Research Topics
| Valerie ChetboulSummaryCountry: France Publications
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Publications
[Doppler myocardial tissue imaging: a new promising echocardiographic technique]V Chetboul
Unité de Cardiologie d Alfort, Ecole Nationale Veterinaire d Alfort, France
Schweiz Arch Tierheilkd 145:416-23. 2003..TDI might therefore be used as an accurate technique for screening cardiomyopathies, and could also represent in the next future a useful tool for evaluating the efficacy of early cardiac therapeutic interventions...- Retrospective study of 156 atrial septal defects in dogs and cats (2001-2005)V Chetboul
Pharmacy Toxicology Unit of Alfort, INSERM U660, National Veterinary School of Alfort, 7 Avenue du General de Gaulle, 94704 Maisons Alfort cedex, France
J Vet Med A Physiol Pathol Clin Med 53:179-84. 2006..ASD should be suspected, for example, in instances of left basal systolic heart murmur, although its clinical and haemodynamic consequences are usually minor... 
Within-day and between-day variability of transthoracic anatomic M-mode echocardiography in the awake bottlenose dolphin (Tursiops truncatus)Valerie Chetboul
Universite Paris Est, Ecole Nationale Veterinaire d Alfort, Unité de Cardiologie d Alfort UCA, Centre Hospitalier Universitaire Vétérinaire d Alfort CHUVA, 7 Avenue du General de Gaulle, 94704 Maisons Alfort cedex, France INSERM, U955, Equipe 03, 51 Avenue du Marechal de Lattre de Tassigny, 94010 Creteil Cedex, France Electronic address
J Vet Cardiol 14:511-8. 2012..Further studies are required to determine the corresponding reference intervals...- Prospective echocardiographic and tissue Doppler screening of a large Sphynx cat population: Reference ranges, heart disease prevalence and genetic aspectsValerie Chetboul
Universite Paris Est, Ecole Nationale Veterinaire d Alfort, Unité de Cardiologie d Alfort UCA, Centre Hospitalier Universitaire Vétérinaire d Alfort CHUVA, 7 Avenue du General de Gaulle, 94704 Maisons Alfort cedex, France INSERM, U955, Equipe 03, 51 Avenue du Marechal de Lattre de Tassigny, 94010 Creteil Cedex, France Electronic address
J Vet Cardiol 14:497-509. 2012.... - Echocardiographic assessment of canine degenerative mitral valve diseaseValerie Chetboul
Universite Paris Est, Ecole Nationale Veterinaire d Alfort, Unité de Cardiologie d Alfort UCA, Centre Hospitalier Universitaire Vétérinaire d Alfort CHUVA, 7 Avenue du General de Gaulle, 94704 Maisons Alfort cedex, France
J Vet Cardiol 14:127-48. 2012.... - Quantitative assessment of regional right ventricular myocardial velocities in awake dogs by Doppler tissue imaging: repeatability, reproducibility, effect of body weight and breed, and comparison with left ventricular myocardial velocitiesValerie Chetboul
Unité de Cardiologie d Alfort, Ecole Nationale Veterinaire d Alfort, 7 Avenue du General de Gaulle, 94704 Maisons Alfort, France
J Vet Intern Med 19:837-44. 2005..These data also demonstrate the heterogeneity of the myocardial velocities between the left and the right ventricles and between the base and the apex... - Two-dimensional color tissue Doppler imaging detects myocardial dysfunction before occurrence of hypertrophy in a young Maine Coon catValerie Chetboul
Cardiology Unit of Alfort National Veterinary School of Alfort, 7 Avenue du General de Gaulle, 94 704 Maisons Alfort cedex, France
Vet Radiol Ultrasound 47:295-300. 2006..This report demonstrates for the first time in spontaneous HCM the sensitivity of TDI for early diagnosis of myocardial dysfunction and suggests that TDI should form part of the screening techniques for early diagnosis of feline HCM... - Tissue Doppler imaging for detection of radial and longitudinal myocardial dysfunction in a family of cats affected by dystrophin-deficient hypertrophic muscular dystrophyValerie Chetboul
Cardiology Unit of Alfort, INSERM U660, National Veterinary School of Alfort, Maisons Alfort, France
J Vet Intern Med 20:640-7. 2006..TDI consistently detects LVFW dysfunction in cats with HFMD despite the absence of myocardial hypertrophy. Therefore, TDI appears more sensitive than conventional echocardiography in detecting regional myocardial abnormalities... - Congenital heart diseases in the boxer dog: A retrospective study of 105 cases (1998-2005)V Chetboul
Cardiology Unit of Alfort, National Veterinary School of Alfort, 7 Avenue du General de Gaulle, 94704 Maisons Alfort cedex, France
J Vet Med A Physiol Pathol Clin Med 53:346-51. 2006..This confirms that the detection of such a murmur should not be used as the unique criterion for diagnostic confirmation of SAS... - Ultrasonographic assessment of regional radial and longitudinal systolic function in healthy awake dogsValerie Chetboul
Unité de Cardiologie d Alfort, INSERM U660 National Institute of Health and Medical Research, Ecole Nationale Veterinaire d Alfort, Maisons Alfort, France
J Vet Intern Med 20:885-93. 2006..Strain (St) and strain rate (SR) imaging are new ultrasound modalities based on tissue Doppler imaging (TDI) that allow quantitative assessment of segmental myocardial contraction or stretching and rate of deformation, respectively... - Assessment of regional systolic and diastolic myocardial function using tissue Doppler and strain imaging in dogs with dilated cardiomyopathyValerie Chetboul
Unité de Cardiologie d Alfort, Ecole Nationale Veterinaire d Alfort, 7 Avenue du General de Gaulle, 94 704 Maisons Alfort, France
J Vet Intern Med 21:719-30. 2007..Analysis of TDI and St features in dogs with overt DCM is a prerequisite before using these new criteria in prospective screenings of predisposed families or in clinical trials... - Comparative adverse cardiac effects of pimobendan and benazepril monotherapy in dogs with mild degenerative mitral valve disease: a prospective, controlled, blinded, and randomized studyValerie Chetboul
Unité de Cardiologie d Alfort, Ecole Nationale Veterinaire d Alfort, 7 Avenue du General de Gaulle, 94 704 Maisons Alfort, France
J Vet Intern Med 21:742-53. 2007..Pimobendan (PIMO) is an inodilator that may have some beneficial effects in canine degenerative mitral valve disease (MVD). However, little information is available about its cardiac effects in dogs without systolic myocardial dysfunction... - Radial strain and strain rate by two-dimensional speckle tracking echocardiography and the tissue velocity based technique in the dogValerie Chetboul
Unité de Cardiologie d Alfort, Ecole Nationale Veterinaire
J Vet Cardiol 9:69-81. 2007.... - Noninvasive assessment of systolic left ventricular torsion by 2-dimensional speckle tracking imaging in the awake dog: repeatability, reproducibility, and comparison with tissue Doppler imaging variablesV Chetboul
Unité de Cardiologie d Alfort, Ecole Nationale Veterinaire d Alfort, 94 704 Maisons Alfort cedex, France
J Vet Intern Med 22:342-50. 2008..However, it has never been assessed in the awake dog, because magnetic resonance imaging and sonomicrometry have been the only methods available so far... - Association of plasma N-terminal pro-B-type natriuretic peptide concentration with mitral regurgitation severity and outcome in dogs with asymptomatic degenerative mitral valve diseaseV Chetboul
Unité de Cardiologie d Alfort, Ecole Nationale Veterinaire d Alfort, 7 Avenue du General de Gaulle, 94704 Maisons Alfort, Cedex, France
J Vet Intern Med 23:984-94. 2009.... - Advanced techniques in echocardiography in small animalsValerie Chetboul
Unité de Cardiologie d Alfort, Ecole Nationale Veterinaire d Alfort, Maisons Alfort Cedex, France
Vet Clin North Am Small Anim Pract 40:529-43. 2010..An outline of these 4 recent ultrasound techniques, their impact on the understanding of right and left ventricular function in small animals, and their application in research and clinical settings are given in this article... 
[Epidemiological, clinical, echo-doppler characteristics of mitral valve endocardiosis in Cavalier King Charles in France: a retrospective study of 451 cases (1995 to 2003)]Valerie Chetboul
Unité de Cardiologie d Alfort, Ecole Nationale Veterinaire d Alfort, 7, avenue du Général de Gaulle 94, 704 Maisons Alfort Cedex, France
Can Vet J 45:1012-5. 2004..Mitral valve endocardiosis represented 93.3% of the ultrasonographic abnormalities...- Comparison of Doppler ultrasonography and high-definition oscillometry for blood pressure measurements in healthy awake dogsValerie Chetboul
Unité de Cardiologie d Alfort, Unité Mixte de Recherche INSERM U955, Ecole Nationale Veterinaire d Alfort, 94 704 Maisons Alfort cedex, France
Am J Vet Res 71:766-72. 2010..To determine the intra- and interobserver variability of systolic arterial pressure (SAP) and diastolic arterial pressure (DAP) measurements obtained with 2 indirect methods in awake dogs and percentage of successful measurements... - Tissue Doppler imaging detects early asymptomatic myocardial abnormalities in a dog model of Duchenne's cardiomyopathyValerie Chetboul
INSERM E0001, Kremlin Bicetre, France
Eur Heart J 25:1934-9. 2004..We sought to determine whether tissue Doppler imaging (TDI) could detect early alteration in myocardial function in a dog model of Duchenne muscular dystrophy, i.e. the Golden Retriever Muscular Dystrophy (GRMD)... - [Congenital malformations of the tricuspid valve in domestic carnivores: a retrospective study of 50 cases]V Chetboul
Unité de Cardiologie d Alfort, Ecole Nationale Veterinaire d Alfort, Maisons Alfort, France
Schweiz Arch Tierheilkd 146:265-75. 2004..Last, the prognosis of RAVM was worsened by atrial fibrillation and right-sided heart failure... - Diagnostic potential of natriuretic peptides in the occult phase of golden retriever muscular dystrophy cardiomyopathyValerie Chetboul
Unité de Cardiologie d Alfort, Ecole Nationale Veterinaire d Alfort, Maisons Alfort, France
J Vet Intern Med 18:845-50. 2004..However, this peptide does not allow very early detection because its optimal discriminatory power was observed in adult dogs (ie, > or =12 months of age)... - [Specific features of echocardiographic examination in ophidians]V Chetboul
Unité de Cardiologie d Alfort, ENVA, Maisons Alfort, France
Schweiz Arch Tierheilkd 146:327-34. 2004..The main purpose of this technique is to establish the ante-mortem diagnosis of heart diseases, such as endocarditis and myocarditis... - Doppler echocardiography-derived evidence of pulmonary arterial hypertension in dogs with degenerative mitral valve disease: 86 cases (2001-2005)François J Serres
Unité de Cardiologie d Alfort, Ecole Nationale Vétérinaire d Alfort Institution, 7 Avenue du General de Gaulle, 94704 Maisons Alfort cedex, France
J Am Vet Med Assoc 229:1772-8. 2006.... - Tissue Doppler assessment of diastolic and systolic alterations of radial and longitudinal left ventricular motions in Golden Retrievers during the preclinical phase of cardiomyopathy associated with muscular dystrophyValerie Chetboul
Unité de Cardiologie d Alfort, Ecole Nationale Veterinaire d Alfort, 7 Avenue du General de Gaulle, 94704 Maisons Alfort, France
Am J Vet Res 65:1335-41. 2004..To quantify radial and longitudinal left ventricular free wall (LVFW) velocities in dogs during the preclinical phase of Golden Retriever muscular dystrophy (GRMD)-associated cardiomyopathy by use of tissue Doppler imaging (TDI)... - Azotemia in cats with feline hypertrophic cardiomyopathy: prevalence and relationships with echocardiographic variablesVassiliki Gouni
Unité de Cardiologie d Alfort, Ecole Nationale Veterinaire d Alfort, Maisons Alfort Cedex, France
J Vet Cardiol 10:117-23. 2008.... - Plasma N-terminal pro-B-type natriuretic peptide concentration helps to predict survival in dogs with symptomatic degenerative mitral valve disease regardless of and in combination with the initial clinical status at admissionFrancois Serres
Unité de Cardiologie d Alfort, Ecole Nationale Veterinaire d Alfort, 7 Avenue du General de Gaulle, 94704 Maisons Alfort cedex, France
J Vet Cardiol 11:103-21. 2009..The aim of this study was to evaluate the comparative ability of N-terminal pro-B-type natriuretic peptide plasma concentration (NT-proBNP) and various echocardiographic variables to predict outcome in dogs with MVD... - Quantification of mitral valve regurgitation in dogs with degenerative mitral valve disease by use of the proximal isovelocity surface area methodVassiliki Gouni
Unité de Cardiologie d Alfort, Ecole Nationale Veterinaire d Alfort, 7 Avenue du General de Gaulle, F 94 704 Maisons Alfort cedex, France
J Am Vet Med Assoc 231:399-406. 2007.... - Azotemia and glomerular filtration rate in dogs with chronic valvular diseaseAudrey P Nicolle
Unité de Cardiologie d Alfort and INSERM U660, National Veterinary School, 7 Avenue du General de Gaulle, F94704 Maisons Alfort Cedex, France
J Vet Intern Med 21:943-9. 2007..Little information is available about the prevalence of renal dysfunction in dogs with chronic valvular heart disease (CVD)... - Quantitative assessment of velocities of the annulus of the left atrioventricular valve and left ventricular free wall in healthy cats by use of two-dimensional color tissue Doppler imagingValerie Chetboul
Cardiology Unit of Alfort, National Veterinary School of Alfort, , 94704 Maisons-Alfort Cedex, France
Am J Vet Res 67:250-8. 2006..These indices could complement conventional analysis of left ventricular function and contribute to the early accurate detection of cardiomyopathy in cats... - Chordae tendineae rupture in dogs with degenerative mitral valve disease: prevalence, survival, and prognostic factors (114 cases, 2001-2006)Francois Serres
Unité de Cardiologie d Alfort, Ecole Nationale Veterinaire d Alfort, Maisons Alfort, France
J Vet Intern Med 21:258-64. 2007..The survival time and prognostic factors predictive of survival in dogs with CTR remain unknown... - Quantification, repeatability, and reproducibility of feline radial and longitudinal left ventricular velocities by tissue Doppler imagingValerie Chetboul
Unité de Cardiologie d Alfort, Ecole Nationale Veterinaire d Alfort, 7 Avenue du General de Gaulle, 94 704 Maisons Alfort cedex, France
Am J Vet Res 65:566-72. 2004..To measure the radial and longitudinal velocities of several myocardial segments of the left ventricular wall by use of tissue Doppler imaging (TDI) in healthy cats and determine the repeatability and reproducibility of the technique... - Use of tissue Doppler imaging to confirm the diagnosis of dilated cardiomyopathy in a dog with equivocal echocardiographic findingsValerie Chetboul
Unité de cardiologie, Ecole Nationale Veterinaire d Alfort, 7 Avenue du General de Gaulle, 94704 Maisons Alfort, France
J Am Vet Med Assoc 225:1877-80, 1864. 2004..In dogs with equivocal conventional echocardiographic findings of DCM, severe myocardial alterations may be detected via tissue Doppler imaging and this technique may enable early diagnosis of radial myocardial dysfunction... - Assessment of repeatability, reproducibility, and effect of anesthesia on determination of radial and longitudinal left ventricular velocities via tissue Doppler imaging in dogsValerie Chetboul
, , 7 Avenue du General de Gaulle, 94704 Maisons-Alfort Cedex, France
Am J Vet Res 65:909-15. 2004..General anesthesia improved repeatability of the procedure but cannot be recommended because it induces a decrease in myocardial velocities... - Diagnostic value of echo-Doppler and tissue Doppler imaging in dogs with pulmonary arterial hypertensionFrancois Serres
Unité de Cardiologie d Alfort, Ecole Nationale Veterinaire d Alfort, 7 Avenue du General de Gaulle, 94704 Maisons Alfort, France
J Vet Intern Med 21:1280-9. 2007..Diagnosis of pulmonary arterial hypertension (PAH) relies on Doppler measurement of pulmonic and tricuspid regurgitation (TR). However, these are not always detectable... - Quantification of pulmonary to systemic flow ratio by a Doppler echocardiographic method in the normal dog: Repeatability, reproducibility, and reference rangesFrancois Serres
Unité de Cardiologie d Alfort, Ecole Nationale Veterinaire d Alfort, 7 Avenue du General de Gaulle, 94 704 Maisons Alfort cedex, France
J Vet Cardiol 11:23-9. 2009..To determine if the pulmonary to systemic flow ratio (Qp/Qs) could be assessed in healthy awake dogs using Doppler echocardiography... - Familial aortic aneurysm in Leonberg dogsValerie Chetboul
Unité de Cardiologic d Alfort, Ecole Nationale Veterinaire d Alfort, 94704 Maisons Alfort cedex, France
J Am Vet Med Assoc 223:1159-62, 1129. 2003..The sire and 1 male littermate also had an aneurysm of the ascending aorta. To the authors' knowledge, this is the first report of familial aortic aneurysm in dogs... - Quadricuspid aortic valve and associated abnormalities in the dog: report of six casesFrancois Serres
Cardiology Unit of Alfort, National Veterinary School of Alfort, 7 Avenue du General de Gaulle, 94 704 Maisons Alfort cedex, France
J Vet Cardiol 10:25-31. 2008..To describe the clinical and echocardiographic findings in dogs with quadricuspid aortic valve (QAV)... - Echoguided closed commissurotomy for mitral valve stenosis in a dogEmilie Tréhiou-Sechi
Unité de Cardiologie d Alfort, CHUVA, Ecole Nationale Veterinaire d Alfort, Maisons Alfort Cedex, France
J Vet Cardiol 13:219-25. 2011..Thirteen months after surgery the dog is still doing well with resolution of ascites and a marked improvement of most echo-Doppler variables... - Ante-mortem diagnosis of persistent truncus arteriosus in an 8-year-old asymptomatic dogFrancois Serres
Unité de Cardiologie d Alfort, National Veterinary School of Alfort, 7 Avenue du General de Gaulle, 94 704 Maisons Alfort cedex, France
J Vet Cardiol 11:59-65. 2009..This case is also of interest because of the age of the animal and the total absence of cardio-respiratory signs at the time of diagnosis... - Spontaneous feline hypertension: clinical and echocardiographic abnormalities, and survival rateValerie Chetboul
Unité de Cardiologie d Alfort, Ecole Nationale Veterinaire d Alfort, Maisons Alfort, France
J Vet Intern Med 17:89-95. 2003..Further prospective studies are needed to clearly identify the factors involved in survival time in hypertensive cats... - Bradykinin restores left ventricular function, sarcomeric protein phosphorylation, and e/nNOS levels in dogs with Duchenne muscular dystrophy cardiomyopathyJin Bo Su
INSERM U955, ENVA, 7 avenu du Général de Gaulle, Maisons Alfort, France
Cardiovasc Res 95:86-96. 2012..Therefore, the goals of this research were to characterize dystrophin-deficiency cardiomyopathy and to examine cardiac effects of bradykinin in GRMD dogs... - Induction of chronic cardiac insufficiency by arteriovenous fistula and doxorubicin administrationDominique Tessier
Cardiology Unit, National Veterinary School of Alfort, France
J Card Surg 18:307-11. 2003..Depending of the dose of doxorubicin, it is possible to obtain a model of heart dilatation and ventricular hypokinesia with or without clinical symptoms of HF, with a different mortality... - Increased mitral valve regurgitation and myocardial hypertrophy in two dogs with long-term pimobendan therapyR Tissier
Unité Pédagogique de Pharmacie Toxicologie, Ecole Nationale Veterinaire d Alfort, Maisons Alfort, France
Cardiovasc Toxicol 5:43-51. 2005..We also suggest that pimobendan may induce ventricular hypertrophy. However, prospective studies are needed to confirm this observation... - Reversible pulmonary hypertension presenting simultaneously with an atrial septal defect and angiostrongylosis in a dogI Esteves
Unité de Médecine interne, National Veterinary School of Alfort, 7 Avenue du General de Gaulle, France
J Small Anim Pract 45:206-9. 2004..Eighteen months later, clinical and Doppler echocardiographic examinations were normal... - Comparison of 3 ultrasound methods for quantifying left ventricular systolic function: correlation with disease severity and prognostic value in dogs with mitral valve diseaseF Serres
Unité de Cardiologie d Alfort, Ecole Nationale Veterinaire d Alfort, Maisons Alfort Cedex, France
J Vet Intern Med 22:566-77. 2008..End-systolic volume index (ESVI) is a marker of systolic function, which can be assessed by the geometric (GM, based on Teichholz formula) or 2 planimetric methods (PM, Simpson's derived and length area methods)... - [Exploration of a third degree atrioventricular block by standard echocardiography, tissue Doppler imaging, and treatment with a cardiac pacemaker in a German wire-haired pointer]A Nicolle
Unité de Cardiologie d Alfort, Ecole Nationale Veterinaire d Alfort, Maisons Alfort, France
Schweiz Arch Tierheilkd 146:81-7. 2004.... - What is your diagnosis? Tricuspid valve stenosis (TS)A Nicolle
Unité de Cardiologie d Alfort, Ecole Nationale Veterinaire d Alfort, 7 Avenue du General de Gaulle, 94704 Maisons Alfort cedex, France
J Small Anim Pract 46:157-8. 2005 - Persistent truncus arteriosus in a 6-year-old catA P Nicolle
, , , 94-704 Maison-Alfort cedex, France
J Vet Med A Physiol Pathol Clin Med 52:350-3. 2005..The lesion was identified as a type I (TA). This case is of interest because it is the first reported echo-Doppler description of such a malformation in felines, and because of the age of the cat at the time of diagnosis... - Echocardiographic and Doppler diagnosis: first case of atrial septal aneurysm in a catA P Nicolle
Cardiology Unit of Alform, National Veterinary School of Alfort, , 94 704 Maisons-Alfort cedex, France
Vet Radiol Ultrasound 46:230-3. 2005..ASA is a rare malformation and, as in this cat, it generally occurs concomitantly with congenital or acquired heart disease and may be explained by greater pressure in one atrium, leading to controlateral protrusion of the atrial septum... - Prospective echocardiographic and tissue Doppler imaging screening of a population of Maine Coon cats tested for the A31P mutation in the myosin-binding protein C gene: a specific analysis of the heterozygous statusC Carlos Sampedrano
Unité de Cardiologie d Alfort, Maisons Alfort, France
J Vet Intern Med 23:91-9. 2009..However, the close correlation between genotype and phenotype (left ventricular hypertrophy [LVH] and dysfunction) has never been assessed in a large population, particularly in heterozygous (Hetero) cats... - Effects of inter- and intra-observer variability on echocardiographic measurements in awake catsV Chetboul
, , , 94 704 Maisons-Alfort cedex, France
J Vet Med A Physiol Pathol Clin Med 50:326-31. 2003..e. the associate professor in cardiology). A significant interaction between cat and observer was also evidenced. Thus, the most competent observer could not be replaced by any of the other observers... - Effect of benazepril on survival and cardiac events in dogs with asymptomatic mitral valve disease: a retrospective study of 141 casesJ L Pouchelon
Unité de Cardiologie d Alfort, Maisons Alfort, Cedex, France
J Vet Intern Med 22:905-14. 2008..However, their effects on asymptomatic heart disease remain controversial... - [Transesophageal echocardiography: principles, technique and potential indications in veterinary medicine]V Chetboul
Unité de Cardiologie d Alfort, Ecole Nationale Veterinaire d Alfort, France
Schweiz Arch Tierheilkd 146:321-6. 2004.... - Efficacy of oral tadalafil, a new long-acting phosphodiesterase-5 inhibitor, for the short-term treatment of pulmonary arterial hypertension in a dogF Serres
, , 94 704 Maisons-Alfort cedex, France
J Vet Med A Physiol Pathol Clin Med 53:129-33. 2006..However, long-term studies with a large number of diseased animals are now required before prescription by general practitioners could be recommended...