011
  4. doi request reprint [Enteric nervous system and Parkinson's disease]
    S Paillusson
    INSERM U913, CHU de Nantes, 1, Place Alexis Ricordeau, 44093 Nantes, France
    Rev Med Interne 33:335-8. 2012
  5. doi request reprint Effects of oral administration of rotenone on gastrointestinal functions in mice
    M Tasselli
    INSERM, U913, Nantes, France
    Neurogastroenterol Motil 25:e183-93. 2013
  6. doi request reprint A comparison between colonic submucosa and mucosa to detect Lewy pathology in Parkinson's disease
    H Pouclet
    INSERM, U913, Nantes, France
    Neurogastroenterol Motil 24:e202-5. 2012
  7. doi request reprint Routine colonic biopsies as a new tool to study the enteric nervous system in living patients
    T Lebouvier
    INSERM, U913, Nantes, France
    Neurogastroenterol Motil 22:e11-4. 2010
  8. doi request reprint Neurochemical plasticity in the enteric nervous system of a primate animal model of experimental Parkinsonism
    T Chaumette
    INSERM, U913, Nantes, France
    Neurogastroenterol Motil 21:215-22. 2009
  9. ncbi request reprint [Idiopathic acute transverse myelitis: application of new diagnosis criteria to 17 patients]
    C Lanctin
    Pôle de Neurologie médicale et chirurgicale, Hopital Laennec, CHU de Nantes, Saint Herblain, France
    Rev Neurol (Paris) 162:980-9. 2006
  10. pmc Activity-dependent regulation of tyrosine hydroxylase expression in the enteric nervous system
    J Chevalier
    INSERM, U913, Nantes, F 44093, France
    J Physiol 586:1963-75. 2008

Collaborators

Detail Information

Publications11

  1. pmc Tyrosine phosphorylation of tau by the SRC family kinases lck and fyn
    Timothy Me Scales
    MRC Centre for Neurodegeneration Research, Department of Neuroscience, Institute of Psychiatry, King s College London, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK
    Mol Neurodegener 6:12. 2011
    ..abstract:..
  2. pmc The microtubule-associated protein tau is phosphorylated by Syk
    Thibaud Lebouvier
    INSERM, U643, Nantes, F 44000, France
    Biochim Biophys Acta 1783:188-92. 2008
    ..These results bring another clue to the intriguing overlaps between tauopathies and synucleinopathies and provide new insights into the role of Syk in neuronal physiology...
  3. doi request reprint Parkinson disease: the enteric nervous system spills its guts
    P Derkinderen
    INSERM U913, 1 Place Alexis Ricordeau, CHU Nantes, 44093 Nantes Cedex 1, France
    Neurology 77:1761-7. 2011
    ..In this perspective, we discuss current evidence which indicates that the presence of ENS pathology may by exploited to improve our understanding and management of PD and likely other neurodegenerative disorders...
  4. doi request reprint [Enteric nervous system and Parkinson's disease]
    S Paillusson
    INSERM U913, CHU de Nantes, 1, Place Alexis Ricordeau, 44093 Nantes, France
    Rev Med Interne 33:335-8. 2012
    ..Owing to its accessibility to biopsies, we further discuss the use of the enteric nervous system as an original source of biomarker in Parkinson's disease...
  5. doi request reprint Effects of oral administration of rotenone on gastrointestinal functions in mice
    M Tasselli
    INSERM, U913, Nantes, France
    Neurogastroenterol Motil 25:e183-93. 2013
    ..This study was therefore designed to assess the effects of a chronic oral treatment by rotenone on enteric neurochemical phenotype, gastrointestinal (GI) motility, and intestinal epithelial barrier permeability...
  6. doi request reprint A comparison between colonic submucosa and mucosa to detect Lewy pathology in Parkinson's disease
    H Pouclet
    INSERM, U913, Nantes, France
    Neurogastroenterol Motil 24:e202-5. 2012
    ..The aim of the present research was to determine whether the analysis of the mucosa obtained after microdissection may help improve the sensitivity of colonic biopsies to detect Lewy pathology in the colon of PD patients...
  7. doi request reprint Routine colonic biopsies as a new tool to study the enteric nervous system in living patients
    T Lebouvier
    INSERM, U913, Nantes, France
    Neurogastroenterol Motil 22:e11-4. 2010
    ..This method of analysis of the human ENS will enable us to gain better insight into the characterization of enteric neuropathies in living patients...
  8. doi request reprint Neurochemical plasticity in the enteric nervous system of a primate animal model of experimental Parkinsonism
    T Chaumette
    INSERM, U913, Nantes, France
    Neurogastroenterol Motil 21:215-22. 2009
    ..They further reinforce the observation that lesions of the ENS occur in the course of PD that might be related to the GI dysfunction observed in this pathology...
  9. ncbi request reprint [Idiopathic acute transverse myelitis: application of new diagnosis criteria to 17 patients]
    C Lanctin
    Pôle de Neurologie médicale et chirurgicale, Hopital Laennec, CHU de Nantes, Saint Herblain, France
    Rev Neurol (Paris) 162:980-9. 2006
    ..Prognosis is not well-known...
  10. pmc Activity-dependent regulation of tyrosine hydroxylase expression in the enteric nervous system
    J Chevalier
    INSERM, U913, Nantes, F 44093, France
    J Physiol 586:1963-75. 2008
    ..They could also set the basis for the study of the pathways and mechanisms involved in the neurochemical plasticity observed both during ENS development and in inflammatory enteric neuropathies...
  11. doi request reprint [Non-dopaminergic treatments for Parkinson's disease]
    P Derkinderen
    INSERM, U913, 44093 Nantes, France
    Rev Neurol (Paris) 166:811-5. 2010
    ..In this article, both the pathophysiology and the pharmacological management of these non-dopaminergic symptoms are discussed...