Research Topics
| F LeclercSummaryAffiliation: CHRU de Lille Country: France Publications
| Collaborators
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Detail Information
Publications
Differences in organ dysfunctions between neonates and older children: a prospective, observational, multicenter studyNawar Bestati
Service de Réanimation Pédiatrique, Univ Lille Nord de France, UDSL, EA2694, CHU Lille, avenue Eugene Avinee, 59037 Lille, France
Crit Care 14:R202. 2010..The objective of the study was to determine whether there are differences in incidence of ODs and mortality rate between full-term neonates (age <28 days) and older children...
Noninvasive positive pressure ventilation for acute respiratory failure in children: a concise reviewAbolfazl Najaf-Zadeh
Univ Lille Nord de France, UDSL, EA 2694, F 59000 Lille, France
Ann Intensive Care 1:15. 2011..Further randomized, controlled trials that address these issues in children with ARF are recommended...
[Weaning from invasive mechanical ventilation in pediatric patients (excluding premature neonates)]F Leclerc
Service de Réanimation Pédiatrique, CHRU de Lille, Universite de Lille 2, avenue Eugene Avinee, 59037 Lille Cedex, France
Arch Pediatr 17:399-406. 2010..The use of noninvasive ventilation is increasing and its place in weaning protocols for children needs to be determined; it might modify the definitions of weaning failure and weaning success in the future...
[Treatment of meningococcal purpura fulminans]F Leclerc
Service de Réanimation Pédiatrique, Hopital Jeanne de Flandre, 2, Avenue Oscar Lambret, 59037 Lille, France
Arch Pediatr 8:677s-688s. 2001..Cases must be rapidly notified to the Public Health Service who will institute chemoprophylaxis for close contacts. Given the predominance of serogroup B in France, we hope that an efficient vaccine will soon become available...
[Why teams in charge of children after a pediatric intensive care unit stay do not take into account the treatment limitation decisions previously made by intensivists]R Cremer
Service de Réanimation Pédiatrique, Hopital Jeanne de Flandre, CHU de Lille, Lille Cedex, France
Arch Pediatr 16:1233-44. 2009..A previous study pointed out that the teams in charge of children after the PICU stay did not take previous PICU LTDs into account...
Ventilator-induced overdistension in children: dynamic versus low-flow inflation volume-pressure curvesV Neve
Service de Réanimation Pédiatrique, Centre Hospitalier et Universitaire de Lille, Lille, France
Am J Respir Crit Care Med 162:139-47. 2000..In conclusion, quasi-static V-P curves can easily be obtained in children with the LFI technique. SOPE offers a good detection of OD on dynamic and LFI V-P curves but the C20/C index seems to be an inadequate measure of OD...
Are the GFRUP's recommendations for withholding or withdrawing treatments in critically ill children applicable? Results of a two-year surveyR Cremer
Réanimation Pédiatrique, Hopital Jeanne de Flandre, CHU de Lille, 59037 Lille, France
J Med Ethics 33:128-33. 2007....
[Non-invasive ventilation in infants with severe infection presumably due to respiratory syncytial virus: feasibility and failure criteria]A Campion
, , 59037 Lille Cedex, France
Arch Pediatr 13:1404-9. 2006..CONCLUSION: In infants with RSV and needing respiratory support, NIV represented the sole method of respiratory support in 68% of cases. NIV failure criteria were apneas, high values of admission PCO2 and H24 PRISM score...
[Syncope and pre-syncope in children and adolescents: a prospective study in a pediatric emergency care unit]O Noizet-Yverneau
Service d Urgences Pédiatriques, pôle de l urgence, CHRU de Lille, 2, Avenue Oscar Lambret, 59037 Lille Cedex, France
Arch Pediatr 16:1111-7. 2009..To assess in a pediatric emergency care unit (PECU): 1. The frequency of syncope and pre-syncope, 2. The incidence of diagnoses, 3. The value of investigations and cardiology and neurology consultations...
[What become the decisions of limitation of treatments after discharge from the paediatric intensive care unit?]R Cremer
Réanimation Pédiatrique, Hopital Jeanne de Flandre, CHRU de Lille, 59037 Lille, France
Arch Pediatr 15:1174-82. 2008..Although the French-speaking Group of Paediatric Intensive and Emergency Care (GFRUP) has published guidelines for limitation of treatments in PICU, outcome of these surviving children has not yet been studied...
Recognising haemorrhagic rash in children with fever: a survey of parents' knowledgeM Aurel
Paediatric Emergency and Infectious Diseases Unit, University of Lille Nord de France, CHU Lille, 2 Avenue Oscar Lambret, Lille Cedex, France
Arch Dis Child 96:697-8. 2011..Early recognition and treatment of meningococcal disease improves its outcome. Haemorrhagic rash is one of the most specific signs that parents can learn to recognise...
Overdistension in ventilated childrenV Neve
Service de Réanimation Pédiatrique, Centre Hospitalier et Universitaire de Lille, Lille, France
Crit Care 5:196-203. 2001....
[Rehydration modalities for acute diarrhea in hospitalized infants. Impact of a permanent short-stay pediatric observation unit]A Martinot
Clinique de Pediatrie, Hopital Jeanne de Flandre, Centre Hospitalier et Universitaire, Lille, France
Arch Pediatr 8:1062-70. 2001....
[Purpura fulminans and coxsackie B2 co-infection]C Fourier
Service de Réanimation Pédiatrique, Hopital Jeanne de Flandre, 2 av Oscar Lambret, F59037 Lille
Presse Med 30:1589-91. 2001..During septic shock in children, myocardial deficiency usually lasts 3 to 6 days. When prolonged, an other etiology should be looked for...
Do new strategies in meningococcemia produce better outcomes?F Leclerc
Pediatric Intensive Care Unit, University Hospital of Lille, France
Crit Care Med 28:S60-3. 2000..At present, early recognition of meningococcal sepsis and appropriate treatment seem to be the optimal methods of improving outcome. Efforts to find an effective meningococcal vaccine must be continued...
[Multi-parameter indices of weaning from mechanical ventilation in children]F Leclerc
Service de Réanimation Pédiatrique, Hopital Jeanne de Flandre, CHU de Lille, Lille
Rev Mal Respir 19:53-61. 2002..The aim of this study was to test the value of the pediatric CROP and RSB (CROPp, RSBp) and the accuracy of a simplified pediatric CROP (CROPpS) that does not require an arterial blood gas sample...
[Pediatric intermediate care: official French texts]F Leclerc
, , CHU de Lille, France
Arch Pediatr 15:679-82. 2008
[Purpura fulminans: what do hormonal and haemostatic treatments add?]F Leclerc
Service de Réanimation Pédiatrique, Hopital Jeanne de Flandre, CHU de Lille, Lille, France
Arch Pediatr 12:755-7. 2005
Noradrenaline use for septic shock in children: doses, routes of administration and complicationsM E Lampin
PICU, University Hospital of Lille, France
Acta Paediatr 101:e426-30. 2012..To report our 10 year experience with noradrenaline use in children with septic shock focusing on doses, routes of administration and complications...
[Evaluation of the antibiotic prescription in a paediatric intensive care unit]E Audry Degardin
Service de Réanimation Pédiatrique, hôpital Jeanne de Flandre et université de Lille II, avenue E Avinee, 59037 Lille Cedex, France
Arch Pediatr 14:157-63. 2007..The antibiotic prescription in intensive care units is frequent using often broad-spectrum antibiotics; its quality has never been evaluated in paediatric intensive care units...
[Use of midazolam for refractory status epilepticus in children]M E Lampin
Service de Réanimation Pédiatrique, CHRU de Lille, Lille Cedex, France
Rev Neurol (Paris) 166:648-52. 2010..Morbidity and mortality are high in children with refractory status epilepticus (RSE). Here, we assess the efficacy of midazolam for RSE in children...
[Incidence of invasive meningococcal diseases in children in Northern France: usefulness and limits of the discharge code database for correcting compulsory notification data]F Dubos
Service de pédiatrie générale et maladies infectieuses, pôle enfant, Hopital Jeanne de Flandre, CHRU de Lille, avenue E Avinee, 59037 Lille Cedex, France
Arch Pediatr 16:984-90. 2009..Surveillance of invasive meningococcal diseases (IMD) is based on mandatory reporting. Evaluation of the exhaustivity of the surveillance with capture-recapture analysis can correct for underreporting...
Plastic bronchitis mimicking foreign body aspiration that needs a specific diagnostic procedureO Noizet
Pediatric Intensive Care Unit, University Hospital of Lille, 59037 Lille, France
Intensive Care Med 29:329-31. 2003..We recommend the immersion in normal saline of all plugs discovered in children with predisposing diseases mainly represented by infections, allergy, acute chest syndrome, and congenital cardiopathies...
Admission plasma vasopressin levels in children with meningococcal septic shockF Leclerc
Service de Réanimation Pédiatrique, Hopital Jeanne de Flandre, avenue Eugène Aviné, 59037, Lille, France
Intensive Care Med 29:1339-44. 2003..Vasopressin (AVP) response has been reported to be inappropriately low in adult established septic shock. We studied admission AVP levels in children with meningococcal septic shock (MSS)...
[Procalcitonin in pediatric resuscitation]F Leclerc
, , CHU de Lille, 59037 Lille Cedex, France
Arch Pediatr 11:587-9. 2004
Role of viruses and atypical bacteria in exacerbations of asthma in hospitalized children: a prospective study in the Nord-Pas de Calais region (France)C Thumerelle
Department of Pediatrics, CHU Lille, Lille, France
Pediatr Pulmonol 35:75-82. 2003..Persistent clinical features were more frequently associated with atypical bacterial infections, suggesting that these infections should be investigated and treated in cases of persistent asthmatic symptoms...
[Two children with cerebral and retinal hemorrhages: do not diagnose shaken baby syndrome too rapidly]A Botte
Service de Réanimation Pédiatrique, Faculte de Medecine, Université de Lille Nord de France, Hopital Jeanne de Flandre, CHU de Lille, 54, avenue Eugene Avinee, 59037 Lille Cedex, France
Arch Pediatr 19:42-6. 2012..These 2 cases underline the need for working as a team that includes hematologists able to interpret coagulation parameters...
[Does selective digestive decontamination prevent nosocomial infections?]F Leclerc
Service de Réanimation Pédiatrique, Hopital Jeanne de Flandre, CHU de Lille, France
Arch Pediatr 11:175-9. 2004..patients mechanically ventilated for at least 48 hours) and units (excluding those where multiresistance is endemic). Obviously, surveillance of patient and unit bacterial ecology and improvement of antibiotic policy must be reinforced...
[Is there still a place for dopamine in the paediatric critical care setting?]F Leclerc
Service de Réanimation Pédiatrique, Hopital Jeanne de Flandre, Faculte de Medecine, Universite de Lille II, Lille Cedex, France
Ann Fr Anesth Reanim 26:576-80. 2007..Thus, dopamine still is part of the stock of drugs that act on the cardiocirculatory system (but for how long?)...
Molecular method for the diagnosis of imported pediatric malariaL Delhaes Jeanne
Laboratoire de parasitologie mycologie EA3609, département de microbiologie de médecine, Faculte de Medecine, Universite de Lille 2, CHU de Lille, Lille, France
Med Mal Infect 40:115-8. 2010..The major epidemiological features of imported malaria, and the difficulty to diagnose childhood severe malaria are described. The contribution of molecular methods for the diagnosis of imported malaria is discussed...
[Life-threatening Plasmodium falciparum parasitemia, in an infant returning from the tropics]P Gerardin
Réanimation Pédiatrique, Hopital Jeanne de Flandre, 2, avenue Eugene Avinee, 59037 Lille Cedex, France
Arch Pediatr 9:1260-3. 2002..CONCLUSION: In this non-immune infant, prostration and thrombopocytopenia seemed to be earlier predictors of severity than hyperparasitemia and other WHO criteria, which have not been yet validated in travelling children...
