C Mariette

..In conclusion, the clinical, histologic, and oncologic differences between SCC and ADC justify a differentiated therapeutic concept for these two tumor entities and distinct consideration in clinical reports...

..Mesenteric panniculitis usually has an uneventful clinical course and resolves spontaneously in a variable delay...

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..For patients whose tumor is inoperable, a combination of radiation and chemotherapy is the standard treatment...

..This new technology should enable a better preparation of young surgeons for the operating room of the future...

..Through a team approach, members from all diagnostic and therapeutic disciplines, such as gastroenterologists, surgeons, oncologists, radiologists, and radiotherapists, can effectively administer a range of treatment modalities...

..To document the results of surgery alone in patients with localised oesophageal carcinoma...

..To identify factors affecting postoperative course and survival after esophagectomy for cancer and reasons for improved survival over time...

..Surgery appears more and more as an adjuvant therapy in the curative treatment of oesophageal cancer, especially for advanced tumours...

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..Imaging exams such as CT will aid in diagnosis and guide the therapeutic approach. Treatment specifically adapted to the etiologic cause must be thorough and complete from the start...

..Anastomotic leak, conduit necrosis, and pulmonary failure are the most serious complications. The management of complications following oesophagectomy is reviewed in the following section...

..We conducted a prospective cohort study to assess the acceptability, feasibility and safety of day-case laparoscopic fundoplication for gastroesophageal reflux disease in an university-based tertiary care center...

..The aim of this study was to determine the effect of neoadjuvant radiochemotherapy (RCT) on postoperative complications and survival after surgery for locally advanced oesophageal squamous cell carcinoma...

..Articles from the surgical literature with the highest levels of evidence are analyzed. Practical guidelines for treatment choice are proposed...

..Moreover, surgery should be kept in mind as salvage treatment in patients with no morphological response or persistent tumour after definitive chemoradiotherapy...

..In a question-and-answer format, we discuss the practical aspects of prescribing immunonutrition to provide assistance in this area and thus optimize the application of the guidelines and patient management...

..Long-term follow-up is required to evaluate dysphagia and quality-of-life...

..A multidisciplinary approach is essential for optimal diagnosis and management...

..Intrathoracic, covered oesophageal stents appears to reduce leak-morbidity after oesophagectomy and may be considered as a cost-effective treatment alternative...

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..In adenocarcinomas of the OGJ that can be treated curatively, a transection with a 8 cm oesophagectomy above the tumour in fresh specimen should be performed, and by thoracoabdominal approach for tumours type I and II...

..016). CONCLUSION: Complete surgical resection allows 5-year survival. Factors predictive of long-term survival assessed in preoperative evaluation, dysphagia and tumour stage, should be useful to select patients for neoadjuvant treatment...

..CONCLUSION: Surgical ablation is a viable option for advanced hypopharyngeal and cervical oesophageal neoplasms, and stomach interposition is the preferred method of reconstruction...

..Salvage surgery may have a survival benefit otherwise complete. Our aim was to identify predictors of R0 resection in these patients...

..Further prospective studies are needed to confirm the equivalence between transthoracic and transabdominal approaches...

..These results support the proposal that EUS should be performed in all patients with oesophageal cancer, not only for staging patients before therapy but also to determine prognosis...

..009). CONCLUSION: Our study confirms that dysphagia and nodal involvement on the CT-scan are simple preoperative prognostic factors in patients with resectable squamous cell carcinoma of the thoracic esophagus...

..This new mechanism of regulation of MUC4 mucin gene points out an important role for bile acids as key molecules in targeting MUC4 overexpression in early stages of oesophageal carcinogenesis...

..Deviation axis on the barium swallow and morphologic response to neoadjuvant radiochemotherapy are variables available for all patients at onset of therapeutic management...

..To conclude, FOLFIRI regimen appears quite active, with an acceptable safety profile in patients with advanced esophageal or junctional adenocarcinoma...

..Long-term treatment with an anti-secretory proton pump inhibitor may decrease esophageal complications of duodeno-gastric-esophageal reflux and could prevent the recurrence of gastric tube ulcers...

..Without definitively ruling out any possible impact of chronomodulation in that setting, our data reinforce the need of a better selection of patients aimed to be treated by CRT plus surgery...

..We need to improve postchemoradiotherapy restaging to be sure that chemoradiotherapy will provide the same long-term survival rates as surgery...

..Cervical and upper-third thoracic oesophageal carcinomas are considered as a single pathological entity. The aim of this study was to compare postoperative and oncological results after surgical resection in these two locations...

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..The aim of this study was to test the hypothesis that hybrid minimally invasive oesophagectomy (HMIO) decreases the 30-day MPPC rate without compromising oncological outcomes...

..To assess the acceptability, feasibility and results of day-case laparoscopic fundoplication for gastro-esophageal reflux disease (GERD) in an university tertiary care center...

..We report three cases of patients who had this clinical presentation. We suggest an approach to postoperative management of ESCC to identify early tumors in gastric tubes and to allow endoscopic or surgical curative treatment...

..Surgery may be proposed for selected non-responders patients and some complete pathology response in expert center...

..Oesophagectomy for carcinoma can be viewed as comprising two components: resection of the oesophagus and resection of the enveloping lymphatics. Controversy exists regarding how extensive these two components should be...

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..In the long-term, quality of life seems better mainly in patients with small-resected tumors associated with a good prognosis...

..These results bring new insights into MUC4 up-regulation in oesophageal carcinoma associated with bile reflux...

..Photodynamic therapy is an endoscopic treatment of early cancers based on the photosensitisation of neoplasms following the administration of a photosensitiser prior to laser light-induced tissue destruction...

..As far as other barrier agents are concerned, data are still insufficient to recommend them for clinical use. There is a need for other randomised controlled trials in order to evaluate functional efficiency of anti adhesion agents...

..To test the hypothesis that signet ring cell (SRC) histology has a negative prognostic value in patients with gastric adenocarcinoma (ADC)...

..Therapeutic strategies have markedly changed for 10 years, and their respective place is specified for each histological types and according to tumour location...

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..The aim of this study was to report two cases of transhiatal herniation following esophagectomy, to analyse the contributing factors of this complication and to expose the preventive treatment, by means of a review of the literature...

..04).CONCLUSION: Complete resection of esophageal cancer is predictable. After validation with an independent population the findings presented here could be used to establish stratification criteria for future therapeutic trials...

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..Articles from the surgical literature with the highest levels of evidence are analyzed. Practical guidelines for treatment choice are proposed...

..Articles from the surgical literature with the highest levels of evidence are analyzed. Practical guidelines for treatment choice are proposed...

..This pathological association appears non hasardous and surgical ampullectomy offers a good alternative to pancreaticoduodenectomy in localised tumors treatment...

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..Therefore, a randomized trial was carried out to compare, in responders only, chemoradiation alone with chemoradiation followed by surgery in patients with locally advanced tumors...

..015), age more than 60 years (p < 0.001), anastomotic leakage (p < 0.001), and abdominal complications (p = 0.003). CONCLUSIONS: ASA score is a reliable predictive factor of operative mortality and morbidity after resection of AGEJ...

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..This knowledge may be clinically exploited to predict the immunogenicity and hence the efficacy of chemotherapeutic regimens...