Lionel Couzi

Summary

Affiliation: CHU de Bordeaux
Country: France

Publications

  1. doi request reprint Factors predictive of medication nonadherence after renal transplantation: a French observational study
    Lionel Couzi
    CHU de Bordeaux, Hopital Pellegrin, Service de Nephrologie et Transplantation Renale, Bordeaux, France
    Transplantation 95:326-32. 2013
  2. doi request reprint Preemptive therapy versus valgancyclovir prophylaxis in cytomegalovirus-positive kidney transplant recipients receiving antithymocyte globulin induction
    L Couzi
    Service de Néphrologie Transplantation, Centre Hospitalier Universitaire, Hopital Pellegrin, Bordeaux, France
    Transplant Proc 44:2809-13. 2012
  3. doi request reprint High incidence of anticytomegalovirus drug resistance among D+R- kidney transplant recipients receiving preemptive therapy
    L Couzi
    Centre Hospitalier Universitaire de Bordeaux, Hopital Pellegrin, 33076 Bordeaux, France
    Am J Transplant 12:202-9. 2012
  4. doi request reprint Interpretation of positive flow cytometric crossmatch in the era of the single-antigen bead assay
    Lionel Couzi
    CHU Bordeaux, Hopital Pellegrin, Nephrology, Place Amelie Raba Leon, Bordeaux, France
    Transplantation 91:527-35. 2011
  5. ncbi request reprint An unusual endocarditis-induced crescentic glomerulonephritis treated by plasmapheresis
    L Couzi
    Departement de Nephrologie, Hopital Pellegrin, France
    Clin Nephrol 62:461-4. 2004
  6. ncbi request reprint The immunosuppressor mycophenolic acid kills activated lymphocytes by inducing a nonclassical actin-dependent necrotic signal
    Benjamin Chaigne-Delalande
    Universite de Bordeaux 2, Bordeaux, France
    J Immunol 181:7630-8. 2008
  7. doi request reprint Common features of gammadelta T cells and CD8(+) alphabeta T cells responding to human cytomegalovirus infection in kidney transplant recipients
    Lionel Couzi
    Centre Hospitalier Universitaire de Bordeaux, Bordeaux, France
    J Infect Dis 200:1415-24. 2009
  8. doi request reprint Antibody-dependent anti-cytomegalovirus activity of human γδ T cells expressing CD16 (FcγRIIIa)
    Lionel Couzi
    Universite de Bordeaux, Bordeaux, France
    Blood 119:1418-27. 2012
  9. doi request reprint Therapeutic management of de novo urological malignancy in renal transplant recipients: the experience of the French Department of Urology and Kidney Transplantation from Bordeaux
    Hicham Elkentaoui
    Department of Urology, Centre Hospitalo Universitaire Pellegrin Tripode, 33000, Bordeaux, France
    Urology 75:126-32. 2010
  10. doi request reprint Immunological monitoring of calcineurin inhibitors for predicting cytomegalovirus infection in kidney transplant recipients
    Lionel Couzi
    Service de Nephrologie, CHU Bordeaux, Hopital Pellegrin, CNRS UMR 5164, 146 rue Leo Saignat, Universite Bordeaux 2, INSERM U897, 146, rue Leo Saignat, Bordeaux, France
    Transplantation 86:1060-7. 2008

Collaborators

Detail Information

Publications27

  1. doi request reprint Factors predictive of medication nonadherence after renal transplantation: a French observational study
    Lionel Couzi
    CHU de Bordeaux, Hopital Pellegrin, Service de Nephrologie et Transplantation Renale, Bordeaux, France
    Transplantation 95:326-32. 2013
    ..The objective of this study was to prospectively evaluate the rate of and risk factors for NA in a French cohort of KTRs...
  2. doi request reprint Preemptive therapy versus valgancyclovir prophylaxis in cytomegalovirus-positive kidney transplant recipients receiving antithymocyte globulin induction
    L Couzi
    Service de Néphrologie Transplantation, Centre Hospitalier Universitaire, Hopital Pellegrin, Bordeaux, France
    Transplant Proc 44:2809-13. 2012
    ..In light of this study, preemptive therapy and universal prophylaxis were almost equally effective to prevent CMV infection among R+ KTR receiving ATG induction...
  3. doi request reprint High incidence of anticytomegalovirus drug resistance among D+R- kidney transplant recipients receiving preemptive therapy
    L Couzi
    Centre Hospitalier Universitaire de Bordeaux, Hopital Pellegrin, 33076 Bordeaux, France
    Am J Transplant 12:202-9. 2012
    ..02). In summary, preemptive therapy in D+R- KTR with high CMV loads and antiviral treatment failure was associated with a high incidence of anti-CMV drug resistance...
  4. doi request reprint Interpretation of positive flow cytometric crossmatch in the era of the single-antigen bead assay
    Lionel Couzi
    CHU Bordeaux, Hopital Pellegrin, Nephrology, Place Amelie Raba Leon, Bordeaux, France
    Transplantation 91:527-35. 2011
    ..Prognosis of renal transplants with positive flow cytometric crossmatch (FCXM) remains controversial...
  5. ncbi request reprint An unusual endocarditis-induced crescentic glomerulonephritis treated by plasmapheresis
    L Couzi
    Departement de Nephrologie, Hopital Pellegrin, France
    Clin Nephrol 62:461-4. 2004
    ..In very few cases, plasmapheresis was successfully used for the treatment of infective endocarditis-induced crescentic glomerulonephritis. The pathophysiology and the potential efficiency of plasmapheresis are discussed...
  6. ncbi request reprint The immunosuppressor mycophenolic acid kills activated lymphocytes by inducing a nonclassical actin-dependent necrotic signal
    Benjamin Chaigne-Delalande
    Universite de Bordeaux 2, Bordeaux, France
    J Immunol 181:7630-8. 2008
    ..In addition to its medical interest, this study sheds light on a novel and atypical molecular mechanism leading to necrotic cell death...
  7. doi request reprint Common features of gammadelta T cells and CD8(+) alphabeta T cells responding to human cytomegalovirus infection in kidney transplant recipients
    Lionel Couzi
    Centre Hospitalier Universitaire de Bordeaux, Bordeaux, France
    J Infect Dis 200:1415-24. 2009
    ..The anti-CMV function of these cells was previously demonstrated by their ability to kill CMV-infected cells in vitro...
  8. doi request reprint Antibody-dependent anti-cytomegalovirus activity of human γδ T cells expressing CD16 (FcγRIIIa)
    Lionel Couzi
    Universite de Bordeaux, Bordeaux, France
    Blood 119:1418-27. 2012
    ..Taken together, these data identify a new antiviral function for γδ T cells through cooperation with anti-HCMV IgG that could contribute to surveillance of HCMV reactivation in transplant recipients...
  9. doi request reprint Therapeutic management of de novo urological malignancy in renal transplant recipients: the experience of the French Department of Urology and Kidney Transplantation from Bordeaux
    Hicham Elkentaoui
    Department of Urology, Centre Hospitalo Universitaire Pellegrin Tripode, 33000, Bordeaux, France
    Urology 75:126-32. 2010
    ..To determine and analyze the incidence, prognosis, and therapeutic strategy of de novo urological malignancies in a series of renal transplant recipients (RTRs)...
  10. doi request reprint Immunological monitoring of calcineurin inhibitors for predicting cytomegalovirus infection in kidney transplant recipients
    Lionel Couzi
    Service de Nephrologie, CHU Bordeaux, Hopital Pellegrin, CNRS UMR 5164, 146 rue Leo Saignat, Universite Bordeaux 2, INSERM U897, 146, rue Leo Saignat, Bordeaux, France
    Transplantation 86:1060-7. 2008
    ..Measurement of the biological effects of CNI could provide clues to identify overimmunosuppressed kidney transplant recipients (KTR) who would subsequently develop CMV infection...
  11. doi request reprint Variability and recombination of clinical human cytomegalovirus strains from transplantation recipients
    Muriel Faure-Della Corte
    PRES Université de Bordeaux, Laboratoire de Virologie EA2968 and IFR66, 33076 Bordeaux, France
    J Clin Virol 47:161-9. 2010
    ..Human cytomegalovirus (HCMV) is the first cause of viral infection in immunocompromised transplanted patients...
  12. pmc Long-term expansion of effector/memory Vdelta2-gammadelta T cells is a specific blood signature of CMV infection
    Vincent Pitard
    Universite Bordeaux 2, Bordeaux, France
    Blood 112:1317-24. 2008
    ..In conclusion, the increased level of effector-memory Vdelta2- gammadelta T cells in the peripheral blood is a specific signature of an adaptive immune response to CMV infection of both immunocompetent and immunosuppressed patients...
  13. pmc Cytomegalovirus-induced gammadelta T cells associate with reduced cancer risk after kidney transplantation
    Lionel Couzi
    Centre National de la Recherche Scientifique Unite Mixte de Recherche 5164, Universite Victor Segalen Bordeaux 2, Bordeaux, France
    J Am Soc Nephrol 21:181-8. 2010
    ..In summary, these results suggest a protective role of CMV exposure against cancer in kidney transplant recipients...
  14. doi request reprint The complement interference phenomenon as a cause for sharp fluctuations of serum anti-HLA antibody strength in kidney transplant patients
    Gwendaline Guidicelli
    Laboratoire d Immunologie et Immunogénétique, Hopital Pellegrin, CHU de Bordeaux, Bordeaux, France Electronic address
    Transpl Immunol 29:17-21. 2013
    ..A prospective pre-transplant crossmatch still remains an ultimate safeguard...
  15. doi request reprint Long-term outcome on renal replacement therapy in patients who previously received a keto acid-supplemented very-low-protein diet
    Philippe Chauveau
    Department of Nephrology, Centre Hospitalier Universitaire and University Bordeaux II, Bordeaux, France
    Am J Clin Nutr 90:969-74. 2009
    ..The consequences of a supplemented very-low-protein diet remain a matter of debate with regard to patient outcome before or after the onset of renal replacement therapy...
  16. doi request reprint Laparoscopic radical prostatectomy in renal transplant recipients
    Gregoire Robert
    Department of Urology, Bordeaux University Hospital, Bordeaux, France
    Urology 74:683-7. 2009
    ..Retropubic radical prostatectomy has widely been described in RTR, whereas LRP has rarely been studied...
  17. ncbi request reprint Variability of UL18, UL40, UL111a and US3 immunomodulatory genes among human cytomegalovirus clinical isolates from renal transplant recipients
    Isabelle Garrigue
    Universite Bordeaux 2, Laboratoire de Virologie EA2968 and IFR66, 146 rue Leo Saignat, 33 076, Bordeaux Cedex, France
    J Clin Virol 40:120-8. 2007
    ..Variability of human cytomegalovirus (HCMV) genes counteracting immune responses is poorly investigated in non-cultured clinical strains...
  18. pmc Prediction of cytomegalovirus (CMV) plasma load from evaluation of CMV whole-blood load in samples from renal transplant recipients
    Isabelle Garrigue
    Universite Victor Segalen Bordeaux 2, Laboratoire de Virologie EA2968, 146 rue Leo Saignat, 33 076 Bordeaux Cedex, France
    J Clin Microbiol 46:493-8. 2008
    ..WB seems to be an appropriate candidate for routine CMV monitoring of transplant recipients by using a single assay...
  19. doi request reprint [Analysis of hemodialysis and graft representations in patients with chronic renal failure: an anthropological approach]
    Aurélie Desseix
    EA2963, laboratoire d ethnologie Anthropologie des traditions orales et du temps, Universite Victor Segalen Bordeaux 2, 3, ter Place de la Victoire, 33076 Bordeaux Cedex, France
    Nephrol Ther 6:111-20. 2010
    ....
  20. doi request reprint UL40 human cytomegalovirus variability evolution patterns over time in renal transplant recipients
    Isabelle Garrigue
    Universite Bordeaux 2, Laboratoire de Virologie EA2968 and IFR66, F 33 076 Bordeaux, France
    Transplantation 86:826-35. 2008
    ..One of HCMV immunomodulatory genes, UL40, confers HCMV-infected cells' protection from natural killer-mediated lysis through its encoded nonapeptide presented in the context of human leukocyte antigen-E...
  21. ncbi request reprint New molecular assays to predict occurrence of cytomegalovirus disease in renal transplant recipients
    I Pellegrin
    Laboratoire de Virologie, Centre Hospitalier Régional Hôpital Pellegrin, Place Amelie Raba Leon, 33 076 Bordeaux Cedex, France
    J Infect Dis 182:36-42. 2000
    ..PBL assays appear to be more appropriate than plasma assays when pre-emptive therapy is required to prevent the rapid progression from the first detection of the virus to CMV disease...
  22. doi request reprint Inherited deficiency of membrane cofactor protein expression and varying manifestations of recurrent atypical hemolytic uremic syndrome in a sibling pair
    Lionel Couzi
    CHU Bordeaux, Hopital Pellegrin, Bordeaux, France
    Am J Kidney Dis 52:e5-9. 2008
    ..In conclusion, we describe for the first time a disease-free individual with complete CD46 deficiency, confirming the extremely variable penetrance and genetic complexity of aHUS...
  23. ncbi request reprint An atypical necrotic signal induced by immunosuppressive and anti-viral agents
    Benjamin Chaigne-Delalande
    Universite de Bordeaux 2, CNRS UMR 5164 and IFR66, 146 rue Leo Saignat, Bordeaux, France
    Autophagy 5:425-7. 2009
    ....
  24. ncbi request reprint Predominance of CD8+ T lymphocytes among periglomerular infiltrating cells and link to the prognosis of class III and class IV lupus nephritis
    Lionel Couzi
    CHU, and UMR CNRS 5164, Universite Victor Segalen Bordeaux 2, Bordeaux, France
    Arthritis Rheum 56:2362-70. 2007
    ..The aim of the present study was to analyze the localization of CD8+ cells in the kidneys of patients with class III and class IV lupus nephritis and to establish correlations with histologic, biologic, and clinical features of SLE...
  25. ncbi request reprint Verapamil and mild hyperkalemia in hemodialysis patients: a potentially hazardous association
    Emmanuel Letavernier
    Service de Néphrologie et d Hémodialyse, CHU Pellegrin, Bordeaux, France
    Hemodial Int 10:170-2. 2006
    ..The medical history of these patients revealed no intrinsic cause of atrioventricular conduction disturbance. We report herein the 3 cases and draw attention to the risks of atrioventricular block in this particular context...
  26. ncbi request reprint Whole blood real-time quantitative PCR for cytomegalovirus infection follow-up in transplant recipients
    Isabelle Garrigue
    Département de Virologie et d Immunologie Biologique and Laboratoire EA 2968, Centre Hospitalo Universitaire de Bordeaux, 33076 Bordeaux, France
    J Clin Virol 36:72-5. 2006
    ..However, correlations are lacking between results of pp65Ag and quantitative PCR assays and there is no consensus yet as to the more appropriate blood compartment (whole blood (WB), leukocytes, plasma) to be tested with PCR assays...
  27. doi request reprint Quantitative elastography of renal transplants using supersonic shear imaging: a pilot study
    Nicolas Grenier
    Service d Imagerie Diagnostique et Interventionnelle de l Adulte, Centre Hospitalier Universitaire de Bordeaux, Université Bordeaux Segalen, 33076, Bordeaux, France
    Eur Radiol 22:2138-46. 2012
    ..To evaluate the reliability of quantitative ultrasonic measurement of renal allograft elasticity using supersonic shear imaging (SSI) and its relationship with parenchymal pathological changes...