Philippe Mathurin

Summary

Affiliation: CHRU de Lille
Country: France

Publications

  1. ncbi request reprint Corticosteroids for alcoholic hepatitis--what's next?
    Philippe Mathurin
    Service d Hépato Gastroentérologie Hôpital Claude Huriez 2 ème étage Est, Avenue Michel Polonovski, CHRU Lille 59037, France
    J Hepatol 43:526-33. 2005
  2. doi request reprint Early switch to pentoxifylline in patients with severe alcoholic hepatitis is inefficient in non-responders to corticosteroids
    Alexandre Louvet
    Services d Hépato gastroentérologie, Hopital Huriez, rue Polonovski, Lille, France
    J Hepatol 48:465-70. 2008
  3. ncbi request reprint Prospective study of the long-term effects of bariatric surgery on liver injury in patients without advanced disease
    Philippe Mathurin
    Service d Hepato Gastroenterologie, CHRU de Lille, Universite Lille 2, France
    Gastroenterology 137:532-40. 2009
  4. ncbi request reprint Infection in patients with severe alcoholic hepatitis treated with steroids: early response to therapy is the key factor
    Alexandre Louvet
    Service des Maladies de l Appareil digestif, Hopital Huriez, Lille, France
    Gastroenterology 137:541-8. 2009
  5. ncbi request reprint Fibrosis progression occurs in a subgroup of heavy drinkers with typical histological features
    P Mathurin
    Service Maladies de l Appareil Digestif, Hopital Huriez, CHRU de Lille, Lille, and ISERM 0114, Univ de Lille, Lille, France
    Aliment Pharmacol Ther 25:1047-54. 2007
  6. doi request reprint [Acute alcoholic hepatitis. Management practices for 2007]
    P Mathurin
    Service d Hepato Gastroenterologie, Hopital Claude Huriez, CHRU de Lille, Avenue Michel Polonovski, 59037 Lille Cedex, France
    Gastroenterol Clin Biol 32:S179-81. 2008
  7. ncbi request reprint [Cirrhosis: new concepts and great therapeutic progresses]
    Philippe Mathurin
    Service d Hepato Gastroenterologie, Hopital Claude Huriez, CHRU Lille, 59037 Lille Cedex
    Rev Prat 55:1525-6. 2005
  8. ncbi request reprint [Managing the complications of cirrhosis]
    Pierre Deltenre
    Service d Hepato Gastroenterologie, Hopital Claude Huriez, CHRU Lille, 59037 Lille Cedex
    Rev Prat 55:1555-63. 2005
  9. ncbi request reprint A patient with alcoholic liver failure referred for liver transplantation
    Philippe Mathurin
    Service d Hepato Gastroenterologie, Hopital Claude Huriez, Lille, France
    Liver Transpl 13:S83-6. 2007
  10. doi request reprint Treatment of severe forms of alcoholic hepatitis: where are we going?
    Philippe Mathurin
    Service d Hepato Gastroenterologie, Hôpital Huriez Lille, Lille, France
    J Gastroenterol Hepatol 23:S60-2. 2008

Detail Information

Publications68

  1. ncbi request reprint Corticosteroids for alcoholic hepatitis--what's next?
    Philippe Mathurin
    Service d Hépato Gastroentérologie Hôpital Claude Huriez 2 ème étage Est, Avenue Michel Polonovski, CHRU Lille 59037, France
    J Hepatol 43:526-33. 2005
  2. doi request reprint Early switch to pentoxifylline in patients with severe alcoholic hepatitis is inefficient in non-responders to corticosteroids
    Alexandre Louvet
    Services d Hépato gastroentérologie, Hopital Huriez, rue Polonovski, Lille, France
    J Hepatol 48:465-70. 2008
    ..A two-step strategy was evaluated consisting of early withdrawal of corticosteroids and a switch to pentoxifylline for 28 additional days in non-responders identified using early change in bilirubin level...
  3. ncbi request reprint Prospective study of the long-term effects of bariatric surgery on liver injury in patients without advanced disease
    Philippe Mathurin
    Service d Hepato Gastroenterologie, CHRU de Lille, Universite Lille 2, France
    Gastroenterology 137:532-40. 2009
    ..We performed a 5-year prospective study to evaluate fibrosis and nonalcoholic steatosis (NASH) in severely obese patients after bariatric surgery...
  4. ncbi request reprint Infection in patients with severe alcoholic hepatitis treated with steroids: early response to therapy is the key factor
    Alexandre Louvet
    Service des Maladies de l Appareil digestif, Hopital Huriez, Lille, France
    Gastroenterology 137:541-8. 2009
    ....
  5. ncbi request reprint Fibrosis progression occurs in a subgroup of heavy drinkers with typical histological features
    P Mathurin
    Service Maladies de l Appareil Digestif, Hopital Huriez, CHRU de Lille, Lille, and ISERM 0114, Univ de Lille, Lille, France
    Aliment Pharmacol Ther 25:1047-54. 2007
    ..Studies using consecutive liver biopsies constitute an attractive approach to gaining insight into the pathogenesis of alcoholic liver disease...
  6. doi request reprint [Acute alcoholic hepatitis. Management practices for 2007]
    P Mathurin
    Service d Hepato Gastroenterologie, Hopital Claude Huriez, CHRU de Lille, Avenue Michel Polonovski, 59037 Lille Cedex, France
    Gastroenterol Clin Biol 32:S179-81. 2008
  7. ncbi request reprint [Cirrhosis: new concepts and great therapeutic progresses]
    Philippe Mathurin
    Service d Hepato Gastroenterologie, Hopital Claude Huriez, CHRU Lille, 59037 Lille Cedex
    Rev Prat 55:1525-6. 2005
  8. ncbi request reprint [Managing the complications of cirrhosis]
    Pierre Deltenre
    Service d Hepato Gastroenterologie, Hopital Claude Huriez, CHRU Lille, 59037 Lille Cedex
    Rev Prat 55:1555-63. 2005
    ..The apparition of these complications constitutes a major event for the patient. In addition to the etiological treatment, take charge of complications can improve the prognosis of the patients...
  9. ncbi request reprint A patient with alcoholic liver failure referred for liver transplantation
    Philippe Mathurin
    Service d Hepato Gastroenterologie, Hopital Claude Huriez, Lille, France
    Liver Transpl 13:S83-6. 2007
  10. doi request reprint Treatment of severe forms of alcoholic hepatitis: where are we going?
    Philippe Mathurin
    Service d Hepato Gastroenterologie, Hôpital Huriez Lille, Lille, France
    J Gastroenterol Hepatol 23:S60-2. 2008
    ..Progress in understanding the pathogenesis of AH is opening up an exciting new era and is lending impetus to future evaluation of new drugs targeting the tumor necrosis factor pathways...
  11. ncbi request reprint The evolution of severe steatosis after bariatric surgery is related to insulin resistance
    Philippe Mathurin
    Service Maladie de l Appareil digestif, Hopital Huriez, CHRU Lille, Lille, France
    Gastroenterology 130:1617-24. 2006
    ..Our aim was to determine whether insulin resistance (IR) influences the histologic effects induced by bariatric surgery...
  12. doi request reprint [Alcohol and the liver]
    P Mathurin
    Service des Maladies de l Appareil digestif, Hopital Claude Huriez, CHRU, 59000 Lille, France
    Gastroenterol Clin Biol 33:840-9. 2009
    ..Only abstainers are considered as candidates for liver transplantation. The recent development of non invasive methods opens up new perspectives for the screening of cirrhosis in subjects with heavy drinking...
  13. ncbi request reprint Meta-analysis: evaluation of adjuvant therapy after curative liver resection for hepatocellular carcinoma
    P Mathurin
    Service d Hepatogastroenterologie, Hôpital Claude Hurriez, CHRU Lille, France
    Aliment Pharmacol Ther 17:1247-61. 2003
    ..To evaluate adjuvant modalities after curative resection for hepatocellular carcinoma using a meta-analysis of randomized and non-randomized controlled trials...
  14. doi request reprint Usefulness of viral kinetics for early prediction of a sustained virological response in HCV-1 non-responders re-treated with pegylated interferon and ribavirin
    Pierre Deltenre
    Service d Hepato Gastroenterologie, Hopital Huriez, CHRU Lille, Lille, France
    J Hepatol 55:989-95. 2011
    ..The aim of this study was to identify, in HCV-1 non-responders and relapsers to IFN or Peg-IFN and ribavirin, the earliest and most accurate predictor of failure to respond to a new treatment combining Peg-IFN and ribavirin...
  15. doi request reprint Impact of viral eradication on mortality related to hepatitis C: a modeling approach in France
    Sylvie Deuffic-Burban
    CTRS INSERM U795, CHRU Lille, Lille, France
    J Hepatol 49:175-83. 2008
    ..In France, two recent studies enabled modeling of the impact of viral eradication on HCV mortality...
  16. ncbi request reprint Hepatocellular carcinoma screening in patients with compensated hepatitis C virus (HCV)-related cirrhosis aware of their HCV status improves survival: a modeling approach
    Abbas Mourad
    INSERM U995, Universite Lille Nord de France, Lille, France IAME, UMR 1137, INSERM, Paris, France, Univ Paris Nord Sorbonne Paris Cité, Paris, France
    Hepatology 59:1471-81. 2014
    ..0001). Conclusion: The present study shows that US screening for HCC in patients with compensated HCV-related cirrhosis aware of their HCV status improves survival and emphasizes the crucial role of screening effectiveness...
  17. ncbi request reprint The Lille model: a new tool for therapeutic strategy in patients with severe alcoholic hepatitis treated with steroids
    Alexandre Louvet
    Services d Hépato gastroentérologie, Hopital Claude Huriez, Avenue Michel Polonovski, CHRU Lille, 59037 Lille, France
    Hepatology 45:1348-54. 2007
    ..Early identification of subjects with substantial risk of death according to the Lille model will improve management of patients suffering from severe AH and will aid in the design of future studies for alternative therapies...
  18. doi request reprint Predicted effects of treatment for HCV infection vary among European countries
    Sylvie Deuffic-Burban
    ATIP AVENIR INSERM Unité 995, Lille, France
    Gastroenterology 143:974-85.e14. 2012
    ..We also assessed the effects of treatment with pegylated interferon and additional effects of triple therapy with protease inhibitors...
  19. doi request reprint Prednisolone with vs without pentoxifylline and survival of patients with severe alcoholic hepatitis: a randomized clinical trial
    Philippe Mathurin
    Service des Maladies de l Appareil digestif, Hopital Huriez, Lille, France
    JAMA 310:1033-41. 2013
    ..Prednisolone or pentoxifylline is recommended for severe alcoholic hepatitis, a life-threatening disease. The benefit of their combination is unknown...
  20. doi request reprint Early liver transplantation for severe alcoholic hepatitis
    Philippe Mathurin
    Hopital Claude Huriez, Services Maladies de l Appareil Digestif and INSERM Unité 995, Centre Hospitalier Universitaire, de Lille and Université Nord de France, Lille
    N Engl J Med 365:1790-800. 2011
    ..Patients whose hepatitis is not responding to medical therapy have a 6-month survival rate of approximately 30%. Since most alcoholic hepatitis deaths occur within 2 months, early liver transplantation is attractive but controversial...
  21. doi request reprint Impact of pegylated interferon and ribavirin on morbidity and mortality in patients with chronic hepatitis C and normal aminotransferases in France
    Sylvie Deuffic-Burban
    Institut National de la Santé et de la Recherche Médicale U795, Faculte de Medecine, Pole Recherche, Lille, France
    Hepatology 50:1351-9. 2009
    ..If N-ALT patients are treated at the same proportions as those with E-ALT, morbidity and mortality could be further reduced by 1400 cases of cirrhosis (13%, 1200-2200), 600 complications (9%, 600-1000), and 500 deaths (9%, 500-800)...
  22. doi request reprint Impact of insulin resistance on sustained response in HCV patients treated with pegylated interferon and ribavirin: a meta-analysis
    Pierre Deltenre
    Service d Hepato Gastroenterologie, Hopital Huriez, CHRU Lille, Lille, France
    J Hepatol 55:1187-94. 2011
    ..We aimed to confirm the role of IR assessed by the homoeostasis model assessment (HOMA-IR) on SVR and to determine its magnitude...
  23. doi request reprint Validation of noninvasive biomarkers (FibroTest, SteatoTest, and NashTest) for prediction of liver injury in patients with morbid obesity
    Guillaume Lassailly
    Service des Maladies de l Appareil digestif, Université Lille2, CHRU de Lille, Université Lille2, France
    Eur J Gastroenterol Hepatol 23:499-506. 2011
    ..The aim of this study was to determine the diagnostic utility of noninvasive markers of fibrosis (FibroTest), steatosis (SteatoTest), and steatohepatitis (NashTest, ActiTest) in these patients...
  24. doi request reprint Impact of hepatitis C triple therapy availability upon the number of patients to be treated and associated costs in France: a model-based analysis
    Sylvie Deuffic-Burban
    ATIP AVENIR Inserm U995, Universite Lille Nord de France, Lille, France
    Gut 61:290-6. 2012
    ..The aim of this study was to estimate the number of G1 patients to be treated in France in 2012 and associated costs...
  25. ncbi request reprint Evaluation of amantadine in chronic hepatitis C: a meta-analysis
    Pierre Deltenre
    Services d Hépato gastroentérologie, Hopital Huriez, CHRU Lille, France
    J Hepatol 41:462-73. 2004
    ..The benefit of amantadine combination therapy, either with interferon (IFN) alone (double therapy) or with ribavirin and IFN (triple therapy) is unknown...
  26. doi request reprint Impact of impaired aerobic capacity on liver transplant candidates
    Sebastien Dharancy
    Service des maladies de l appareil digestif et de la nutrition, Hopital Claude Huriez, France
    Transplantation 86:1077-83. 2008
    ....
  27. doi request reprint Neutrophil migration during liver injury is under nucleotide-binding oligomerization domain 1 control
    Sebastien Dharancy
    INSERM U995, Lille, France
    Gastroenterology 138:1546-56, 1556.e1-5. 2010
    ..Our aim was to explore the role of NOD1 in PMN-induced liver injury...
  28. ncbi request reprint [Effects of bariatric surgery on the liver]
    Florent Gonzalez
    Services des Maladies de l Appareil Digestif et de la Nutrition, Hopital Claude Huriez, CHRU de Lille
    Gastroenterol Clin Biol 29:280-6. 2005
  29. doi request reprint Impact of emerging hepatitis C virus treatments on future needs for liver transplantation in France: a modelling approach
    Sylvie Deuffic-Burban
    INSERM U995, University of Lille Nord de France, Lille, France Inserm ATIP AVENIR, Denis Diderot University, Paris, France
    Dig Liver Dis 46:157-63. 2014
    ....
  30. ncbi request reprint Phase II trial of docetaxel therapy in patients with advanced hepatocellular carcinoma
    Mohamed Hebbar
    Unité d Oncologie Médicale, Centre Hospitalo Universitaire, Lille, France
    Oncology 70:154-8. 2006
    ..We assessed the safety and efficacy of docetaxel, a microtubule inhibitor, in patients with advanced hepatocellular carcinoma (HCC)...
  31. ncbi request reprint [Problems with therapeutic acetaminophen use in excessive drinkers]
    Alexandre Louvet
    Service d Hepatogastroenterologie, Hôpital Huriez CHRU, Lille
    Gastroenterol Clin Biol 30:769-74. 2006
  32. doi request reprint [Daily life, pregnancy, and quality of life after liver transplantation]
    Amélie Cannesson
    Maladies de l appareil digestif et de la nutrition, Pôle de médecine Huriez, Hopital Huriez, CHRU Lille, Lille, France
    Presse Med 38:1319-24. 2009
    ..The global perception of quality of life increases after liver transplantation, but remains lower than in healthy subjects...
  33. ncbi request reprint Comparison of two techniques of transarterial chemoembolization before liver transplantation for hepatocellular carcinoma: a case-control study
    Sebastien Dharancy
    Service des maladies de l appareil digestif et de la nutrition, Hopital Huriez, CHU Lille, France
    Liver Transpl 13:665-71. 2007
    ..This study observed trends toward improvement in the disease-free survival of patients with uninodular HCC < or =5 cm. Future studies focusing on such patients are warranted...
  34. ncbi request reprint Anticoagulation therapy may reverse biliary abnormalities due to acute portal thrombosis
    Alexandre Louvet
    Services de Maladies de l Appareil Digestif, Hôpital Claude Huriez 2émeétage Est, Lille, France
    Dig Dis Sci 51:11-7. 2006
  35. ncbi request reprint Impaired expression of the peroxisome proliferator-activated receptor alpha during hepatitis C virus infection
    Sebastien Dharancy
    Equipe Mixte INSERM 0114, Centre Hospitalier Universitaire, Lille, France
    Gastroenterology 128:334-42. 2005
    ....
  36. doi request reprint Assessing bone status in patients awaiting liver transplantation
    Cécile Wibaux
    Service de Rhumatologie, Département Universitaire de Rhumatologie, Université Nord de France, Hopital Roger Salengro, CHRU de Lille, Lille, France
    Joint Bone Spine 78:387-91. 2011
    ..Osteoporosis is common in liver transplant recipients as a result of both iatrogenic factors and preexisting hepatic osteodystrophy...
  37. ncbi request reprint [Membranous glomerulonephritis complicating hepatocellular carcinoma]
    Frederic Texier
    Maladies de l appareil digestif et de la nutrition, Hopital Claude Huriez, CHRU Lille
    Gastroenterol Clin Biol 28:605-7. 2004
    ..The patient's course was temporarily stabilized with loop diuretics and dialysis but the patient died of hemoperitoneum from a ruptured tumor...
  38. doi request reprint Corticosteroids improve short-term survival in patients with severe alcoholic hepatitis: meta-analysis of individual patient data
    Philippe Mathurin
    Service des Maladies de l Appareil digestif, Hopital Huriez, rue Polonovski, F 59037 Lille, France
    Gut 60:255-60. 2011
    ..This approach overcomes limitations associated with the use of literature data and improves the relevance of the study and estimates of effect size...
  39. ncbi request reprint [Treatment of chronic hepatitis C and alcohol consumption]
    Philippe Mathurin
    Service d Hepatogastroenterologie, CHRU de Lille
    Gastroenterol Clin Biol 26:B248-51. 2002
  40. ncbi request reprint Conversion to sirolimus: a useful strategy for recalcitrant cutaneous viral warts in liver transplant recipient
    Sebastien Dharancy
    Service des maladies de l appareil digestif et de la nutrition, Lille, France
    Liver Transpl 12:1883-7. 2006
    ..Conversion to sirolimus was followed by a rapid improvement of cutaneous state suggesting that this strategy may be useful for recalcitrant cutaneous viral warts in transplant recipient...
  41. doi request reprint Immediate vs. delayed treatment in patients with acute hepatitis C based on IL28B polymorphism: a model-based analysis
    Sylvie Deuffic-Burban
    Inserm ATIP AVENIR Modélisation, aide à la décision et coût efficacité en maladies infectieuses, Lille Paris, France
    J Hepatol 57:260-6. 2012
    ....
  42. doi request reprint Ultrasonographic surveillance of hepatocellular carcinoma in cirrhosis: a randomized trial comparing 3- and 6-month periodicities
    Jean Claude Trinchet
    AP HP, Hopital Jean Verdier, Service d Hepato Gastroenterologie, Bondy, F 93140, France
    Hepatology 54:1987-97. 2011
    ..Conclusion: US surveillance, performed every 3 months, detects more small focal lesions than US every 6 months, but does not improve detection of small HCC, probably because of limitations in recall procedures...
  43. pmc Peroxisome Proliferator-Activated Receptors in HCV-Related Infection
    Sebastien Dharancy
    Unité INSERM 795, Universite Lille 2, Service des maladies de l appareil digestif et de la nutrition, Hopital Huriez, CHRU Lille, 59037 Lille, France
    PPAR Res 2009:357204. 2009
    ..The available nonhepatotoxic agonists of PPARs may constitute a progress in the therapeutic management of patients chronically infected with HCV...
  44. doi request reprint NOD2: a potential target for regulating liver injury
    Mathilde Body-Malapel
    INSERM U795, Lille, France
    Lab Invest 88:318-27. 2008
    ..Taken together, our results indicate that NOD2 may represent a new therapeutic target in liver diseases...
  45. ncbi request reprint Effect of terlipressin (Glypressin) on hepatorenal syndrome in cirrhotic patients: results of a multicentre pilot study
    Chantal Halimi
    Service d Hepato Gastroenterologie, Centre Hospitalier de Senlis, Paris, France
    Eur J Gastroenterol Hepatol 14:153-8. 2002
    ..Promising results have been shown with this drug. The purpose of this multicentre retrospective study was to evaluate the effects of terlipressin on renal function and survival of patients with HRS...
  46. ncbi request reprint Early change in bilirubin levels is an important prognostic factor in severe alcoholic hepatitis treated with prednisolone
    Philippe Mathurin
    Sce d Hépato Gastroentérologie, Hôpital Claude Hurriez, and Inserm EPI 0114 Lille, Paris, France
    Hepatology 38:1363-9. 2003
    ..In conclusion, ECBL is a very simple predictive factor for identifying nonresponders. A recommendation to discontinue corticosteroids after 7 days in patients without ECBL, suggested by our results, awaits additional confirmation...
  47. ncbi request reprint A comparison of fibrosis progression in chronic liver diseases
    Thierry Poynard
    Service d Hepato Gastroenterologie, Groupe Hospitalier Pitie Salpetriere, et UPRESA 8067 CNRS, 47 83 boulevard de l Hopital, 75651 Paris Cedex 13, France
    J Hepatol 38:257-65. 2003
    ..No study has compared the liver fibrosis progression rates among chronic liver diseases and the risk factors in order to better organize screening strategies...
  48. doi request reprint Modelling the past, current and future HCV burden in France: detailed analysis and perspectives
    Sylvie Deuffic-Burban
    CTRS INSERM U795, CHRU Lille, Lille, France
    Stat Methods Med Res 18:233-52. 2009
    ..The models offered a useful tool to assess public health policy scenarios in planning healthcare responses to the HCV epidemic...
  49. ncbi request reprint The immunology of fibrogenesis in alcoholic liver disease
    Antonio Chedid
    Department of Pathology, Rosalind Franklin University Chicago Medical School, North Chicago, Ill 60064, USA
    Arch Pathol Lab Med 128:1230-8. 2004
    ..During the past decade, several animal models and human studies have attributed fibrogenesis in the liver to the role played by hepatocytes, Kupffer cells, endothelial cells, and especially stellate cells...
  50. ncbi request reprint Corticosteroids improve short-term survival in patients with severe alcoholic hepatitis (AH): individual data analysis of the last three randomized placebo controlled double blind trials of corticosteroids in severe AH
    Philippe Mathurin
    Hopital Antoine Beclere, Clamart, France
    J Hepatol 36:480-7. 2002
    ....
  51. ncbi request reprint A double-blind randomized controlled trial of infliximab associated with prednisolone in acute alcoholic hepatitis
    Sylvie Naveau
    Services d Hépato gastroentérologie, Hopital Antoine Beclere, Clamart, Assistance Publique Hopitaux de Paris, France
    Hepatology 39:1390-7. 2004
    ..In conclusion, three infusions of 10 mg/kg of infliximab in association with prednisolone may be harmful in patients with severe AAH because of the high prevalence of severe infections...
  52. ncbi request reprint Polymorphonuclear neutrophils are a source of hepatocyte growth factor in patients with severe alcoholic hepatitis
    Julien Taieb
    Hepatology Department, Pitie Salpetriere Hospital, 47, Boulevard de l Hopital, 75651, Cedex 13, Paris, France
    J Hepatol 36:342-8. 2002
    ..As AH is accompanied by inflammation, neutrophilia and polymorphonuclear neutrophil (PMN) infiltration of the liver, we postulated that PMN could be a source of HGF in such patients...
  53. ncbi request reprint Is alcoholic hepatitis an indication for transplantation? Current management and outcomes
    Philippe Mathurin
    Service d Hépatogastroentérologie Hôpital Claude Huriez and Equipe mixte INSERM 0114, CHU Lille, France
    Liver Transpl . 2005
    ..5. Therefore, a reasonable approach would be to carry out only pilot studies on only a small cohort of patients to determine whether transplantation improves survival in patients with severe AH...
  54. ncbi request reprint [Interview: questions to Philippe Mathurin]
    Philippe Mathurin
    Gastroenterol Clin Biol 30:560-2. 2006
  55. ncbi request reprint [Alcohol, metabolic syndrome and obesity: impact on treatment efficacy]
    Lawrence Serfaty
    INSERM U680, Service d Hepatologie, Hopital Saint Antoine, 184 rue du Faubourg Saint Antoine, 75012 Paris, France
    Gastroenterol Clin Biol 31:4S40-3. 2007
    ..Efficacy of insulin sensitizing agents on virological response in patients treated with bi-therapy is under investigation in randomized controlled trials...
  56. ncbi request reprint [Alcoholic hepatitis: pathophysiological data and therapeutic perspectives]
    Philippe Mathurin
    Gastroenterol Clin Biol 28:D103-11. 2004
  57. ncbi request reprint [Acute recurrent pancreatitis in a composite CFTR heterozygote and Spink1 heterozygote patient]
    Frederic Texier
    Gastroenterol Clin Biol 30:630-1. 2006
  58. ncbi request reprint Diagnostic accuracy of the Multistix 8 SG reagent strip in diagnosis of spontaneous bacterial peritonitis
    Jean Baptiste Nousbaum
    Services d Hépato Gastroentérologie de, Brest, U773, Centre de Recherche Biomedicale Bichat Beaujon CRB3, Hopital Beaujon, Clichy, France
    Hepatology 45:1275-81. 2007
    ..04). Using a threshold of 2+ for positivity of the reagent strip, sensitivity was 45.3% for the diagnosis of SBP, specificity was 99.2%, positive predictive value was 77.9%, and negative predictive value was 96.9%...
  59. ncbi request reprint [Non alcoholic steatohepatitis: the future in hepatology?]
    Philippe Mathurin
    Gastroenterol Clin Biol 26:471-2. 2002
  60. ncbi request reprint Mass spectrometric approach for screening modifications of total serum N-glycome in human diseases: application to cirrhosis
    Willy Morelle
    Unité Mixte de Recherche CNRS USTL 8576, Glycobiologie Structurale et Fonctionnelle, Université des Sciences et Technologis de Lille 1, 59655 Villeneuve d Ascq, France
    Glycobiology 16:281-93. 2006
    ..The study of total serum N-glycome modifications is a preliminary for the discovery of new noninvasive diagnostic or prognostic biomarkers resulting from the variations of the N-glycan metabolism during diseases...
  61. ncbi request reprint Prothrombin index decrease: a useful and reliable marker of extensive fibrosis?
    Jean Francois Cadranel
    Unité d Hépatologie, Hopital Laennec, BP 72, 60109 Creil Cedex, France
    Eur J Gastroenterol Hepatol 14:1057-9. 2002
    ..Among those serum markers, we focused on prothrombin index, which seems to be a reliable and non-expansive marker for the diagnosis of extensive fibrosis...
  62. ncbi request reprint Uncovered transjugular intrahepatic portosystemic shunt for refractory ascites
    Pierre Deltenre
    Gastroenterology 130:1372-3; author reply 1373. 2006
  63. ncbi request reprint Hepatitis C virus therapy to date
    Graham Foster
    Queen Mary Hospital, University of London, London, UK
    Antivir Ther 13:3-8. 2008
    ....
  64. ncbi request reprint Alcoholic liver injury and apoptosis--synopsis of the symposium held at ESBRA 2001: 8th Congress of the European Society for Biomedical Research on Alcoholism, Paris, September 16, 2001
    Manuela G Neuman
    Division of Clinical Pharmacology, Sunnybrook and Women s College Health Sciences Centre, Room E235, 2075 Bayview Ave, Ontario, M4N 3M5, Toronto, Canada
    Alcohol 28:117-28. 2002
  65. ncbi request reprint Usefulness of routine analysis of ascitic fluid at the time of therapeutic paracentesis in asymptomatic outpatients. Results of a multicenter prospective study
    Rémy Romney
    Service d Hépato Gastroentérologie et Diabétologie, Centre Hospitalier Laennec, Creil
    Gastroenterol Clin Biol 29:275-9. 2005
    ..The aim of the study was to evaluate the prevalence of spontaneous bacterial peritonitis and culture-negative neutrocytic ascites in a large population of consecutive asymptomatic cirrhotic ascitic ambulatory patients...
  66. ncbi request reprint [Celiac disease and liver involvement]
    Thierry Thevenot
    Service d Hepato Gastroenterologie, Centre Hospitalier de Cambrai
    Gastroenterol Clin Biol 27:28-42. 2003
  67. ncbi request reprint [Inflammatory bowel disease and latent thrombocythemia: a novel cause of hepatic vein thrombosis?]
    Thomas Decaens
    Service d Hepatogastroenterologie, Hôpital Antoine Béclere France
    Gastroenterol Clin Biol 28:394-7. 2004
    ..Moreover, this case-report suggests that administration of heparin at the onset of the thrombosis may induce a complete regression of the thrombus in hepatic veins...
  68. pmc micro-Opioid receptor activation prevents acute hepatic inflammation and cell death
    Dania Chakass
    Institut National de la Santé et de la Recherche Médicale INSERM U795, University of Lille 2, Digestive Tract Diseases and Nutrition Department, 59037, Lille Cedex, France
    Gut 56:974-81. 2007
    ....