Paulette Bioulac-Sage

Summary

Affiliation: CHU de Bordeaux
Country: France

Publications

  1. pmc Pathological Diagnosis of Hepatocellular Cellular Adenoma according to the Clinical Context
    Paulette Bioulac-Sage
    Service d Anatomie Pathologique, Hopital Pellegrin, CHU Bordeaux, 33076 Bordeaux, France U1053 Université Bordeaux 2, 33076 Bordeaux, France
    Int J Hepatol 2013:253261. 2013
  2. doi Immunohistochemical markers on needle biopsies are helpful for the diagnosis of focal nodular hyperplasia and hepatocellular adenoma subtypes
    Paulette Bioulac-Sage
    Department of Pathology, CHU Bordeaux, Hopital Pellegrin, Bordeaux, France
    Am J Surg Pathol 36:1691-9. 2012
  3. doi Hepatocellular adenoma subtypes: the impact of overweight and obesity
    Paulette Bioulac-Sage
    Service d Anatomie Pathologique, Hopital Pellegrin, CHU Bordeaux, Bordeaux, France
    Liver Int 32:1217-21. 2012
  4. pmc Immunohistochemical study of the phenotypic change of the mesenchymal cells during portal tract maturation in normal and fibrous (ductal plate malformation) fetal liver
    Julien Villeneuve
    INSERM U889, , F 33076 Bordeaux, France
    Comp Hepatol 8:5. 2009
  5. pmc HNF1α inhibition triggers epithelial-mesenchymal transition in human liver cancer cell lines
    Laura Pelletier
    Inserm U674 Génomique fonctionnelle des tumeurs solides, Paris, France
    BMC Cancer 11:427. 2011
  6. doi Hepatic resection for inflammatory hepatocellular adenomas: pathological identification of micronodules expressing inflammatory proteins
    Paulette Bioulac-Sage
    Department of Pathology, CHU de Bordeaux, Hopital Pellegrin, Bordeaux, France
    Liver Int 30:149-54. 2010
  7. pmc Hepatocellular adenoma: what is new in 2008
    Paulette Bioulac-Sage
    Department of Pathology, Hôpital Pellegrin CHU Bordeaux, Universite Bordeaux 2, Inserm 889, Bordeaux Cedex, France
    Hepatol Int 2:316-21. 2008
  8. ncbi Hepatocellular adenoma management and phenotypic classification: the Bordeaux experience
    Paulette Bioulac-Sage
    Service d Anatomie Pathologique, Hopital Pellegrin, Centre Hospitalier Universitaire Bordeaux, Bordeaux, France
    Hepatology 50:481-9. 2009
  9. doi Over-expression of glutamine synthetase in focal nodular hyperplasia: a novel easy diagnostic tool in surgical pathology
    Paulette Bioulac-Sage
    Department of Pathology, Hôpital Pellegrin CHU Bordeaux, Bordeaux, France
    Liver Int 29:459-65. 2009
  10. doi Subtype classification of hepatocellular adenoma
    Paulette Bioulac-Sage
    Service d Anatomie Pathologique, Hopital Pellegrin, CHU Bordeaux, France
    Dig Surg 27:39-45. 2010

Detail Information

Publications59

  1. pmc Pathological Diagnosis of Hepatocellular Cellular Adenoma according to the Clinical Context
    Paulette Bioulac-Sage
    Service d Anatomie Pathologique, Hopital Pellegrin, CHU Bordeaux, 33076 Bordeaux, France U1053 Université Bordeaux 2, 33076 Bordeaux, France
    Int J Hepatol 2013:253261. 2013
    ..When the whole nodule is a hepatocellular carcinoma, it is extremely difficult to prove that it is the consequence of a former HCA. It is occasionally difficult to identify HCA remodeled by necrosis or hemorrhage...
  2. doi Immunohistochemical markers on needle biopsies are helpful for the diagnosis of focal nodular hyperplasia and hepatocellular adenoma subtypes
    Paulette Bioulac-Sage
    Department of Pathology, CHU Bordeaux, Hopital Pellegrin, Bordeaux, France
    Am J Surg Pathol 36:1691-9. 2012
    ..714) or for HCA subtypes (P=0.750). Compared with surgical specimens, immunohistochemical analysis performed on biopsies allowed the discrimination of FNH from HCA and the identification of HCA subtypes with good performance...
  3. doi Hepatocellular adenoma subtypes: the impact of overweight and obesity
    Paulette Bioulac-Sage
    Service d Anatomie Pathologique, Hopital Pellegrin, CHU Bordeaux, Bordeaux, France
    Liver Int 32:1217-21. 2012
    ..With the appearance of a generation of new oral contraceptives, the number of HCA cases was anticipated to decrease, but in fact this was not observed in our practice. The influence of obesity was therefore suspected as a new co-factor...
  4. pmc Immunohistochemical study of the phenotypic change of the mesenchymal cells during portal tract maturation in normal and fibrous (ductal plate malformation) fetal liver
    Julien Villeneuve
    INSERM U889, , F 33076 Bordeaux, France
    Comp Hepatol 8:5. 2009
    ..During portal tract maturation, myofibroblastic cells disappear in normal development but persist in fibrosis following ductal plate malformation...
  5. pmc HNF1α inhibition triggers epithelial-mesenchymal transition in human liver cancer cell lines
    Laura Pelletier
    Inserm U674 Génomique fonctionnelle des tumeurs solides, Paris, France
    BMC Cancer 11:427. 2011
    ..We studied the consequences of HNF1α silencing in hepatic cell lines, HepG2 and Hep3B and we reproduced most of the deregulations identified in H-HCA...
  6. doi Hepatic resection for inflammatory hepatocellular adenomas: pathological identification of micronodules expressing inflammatory proteins
    Paulette Bioulac-Sage
    Department of Pathology, CHU de Bordeaux, Hopital Pellegrin, Bordeaux, France
    Liver Int 30:149-54. 2010
    ..Frequently, additional micronodules (<10 mm), previously undetected by imaging, can be observed in resected specimens...
  7. pmc Hepatocellular adenoma: what is new in 2008
    Paulette Bioulac-Sage
    Department of Pathology, Hôpital Pellegrin CHU Bordeaux, Universite Bordeaux 2, Inserm 889, Bordeaux Cedex, France
    Hepatol Int 2:316-21. 2008
    ....
  8. ncbi Hepatocellular adenoma management and phenotypic classification: the Bordeaux experience
    Paulette Bioulac-Sage
    Service d Anatomie Pathologique, Hopital Pellegrin, Centre Hospitalier Universitaire Bordeaux, Bordeaux, France
    Hepatology 50:481-9. 2009
    ..Six patients of 128 developed hepatocellular carcinoma (HCC) (all were beta-catenin-activated, whether inflammatory or not)...
  9. doi Over-expression of glutamine synthetase in focal nodular hyperplasia: a novel easy diagnostic tool in surgical pathology
    Paulette Bioulac-Sage
    Department of Pathology, Hôpital Pellegrin CHU Bordeaux, Bordeaux, France
    Liver Int 29:459-65. 2009
    ..We investigated the use of GS as a marker in various clinical situations, in which FNH diagnosis had been firmly established to determine its contribution to diagnosis...
  10. doi Subtype classification of hepatocellular adenoma
    Paulette Bioulac-Sage
    Service d Anatomie Pathologique, Hopital Pellegrin, CHU Bordeaux, France
    Dig Surg 27:39-45. 2010
    ..Taking into account noticeable differences between the HCA subgroups, in terms of clinical and prognostic features, phenotyping may become an important tool for HCA management strategy...
  11. doi [Interest of immunohistochemistry for the diagnosis of benign hepatocellular tumors]
    Paulette Bioulac-Sage
    Hopital Pellegrin, CHU de Bordeaux, France
    Ann Pathol 30:439-47. 2010
    ..Immunohistochemical characteristics described on resected specimen are suitable on biopies of these tumors, facilitating their diagnosis and therefore allowing a better management of the patients...
  12. doi Benign and malignant vascular tumors of the liver in adults
    Paulette Bioulac-Sage
    Department of Pathology, Hopital Pellegrin, CHU Bordeaux, France
    Semin Liver Dis 28:302-14. 2008
    ..The prognosis of angiosarcoma remains dismal. Designing a worldwide database that contains all data about patients with these rare diseases is recommended...
  13. doi Perinodular CK19 loss in hepatocarcinogenesis
    Paulette Bioulac-Sage
    GREF Inserm U1053, Service d Anatomie Pathologique, Hopital Pellegrin, CHU de Bordeaux, Université Bordeaux Segalen, 33076 Bordeaux Cedex, France
    Clin Res Hepatol Gastroenterol 35:783-5. 2011
    ..Paracrine signalling is proposed as a link that emphasizes the importance of the epithelial-stromal compartment in malignant progression of HCC in cirrhosis...
  14. doi Revisiting the pathology of resected benign hepatocellular nodules using new immunohistochemical markers
    Paulette Bioulac-Sage
    Service d Anatomie Pathologique, Hopital Pellegrin, CHU Bordeaux, Bordeaux cedex France
    Semin Liver Dis 31:91-103. 2011
    ..IHCA can also be β-catenin activated (10%). Due to the strong association of b-HCA with hepatocellular carcinoma transformation, the identification of this HCA subtype is extremely important...
  15. ncbi Clinical, morphologic, and molecular features defining so-called telangiectatic focal nodular hyperplasias of the liver
    Paulette Bioulac-Sage
    Department of Pathology, Centre Hospitalier Universitaire de Bordeaux, France
    Gastroenterology 128:1211-8. 2005
    ..The aim of this study was to use molecular markers, in addition to morphologic features, to better characterize TFNH...
  16. pmc Smoothelin, a new marker to determine the origin of liver fibrogenic cells
    Sebastien Lepreux
    Sébastien Lepreux, CHU Bordeaux, Hopital Pellegrin, Service d Anatomie Pathologique, F 33076 Bordeaux, France
    World J Gastroenterol 19:9343-50. 2013
    ..To explore this hypothesis that smooth muscle cells may be capable of acquiring a myofibroblastic phenotype, we have studied the expression of smoothelin in fibrotic conditions...
  17. ncbi The identification of small nodules in liver adenomatosis
    Sebastien Lepreux
    Service d Anatomie Pathologique, CHU Bordeaux, France
    J Hepatol 39:77-85. 2003
    ..Liver adenomatosis is characterized by the presence of multiple adenomas of various sizes in the liver. The aim of this study was to characterize the morphology of small nodules which can be difficult to identify...
  18. doi Hepatocellular adenomas: magnetic resonance imaging features as a function of molecular pathological classification
    Hervé Laumonier
    Department of Radiology, CHU de Bordeaux, Hôpital Saint André, Bordeaux, France
    Hepatology 48:808-18. 2008
    ..5%, a negative predictive value of 84%, a sensitivity of 85.2%, and a specificity of 87.5% for the diagnosis of inflammatory HCA...
  19. ncbi Comparison of 2 regimens that include interferon-alpha-2a plus ribavirin for treatment of chronic hepatitis C in human immunodeficiency virus-coinfected patients
    Didier Neau
    Fédération des Maladies Infectieuses, Centre Hospitalo Universitaire Pellegrin, Bordeaux, France
    Clin Infect Dis 36:1564-71. 2003
    ..In conclusion, the combination of conventional IFN-alpha-2a and ribavirin has poor virological efficacy in HCV-HIV-coinfected patients...
  20. ncbi Hepatocellular adenoma subtype classification using molecular markers and immunohistochemistry
    Paulette Bioulac-Sage
    Department of Pathology, CHU Bordeaux, France
    Hepatology 46:740-8. 2007
    ..04). Previously described associations were confirmed and in particular the significant association between beta-catenin-activated HCA and hepatocellular carcinomas (HCC) at diagnosis or during follow-up (P < 10(-5))...
  21. ncbi Obesity as a risk factor for hepatocellular carcinoma in a noncirrhotic patient
    Laurent Gonzalez
    Fédération des spécialités digestives, CHU Bordeaux and GREF Inserm 0362 Université Bordeaux 2, Bordeaux, France
    Semin Liver Dis 24:415-9. 2004
  22. ncbi Detection of nodules in liver cirrhosis: spiral computed tomography or magnetic resonance imaging? A prospective study of 88 nodules in 34 patients
    Victor de Ledinghen
    Unite de Transplantation Hepatique, Hopital Pellegrin, Bordeaux, France
    Eur J Gastroenterol Hepatol 14:159-65. 2002
    ..However, tumour size is always a restricting factor for these two techniques, which are unable to detect small HCC in more than 60% of cases...
  23. doi Impact of tumor response on survival after radiochemotherapy in locally advanced rectal carcinoma
    Anne Rullier
    Department of Pathology, CHU Bordeaux, France
    Am J Surg Pathol 34:562-8. 2010
    ..Cellular-response gradings had no impact on survival even in stage II patients...
  24. ncbi Prognostic factors and longterm survival after hepatic resection for hepatocellular carcinoma originating from noncirrhotic liver
    Christophe Laurent
    Department of Surgery, Saint Andre Hospital, Bordeaux, France
    J Am Coll Surg 201:656-62. 2005
    ..Despite numerous publications on hepatic resection, prognostic factors for intrahepatic recurrence and survival are not well known for patients with HCC without cirrhosis...
  25. ncbi Mutation of TP53 gene is involved in carcinogenesis of hepatic undifferentiated (embryonal) sarcoma of the adult, in contrast with Wnt or telomerase pathways: an immunohistochemical study of three cases with genomic relation in two cases
    Sebastien Lepreux
    Service d Anatomie Pathologique, Hopital Pellegrin, CHU Bordeaux, 33076 Bordeaux, France
    J Hepatol 42:424-9. 2005
    ..Hepatic undifferentiated (embryonal) sarcoma (HUS) is an exceptional hepatic malignant tumor in adults. Genetic studies were never reported in adult cases...
  26. ncbi Prevalence of and factors associated with hepatic steatosis in patients coinfected with hepatitis C virus and HIV: Agence Nationale pour la Recherche contre le SIDA et les hépatites virales CO3 Aquitaine Cohort
    Didier Neau
    Fédération des Maladies Infectieuses et Tropicales, Centre Hospitalo Universitaire, Hopital Pellegrin, Bordeaux, France
    J Acquir Immune Defic Syndr 45:168-73. 2007
    ..The prevalence and factors associated with hepatic steatosis are not well defined in HCV-HIV-coinfected patients...
  27. doi Role of contrast-enhanced sonography in differentiation of subtypes of hepatocellular adenoma: correlation with MRI findings
    Hervé Laumonier
    Department of Radiology, Hôpital Saint André, 1 rue Jean Burguet, Bordeaux, 33076, France
    AJR Am J Roentgenol 199:341-8. 2012
    ..The aim of this study was to document the contrast-enhanced sonographic (CEUS) features specific for adenoma subtypes and to correlate them with MRI findings...
  28. ncbi Protease-activated receptor 1 knockout reduces experimentally induced liver fibrosis
    Anne Rullier
    INSERM U889, Universite Victor Segalen Bordeaux 2, 146, rue Leo Saignat, 33076 Bordeaux, France
    Am J Physiol Gastrointest Liver Physiol 294:G226-35. 2008
    ..Altogether, these results suggest that thrombin profibrogenic effects are independent of effects on blood coagulation and are instead due to direct effects on fibrogenic cells and possibly on T lymphocytes...
  29. ncbi Real-time monitoring of hepatocellular carcinoma radiofrequency ablation by quantitative temperature MRI
    Hervé Laumonier
    Department of Radiology, Hôpital Saint André, CHU Bordeaux, France
    Semin Liver Dis 26:391-7. 2006
  30. doi Validation and comparison of simple noninvasive indexes for predicting liver fibrosis in HIV-HCV-coinfected patients: ANRS CO3 Aquitaine cohort
    Marc Arthur Loko
    INSERM, U593, Bordeaux, France
    Am J Gastroenterol 103:1973-80. 2008
    ..Although an increasing number of noninvasive fibrosis markers are available in HCV-monoinfected patients, data on the performance of these tests in HIV-HCV-coinfected patients are lacking...
  31. doi Fibrogenic cell phenotype modifications during remodelling of normal and pathological human liver in cultured slices
    Christelle Guyot
    INSERM U889 and Université Victor Segalen Bordeaux 2, Bordeaux, France
    Liver Int 30:1529-40. 2010
    ..The debate concerning the potential remodelling and/or reversibility of cirrhotic lesions and biliary fibrosis is still open...
  32. ncbi Impact of colloid response on survival after preoperative radiotherapy in locally advanced rectal carcinoma
    Anne Rullier
    Department of Pathology, Pellegrin Hospital, Bordeaux, France
    Am J Surg Pathol 29:602-6. 2005
    ..The intermediate natural history of patients with colloid response suggests taking colloid response into account in postoperative tumor staging to optimize adjuvant therapy...
  33. pmc Plasma and liver hepatitis C virus variability in patients coinfected with human immunodeficiency virus
    Anne Christine Jouvencel
    Laboratoire de Virologie EA2968, Universite Victor Segalen Bordeaux 2, 146 rue Leo Saignat, 33076 Bordeaux, France
    J Clin Microbiol 44:1877-80. 2006
    ..In the patients coinfected with HIV, accumulated random mutations produced mostly nonsynonymous substitutions in contrast to the reduced HCV genetic variability seen after treatment...
  34. ncbi Thrombin inhibits migration of human hepatic myofibroblasts
    Jennifer Gillibert-Duplantier
    INSERM U889, Universite Victor Segalen Bordeaux 2, 146 rue Leo Saignat, 33076 Bordeaux Cedex, France
    Am J Physiol Gastrointest Liver Physiol 293:G128-36. 2007
    ..The fine tuning of myofibroblast migration may be one of the mechanisms used by thrombin to regulate liver fibrogenesis...
  35. pmc Unexpected discovery of 2 cases of hepatocyte nuclear factor 1alpha-mutated infracentimetic adenomatosis
    Hervé Laumonier
    Department of Radiology, Hôpital St André, CHU Bordeaux, 1 rue Jean Burguet, Bordeaux 33075, France
    World J Gastroenterol 14:4830-3. 2008
    ..These new tools may further our understanding of the link between adenomas/adenomatosis subtypes and their complications, and their association with other abnormalities...
  36. doi Rnd3/RhoE Is down-regulated in hepatocellular carcinoma and controls cellular invasion
    Florence Grise
    INSERM, Physiopathologie du Cancer du Foie, U1053, Bordeaux, France
    Hepatology 55:1766-75. 2012
    ..Rnd3 knockdown mediated tumor hepatocyte invasion in a matrix-metalloproteinase-independent, and Rac1-dependent manner...
  37. ncbi [Towards a new diagnostic approach to benign hepatocytic nodules]
    Paulette Bioulac-Sage
    Service d Anatomie Pathologique, Hopital Pellegrin, Paris, France
    Gastroenterol Clin Biol 29:641-4. 2005
  38. ncbi Proteomic analysis of differentially expressed proteins in hepatocellular carcinoma developed in patients with chronic viral hepatitis C
    Jean Frédéric Blanc
    INSERM, E362, IFR66 Bordeaux, Universite Victor Segalen Bordeaux 2, Bordeaux, France
    Proteomics 5:3778-89. 2005
    ..Variations in protein accumulation were confirmed for two selected proteins (apolipoprotein E, chloride intracellular channel 1) by Western blotting in ten additional cases of HCC developing in patients with viral hepatitis C...
  39. doi Differential expression of the anterior gradient protein-2 is a conserved feature during morphogenesis and carcinogenesis of the biliary tree
    Sebastien Lepreux
    INSERM U889, Universite Bordeaux 2, Bordeaux, France
    Liver Int 31:322-8. 2011
    ..The anterior gradient protein-2 (AGR2) is overexpressed in numerous tumours such as breast, prostate or pancreas carcinomas and recently reported in fibrolamellar hepatocellular carcinoma (HCC)...
  40. ncbi Multiple telangiectatic focal nodular hyperplasia: vascular abnormalities
    Sebastien Lepreux
    Service d Anatomie Pathologique, Hopital Pellegrin, CHU Bordeaux, France
    Virchows Arch 442:226-30. 2003
    ....
  41. doi Sorafenib-mediated targeting of the AAA⁺ ATPase p97/VCP leads to disruption of the secretory pathway, endoplasmic reticulum stress, and hepatocellular cancer cell death
    Ping Yi
    Institut National de la Santé et de la Recherche Medicale U1053, Bordeaux, France
    Mol Cancer Ther 11:2610-20. 2012
    ....
  42. pmc Value and limits of routine histology alone or combined with glutamine synthetase immunostaining in the diagnosis of hepatocellular adenoma subtypes on surgical specimens
    Paulette Bioulac-Sage
    Service d Anatomie Pathologique, Hopital Pellegrin, CHU Bordeaux, Place Amelie Raba Leon, 33075 Bordeaux cedex, France Inserm U1053 Université Bordeaux Segalen, 146 rue Leo Saignat, 33076 Bordeaux Cedex, France
    Int J Hepatol 2013:417323. 2013
    ..GS is essential to identify b-HCA. This study demonstrates that a "palliative" diagnostic approach can be proposed, when the panel of specific antibodies is not available...
  43. doi Usefulness of noninvasive tests in nodular regenerative hyperplasia of the liver
    David Laharie
    INSERM U853, Universite Victor Segalen Bordeaux 2, France
    Eur J Gastroenterol Hepatol 22:487-93. 2010
    ..The only way to diagnose nodular regenerative hyperplasia (NRH) is liver biopsy...
  44. ncbi Gaucher's disease and fatal hepatic fibrosis despite prolonged enzyme replacement therapy
    Yves Perel
    Department of Pediatrics, Onco Hematology Unit, University Hospital, 33076 Bordeaux, France
    Pediatrics 109:1170-3. 2002
    ..In some cases of Gaucher's disease, alternative strategies such as fractionated or further increased ERT, gene therapy, or glucosyltransferase inhibitor should be explored...
  45. ncbi Expression of protease-activated receptors and tissue factor in human liver
    Anne Rullier
    GREF Inserm E362, Universite Victor Segalen Bordeaux 2, 146, rue Leo Saignat, Bordeaux 33076, France
    Virchows Arch 448:46-51. 2006
    ..However, our data do not support a role for PARs or TF in HCC progression...
  46. doi Cytoplasmic expression of human telomerase catalytic protein (hTERT) in neutrophils: an immunoelectron microscopy study
    Sebastien Lepreux
    Laboratoire d Histologie Embryologie, UFR II, Universite Victor Segalen Bordeaux, France
    Ultrastruct Pathol 32:178-83. 2008
    ..hTR was not expressed. hTERT is expressed in the cytoplasm of neutrophils, but its roles-eventually extratelomeric effects-remain to be elucidated...
  47. ncbi Coexistence of inflammatory hepatocellular adenomas with HNF1α-inactivated adenomas: is there an association?
    Claire Castain
    Service de Pathologie, Hopital Pellegrin, CHU Bordeaux, Bordeaux, France INSERM U1053, Université Bordeaux Segalen, Bordeaux, France
    Histopathology 64:890-5. 2014
    ..To report the coexistence of inflammatory hepatocellular adenoma (IHCA) and HNF1α-inactivated HCA (H-HCA) in cases from a multicentre study...
  48. ncbi Fibrosis is worse in HIV-HCV patients with low-level immunodepression referred for HCV treatment than in HCV-matched patients
    Anne Rullier
    Department of Pathology, Bordeaux Hospital, Bordeaux, France
    Hum Pathol 35:1088-94. 2004
    ..Our data confirm the need to treat such patients against HCV, and suggest that HIV infection could favor fibrosis via the modulation of the intrahepatic immune response...
  49. doi Cirrhosis and constitutional telomerase mutations
    Jean Baptiste Hiriart
    Hopital Haut Leveque, CHU Bordeaux, Avenue de Magellan, 33604 Pessac, France
    Clin Res Hepatol Gastroenterol 35:607-9. 2011
    ..Given that telomere shortening has been associated with fibrosis progression, Calado et al. and Hartmann et al. recently focussed on telomerase gene mutations in human cirrhosis...
  50. ncbi Lymph nodes after preoperative chemoradiotherapy for rectal carcinoma: number, status, and impact on survival
    Anne Rullier
    Department of Pathology, CHU Bordeaux, France
    Am J Surg Pathol 32:45-50. 2008
    ....
  51. doi [Arterial myopericytoma: a case report]
    Anne Rullier
    Service d Anatomie Pathologique, Hopital Pellegrin, CHU de Bordeaux, Place Amelie Raba Leon, 33076 Bordeaux Cedex, France
    Ann Pathol 30:325-7. 2010
    ..Usually, the lesion is small and shows a myopericytic differentiation. The cells are short, fusiform and arranged concentrically around small vascular lumen. We reported here the second case of arterial mural myopericytoma...
  52. ncbi Clinical and molecular analysis of combined hepatocellular-cholangiocarcinomas
    Dominique Cazals-Hatem
    Department of Pathology, Hopital Beaujon, AP HP, 92110 Clichy, France
    J Hepatol 41:292-8. 2004
    ..To better understand the relations between cholangiocarcinoma (CC), HCC-CC and hepatocellular carcinoma (HCC), we screened for genetic alterations...
  53. doi ESM-1 expression in stromal cells is predictive of recurrence after radiofrequency ablation in early hepatocellular carcinoma
    Marianne Ziol
    Service d Anatomie Pathologique, Groupe hospitalier Paris Seine Saint Denis, Hopital Jean Verdier, AP HP, 93143 Bondy, France Université Paris 13, Sorbonne Paris Cité, UFR SMBH, F 93000 Bobigny, France
    J Hepatol 59:1264-70. 2013
    ..So far, no tissue biomarker of recurrence has been validated in biopsy samples. We aimed at investigating the prognostic value of tissue biomarkers in HCC biopsy samples of patients treated with RFA...
  54. ncbi [Angiopoietines play a physiopathological role in focal nodular hyperplasia]
    Paulette Bioulac-Sage
    Service d Anatomie Pathologique, Hopital Pellegrin, GREF INSERM E0362, Universite Bordeaux 2, 33000 Bordeaux
    Gastroenterol Clin Biol 28:200-1. 2004
  55. doi Molecular characterization of hepatocellular adenomas developed in patients with glycogen storage disease type I
    Julien Calderaro
    INSERM, UMR 674, Génomique fonctionnelle des tumeurs solides, IUH, F 75010 Paris, France
    J Hepatol 58:350-7. 2013
    ..Glycogen storage disease type I (GSD) is a rare hereditary metabolic disease that predisposes to HCA development. The aim of our study was to characterize the molecular profile of GSD-associated HCA...
  56. ncbi [Venous cystic adventitial disease: a case report]
    Laila Chbani
    Service d Anatomie Pathologique, Hopital Pellegrin, CHU de Bordeaux, Place Amelie Raba Leon, 33076 Bordeaux Cedex, France
    Ann Pathol 28:498-500. 2008
    ..As described, this lesion is characterized by an extrinsic compression of the vessel lumen by an adventitial myxoid nodule on histology. Recognition of this entity is important to ensure proper treatment...
  57. ncbi Case report of a patient with non-alcoholic fatty liver disease, moderate iron overload who is homozygous for the S65C mutation in the HFE1 gene
    Pierre Henri Bernard
    Service d Hepato Gastroenterologie, groupe hospitalier Saint André, CHU de Bordeaux, France
    Eur J Med Genet 48:195-8. 2005
  58. ncbi Abnormal hepatic expression of fibrillin-1 in children with cholestasis
    Thierry Lamireau
    Groupe de Recherches pour l Etude du Foie, Universite Victor Segalen, Bordeaux, France
    Am J Surg Pathol 26:637-46. 2002
    ..Finally, in normal and pathologic tissues, fibrillin-1 was co-localized with its putative receptor alphaVbeta3 in sinusoids but not around biliary structures...