Jean Michel Constantin

Summary

Affiliation: CHU de Clermont-Ferrand
Country: France

Publications

  1. doi request reprint Lung morphology predicts response to recruitment maneuver in patients with acute respiratory distress syndrome
    Jean Michel Constantin
    Department of Anesthesiology and Critical Care Medicine, Surgical Intensive Care Unit EF, Department of Anesthesiology and Critical Care Medicine, Surgical Intensive Care Unit, Hotel Dieu Hospital, University Hospital of Clermont Ferrand, Clermont Ferrand, France
    Crit Care Med 38:1108-17. 2010
  2. pmc Fluid management and risk factors for renal dysfunction in patients with severe sepsis and/or septic shock
    Laurent Muller
    Division Anesthésie Réanimation Douleur Urgences, CHU de Nimes, place du Professeur Robert Debré, 30029 Nimes Cedex 9, France
    Crit Care 16:R34. 2012
  3. ncbi request reprint Lung imaging in patients with acute respiratory distress syndrome: from an understanding of pathophysiology to bedside monitoring
    J M Constantin
    Department of Anesthesiology and Critical Care Medicine, Estaing University Hospital, Clermont Ferrand, France
    Minerva Anestesiol 79:176-84. 2013
  4. pmc Positive end-expiratory pressure affects the value of intra-abdominal pressure in acute lung injury/acute respiratory distress syndrome patients: a pilot study
    Daniel Verzilli
    Intensive Care and Transplantation Unit, Department of Anaesthesiology and Critical Care, University Saint Eloi Hospital, 80 avenue Augustin Fliche, University of Montpellier I, F 34295 Montpellier cedex 5, France
    Crit Care 14:R137. 2010
  5. pmc How the relationships between general practitioners and intensivists can be improved: the general practitioners' point of view
    Bérengère Etesse
    Division Anesthésie Réanimation Douleur Urgences, Groupe Hospitalo Universitaire Caremeau, Centre Hospitalier Universitaire Nîmes, place du Professeur Robert Debré, 30029 Nimes Cedex 9, France
    Crit Care 14:R112. 2010
  6. pmc A recruitment maneuver increases oxygenation after intubation of hypoxemic intensive care unit patients: a randomized controlled study
    Jean Michel Constantin
    General ICU, Department of Anesthesiology and Critical Care, Estaing Hospital, University Hospital of Clermont Ferrand, 1 Place Lucie Aubrac, Clermont Ferrand, France
    Crit Care 14:R76. 2010
  7. doi request reprint Plasma neutrophil gelatinase-associated lipocalin is an early marker of acute kidney injury in adult critically ill patients: a prospective study
    Jean Michel Constantin
    Surgical Intensive Care Unit, Department of Anesthesiology and Critical Care Medicine, Hotel Dieu Hospital, University Hospital of Clermont Ferrand, Clermont Ferrand, France
    J Crit Care 25:176.e1-6. 2010
  8. doi request reprint [Tolerance of caspofungin in intensive care unit: a prospective study]
    J M Constantin
    Pole Anesthésie Réanimation, Service de Reanimation Adulte, Hopital Hotel Dieu, CHU de Clermont Ferrand, Boulevard Leon Malfreyt, 63058 Clermont Ferrand, France
    Ann Fr Anesth Reanim 27:819-24. 2008
  9. ncbi request reprint Response to recruitment maneuver influences net alveolar fluid clearance in acute respiratory distress syndrome
    Jean Michel Constantin
    Surgical Intensive Care Unit, Department of Anesthesiology, Hotel Dieu Hospital, University Hospital of Clermont Ferrand, INSERM U384, Clermont Ferrand, France
    Anesthesiology 106:944-51. 2007
  10. pmc Respiratory effects of different recruitment maneuvers in acute respiratory distress syndrome
    Jean Michel Constantin
    General Intensive Care Unit, Hotel Dieu Hospital, University Hospital of Clermont Ferrand, Boulevard L, Malfreyt, 63058 Clermond Ferrand, France
    Crit Care 12:R50. 2008

Collaborators

Detail Information

Publications36

  1. doi request reprint Lung morphology predicts response to recruitment maneuver in patients with acute respiratory distress syndrome
    Jean Michel Constantin
    Department of Anesthesiology and Critical Care Medicine, Surgical Intensive Care Unit EF, Department of Anesthesiology and Critical Care Medicine, Surgical Intensive Care Unit, Hotel Dieu Hospital, University Hospital of Clermont Ferrand, Clermont Ferrand, France
    Crit Care Med 38:1108-17. 2010
    ..The objective was to determine whether differences in lung morphology, defined as differences in the pulmonary distribution of aeration loss, predict the response to recruitment maneuvers...
  2. pmc Fluid management and risk factors for renal dysfunction in patients with severe sepsis and/or septic shock
    Laurent Muller
    Division Anesthésie Réanimation Douleur Urgences, CHU de Nimes, place du Professeur Robert Debré, 30029 Nimes Cedex 9, France
    Crit Care 16:R34. 2012
    ..Using the database of a multicenter study focusing on patients with severe sepsis and septic shock, the present study aimed at identifying factors associated with the occurrence of renal dysfunction...
  3. ncbi request reprint Lung imaging in patients with acute respiratory distress syndrome: from an understanding of pathophysiology to bedside monitoring
    J M Constantin
    Department of Anesthesiology and Critical Care Medicine, Estaing University Hospital, Clermont Ferrand, France
    Minerva Anestesiol 79:176-84. 2013
    ..The aim of the present review is to consider how lung imaging has facilitated the evolution of knowledge of this syndrome, and to place such knowledge in a clinical perspective...
  4. pmc Positive end-expiratory pressure affects the value of intra-abdominal pressure in acute lung injury/acute respiratory distress syndrome patients: a pilot study
    Daniel Verzilli
    Intensive Care and Transplantation Unit, Department of Anaesthesiology and Critical Care, University Saint Eloi Hospital, 80 avenue Augustin Fliche, University of Montpellier I, F 34295 Montpellier cedex 5, France
    Crit Care 14:R137. 2010
    ..To examine the effects of positive end-expiratory pressure (PEEP) on intra-abdominal pressure (IAP) in patients with acute lung injury (ALI)...
  5. pmc How the relationships between general practitioners and intensivists can be improved: the general practitioners' point of view
    Bérengère Etesse
    Division Anesthésie Réanimation Douleur Urgences, Groupe Hospitalo Universitaire Caremeau, Centre Hospitalier Universitaire Nîmes, place du Professeur Robert Debré, 30029 Nimes Cedex 9, France
    Crit Care 14:R112. 2010
    ..The present study assessed the opinion of general practitioners (GPs) concerning their relationships with intensivists...
  6. pmc A recruitment maneuver increases oxygenation after intubation of hypoxemic intensive care unit patients: a randomized controlled study
    Jean Michel Constantin
    General ICU, Department of Anesthesiology and Critical Care, Estaing Hospital, University Hospital of Clermont Ferrand, 1 Place Lucie Aubrac, Clermont Ferrand, France
    Crit Care 14:R76. 2010
    ..In acute lung injury patients, recruitment maneuvers (RMs) increase lung volume and oxygenation, and decrease atelectasis. The aim of this study was to evaluate the efficacy and safety of RMs performed immediately after intubation...
  7. doi request reprint Plasma neutrophil gelatinase-associated lipocalin is an early marker of acute kidney injury in adult critically ill patients: a prospective study
    Jean Michel Constantin
    Surgical Intensive Care Unit, Department of Anesthesiology and Critical Care Medicine, Hotel Dieu Hospital, University Hospital of Clermont Ferrand, Clermont Ferrand, France
    J Crit Care 25:176.e1-6. 2010
    ..The aim of the study was to assess the ability of plasma neutrophil gelatinase-associated lipocalin (pNGAL) to predict acute kidney injury (AKI) in adult intensive care unit (ICU) patients...
  8. doi request reprint [Tolerance of caspofungin in intensive care unit: a prospective study]
    J M Constantin
    Pole Anesthésie Réanimation, Service de Reanimation Adulte, Hopital Hotel Dieu, CHU de Clermont Ferrand, Boulevard Leon Malfreyt, 63058 Clermont Ferrand, France
    Ann Fr Anesth Reanim 27:819-24. 2008
    ..To date, there is no data on tolerability of caspofungin in ICU patients. The aim of this study was to evaluate caspofungine tolerability in critical care patients...
  9. ncbi request reprint Response to recruitment maneuver influences net alveolar fluid clearance in acute respiratory distress syndrome
    Jean Michel Constantin
    Surgical Intensive Care Unit, Department of Anesthesiology, Hotel Dieu Hospital, University Hospital of Clermont Ferrand, INSERM U384, Clermont Ferrand, France
    Anesthesiology 106:944-51. 2007
    ..Experimental studies have shown that a reduction of tidal volume increases alveolar fluid clearance. This study was aimed at assessing the impact of the response to a recruitment maneuver (RM) on net alveolar fluid clearance...
  10. pmc Respiratory effects of different recruitment maneuvers in acute respiratory distress syndrome
    Jean Michel Constantin
    General Intensive Care Unit, Hotel Dieu Hospital, University Hospital of Clermont Ferrand, Boulevard L, Malfreyt, 63058 Clermond Ferrand, France
    Crit Care 12:R50. 2008
    ..Alveolar derecruitment may occur during low tidal volume ventilation and may be prevented by recruitment maneuvers (RMs). The aim of this study was to compare two RMs in acute respiratory distress syndrome (ARDS) patients...
  11. pmc Lemierre's syndrome and genetic polymorphisms: a case report
    Jean Michel Constantin
    Adult Intensive Care Unit, Department of Anesthesiology and Intensive Care, University Hospital of Clermont Ferrand, Hotel Dieu Hospital, F 63058 Clermont Ferrand, France
    BMC Infect Dis 6:115. 2006
    ..Lemierre's syndrome presents a classic clinical picture, the pathophysiology of which remains obscure. Attempts have been made to trace genetic predispositions that modify the host detection of pathogen or the resultant systemic reaction...
  12. ncbi request reprint Remifentanil-based sedation to treat noninvasive ventilation failure: a preliminary study
    Jean Michel Constantin
    CHU Clermont Ferrand, Service de Reanimation Adulte, Hotel Dieu Hospital, 63058, Clermont Ferrand, France
    Intensive Care Med 33:82-7. 2007
    ..To assess the feasibility and safety of remifentanil-based sedation during noninvasive ventilation (NIV) in patients with NIV failure...
  13. pmc Plasma levels of sRAGE, loss of aeration and weaning failure in ICU patients: a prospective observational multicenter study
    Matthieu Jabaudon
    Intensive Care Unit, Department of Anesthesiology and Critical Care Medicine, Estaing Hospital, CHU Clermont Ferrand, Université d Auvergne Clermont Ferrand 1, Clermont Ferrand, France
    PLoS ONE 8:e64083. 2013
    ..Lung ultrasound determination of changes in lung aeration predicts weaning failure. It remains unknown whether this derecruitment is related to alveolar epithelial dysfunction or not...
  14. doi request reprint Conservative vs restrictive individualized goal-directed fluid replacement strategy in major abdominal surgery: A prospective randomized trial
    Emmanuel Futier
    Department of Anesthesiology and Critical Care, University Hospital of Clermont Ferrand, France
    Arch Surg 145:1193-200. 2010
    ....
  15. doi request reprint Soluble form of the receptor for advanced glycation end products is a marker of acute lung injury but not of severe sepsis in critically ill patients
    Matthieu Jabaudon
    Department of Anesthesiology and Critical Care Medicine, Intensive Care Unit, Estaing University Hospital, CHU Clermont Ferrand, Clermont Ferrand, France
    Crit Care Med 39:480-8. 2011
    ..Whether sRAGE is a marker of acute lung injury and acute respiratory distress syndrome, regardless of associated severe sepsis or septic shock, remains unknown in the intensive care unit setting...
  16. doi request reprint Noninvasive ventilation and alveolar recruitment maneuver improve respiratory function during and after intubation of morbidly obese patients: a randomized controlled study
    Emmanuel Futier
    Department of Anesthesiology and Critical Care Medicine, Estaing Hospital, University Hospital of Clermont Ferrand, Clermont Ferrand, France
    Anesthesiology 114:1354-63. 2011
    ....
  17. doi request reprint Intraoperative recruitment maneuver reverses detrimental pneumoperitoneum-induced respiratory effects in healthy weight and obese patients undergoing laparoscopy
    Emmanuel Futier
    Department of Anesthesiology and Critical Care Medicine, Estaing Hospital, Clermont Ferrand, France
    Anesthesiology 113:1310-9. 2010
    ....
  18. pmc Central venous O₂ saturation and venous-to-arterial CO₂ difference as complementary tools for goal-directed therapy during high-risk surgery
    Emmanuel Futier
    Department of Anaesthesiology and Critical Care Medicine, Estaing Hospital, University Hospital of Clermont Ferrand, 1 Place Lucie Aubrac, Clermont Ferrand, 63000, France
    Crit Care 14:R193. 2010
    ....
  19. pmc Measurement of alveolar derecruitment in patients with acute lung injury: computerized tomography versus pressure-volume curve
    Qin Lu
    Surgical Intensive Care Unit Pierre Viars, Department of Anesthesiology, Assistance Publique Hopitaux de Paris, La Pitie Salpetriere Hospital, 47 83 Boulevard de l Hôpital 75013 Paris, France
    Crit Care 10:R95. 2006
    ..The aim of the study was to compare both methods for assessing alveolar derecruitment after the removal of PEEP in patients with acute lung injury or acute respiratory distress syndrome...
  20. pmc Pressure support ventilation attenuates ventilator-induced protein modifications in the diaphragm
    Emmanuel Futier
    General Intensive Care Unit, Hotel Dieu Hospital, University Hospital of Clermont Ferrand, Boulevard L Malfreyt, Clermond Ferrand, 63058, France
    Crit Care 12:R116. 2008
    ..We hypothesized that mechanical ventilation in pressure support ventilation (PSV), which preserves diaphragm muscle activity, would limit diaphragmatic protein catabolism...
  21. ncbi request reprint Adaptive support ventilation prevents ventilator-induced diaphragmatic dysfunction in piglet: an in vivo and in vitro study
    Boris Jung
    Department of Anesthesiology and Critical Care, Intensive Care Unit, Saint Eloi Teaching Hospital, Equipe soutenue par la Région et l Institut National de la Santé et de la Recherche Médicale 25, Centre Hospitalier Universitaire Montpellier, Montpellier, France
    Anesthesiology 112:1435-43. 2010
    ..The aim of our study was to compare the effects of ASV with those of CMV on both in vivo and in vitro diaphragmatic properties...
  22. doi request reprint A trial of intraoperative low-tidal-volume ventilation in abdominal surgery
    Emmanuel Futier
    Département d anesthésie et réanimation, hôpital Estaing, Clermont Ferrand, France
    N Engl J Med 369:428-37. 2013
    ..However, its role in anesthetized patients undergoing major surgery is not known...
  23. pmc Refeeding syndrome influences outcome of anorexia nervosa patients in intensive care unit: an observational study
    Marie Vignaud
    General ICU, Estaing Hospital, University Hospital of Clermont Ferrand, 1 Place Lucie Aubrac, 63000 Clermont Ferrand, France
    Crit Care 14:R172. 2010
    ..Data on the epidemiology and management of anorexia nervosa (AN) in the intensive care unit (ICU) are scarce. The aim of this study was to evaluate the prevalence and associated morbidity and mortality of AN in French ICUs...
  24. doi request reprint Positive end-expiratory pressure improves end-expiratory lung volume but not oxygenation after induction of anaesthesia
    Emmanuel Futier
    Department of Anaesthesiology and Critical Care, Hotel Dieu Hospital, University Hospital of Clermont Ferrand, Clermont Ferrand, France
    Eur J Anaesthesiol 27:508-13. 2010
    ..We hypothesized that end-expiratory lung volume (EELV) may be more sensitive than oxygenation to evaluate the effects of positive end-expiratory pressure (PEEP) after anaesthesia induction...
  25. ncbi request reprint Rapid onset of specific diaphragm weakness in a healthy murine model of ventilator-induced diaphragmatic dysfunction
    Segolene Mrozek
    Department of Anesthesiology and Critical Care, Clermont Ferrand University Hospital, Montpellier, France
    Anesthesiology 117:560-7. 2012
    ....
  26. doi request reprint [Non-invasive ventilation for pulmonary edema associated with tocolytic agents during labour for a twin pregnancy]
    Sebastien Perbet
    Département d anesthésie et de réanimation, Hotel Dieu, centre hospitalier universitaire de Clermont Ferrand, Boulevard Leon Malfreyt, 63058 Clermont Ferrand Cedex 1, France
    Can J Anaesth 55:769-73. 2008
    ..To describe the efficacy and patient acceptance of non-invasive ventilation for pulmonary edema associated with administration of tocolytic drugs during labour of a twin pregnancy...
  27. ncbi request reprint Epidemiology and outcome of thrombocytopenic patients in the intensive care unit: results of a prospective multicenter study
    Fabrice Thiollière
    Service de Reanimation Medicale, Hopital Gabriel Montpied, CHU de Clermont Ferrand, BP69, 63003, Clermont Ferrand cedex 01, France
    Intensive Care Med 39:1460-8. 2013
    ..To assess the epidemiology of intensive care unit (ICU) patients with thrombocytopenia (TP)...
  28. pmc The OPERA trial - comparison of early nasal high flow oxygen therapy with standard care for prevention of postoperative hypoxemia after abdominal surgery: study protocol for a multicenter randomized controlled trial
    Emmanuel Futier
    Department of Anesthesiology and Critical Care Medicine, Estaing Hospital, University Teaching Hospital of Clermont Ferrand, 1, place Lucie Aubrac, Clermont Ferrand Cedex 1, 63000, France
    Trials 14:341. 2013
    ..Whether application of HFNC may have therapeutic advantages over conventional oxygen therapy for respiratory support in the early postextubation surgical period remains to be established...
  29. ncbi request reprint Neurally adjusted ventilatory assist vs pressure support ventilation for noninvasive ventilation during acute respiratory failure: a crossover physiologic study
    Pierre Marie Bertrand
    Department of Anesthesiology and Critical Care, Estaing Hospital, University Hospital of Clermont Ferrand, Clermont Ferrand, France
    Chest 143:30-6. 2013
    ..We examined the effect of neurally adjusted ventilatory assist (NAVA) delivered through a facemask on synchronization in patients with acute respiratory failure (ARF)...
  30. ncbi request reprint Epidural versus continuous preperitoneal analgesia during fast-track open colorectal surgery: a randomized controlled trial
    Philippe Jouve
    Department of Anesthesiology and Critical Care Medicine, Estaing Hospital, University Hospital of Clermont Ferrand, Clermont Ferrand, France
    Anesthesiology 118:622-30. 2013
    ..This prospective, double-blind trial compared CWI and EA in patients undergoing elective open colorectal surgery...
  31. doi request reprint Ultrasound assessment of lung aeration loss during a successful weaning trial predicts postextubation distress*
    Alexis Soummer
    Department of Anesthesiology and Critical Care Medicine, Multidisciplinary Intensive Care Unit, Pierre Viars, La Pitie Salpetriere Hospital, Assistance Publique Hopitaux de Paris, UPMC Univ, Paris, France
    Crit Care Med 40:2064-72. 2012
    ..Predicting postextubation distress is therefore a major issue in critically ill patients. To assess whether lung derecruitment during spontaneous breathing trial assessed by lung ultrasound is predictive of postextubation distress...
  32. ncbi request reprint Guidance and examination by ultrasound versus landmark and radiographic method for placement of subclavian central venous catheters: study protocol for a randomized controlled trial
    Sebastien Perbet
    Department of Anesthesiology and Critical Care Medicine, CHU Estaing, CHU Clermont Ferrand, Intensive Care Unit, F 63000 Clermont Ferrand, France
    Trials 15:175. 2014
    ..It is unclear, however, whether ultrasound real-time guidance and examination can reduce procedure times and complication rates when compared with landmark guidance and radiographic examination for SCV catheterization...
  33. doi request reprint Comparison of acceptability, skin tolerance, and compliance between handwashing and alcohol-based handrub in ICUs: results of a multicentric study
    Bertrand Souweine
    CHU Clermont Ferrand, Unite de Reanimation Medicale, Pole REUNNIRH, Hop G Montpied, 63003, Clermont Ferrand, France
    Intensive Care Med 35:1216-24. 2009
    ..We compared handwashing (HW) and alcohol-based handrub (ABH) for skin tolerance, acceptability, and hand hygiene compliance in health-care workers (HCWs) in a multicentric study...
  34. doi request reprint Simple assay of plasma sevoflurane and its metabolite hexafluoroisopropanol by headspace GC-MS
    Daniel Bourdeaux
    CHU Clermont Ferrand, Department of Pharmacy, Hop G Montpied, F 63003 Clermont Ferrand, France
    J Chromatogr B Analyt Technol Biomed Life Sci 878:45-50. 2010
    ..Average sevoflurane and HFIP concentrations plateaued at 75 and 4microg/ml, respectively. Sevoflurane quickly tailed off after inhalation was stopped, and HFIP levels remained low...
  35. pmc TEM-158 (CMT-9), a new member of the CMT-type extended-spectrum beta-lactamases
    Frederic Robin
    CHU Clermont Ferrand, Centre de Biologie, Laboratoire de bactériologiecinique, Faculte de Medecine, 28 place H Dunant, 63001 Clermont Ferrand, France
    Antimicrob Agents Chemother 51:4181-3. 2007
    ..This enzyme presented hydrolytic activity against ceftazidime and a high level of resistance against clavulanate, which can alter its detection. Its discovery highlights the need for accurate detection methods...
  36. ncbi request reprint Mechanical ventilation in patients with acute respiratory distress syndrome
    Jean Jacques Rouby
    Praticien Hospitalier, Surgical Intensive Care Unit Pierre Viars, Research Coordinator, La Pitie Salpetriere Hospital, France
    Anesthesiology 101:228-34. 2004