Charles Chapron

Summary

Country: France

Publications

  1. doi Questioning patients about their adolescent history can identify markers associated with deep infiltrating endometriosis
    Charles Chapron
    Faculte de Medecine, Universite Paris Descartes, Assistance Publique Hopitaux de Paris, Groupe Hospitalier Universitaire Ouest, Centre Hospitalier, Paris, France
    Fertil Steril 95:877-81. 2011
  2. doi Ovarian endometrioma: severe pelvic pain is associated with deeply infiltrating endometriosis
    Charles Chapron
    Universite Paris Descartes, Sorbonne Paris Cité, Faculte de Medecine, Assistance Publique Hopitaux de Paris, Groupe Hospitalier Universitaire Ouest, Centre Hospitalier Universitaire Cochin Saint Vincent de Paul, Department of Gynecology Obstetrics II and Reproductive Medicine Professor Chapron, Paris, France
    Hum Reprod 27:702-11. 2012
  3. ncbi Associated ovarian endometrioma is a marker for greater severity of deeply infiltrating endometriosis
    Charles Chapron
    Université Paris Descartes V, Faculte de Medecine, Assistance Publique Hopitaux de Paris, Groupe Hospitalier Universitaire Ouest, CHU Cochin, Service de Gynécologie Obstétrique II et Médecine de la Reproduction, Paris, France
    Fertil Steril 92:453-7. 2009
  4. doi Severe ureteral endometriosis: the intrinsic type is not so rare after complete surgical exeresis of deep endometriotic lesions
    Charles Chapron
    Department of Obstetrics and Gynecology II and Reproductive Medicine, Universite Paris Descartes, Assistance Publique, Hopitaux de Paris AP HP, Groupe Hospitalier Universitaire GHU Ouest, Centre Hospitalier Universitaire CHU Cochin Saint Vincent de Paul, Paris, France
    Fertil Steril 93:2115-20. 2010
  5. doi Surgery for bladder endometriosis: long-term results and concomitant management of associated posterior deep lesions
    Charles Chapron
    Department of Gynecology, Obstetrics II and Reproductive Medicine, Universite Paris Descartes, Assistance Publique Hopitaux de Paris, Groupe Hospitalier Universitaire Ouest, Centre Hospitalier Universitaire Cochin, Saint Vincent de Paul, Pavillon Lelong, 82 avenue Denfert Rochereau, 75014 Paris, France
    Hum Reprod 25:884-9. 2010
  6. doi Smoking habits of 411 women with histologically proven endometriosis and 567 unaffected women
    Charles Chapron
    Service de Gynécologie Obstétrique II et Médecine de la Reproduction, Centre Hospitalier Universitaire Cochin Saint Vincent de Paul, Groupe Hospitalier Universitaire Ouest, Assistance Publique Hopitaux de Paris, Universite Paris Descartes, Paris, France
    Fertil Steril 94:2353-5. 2010
  7. doi Oral contraceptives and endometriosis: the past use of oral contraceptives for treating severe primary dysmenorrhea is associated with endometriosis, especially deep infiltrating endometriosis
    Charles Chapron
    Service de Gynécologie Obstétrique II and Reproductive Medicine, Universite Paris Descartes, Faculte de Medecine, Assistance Publique Hopitaux de Paris, Groupe Hospitalier Universitaire Ouest, Centre Hospitalier Universitaire Cochin Saint Vincent de Paul, Paris, France
    Hum Reprod 26:2028-35. 2011
  8. ncbi Operative management of deeply infiltrating endometriosis: results on pelvic pain symptoms according to a surgical classification
    Nicolas Chopin
    Assistance Publique, Hopitaux de Paris, Service de Gynécologie Obstétrique II, Unité de chirurgie gynécologique, CHU Cochin Port Royal, Paris, France
    J Minim Invasive Gynecol 12:106-12. 2005
  9. pmc The mTOR/AKT inhibitor temsirolimus prevents deep infiltrating endometriosis in mice
    Mahaut Leconte
    Laboratory of Immunology, Paris Descartes University, Hospital Cochin, Paris, France
    Am J Pathol 179:880-9. 2011
  10. doi Protein kinase inhibitors can control the progression of endometriosis in vitro and in vivo
    Charlotte Ngo
    Universite Paris Descartes, Faculte de Medecine, EA 1833 AP HP Hôpital Cochin, 75679 Paris Cedex 14, France
    J Pathol 222:148-57. 2010

Collaborators

Detail Information

Publications59

  1. doi Questioning patients about their adolescent history can identify markers associated with deep infiltrating endometriosis
    Charles Chapron
    Faculte de Medecine, Universite Paris Descartes, Assistance Publique Hopitaux de Paris, Groupe Hospitalier Universitaire Ouest, Centre Hospitalier, Paris, France
    Fertil Steril 95:877-81. 2011
    ..To investigate whether the clinical history, particularly of the adolescence period, contains markers of deeply infiltrating endometriosis (DIE)...
  2. doi Ovarian endometrioma: severe pelvic pain is associated with deeply infiltrating endometriosis
    Charles Chapron
    Universite Paris Descartes, Sorbonne Paris Cité, Faculte de Medecine, Assistance Publique Hopitaux de Paris, Groupe Hospitalier Universitaire Ouest, Centre Hospitalier Universitaire Cochin Saint Vincent de Paul, Department of Gynecology Obstetrics II and Reproductive Medicine Professor Chapron, Paris, France
    Hum Reprod 27:702-11. 2012
    ..The objective of this study was to evaluate the significance of severe preoperative pain for patients presenting with ovarian endometrioma (OMA)...
  3. ncbi Associated ovarian endometrioma is a marker for greater severity of deeply infiltrating endometriosis
    Charles Chapron
    Université Paris Descartes V, Faculte de Medecine, Assistance Publique Hopitaux de Paris, Groupe Hospitalier Universitaire Ouest, CHU Cochin, Service de Gynécologie Obstétrique II et Médecine de la Reproduction, Paris, France
    Fertil Steril 92:453-7. 2009
    ..To investigate whether an associated ovarian endometrioma is a marker for severity of deep infiltrating endometriosis (DIE)...
  4. doi Severe ureteral endometriosis: the intrinsic type is not so rare after complete surgical exeresis of deep endometriotic lesions
    Charles Chapron
    Department of Obstetrics and Gynecology II and Reproductive Medicine, Universite Paris Descartes, Assistance Publique, Hopitaux de Paris AP HP, Groupe Hospitalier Universitaire GHU Ouest, Centre Hospitalier Universitaire CHU Cochin Saint Vincent de Paul, Paris, France
    Fertil Steril 93:2115-20. 2010
    ..To evaluate the rate of intrinsic ureteral endometriosis in patients presenting with severe ureteral endometriosis...
  5. doi Surgery for bladder endometriosis: long-term results and concomitant management of associated posterior deep lesions
    Charles Chapron
    Department of Gynecology, Obstetrics II and Reproductive Medicine, Universite Paris Descartes, Assistance Publique Hopitaux de Paris, Groupe Hospitalier Universitaire Ouest, Centre Hospitalier Universitaire Cochin, Saint Vincent de Paul, Pavillon Lelong, 82 avenue Denfert Rochereau, 75014 Paris, France
    Hum Reprod 25:884-9. 2010
    ..The objectives of this study are to evaluate the rate of recurrence after partial cystectomy for patients presenting with bladder DIE and to outline the surgical modalities for handling associated posterior DIE nodules...
  6. doi Smoking habits of 411 women with histologically proven endometriosis and 567 unaffected women
    Charles Chapron
    Service de Gynécologie Obstétrique II et Médecine de la Reproduction, Centre Hospitalier Universitaire Cochin Saint Vincent de Paul, Groupe Hospitalier Universitaire Ouest, Assistance Publique Hopitaux de Paris, Universite Paris Descartes, Paris, France
    Fertil Steril 94:2353-5. 2010
    ....
  7. doi Oral contraceptives and endometriosis: the past use of oral contraceptives for treating severe primary dysmenorrhea is associated with endometriosis, especially deep infiltrating endometriosis
    Charles Chapron
    Service de Gynécologie Obstétrique II and Reproductive Medicine, Universite Paris Descartes, Faculte de Medecine, Assistance Publique Hopitaux de Paris, Groupe Hospitalier Universitaire Ouest, Centre Hospitalier Universitaire Cochin Saint Vincent de Paul, Paris, France
    Hum Reprod 26:2028-35. 2011
    ..We therefore compared various characteristics of OC use and the surgical diagnosis of endometriosis histologically graded as superficial peritoneal endometriosis (SUP), ovarian endometrioma (OMA) or deep infiltrating endometriosis (DIE)...
  8. ncbi Operative management of deeply infiltrating endometriosis: results on pelvic pain symptoms according to a surgical classification
    Nicolas Chopin
    Assistance Publique, Hopitaux de Paris, Service de Gynécologie Obstétrique II, Unité de chirurgie gynécologique, CHU Cochin Port Royal, Paris, France
    J Minim Invasive Gynecol 12:106-12. 2005
    ..To assess the results of complete surgical excision for patients with painful functional symptoms in a context of histologically proven deeply infiltrating endometriosis (DIE)...
  9. pmc The mTOR/AKT inhibitor temsirolimus prevents deep infiltrating endometriosis in mice
    Mahaut Leconte
    Laboratory of Immunology, Paris Descartes University, Hospital Cochin, Paris, France
    Am J Pathol 179:880-9. 2011
    ..mTOR/AKT inhibition by temsirolimus decreased endometriotic cell proliferation both in vitro and in vivo in a mouse model of DIE. Blocking the mTOR/AKT pathway offers new prospects for the treatment of DIE...
  10. doi Protein kinase inhibitors can control the progression of endometriosis in vitro and in vivo
    Charlotte Ngo
    Universite Paris Descartes, Faculte de Medecine, EA 1833 AP HP Hôpital Cochin, 75679 Paris Cedex 14, France
    J Pathol 222:148-57. 2010
    ..Our study shows that protein kinase inhibitors could be new candidates to treat endometriosis. However, further studies are needed to evaluate their effects and tolerability in humans...
  11. pmc Antiproliferative effects of cannabinoid agonists on deep infiltrating endometriosis
    Mahaut Leconte
    Laboratoire d Immunologie, Universite Paris Descartes, Paris, France
    Am J Pathol 177:2963-70. 2010
    ..Cannabinoid agonists exert anti-proliferative effects on stromal endometriotic cells linked to the inhibition of the Akt pathway. These beneficial effects of cannabinoid agonists on DIE have been confirmed in vivo...
  12. doi Antiproliferative effects of anastrozole, methotrexate, and 5-fluorouracil on endometriosis in vitro and in vivo
    Charlotte Ngo
    Faculte de Medecine, Universite Paris Descartes, EA 1833, ERTi, AP HP Hôpital Cochin, Paris, France
    Fertil Steril 94:1632-8.e1. 2010
    ..To investigate the effects of antiproliferative drugs (anastrozole, methotrexate, and 5-fluorouracil [5-FU]) on the proliferation of endometriotic cells in vitro and in vivo...
  13. doi Total laparoscopic hysterectomy for benign uterine pathologies: obesity does not increase the risk of complications
    Nicolas Chopin
    Department of Gynecology Obstetrics II and Reproductive Medicine, Universite Paris Descartes, Assistance Publique Hopitaux de Paris AP HP, Groupe Hospitalier Universitaire GHU Ouest, Centre Hospitalier Universitaire CHU Cochin Saint Vincent de Paul, Paris, France
    Hum Reprod 24:3057-62. 2009
    ..This study was designed to investigate the intra-operative characteristics and the risk of intra- and post-operative complications in cases of total laparoscopic hysterectomy (TLH) in overweight, obese and non-obese patients...
  14. doi In women with endometriosis anti-Müllerian hormone levels are decreased only in those with previous endometrioma surgery
    Isabelle Streuli
    Department of Obstetrics Gynaecology and Reproductive Medicine, Universite Paris Descartes, Sorbonne Paris Cité Assistance Publique Hôpitaux de Paris, CHU Cochin, 53, avenue de l Observatoire, 75014 Paris, France
    Hum Reprod 27:3294-303. 2012
    ..Are anti-Müllerian hormone (AMH) levels lower in women with endometriosis, notably those with endometriomas (OMAs) and deep infiltrating lesions, compared with controls without endometriosis?..
  15. doi Serum and peritoneal interleukin-33 levels are elevated in deeply infiltrating endometriosis
    Pietro Santulli
    Department of Gynecology Obstetrics II and Reproductive Medicine, Universite Paris Descartes, Sorbonne Paris Cité, Faculte de Medecine, AP HP, Hopital Cochin, 75679 Paris, France
    Hum Reprod 27:2001-9. 2012
    ..Interleukin 33 (IL-33) is a cytokine involved in fibrotic disorders. We have analyzed IL-33 levels in the sera and peritoneal fluids of women with various forms of endometriosis and investigated the correlation with disease activity...
  16. doi Genetic polymorphisms of DNMT3L involved in hypermethylation of chromosomal ends are associated with greater risk of developing ovarian endometriosis
    Bruno Borghese
    Department of Gynecology and Obstetrics 2, Cochin University Hospital, Paris Descartes University, Public Hospitals of Paris AP HP, Paris, France
    Am J Pathol 180:1781-6. 2012
    ..Our study constitutes a first milestone toward a plausible role of DNMT3L in the establishment of specific DNA methylation patterns in endometrioma...
  17. ncbi Deep infiltrating endometriosis: relation between severity of dysmenorrhoea and extent of disease
    Charles Chapron
    Service de Chirurgie Gynecologique, Clinique Universitaire Baudelocque, CHU Cochin, Saint Vincent de Paul, La Roche Guyon, 123, bd Port Royal 75079 Paris Cedex 14, France
    Hum Reprod 18:760-6. 2003
    ..Our aim was to evaluate the relationship between the severity of DM in women with posterior deep infiltrating endometriosis (DIE) and indicators of the extent of their disease...
  18. doi Deep infiltrating endometriosis is associated with markedly lower body mass index: a 476 case-control study
    Marie Christine Lafay Pillet
    Service de Gynécologie Obstétrique II, Universite Paris Descartes, Faculte de Medecine, Assistance Publique Hopitaux de Paris AP HP, Groupe Hospitalier Universitaire GHU Ouest, Centre Hospitalier Universitaire CHU Cochin Saint Vincent de Paul, France
    Hum Reprod 27:265-72. 2012
    ..We decided to evaluate the association between BMI and the different types of endometriosis, classified as superficial endometriosis (SUP), deep infiltrating endometriosis (DIE) and ovarian endometrioma (OMA)...
  19. doi [Intestinal endometriosis]
    Mahaut Leconte
    AP HP, Hopital Cochin, Universite Paris Descartes, Service de Chirurgie Digestive, hépatobiliaire et endocrinienne, 75679 Paris Cedex 14, France
    Presse Med 41:358-66. 2012
    ..There is currently no cure other than surgical removal of lesions. Medical treatments are based on a hormone used to block ovarian function...
  20. doi Absence of association between a functional polymorphism of ALOX15 gene and infertility in endometriosis
    Bruno Borghese
    Service de Gynécologie Obstétrique II et Médecine de la Reproduction, Universite Paris Descartes, Assistance Publique Hopitaux de Paris, CHU Cochin Saint Vincent de Paul, Paris, France
    Fertil Steril 91:1414-6. 2009
    ..In our study population, ALOX15 -292 C/T was not correlated either with the risk of developing an endometriosis or with the risk of infertility...
  21. pmc Increased serum oxidative stress markers in women with uterine leiomyoma
    Pietro Santulli
    Universite Paris Descartes, Sorbonne Paris Cité, Faculte de Medecine, AP HP, Hopital Cochin, Department of GynecologyObstetrics II and Reproductive Medicine, 75679 Paris, France
    PLoS ONE 8:e72069. 2013
    ..We have analysed oxidative stress markers (thiols, advanced oxidized protein products (AOPP), protein carbonyls and nitrates/nitrites) in preoperative sera from women with histologically proven uterine leiomyoma...
  22. ncbi Histologic appearance of endometriosis infiltrating uterosacral ligaments in women with painful symptoms
    Helene Bonte
    Service de Chirurgie Gynecologique, Clinique Universitaire Baudelocque, Cochin Port Royal, 123 Boulevard Port Royal, 75014 Paris, France
    J Am Assoc Gynecol Laparosc 9:519-24. 2002
    ..To describe the histologic appearance of deep endometriosis infiltrating the uterosacral ligaments (USL)...
  23. doi An update on the pharmacological management of endometriosis
    Isabelle Streuli
    Service de Gynecologie, obstétrique et médecine de la reproduction, Groupe hospitalier du centre Cochin Broca Hôtel Dieu, CHU Cochin, Paris, France
    Expert Opin Pharmacother 14:291-305. 2013
    ..The most commonly used medications are non-steroidal anti-inflammatory drugs, GnRH agonists, androgen derivatives such as danazol, combined oral contraceptive pills, progestogens and more recently the levonorgestrel intrauterine system...
  24. doi Sphingosine pathway deregulation in endometriotic tissues
    Pietro Santulli
    Universite Paris Descartes, Sorbonne Paris Cité, Faculte de Medecine, AP HP, Groupe Hospitalier Universitaire Ouest, Centre Hospitalier Universitaire Cochin Saint Vincent de Paul, Department of Gynecology Obstetrics II and Reproductive Medicine, Paris, France
    Fertil Steril 97:904-11. 2012
    ..To investigate key genes expression of the sphingosine-1-phosphate pathway in endometriotic tissues...
  25. doi Incidence and risk factors of bladder injuries during laparoscopic hysterectomy indicated for benign uterine pathologies: a 14.5 years experience in a continuous series of 1501 procedures
    Marie Christine Lafay Pillet
    Universite Paris Descartes, Assistance Publique Hopitaux de Paris, Groupe Hospitalier Universitaire Ouest, Centre Hospitalier Universitaire Cochin Saint Vincent de Paul, Service de Gynécologie Obstétrique II et Médecine de la Reproduction, Paris, France
    Hum Reprod 24:842-9. 2009
    ..The aim of this study was to evaluate the rate, the risk factors for bladder injuries in a series of 1501 laparoscopic hysterectomies indicated for benign uterine pathologies...
  26. ncbi Hormonal therapy deregulates prostaglandin-endoperoxidase synthase 2 (PTGS2) expression in endometriotic tissues
    Pietro Santulli
    Université Paris Descartes P S, B B, D d Z, C C, Sorbonne Paris Cité, Faculte de Medecine, Assistance Publique Hopitaux de Paris, Groupe Hospitalier Universitaire Ouest, Centre Hospitalier Universitaire Cochin St Vincent de Paul, Department of Gynecology Obstetrics II and Reproductive Medicine, 75679 Paris, France Université Paris Descartes P S, B B, D V, C C, Sorbonne Paris Cité, INSERM, Unité de Recherche U1016, Institut Cochin, Centre National de la Recherche Scientifique Unite Mixte de Recherche 8104, 75014 Paris, France Université Paris Descartes P S, F B, Sorbonne Paris Cité, Faculte de Medecine, Laboratoire d Immunologie, Équipe d Accueil 1833 Assistance Publique Hôpitaux de Paris, Hopital Cochin, 75679 Paris Cedex 14, France and Department of Gynecopathology J C N, I F, V A, Erasme University Hospital, Free University of Brussels, 1070 Brussels
    J Clin Endocrinol Metab 99:881-90. 2014
    ..Oral contraceptives are the treatment of choice for symptomatic endometriotic women. However the effects of oral contraceptives use and prostaglandin pathway in endometriotic women are actually still unknown...
  27. ncbi Management of ovarian endometriomas
    Charles Chapron
    Assistance Publique, Hopitaux de Paris AP HP, Clinique Universitaire Baudelocque, CHU Cochin Saint Vincent de Paul, Paris, France
    Hum Reprod Update 8:591-7. 2002
    ..In case of infertility, the management of endometriomas is controversial. Recurrent ovarian surgery is not recommended...
  28. ncbi Relation between severity of dysmenorrhea and endometrioma
    Nicolas Chopin
    Universite Rene Descartes, Paris V, Paris, France
    Acta Obstet Gynecol Scand 85:1375-80. 2006
    ..To evaluate the relationship between the severity of dysmenorrhea and endometrioma...
  29. ncbi Relation between pain symptoms and the anatomic location of deep infiltrating endometriosis
    Arnaud Fauconnier
    Service de Chirurgie Gynecologique, Clinique Universitaire Baudelocque, CHU Cochin, Saint Vincent de Paul, La Roche Guyon, Paris, France
    Fertil Steril 78:719-26. 2002
    ..To investigate whether specific types of pelvic pain are correlated with the anatomic locations of deeply infiltrating endometriosis (DIE)...
  30. doi Surgical management of cervical intraepithelial neoplasia in HIV-infected women
    Herve Foulot
    Département de gynécologie, Hopital Cochin, Paris, France
    Eur J Obstet Gynecol Reprod Biol 141:153-7. 2008
    ..We evaluated the efficacy of two excisional procedures, loop excision of the transformation zone (LLETZ) and electrosurgical conisation, in obtaining complete excision of CIN in HIV-infected patients...
  31. ncbi Preoperative work-up for patients with deeply infiltrating endometriosis: transvaginal ultrasonography must definitely be the first-line imaging examination
    Mathilde Piketty
    Department of Gynecology, Obstetrics II and Reproductive Medicine, Universite Paris Descartes, Paris, France
    Hum Reprod 24:602-7. 2009
    ..We compared the accuracy of TVUS and TRUS for diagnosing rectal wall involvement in patients presenting with histologically proved deeply infiltrating endometriosis (DIE)...
  32. doi Complete surgery for low rectal endometriosis: long-term results of a 100-case prospective study
    Bertrand Dousset
    Department of Digestive and Endocrine Surgery, University Hospital Cochin, Assistance Publique Hopitaux de Paris, Universite Paris Descartes, Paris, France
    Ann Surg 251:887-95. 2010
    ....
  33. doi Profibrotic interleukin-33 is correlated with uterine leiomyoma tumour burden
    Pietro Santulli
    Department of Gynecology Obstetrics II and Reproductive Medicine, Sorbonne Paris Cité, Faculte de Medecine, Universite Paris Descartes, AP HP, Hopital Cochin, 75679 Paris, France
    Hum Reprod 28:2126-33. 2013
    ..Are interleukin-33 (IL-33) serum levels higher in women with uterine leiomyoma compared with controls without leiomyoma?..
  34. ncbi Magnetic resonance imaging and endometriosis: deeply infiltrating endometriosis does not originate from the rectovaginal septum
    Charles Chapron
    Service de Chirurgie Gynecologique, Clinique Universitaire Baudelocque, Paris, France
    Gynecol Obstet Invest 53:204-8. 2002
    ..Our MR imaging results suggest that DIE lesions do not originate from the rectovaginal septum...
  35. ncbi Deeply infiltrating endometriosis: pathogenetic implications of the anatomical distribution
    Charles Chapron
    Service de Gynécologie Obstérique II, Unité de chirurgie gynécologique, Institut Cochin, IFR, Universite Paris V, Assistance Publique Hopitaux de Paris, Groupe Hospitalier Universitaire Ouest, France
    Hum Reprod 21:1839-45. 2006
    ..To investigate whether knowledge of the anatomical distribution of histologically proven deeply infiltrating endometriosis (DIE) lesions contributes to understanding the pathogenesis...
  36. doi Research resource: genome-wide profiling of methylated promoters in endometriosis reveals a subtelomeric location of hypermethylation
    Bruno Borghese
    département génétique et développement, Institut Cochin, 24 rue du Faubourg Saint Jacques, 75014 Paris, France
    Mol Endocrinol 24:1872-85. 2010
    ..We postulated that this original observation might participate to the chromosomal stability and protect the endometriotic lesion against malignancy...
  37. doi Urohemoperitoneum during pregnancy with consequent fetal death in a patient with deep endometriosis
    Ilda Chiodo
    Universite Paris V, Faculte de Medecine, Assistance Publique Hopitaux de Paris, Groupe Hospitalier Universitaire Ouest, CHU Cochin Saint Vincent de Paul, Service de Gynécologie Obstétrique II et Médecine de la Reproduction, Paris, France
    J Minim Invasive Gynecol 15:202-4. 2008
    ..Histologic examination confirmed presence of decidualized endometriosis at this site. Urohemoperitoneum during pregnancy is a rare but possible complication in women carrying deep peritoneal endometriotic nodules...
  38. doi HIV-positive patients undertaking ART have longer infertility histories than age-matched control subjects
    Pietro Santulli
    Department of Obstetrics, Gynecology, and Reproductive Medicine, Université Paris Descartes Assistance Publique Hôpitaux de Paris, CHU Cochin, Paris, France
    Fertil Steril 95:507-12. 2011
    ..To review 5 years of assisted reproductive treatments (ART) provided to couples affected by human immunodeficiency virus (HIV)...
  39. doi The value of growth hormone supplements in ART for poor ovarian responders
    Dominique DE Ziegler
    Université Paris Descartes Assistance Publique Hôpitaux de Paris, CHU Cochin, Department of Obstetrics, Gynecology, and Reproductive Medicine, Paris, France
    Fertil Steril 96:1069-76. 2011
    ..Although generally GH supplements did not increase controlled ovarian stimulation response or number of oocytes, the supplements improved pregnancy and live-birth rates-thus speaking for an effect on oocyte quality...
  40. ncbi Anatomical distribution of deeply infiltrating endometriosis: surgical implications and proposition for a classification
    Charles Chapron
    Service de Chirurgie Gynecologique, Service de Chirurgie Digestive and Service Central d Anatomie et Cytologie Pathologiques, Assistance Publique Hopitaux de Paris AP HP, Paris, France
    Hum Reprod 18:157-61. 2003
    ..Deeply infiltrating endometriosis (DIE) is recognized as a specific entity responsible for pain. The distribution of locations and their contribution to surgical management has not been previously studied...
  41. ncbi Measurement of hs-CRP is irrelevant to diagnose and stage endometriosis: prospective study of 834 patients
    Thibault Thubert
    Faculty of Medicine Université Paris Descartes, Sorbonne Paris Cité, Paris, France Department of Gynecology, Obstetrics, and Reproductive Medicine, Centre Hospitalier Universitaire Cochin of the Groupe Hospitalier Universitaire Ouest, Assistance Publique Hopitaux de Paris, Paris, France Electronic address
    Am J Obstet Gynecol 210:533.e1-533.e10. 2014
    ..Here, we assessed if the levels of high-sensitivity C-reactive protein (hs-CRP) in serum could constitute an effective method for detecting systemic inflammation during endometriosis...
  42. doi Markers of adult endometriosis detectable in adolescence
    Charles Chapron
    Université Paris Descartes Assistance Publique Hôpitaux de Paris, CHU Cochin, Department of OB GYN and Reproductive Medicine, Paris, France
    J Pediatr Adolesc Gynecol 24:S7-12. 2011
    ..Experimental verification of this insight, however, is needed before the concept that early diagnosis means lesser destructive surgery can be ascertained...
  43. doi Endometriosis and infertility: pathophysiology and management
    Dominique DE Ziegler
    Universite Paris Descartes, Centre Hospitalier Universitaire Cochin, Service de Gynécologie Obstétrique II et Médecine de la Reproduction, Paris, France
    Lancet 376:730-8. 2010
    ..Weighing up the relative advantages of surgery, medical treatment and ART are the foundations for a global approach to infertility associated with endometriosis...
  44. doi Multiplying recipients paired with oocyte donors optimizes the use of donated oocytes
    Dominique DE Ziegler
    Service de Gynécologie Obstétrique II, Hopital St Vincent de Paul, 82 Bd Denfert Rocherau, 75014 Paris, France
    Fertil Steril 95:1633-8. 2011
    ..To review donor-egg assisted reproductive technology (ART) activity using young fertile donors (<37 years of age) paired with multiple recipients...
  45. ncbi Surgical management of deeply infiltrating endometriosis: an update
    Charles Chapron
    Service de Chirurgie Gynecologique, Unité de Chirurgie, Clinique Universitaire Baudelocque, 123, boulevard Port Royal, CHU Cochin Saint Vincent de Paul, 75014 Paris, France
    Ann N Y Acad Sci 1034:326-37. 2004
    ..Further studies are needed to specify the place and modalities of medical treatments preoperatively and postoperatively...
  46. ncbi Ureteral complications from laparoscopic hysterectomy indicated for benign uterine pathologies: a 13-year experience in a continuous series of 1300 patients
    Franck Leonard
    Faculte de Medecine, Service de Gynécologie Obstétrique II et Médecine de la Reproduction, Unité de chirurgie gynécologique, Groupe Hospitalier Universitaire GHU Ouest, Paris, France
    Hum Reprod 22:2006-11. 2007
    ..The aim of this study was to evaluate the risk of ureteral injuries and to discuss how to avoid their occurence after laparoscopic hysterectomy indicated for benign uterine pathologies...
  47. doi Use of oral contraceptives in women with endometriosis before assisted reproduction treatment improves outcomes
    Dominique DE Ziegler
    Department of Obstetrics, Gynecology, and Reproductive Medicine, Université Paris Descartes Assistance Publique Hôpitaux de Paris, CHU Cochin, Paris, France
    Fertil Steril 94:2796-9. 2010
    ..Ovarian responsiveness to stimulation was not altered by 6 to 8 weeks' use of pre-ART OC, including in poor responders with endometriomas...
  48. doi Retrieving oocytes from small non-stimulated follicles in polycystic ovary syndrome (PCOS): in vitro maturation (IVM) is not indicated in the new GnRH antagonist era
    Dominique DE Ziegler
    Department of Obstetrics, Gynecology and Reproductive Medicine, Universite Paris Descartes, Paris Sorbonne Cité Assistance Publique Hôpitaux de Paris, CHU Cochin, Paris, France
    Fertil Steril 98:290-3. 2012
    ..This technique first offered in PCOS cannot be recommended today in this indication because the results do not match those of regular ART, and new GnRH antagonist and agonist-trigger protocols reliably prevent OHSS...
  49. doi Cancer and fecundity issues mandate a multidisciplinary approach
    Dominique DE Ziegler
    Universite Paris Descartes, Service de Gynécologie Obstétrique II et Médecine de la Reproduction, Paris, France
    Fertil Steril 93:691-6. 2010
    ..To review the existing options for preserving fecundity in young cancer patients, outlining the differences that exist in each individual cancer situation and how these affect our choice of fecundity-preserving measures...
  50. doi Genetic polymorphisms of matrix metalloproteinase 12 and 13 genes are implicated in endometriosis progression
    Bruno Borghese
    Universite Paris Descartes, Assistance Publique Hopitaux de Paris, Service de Gynécologie Obstétrique II, CHU Cochin Saint Vincent de Paul, Paris, France
    Hum Reprod 23:1207-13. 2008
    ..Matrix metalloproteinases (MMPs) may contribute to endometriosis. We tested whether eight functional polymorphisms of these genes could modify the risk of endometriosis...
  51. doi Peritoneal fluid flow influences anatomical distribution of endometriotic lesions: why Sampson seems to be right
    Alexandre Bricou
    Faculte de Medecine, AP HP de Paris, GHU Ouest, Service de Gynécologie Obstétrique II et Médecine de la Reproduction Pr Chapron, CHU Cochin Saint Vincent de Paul, Université Descartes Paris V, 82 avenue Denfert Rochereau, Paris, France
    Eur J Obstet Gynecol Reprod Biol 138:127-34. 2008
    ..The similarity in anatomical distribution of endometriomas, superficial and deeply invasive endometriotic lesions would tend to indicate a common origin for these different types of lesions...
  52. ncbi Anatomopathological lesions of bladder endometriosis are heterogeneous
    Charles Chapron
    Assistance Publique, Hopitaux de Paris AP HP, Service de Chirurgie Gynecologique, Clinique Universitaire Baudelocque, Paris, France
    Fertil Steril 78:740-2. 2002
    ..To present the anatomopathological characteristics of deep bladder endometriosis...
  53. doi Risk and safety management in infertility and assisted reproductive technology (ART): from the doctor's office to the ART procedure
    Dominique DE Ziegler
    Universite Paris Descartes, Paris Sorbonne Cité Department of Obstetrics, Gynecology, and Reproductive Medicine, Assistance Publique Hopitaux de Paris, CHU Cochin, Paris, France Electronic address
    Fertil Steril 100:1509-17. 2013
    ....
  54. pmc Reactive oxygen species controls endometriosis progression
    Charlotte Ngo
    Faculte de Medecine, Service de Gynécologie Obstétrique II et Médecine de la Reproduction, AP HP Hôpital Cochin, Paris, France
    Am J Pathol 175:225-34. 2009
    ..Human endometriotic cells display activated pERK, enhanced ROS production, and proliferative capability. Our murine model shows that antioxidant molecules could be used as safe and efficient treatments for endometriosis...
  55. doi Gene expression profile for ectopic versus eutopic endometrium provides new insights into endometriosis oncogenic potential
    Bruno Borghese
    Institut Cochin, Universite Paris Descartes, Centre National de la Recherche Scientifique Unite Mixte de Recherche 8104, Paris, France
    Mol Endocrinol 22:2557-62. 2008
    ..The study constitutes a noteworthy update of gene profiling in endometriosis, by delivering the most complete and reliable list of dysregulated genes to date...
  56. ncbi Ureteral endometriosis: the role of magnetic resonance imaging
    Corinne Balleyguier
    Adult Radiology Department, Necker Hospital, Paris, France
    J Am Assoc Gynecol Laparosc 11:530-6. 2004
    ..Magnetic resonance imaging is a useful preoperative tool for the diagnosis and assessment of ureteral endometriosis in rare cases when such lesions have been suspected...
  57. ncbi Routine clinical examination is not sufficient for diagnosing and locating deeply infiltrating endometriosis
    Charles Chapron
    Service de Chirurgie Gynecologique, Clinique Universitaire Baudelocque, C H U Cochin Port Royal, 123 bld Port Royal, 75014 Paris, France
    J Am Assoc Gynecol Laparosc 9:115-9. 2002
    ..To determine whether routine clinical examination is sufficient for the diagnosis and establishing the location of deeply infiltrating endometriosis (DIE)...
  58. ncbi High rate of recurrence of cervical intraepithelial neoplasia after surgery in HIV-positive women
    Isabelle Heard
    Institut National de la Santé et de la Recherche Médicale INSERM U430 and Unité d Immunologie Clinique, Hopital Europeen Georges Pompidou, Paris, France
    J Acquir Immune Defic Syndr 39:412-8. 2005
    ..Our study investigated the rate of recurrence of cervical intraepithelial neoplasia (CIN) in HIV-positive women after surgery in the era of highly active antiretroviral therapy (HAART)...
  59. ncbi Static and dynamic MRI features of the levator ani and correlation with severity of genital prolapse
    Yan Ansquer
    Hopital St Antoine, Assistance Publique Hopitaux de Paris, Universite Paris VI, Service de Gynecologie Obstetrique, 184 rue du Faubourg St Antoine, Paris, France
    Acta Obstet Gynecol Scand 85:1468-75. 2006
    ..To describe the static and dynamic MRI features of the levator ani, and evaluate whether they are associated with the MRI evaluation of the severity of genital prolapse...