Laurent Beghin

Summary

Affiliation: CHRU de Lille
Country: France

Publications

  1. ncbi request reprint [Technical aspects and relevance of energy expenditure and physical activity assessment in clinical research for cystic fibrosis patients]
    L Beghin
    Unité de Gastroentérologie, Hepatologie et nutrition, Centre de Ressources et de Compétences pour la Mucoviscidose, et EA 3925, Clinique de Pediatrie, Hopital Jeanne de Flandre, CHRU de Lille, Universite de Lille II, France
    Arch Pediatr 12:1139-44. 2005
  2. doi request reprint Changes in lung function in young cystic fibrosis patients between two courses of intravenous antibiotics against Pseudomonas aeruginosa
    Laurent Beghin
    EA 3925, Université Lille 2 Droit et Santé and Division of Gastroenterology, Hepatology and Nutrition, Cystic Fibrosis Center, Lille, France
    Pediatr Pulmonol 44:464-71. 2009
  3. doi request reprint Quality assurance of ethical issues and regulatory aspects relating to good clinical practices in the HELENA Cross-Sectional Study
    L Beghin
    EA 3925, Lille 2 Law and Health University Faculty of Medicine, Lille, France
    Int J Obes (Lond) 32:S12-8. 2008
  4. ncbi request reprint Impact of intravenous antibiotic therapy on total daily energy expenditure and physical activity in cystic fibrosis children with Pseudomonas aeruginosa pulmonary exacerbation
    Laurent Beghin
    Unité de Gastroentérologie, Hepatologie et nutrition, Clinique de Pediatrie, Hopital Jeanne de Flandre, 2, Avenue Oscar Lambret, 59037 Lille, France
    Pediatr Res 54:756-61. 2003
  5. pmc Dietary n-3 fatty acids have suppressive effects on mucin upregulation in mice infected with Pseudomonas aeruginosa
    Daniel Tetaert
    INSERM, U837, JPARC Research Centre, IMPRT, Place de Verdun, Lille, France
    Respir Res 8:39. 2007
  6. doi request reprint Nutritional and pubertal status influences accuracy of self-reported weight and height in adolescents: the HELENA Study
    Laurent Beghin
    U955 Inserm, IFR114, Faculty of Medicine, Universite Lille Nord de France, Lille, France
    Ann Nutr Metab 62:189-200. 2013
  7. ncbi request reprint Impact of the choice of threshold on physical activity patterns in free living conditions among adolescents measured using a uniaxial accelerometer: the HELENA study
    Jeremy Vanhelst
    a Inserm U995, IFR114, Faculty of Medicine, University Lille 2, Lille, France
    J Sports Sci 32:110-5. 2014
  8. ncbi request reprint Total energy expenditure and physical activity in children treated with home parenteral nutrition
    Laurent Beghin
    Unité de Gastroentérologie, Hepatologie et nutrition, Clinique de Pediatrie, Hopital Jeanne de Flandre, 2, Avenue Oscar Lambret, F 59037 Lille Cedex, France
    Pediatr Res 53:684-90. 2003
  9. pmc Validation of the Vivago Wrist-Worn accelerometer in the assessment of physical activity
    Jeremy Vanhelst
    centre d investigation clinique, CIC PT 9301 Inserm CH and U, 59037, Lille, France
    BMC Public Health 12:690. 2012
  10. doi request reprint Mechanical ventilatory constraints during incremental exercise in healthy and cystic fibrosis children
    Benoit Borel
    Univ Lille Nord de France, Lille, France UDSL, EA 4488, Faculte des Sciences du Sport et de l Education Physique, Ronchin, France
    Pediatr Pulmonol 49:221-9. 2014

Collaborators

Detail Information

Publications27

  1. ncbi request reprint [Technical aspects and relevance of energy expenditure and physical activity assessment in clinical research for cystic fibrosis patients]
    L Beghin
    Unité de Gastroentérologie, Hepatologie et nutrition, Centre de Ressources et de Compétences pour la Mucoviscidose, et EA 3925, Clinique de Pediatrie, Hopital Jeanne de Flandre, CHRU de Lille, Universite de Lille II, France
    Arch Pediatr 12:1139-44. 2005
    ..Precise and ambulatory assessment of energy expenditure and physical activity permit to check and adapt dietary allowances in CF. These techniques could be simultaneously used and be helpful to assess efficacy of intervention studies...
  2. doi request reprint Changes in lung function in young cystic fibrosis patients between two courses of intravenous antibiotics against Pseudomonas aeruginosa
    Laurent Beghin
    EA 3925, Université Lille 2 Droit et Santé and Division of Gastroenterology, Hepatology and Nutrition, Cystic Fibrosis Center, Lille, France
    Pediatr Pulmonol 44:464-71. 2009
    ..The aim of this study was to monitor kinetics of degradation of pulmonary and nutritional status after IVAT in CF patients...
  3. doi request reprint Quality assurance of ethical issues and regulatory aspects relating to good clinical practices in the HELENA Cross-Sectional Study
    L Beghin
    EA 3925, Lille 2 Law and Health University Faculty of Medicine, Lille, France
    Int J Obes (Lond) 32:S12-8. 2008
    ....
  4. ncbi request reprint Impact of intravenous antibiotic therapy on total daily energy expenditure and physical activity in cystic fibrosis children with Pseudomonas aeruginosa pulmonary exacerbation
    Laurent Beghin
    Unité de Gastroentérologie, Hepatologie et nutrition, Clinique de Pediatrie, Hopital Jeanne de Flandre, 2, Avenue Oscar Lambret, 59037 Lille, France
    Pediatr Res 54:756-61. 2003
    ..After IVAT, the reduction in REE is probably compensated by an increase in PA in CF patients...
  5. pmc Dietary n-3 fatty acids have suppressive effects on mucin upregulation in mice infected with Pseudomonas aeruginosa
    Daniel Tetaert
    INSERM, U837, JPARC Research Centre, IMPRT, Place de Verdun, Lille, France
    Respir Res 8:39. 2007
    ..This suggests that n-3 PUFAs may have a protective effect against mucus over-production in airway diseases. Therefore, we hypothesized that n-3 PUFAs may downregulate mucins expression...
  6. doi request reprint Nutritional and pubertal status influences accuracy of self-reported weight and height in adolescents: the HELENA Study
    Laurent Beghin
    U955 Inserm, IFR114, Faculty of Medicine, Universite Lille Nord de France, Lille, France
    Ann Nutr Metab 62:189-200. 2013
    ..The aim of this study was to assess factors that have an effect on the accuracy of self-reported weight and height in adolescents...
  7. ncbi request reprint Impact of the choice of threshold on physical activity patterns in free living conditions among adolescents measured using a uniaxial accelerometer: the HELENA study
    Jeremy Vanhelst
    a Inserm U995, IFR114, Faculty of Medicine, University Lille 2, Lille, France
    J Sports Sci 32:110-5. 2014
    ..The definition of the threshold for PA intensity may considerably affect the PA patterns in FLC when assessed using a uniaxial accelerometer and the number of participants fulfilling the recommendations...
  8. ncbi request reprint Total energy expenditure and physical activity in children treated with home parenteral nutrition
    Laurent Beghin
    Unité de Gastroentérologie, Hepatologie et nutrition, Clinique de Pediatrie, Hopital Jeanne de Flandre, 2, Avenue Oscar Lambret, F 59037 Lille Cedex, France
    Pediatr Res 53:684-90. 2003
    ..05 Spearman test). These results suggest that the energy requirements of children on long-term home parenteral nutrition programs do not differ from controls and that cyclic parenteral nutrition does not interfere with physical activity...
  9. pmc Validation of the Vivago Wrist-Worn accelerometer in the assessment of physical activity
    Jeremy Vanhelst
    centre d investigation clinique, CIC PT 9301 Inserm CH and U, 59037, Lille, France
    BMC Public Health 12:690. 2012
    ..The aim of this study was to validate the Vivago® Wrist-Worn Accelerometer at various intensities of physical activity (PA) in adults...
  10. doi request reprint Mechanical ventilatory constraints during incremental exercise in healthy and cystic fibrosis children
    Benoit Borel
    Univ Lille Nord de France, Lille, France UDSL, EA 4488, Faculte des Sciences du Sport et de l Education Physique, Ronchin, France
    Pediatr Pulmonol 49:221-9. 2014
    ..To analyze breathing pattern and mechanical ventilatory constraints during incremental exercise in healthy and cystic fibrosis (CF) children...
  11. doi request reprint A favorable built environment is associated with better physical fitness in European adolescents
    Jeremy Vanhelst
    INSERM U995, University Lille Nord de France, Lille, France CIC PT 9301 INSERM CH and U, University Hospital, Lille, France Electronic address
    Prev Med 57:844-9. 2013
    ..To assess the association between the built environment and physical fitness and physical activity in adolescents...
  12. ncbi request reprint The six-minute walk test in obese youth: reproducibility, validity, and prediction equation to assess aerobic power
    Jeremy Vanhelst
    CIC PT 9301 Inserm CH and U of Lille, CHRU of Lille, Lille, France
    Disabil Rehabil 35:479-82. 2013
    ..38 × BMI (kg/m((2))). Conclusions: In obese youth, the 6 MWT is a reproducible and valid test for assessing aerobic power. A prediction equation was developed to estimate VO(2)max, using distance walked in 6MWT and BMI. [Box: see text]...
  13. doi request reprint New validated thresholds for various intensities of physical activity in adolescents using the Actigraph accelerometer
    Jeremy Vanhelst
    INSERM U995, Faculte de Medecine, Universite, Lille 2 Droit et Santé et IMPRT, Lille, France
    Int J Rehabil Res 34:175-7. 2011
    ..This study establishes new threshold values for various physical activities that can be used for population-based studies in adolescents...
  14. ncbi request reprint Resting energy expenditure in children with neonatal chronic lung disease and obstruction of the airways
    Lucile Bott
    EA 3925, IFR 114, Universite de Lille 2, Clinique de Pediatrie, Hopital Jeanne de Flandre, Lille, France
    Br J Nutr 98:796-801. 2007
    ..This supports the hypothesis that body composition and pulmonary function in BPD in later childhood are fixed sequelae originating from the neonatal period...
  15. ncbi request reprint Influence of esophageal pH recording on physical activity in children
    Laurent Michaud
    Division of Gastroenterology, Hepatology, Lille University Children s Hospital and EA 3925, IFR 114, Lille University 2, Lille, France
    J Pediatr Gastroenterol Nutr 48:426-30. 2009
    ..The aim of this study was to assess the influence of ambulatory esophageal pH recording on physical activity in children...
  16. pmc Genetic and molecular insights into the role of PROX1 in glucose metabolism
    Sophie Lecompte
    INSERM U744, Institut Pasteur de Lille, Universite Lille Nord de France, UDSL, Lille, France
    Diabetes 62:1738-45. 2013
    ..All together, we propose that reduced expression of PROX1 by cis-regulatory variants results in altered β-cell insulin secretion and thereby confers susceptibility to type 2 diabetes...
  17. pmc Comparison of two ActiGraph accelerometer generations in the assessment of physical activity in free living conditions
    Jeremy Vanhelst
    centre d investigation clinique, CIC PT 9301 Inserm CH and U, Lille, France
    BMC Res Notes 5:187. 2012
    ..The aim of this study was to compare physical activity measured using GT1M ActiGraph and GT3X ActiGraph accelerometers in free living conditions...
  18. pmc Main characteristics and participation rate of European adolescents included in the HELENA study
    Laurent Beghin
    INSERM U955, IFR 114 IMPRT, Faculty of Medicine, Universite Lille Nord de France, F 59037, Lille, France
    Arch Public Health 70:14. 2012
    ..abstract:..
  19. pmc Comparison of uniaxial and triaxial accelerometry in the assessment of physical activity among adolescents under free-living conditions: the HELENA study
    Jeremy Vanhelst
    INSERM U995, IFR114, Faculty of Medicine, University Lille 2, Lille, France
    BMC Med Res Methodol 12:26. 2012
    ..The aim of this study was to compare physical activity (PA) levels and patterns obtained simultaneously by triaxial accelerometry and uniaxial accelerometry in adolescents in free-living conditions...
  20. doi request reprint Associations between common genetic polymorphisms in the liver X receptor alpha and its target genes with the serum HDL-cholesterol concentration in adolescents of the HELENA Study
    Vanessa Legry
    INSERM, U744, Institut Pasteur de Lille, Univ Lille Nord de France, UDSL, Lille, France
    Atherosclerosis 216:166-9. 2011
    ..Genetic variability in the NR1H3 gene (encoding LXRα) and in several of its target genes is associated with serum HDL-cholesterol (HDL-C) concentrations. We sought to assess if these associations could be detected in adolescents...
  21. pmc A conative educational model for an intervention program in obese youth
    Jeremy Vanhelst
    centre d investigation clinique, CIC PT 9301 Inserm CH and U, Lille, France
    BMC Public Health 12:416. 2012
    ..The aim of this study was to assess changes in body mass index, the ability to perform sport activities, behavior in the classroom and academic performance following one year of a health-wellness intervention program in obese youth...
  22. doi request reprint Comparison of mechanical ventilatory constraints between continuous and intermittent exercises in healthy prepubescent children
    Benoit Borel
    Univ Lille Nord de France, Lille, France
    Pediatr Pulmonol 46:785-94. 2011
    ..The aim of this study was to evaluate the occurrence and severity of mechanical ventilatory constraints in healthy prepubescent children during continuous and intermittent exercise...
  23. ncbi request reprint Add-on omalizumab in children with severe allergic asthma: a 1-year real life survey
    Antoine Deschildre
    pôle enfant, Clinique de Pédiatrie Jeanne de Flandre, CHRU de Lille, Université Nord de France, Lille
    Eur Respir J 42:1224-33. 2013
    ..Omalizumab improved asthma control in children with severe allergic asthma and was generally well tolerated. The observed benefit was greater than that reported in clinical trials...
  24. pmc Effect of child health status on parents' allowing children to participate in pediatric research
    Jeremy Vanhelst
    centre d investigation clinique, CIC PT 9301 Inserm CH and U, Lille, 59037, France
    BMC Med Ethics 14:7. 2013
    ..To identify motivational factors linked to child health status that affected the likelihood of parents' allowing their child to participate in pediatric research...
  25. doi request reprint Effect of multifibre mixture with prebiotic components on bifidobacteria and stool pH in tube-fed children
    Dominique Guimber
    Unité de Nutrition Artificielle à Domicile, CHU Lille, Lille, France
    Br J Nutr 104:1514-22. 2010
    ..In conclusion, addition of a multifibre mixture with prebiotic components to paediatric EN is well tolerated, promotes bifidobacteria and reduces stool pH, indicating an improved gut health...
  26. ncbi request reprint Omega-3 polyunsaturated fatty acids improve host response in chronic Pseudomonas aeruginosa lung infection in mice
    Maud Pierre
    Faculte de Medecine, Hopital Jeanne de Flandre, Université de Lille and CHRU de Lille, France
    Am J Physiol Lung Cell Mol Physiol 292:L1422-31. 2007
    ..This work suggests that a better control of the omega-6/omega-3 PUFA balance may represent an interesting target in the prevention and/or control of P. aeruginosa infection in patients...
  27. pmc Breast-feeding modulates the influence of the peroxisome proliferator-activated receptor-gamma (PPARG2) Pro12Ala polymorphism on adiposity in adolescents: The Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA) cross-sectional study
    Caroline Verier
    INSERM, U995, Institut Fédératif de Recherche 114, Faculte de Medecine, Université Droit et Santé de Lille, Lille, France
    Diabetes Care 33:190-6. 2010
    ..The objectives of this study were to assess 1) the influence of the PPARG2 Pro12Ala polymorphism on adiposity markers in adolescents and 2) a possible modulating effect of breast-feeding on these associations...