Frederic Charlotte

Summary

Country: France

Publications

  1. ncbi request reprint Ocular adnexal marginal zone B cell lymphoma: a clinical and pathologic study of 23 cases
    Frederic Charlotte
    Department of Pathology, Service d Anatomie Pathologique, Hopital Pitie Salpetriere, Boulevard de l Hopital, Paris, France
    Virchows Arch 448:506-16. 2006
  2. ncbi request reprint Serum biochemical markers accurately predict liver fibrosis in HIV and hepatitis C virus co-infected patients
    Robert P Myers
    Department of Hepatology and Gastroenterology, hôpital La Pitié Salpêtrière, Paris, France
    AIDS 17:721-5. 2003
  3. ncbi request reprint A prospective analysis of the prognostic value of biomarkers (FibroTest) in patients with chronic hepatitis C
    Yen Ngo
    Service d Hepato Gastroenterologie, Groupe Hospitalier Pitie Salpetriere, CNRS, Paris, France
    Clin Chem 52:1887-96. 2006
  4. pmc Diagnostic value of biochemical markers (NashTest) for the prediction of non alcoholo steato hepatitis in patients with non-alcoholic fatty liver disease
    Thierry Poynard
    Hepato Gastroenterology, AP HP Groupe Hospitalier Pitié Salpétrière, Paris, France
    BMC Gastroenterol 6:34. 2006
  5. ncbi request reprint Biochemical markers of liver fibrosis: a comparison with historical features in patients with chronic hepatitis C
    Robert P Myers
    Department of Hepato Gastroenterology, hôpital La Pitié Salpêtrière, Paris, France
    Am J Gastroenterol 97:2419-25. 2002
  6. doi request reprint Liver biopsy analysis has a low level of performance for diagnosis of intermediate stages of fibrosis
    Thierry Poynard
    Assistance Publique Hopitaux de Paris, Université Pierre et Marie Curie Liver Center, Paris, France
    Clin Gastroenterol Hepatol 10:657-63.e7. 2012
  7. doi request reprint A systematic review of follow-up biopsies reveals disease progression in patients with non-alcoholic fatty liver
    Raluca Pais
    Universite Pierre et Marie Curie, Assistance Publique Hopitaux de Paris, Hopital Pitie Salpetriere, Paris, France
    J Hepatol 59:550-6. 2013
  8. doi request reprint Long-term efficacy of rosiglitazone in nonalcoholic steatohepatitis: results of the fatty liver improvement by rosiglitazone therapy (FLIRT 2) extension trial
    Vlad Ratziu
    Hopital Pitie Salpetriere, Service d Hepatogastroenterologie, Universite Pierre et Marie Curie Paris VI, Assistance Publique Hopitaux de Paris, France
    Hepatology 51:445-53. 2010
  9. ncbi request reprint Biochemical markers of fibrosis in patients with chronic hepatitis C: a comparison with prothrombin time, platelet count, and age-platelet index
    Robert P Myers
    Department of Gastroenterology and Hepatology, Groupe Hospitalier Pitie Salpetriere, Paris, France
    Dig Dis Sci 48:146-53. 2003
  10. ncbi request reprint Cryoglobulinemia is associated with steatosis and fibrosis in chronic hepatitis C
    David Saadoun
    Service de Médecine Interne and CNRS UMR 7087, Hopital Pitie Salpetriere, Paris, France
    Hepatology 43:1337-45. 2006

Detail Information

Publications42

  1. ncbi request reprint Ocular adnexal marginal zone B cell lymphoma: a clinical and pathologic study of 23 cases
    Frederic Charlotte
    Department of Pathology, Service d Anatomie Pathologique, Hopital Pitie Salpetriere, Boulevard de l Hopital, Paris, France
    Virchows Arch 448:506-16. 2006
    ....
  2. ncbi request reprint Serum biochemical markers accurately predict liver fibrosis in HIV and hepatitis C virus co-infected patients
    Robert P Myers
    Department of Hepatology and Gastroenterology, hôpital La Pitié Salpêtrière, Paris, France
    AIDS 17:721-5. 2003
    ..Our aim was to determine the operating characteristics of a non-invasive index of biochemical markers for the prediction of fibrosis in patients with HIV/HCV co-infection...
  3. ncbi request reprint A prospective analysis of the prognostic value of biomarkers (FibroTest) in patients with chronic hepatitis C
    Yen Ngo
    Service d Hepato Gastroenterologie, Groupe Hospitalier Pitie Salpetriere, CNRS, Paris, France
    Clin Chem 52:1887-96. 2006
    ..We compared the 5-year prognostic value of the FibroTest with biopsy staging for predicting cirrhosis decompensation and survival in patients with chronic HCV infection...
  4. pmc Diagnostic value of biochemical markers (NashTest) for the prediction of non alcoholo steato hepatitis in patients with non-alcoholic fatty liver disease
    Thierry Poynard
    Hepato Gastroenterology, AP HP Groupe Hospitalier Pitié Salpétrière, Paris, France
    BMC Gastroenterol 6:34. 2006
    ..The aim was to develop and validate a new biomarker of non alcoholic steato hepatitis (NASH) the NashTest (NT) in patients with NAFLD...
  5. ncbi request reprint Biochemical markers of liver fibrosis: a comparison with historical features in patients with chronic hepatitis C
    Robert P Myers
    Department of Hepato Gastroenterology, hôpital La Pitié Salpêtrière, Paris, France
    Am J Gastroenterol 97:2419-25. 2002
    ..The aims of this study were: 1) to compare an index of five biochemical markers with historical features; and 2) to determine the utility of combining these features with the five-marker index for the prediction of significant fibrosis...
  6. doi request reprint Liver biopsy analysis has a low level of performance for diagnosis of intermediate stages of fibrosis
    Thierry Poynard
    Assistance Publique Hopitaux de Paris, Université Pierre et Marie Curie Liver Center, Paris, France
    Clin Gastroenterol Hepatol 10:657-63.e7. 2012
    ..We investigated whether this controversy results from limitations of biopsy analysis for intermediate-stage fibrosis and inappropriate determination of the standard area under the receiver-operator characteristic curve (AUROC)...
  7. doi request reprint A systematic review of follow-up biopsies reveals disease progression in patients with non-alcoholic fatty liver
    Raluca Pais
    Universite Pierre et Marie Curie, Assistance Publique Hopitaux de Paris, Hopital Pitie Salpetriere, Paris, France
    J Hepatol 59:550-6. 2013
    ..e., steatosis alone or with mild inflammation not qualifying for steatohepatitis) can evolve towards steatohepatitis (NASH) with fibrosis...
  8. doi request reprint Long-term efficacy of rosiglitazone in nonalcoholic steatohepatitis: results of the fatty liver improvement by rosiglitazone therapy (FLIRT 2) extension trial
    Vlad Ratziu
    Hopital Pitie Salpetriere, Service d Hepatogastroenterologie, Universite Pierre et Marie Curie Paris VI, Assistance Publique Hopitaux de Paris, France
    Hepatology 51:445-53. 2010
    ..Likewise, there was no improvement in the NAS score, ballooning, intralobular inflammation, fibrosis stage, or area of fibrosis with 2 additional years of RSG in the RSG-RSG group...
  9. ncbi request reprint Biochemical markers of fibrosis in patients with chronic hepatitis C: a comparison with prothrombin time, platelet count, and age-platelet index
    Robert P Myers
    Department of Gastroenterology and Hepatology, Groupe Hospitalier Pitie Salpetriere, Paris, France
    Dig Dis Sci 48:146-53. 2003
    ..In conclusion, an index of five biochemical markers accurately predicts significant hepatitis C-related fibrosis and is superior to traditional markers...
  10. ncbi request reprint Cryoglobulinemia is associated with steatosis and fibrosis in chronic hepatitis C
    David Saadoun
    Service de Médecine Interne and CNRS UMR 7087, Hopital Pitie Salpetriere, Paris, France
    Hepatology 43:1337-45. 2006
    ..001), and steatosis higher than 10% (P = .04). In conclusion, our study shows an independent association between cryoglobulin and steatosis as well as advanced fibrosis...
  11. doi request reprint Liver damage underlying unexplained transaminase elevation in human immunodeficiency virus-1 mono-infected patients on antiretroviral therapy
    Patrick Ingiliz
    Hepatology Department, AP HP, GH Pitié Salpétrière, Paris, France
    Hepatology 49:436-42. 2009
    ..Conclusions: HIV-infected patients on combined antiretroviral therapy with chronic transaminase elevation of unknown origin have a high rate of liver lesions, mostly consistent with NASH related to insulin resistance...
  12. doi request reprint A comparison of the fibrotic potential of nonalcoholic fatty liver disease and chronic hepatitis C
    Frederic Charlotte
    Universite Pierre et Marie Curie, Paris VI, Assistance Publique Hopitaux de Paris, Hopital Pitie Salpetriere, Service d Anatomie Pathologique
    Hum Pathol 41:1178-85. 2010
    ..The fibrotic potential of nonalcoholic fatty liver disease is as severe as that of chronic hepatitis C virus...
  13. pmc An accurate definition of the status of inactive hepatitis B virus carrier by a combination of biomarkers (FibroTest-ActiTest) and viral load
    Yen Ngo
    Service d Hepato Gastroenterologie, Groupe Hospitalier Pitie Salpetriere, Universite Paris VI, CNRS UMR 8149, Paris, France
    PLoS ONE 3:e2573. 2008
    ..We compared the 4-year prognostic value of combining FT-AT and viral load for a better definition of the inactive carrier status...
  14. pmc Performance of biomarkers FibroTest, ActiTest, SteatoTest, and NashTest in patients with severe obesity: meta analysis of individual patient data
    Thierry Poynard
    APHP UPMC Liver Center, Paris, France
    PLoS ONE 7:e30325. 2012
    ..The aim of this study was to perform an overview of 3 studies which assessed the performance of non-invasive markers of fibrosis (FibroTest), steatosis (SteatoTest) and steato-hepatitis (NashTest, ActiTest) in these patients...
  15. ncbi request reprint Ex vivo-expanded CD4+CD25+ immunoregulatory T cells prevent graft-versus-host-disease by inhibiting activation/differentiation of pathogenic T cells
    Aurélie Trenado
    Biologie et Thérapeutique des Pathologies Immunitaires, Hopital Pitie Salpetriere, Paris, France
    J Immunol 176:1266-73. 2006
    ..These latter cells permit the efficient and durable control of GVHD and favor immune reconstitution...
  16. pmc Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia
    Aurélie Trenado
    Biologie et Thérapeutique des Pathologies Immunitaires, Centre National de la Recherche Scientifique, Universite Pierre et Marie Curie, Unité Mixte de Recherche 7087, Hopital Pitie Salpetriere, 83 Boulevard de l hopital, F 75651 Paris Cedex 13, France
    J Clin Invest 112:1688-96. 2003
    ..These data suggest that recipient-type specific Treg's could be preferentially used in the control of GVHD in future clinical trials...
  17. pmc Diagnostic value of biochemical markers (FibroTest-FibroSURE) for the prediction of liver fibrosis in patients with non-alcoholic fatty liver disease
    Vlad Ratziu
    Hepato Gastroenterology, AP HP Groupe Hospitalier Pitié Salpétrière, Paris, France
    BMC Gastroenterol 6:6. 2006
    ..The aim of this study was to determine the diagnostic utility of non-invasive markers of fibrosis, validated in chronic viral hepatitis and alcoholic liver disease (FibroTest, FT), in patients with NAFLD...
  18. doi request reprint Rosiglitazone for nonalcoholic steatohepatitis: one-year results of the randomized placebo-controlled Fatty Liver Improvement with Rosiglitazone Therapy (FLIRT) Trial
    Vlad Ratziu
    Universite Pierre et Marie Curie Paris VI, Assistance Publique Hopitaux de Paris, Service d Hepatogastroenterologie, Paris, France
    Gastroenterology 135:100-10. 2008
    ..Nonalcoholic steatohepatitis (NASH) is a liver disease that complicates insulin-resistant states. This trial tested the efficacy and safety of rosiglitazone, an insulin-sensitizing agent, in patients with NASH...
  19. doi request reprint Erdheim-Chester disease
    Julien Haroche
    Department of Internal Medicine and French Reference Center for Rare Autoimmune and Systemic Diseases, Assistance Publique Hopitaux de Paris, Pitie Salpetriere Hospital, Paris, France
    Curr Rheumatol Rep 16:412. 2014
    ..A small number of patients harboring this mutation and with severe multisystemic and refractory ECD have been treated with vemurafenib, a BRAF inhibitor, which was proved very beneficial...
  20. doi request reprint Treatment of Erdheim-Chester disease with long-term high-dose interferon-α
    Baptiste Hervier
    Department of Internal Medicine, APHP, French Reference Center for Auto Immune Diseases, Hopital Pitie Salpetriere, and UPMC University of Paris 06, Paris, France
    Semin Arthritis Rheum 41:907-13. 2012
    ..Efficacy of standard doses of interferon-α-2a (IFNα) has been suggested in a small series but with variation, depending on the organs involved. Our aim was to report our single-center experience about the use of high-dose IFNα in ECD...
  21. doi request reprint In vivo activation of transferred regulatory T cells specific for third-party exogenous antigen controls GVH disease in mice
    Gaëlle H Martin
    UPMC Univ Paris 06, CNRS UMR7211, INSERM U959, Immunology Immunopathology Immunotherapy I3, Paris, France
    Eur J Immunol 43:2263-72. 2013
    ....
  22. ncbi request reprint Intrahepatic virus-specific IL-10-producing CD8 T cells prevent liver damage during chronic hepatitis C virus infection
    Michal Abel
    INSERM, U561 Equipe AVENIR, Paris, France
    Hepatology 44:1607-16. 2006
    ..Therapeutic modulation of the intrahepatic balance between specific and bystander CD8 T cells might be beneficial in patients with chronic hepatitis C...
  23. ncbi request reprint Portal lymphocytic infiltrate in alcoholic liver disease
    Magali Colombat
    Service Central d Anatomie Pathologique, Groupe Hospitalier Pitie Salpetriere, Paris, France
    Hum Pathol 33:1170-4. 2002
    ..These results suggest that lymphocytes may play a role in the pathogenesis of alcohol-induced liver fibrosis...
  24. doi request reprint Performances of Elasto-FibroTest(®), a combination between FibroTest(®) and liver stiffness measurements for assessing the stage of liver fibrosis in patients with chronic hepatitis C
    Thierry Poynard
    UPMC Liver Center, AP HP, 47 83, Boulevard de l Hopital, 75651 Paris Cedex 13, France
    Clin Res Hepatol Gastroenterol 36:455-63. 2012
    ..The combination between FibroTest(®) and LSM has never been assessed using methods assuming that biopsy is not a perfect gold standard...
  25. ncbi request reprint Efficacy of interferon-alpha for the treatment of Kaposi's sarcoma herpesvirus-associated uveitis
    Emmanuelle Brasnu
    Department of Ophthalmology, University of Paris VI, Pitie Salpetriere Hospital, Paris, France
    Am J Ophthalmol 140:746-8. 2005
    ..To report cases of uveitis that are associated with human herpesvirus-8 (HHV-8) and the impact of interferon-alpha therapy on their visual outcome...
  26. ncbi request reprint CD4+CD25+ regulatory/suppressor T cells prevent allogeneic fetus rejection in mice
    Guillaume Darrasse-Jèze
    Biologie et Thérapeutique des Pathologies Immunitaires, UPMC CNRS UMR 7087, Assistance Publique Hopitaux de Paris, Hopital Pitie Salpetriere, 83 Boulevard de l hopital, F75651 Paris Cedex 13, France
    Immunol Lett 102:106-9. 2006
    ..These observations were not made in the context of syngeneic pregnancies. Thus, T(reg) play a major role in maternal-fetal tolerance...
  27. doi request reprint Dramatic efficacy of vemurafenib in both multisystemic and refractory Erdheim-Chester disease and Langerhans cell histiocytosis harboring the BRAF V600E mutation
    Julien Haroche
    Department of Internal Medicine and French Reference Center for Rare Auto immune and Systemic Diseases, Assistance Publique Hopitaux de Paris AP HP, Pitie Salpetriere Hospital, Paris, France
    Blood 121:1495-500. 2013
    ..Treatment with vemurafenib, a newly approved BRAF inhibitor, should be considered for patients with severe and refractory BRAFV600E histiocytoses, particularly when the disease is life-threatening...
  28. ncbi request reprint High prevalence of BRAF V600E mutations in Erdheim-Chester disease but not in other non-Langerhans cell histiocytoses
    Julien Haroche
    Department of Internal Medicine and French Reference Center for Rare Auto immune and Systemic Diseases, Assistance Publique Hopitaux de Paris AP HP, Pitie Salpetriere Hospital, Paris, France
    Blood 120:2700-3. 2012
    ..Four patients with ECD died of disease. The high frequency of BRAF(V600E) in LCH and ECD suggests a common origin of these diseases. Treatment with vemurafenib should be investigated in patients with malignant BRAF(V600E) histiocytosis...
  29. ncbi request reprint Splenic metastases: clinicopathologic presentation, differential diagnosis, and pathogenesis
    Eva Comperat
    Service d Anatomie Pathologique, Hopital Pitie Salpetriere, Boulevard de l Hopital, 75013 Paris, France
    Arch Pathol Lab Med 131:965-9. 2007
    ..Splenic metastases occur in a context of multivisceral disseminated cancer or as a solitary lesion...
  30. doi request reprint Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection
    Bertrand Nalpas
    Unité d Hépatologie, Institut National de la Sante et de la Recherche Medicale, U567, Hopital Cochin, Paris, France
    Gut 59:1120-6. 2010
    ..Only a minority of patients with chronic hepatitis C virus (HCV) infection develops severe liver fibrosis, a process that may be controlled by human genetic factors...
  31. ncbi request reprint Identification of prognostic factors in post-transplant lymphoproliferative disorders
    Sylvain Choquet
    Departement d Hematologie, Hĵpital Pitié Salpêtrière, Paris, France
    Recent Results Cancer Res 159:67-80. 2002
    ..Studies on larger cohorts of patients need to be performed to confirm these data...
  32. doi request reprint Direct quantification of cell-associated HIV DNA in isolated rectal and blood memory CD4 T cells revealed their similar and low infection levels in long-term treated HIV-infected patients
    Benjamin Descours
    UPMC University Paris 06, INSERM, UMRs945, AP HP, Hopital Pitie Salpetriere, Laboratoire d Immunologie Cellulaire et Tissulaire, Paris, France
    J Acquir Immune Defic Syndr 62:255-9. 2013
    ....
  33. ncbi request reprint Late recurrence of a prostatic adenocarcinoma as a solitary splenic metastasis
    Eva Comperat
    Service d anatomie et cytologie pathologique, Hopital La Pitie, Paris, France
    Urol Int 78:86-8. 2007
    ..This case suggests that splenic metastasis might be the result of the growth of an early blood-borne micrometastasis within the spleen after a period of clinical latency...
  34. ncbi request reprint Bone marrow mesenchymal stem cells suppress lymphocyte proliferation in vitro but fail to prevent graft-versus-host disease in mice
    Muriel Sudres
    Biologie et Thérapeutique des Pathologies Immunitaires Université Pierre et Marie Curie Centre National de la Recherche Scientifique Unité Mixte de Recherche 7087, Paris, France
    J Immunol 176:7761-7. 2006
    ..Thus, in these murine models, experimental data do not support a significant immunosuppressive effect of MSCs in vivo for the treatment of GVHD...
  35. ncbi request reprint A study of bone marrow neoangiogenesis in chronic lymphocytic leukemia patients
    Claude Lesty
    Laboratory of Biologic Hematology, Hopital de la Pitie Salpetriere, Paris, France
    Anal Quant Cytol Histol 32:11-23. 2010
    ....
  36. doi request reprint Intractable ascites without mechanical vascular obstruction after orthotopic liver transplantation: etiology and clinical outcome of sinusoidal obstruction syndrome
    Kumiko Kitajima
    Department of Digestive, and Hepato Biliary Pancreatic Surgery, Liver Transplantation Unit, Hopitaux de Paris AP HP, Pitie Salpetriere Hospital, Universite Pierre et Marie Curie Paris VI, Paris, France
    Clin Transplant 24:139-48. 2010
    ..We speculate that the pre-existing diseased liver of the cadaver donor caused this serious complication, necessitating a second graft...
  37. ncbi request reprint High-dose therapy plus autologous hematopoietic stem cell transplantation for human immunodeficiency virus (HIV)-related lymphoma: results and impact on HIV disease
    Jean Gabarre
    Service d Hematologie, Hopital Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Paris, France
    Haematologica 89:1100-8. 2004
    ....
  38. ncbi request reprint Progression of liver fibrosis in women infected with hepatitis C: long-term benefit of estrogen exposure
    Vincent Di Martino
    Service d Hepato Gastroenterologie, GH Pitié Salpétrière, Paris, France
    Hepatology 40:1426-33. 2004
    ..Pregnancies may have a beneficial impact on the long-term progression of liver fibrosis...
  39. ncbi request reprint [Erdheim-Chester disease]
    Julien Haroche
    Service de Medecine Interne, Hopital Pitie Salpetriere, Paris
    Presse Med 36:1663-8. 2007
    ..The treatment, decided upon on a case-by-case basis at a specialist center, often begins with interferon alpha...
  40. doi request reprint Fatal outcome of deep-penetrating lower limb primary cutaneous anaplastic large cell lymphomas in two immunocompromised patients
    Stephane Barete
    Department of Dermatology, Hopital Tenon, Universite Pierre et Marie Curie Paris 6, Paris, France
    Acta Derm Venereol 89:627-30. 2009
    ..This information should be taken into consideration when making therapeutic choices...
  41. ncbi request reprint Sampling variability of liver biopsy in nonalcoholic fatty liver disease
    Vlad Ratziu
    Service d Hepatogastroenterologie, Groupe Hospitalier Pitie Salpetriere, Paris, France
    Gastroenterology 128:1898-906. 2005
    ..The aim of this study was to assess the sampling error of liver biopsy and its impact on the diagnosis and staging of NASH...
  42. doi request reprint Systemic perturbation of cytokine and chemokine networks in Erdheim-Chester disease: a single-center series of 37 patients
    Laurent Arnaud
    Departments of Internal Medicine, Pathology, Immunology and Virology, Hopital Pitie Salpetriere, AP HP Paris, France
    Blood 117:2783-90. 2011
    ....