Jean Marc Chapplain

Summary

Country: France

Publications

  1. doi request reprint The effects of a maintenance therapy with peg-interferon alpha-2a on liver fibrosis in HIV/HCV co-infected patients: a randomized controlled trial
    Jean Marc Chapplain
    Department of Infectious Diseases, Rennes University Hospital, Rennes 1 University, Rennes, France
    J Infect 67:313-21. 2013
  2. ncbi request reprint Mitochondrial abnormalities in HIV-infected lipoatrophic patients treated with antiretroviral agents
    Jean Marc Chapplain
    Infectious Diseases Department, Rennes University Hospital, Rennes, France
    J Acquir Immune Defic Syndr 37:1477-88. 2004
  3. doi request reprint Mitochondrial abnormalities in patients with HIV-HCV co-infection as compared to patients with HCV mono-infection
    Jean Marc Chapplain
    Rennes University Hospital, Rennes, France
    HIV Clin Trials 12:54-60. 2011
  4. ncbi request reprint Salvage therapy with amprenavir and ritonavir: prospective study in 17 heavily pretreated patients
    Cedric Arvieux
    Service des Maladies Infectieuses et Réanimation Médicale, Centre Hospitalier et Universitaire de Rennes, Rennes, France
    HIV Clin Trials 3:125-32. 2002
  5. ncbi request reprint The use of drug resistance algorithms and genotypic inhibitory quotient in prediction of lopinavir-ritonavir treatment response in human immunodeficiency virus type 1 protease inhibitor-experienced patients
    Anne Maillard
    Laboratoire de Virologie, Hopital Pontchaillou, 2 rue Henri Le Guilloux, 35 033 Rennes, France
    J Clin Virol 38:131-8. 2007
  6. ncbi request reprint Simultaneous quantitative assay of six HIV protease inhibitors, one metabolite, and two non-nucleoside reverse transcriptase inhibitors in human plasma by isocratic reversed-phase liquid chromatography
    Olivier Tribut
    Laboratoire de Pharmacologie Biologique, Hopital de Pontchaillou, Rennes, France
    Ther Drug Monit 24:554-62. 2002
  7. pmc Increasing incidence of severe Epstein-Barr virus-related infectious mononucleosis: surveillance study
    Pierre Tattevin
    Infectious Diseases and Intensive Care Unit, Pontchaillou University Hospital, Rennes, France
    J Clin Microbiol 44:1873-4. 2006
  8. ncbi request reprint Short-term decline in all-cause acquired infections with the routine use of a decontamination regimen combining topical polymyxin, tobramycin, and amphotericin B with mupirocin and chlorhexidine in the ICU: a single-center experience
    Christophe Camus
    1Service de Maladies Infectieuses et Réanimation Médicale, Hopital de Pontchaillou, CHU de Rennes, Universite de Rennes 1, Rennes, France 2Centre d Investigation Clinique CIC P INSERM 0203, Hopital de Pontchaillou, CHU de Rennes, Universite de Rennes 1, Rennes, France 3Laboratoire de Bactériologie, Virologie et Hygiene Hospitaliere, Hopital de Pontchaillou, CHU de Rennes, Universite de Rennes 1, Rennes, France 4Pôle Pharmacie Hospitalière, Hopital de Pontchaillou, CHU de Rennes, Rennes, France 5Service de Pharmacologie, Hopital de Pontchaillou, CHU de Rennes, Universite de Rennes 1, Rennes, France
    Crit Care Med 42:1121-30. 2014

Detail Information

Publications8

  1. doi request reprint The effects of a maintenance therapy with peg-interferon alpha-2a on liver fibrosis in HIV/HCV co-infected patients: a randomized controlled trial
    Jean Marc Chapplain
    Department of Infectious Diseases, Rennes University Hospital, Rennes 1 University, Rennes, France
    J Infect 67:313-21. 2013
    ..We hypothesized that, in Human Immunodeficiency Virus and Hepatitis C Virus (HIV/HCV) co-infected patients who did not respond to peg-interferon and ribavirin, a maintenance therapy with peg-interferon could induce fibrosis regression...
  2. ncbi request reprint Mitochondrial abnormalities in HIV-infected lipoatrophic patients treated with antiretroviral agents
    Jean Marc Chapplain
    Infectious Diseases Department, Rennes University Hospital, Rennes, France
    J Acquir Immune Defic Syndr 37:1477-88. 2004
    ..But physiopathology of loss of fat mass is still debated and the role of mitochondrial impairment is not clearly defined...
  3. doi request reprint Mitochondrial abnormalities in patients with HIV-HCV co-infection as compared to patients with HCV mono-infection
    Jean Marc Chapplain
    Rennes University Hospital, Rennes, France
    HIV Clin Trials 12:54-60. 2011
    ..Little is known about interactions between both viruses on mitochondrial metabolism...
  4. ncbi request reprint Salvage therapy with amprenavir and ritonavir: prospective study in 17 heavily pretreated patients
    Cedric Arvieux
    Service des Maladies Infectieuses et Réanimation Médicale, Centre Hospitalier et Universitaire de Rennes, Rennes, France
    HIV Clin Trials 3:125-32. 2002
    ..To evaluate the safety profile and efficacy of salvage regimens containing amprenavir (APV) 600 mg twice daily and ritonavir (RTV) 200 mg twice daily...
  5. ncbi request reprint The use of drug resistance algorithms and genotypic inhibitory quotient in prediction of lopinavir-ritonavir treatment response in human immunodeficiency virus type 1 protease inhibitor-experienced patients
    Anne Maillard
    Laboratoire de Virologie, Hopital Pontchaillou, 2 rue Henri Le Guilloux, 35 033 Rennes, France
    J Clin Virol 38:131-8. 2007
    ..Their uses in clinical practice may improve the benefit of protease inhibitor-based salvage therapy while reducing treatment toxicity and emergence of viral resistance...
  6. ncbi request reprint Simultaneous quantitative assay of six HIV protease inhibitors, one metabolite, and two non-nucleoside reverse transcriptase inhibitors in human plasma by isocratic reversed-phase liquid chromatography
    Olivier Tribut
    Laboratoire de Pharmacologie Biologique, Hopital de Pontchaillou, Rennes, France
    Ther Drug Monit 24:554-62. 2002
    ..The method has been validated extensively and has been in routine use in our laboratory for several months for drug monitoring in plasma samples from patients treated with antiretroviral drugs...
  7. pmc Increasing incidence of severe Epstein-Barr virus-related infectious mononucleosis: surveillance study
    Pierre Tattevin
    Infectious Diseases and Intensive Care Unit, Pontchaillou University Hospital, Rennes, France
    J Clin Microbiol 44:1873-4. 2006
    ..Between 1990 and 2004, 38 patients were admitted to our department with EBV-related IM. Two patients died. The annual incidence increased significantly (r = 0.623; P = 0.013)...
  8. ncbi request reprint Short-term decline in all-cause acquired infections with the routine use of a decontamination regimen combining topical polymyxin, tobramycin, and amphotericin B with mupirocin and chlorhexidine in the ICU: a single-center experience
    Christophe Camus
    1Service de Maladies Infectieuses et Réanimation Médicale, Hopital de Pontchaillou, CHU de Rennes, Universite de Rennes 1, Rennes, France 2Centre d Investigation Clinique CIC P INSERM 0203, Hopital de Pontchaillou, CHU de Rennes, Universite de Rennes 1, Rennes, France 3Laboratoire de Bactériologie, Virologie et Hygiene Hospitaliere, Hopital de Pontchaillou, CHU de Rennes, Universite de Rennes 1, Rennes, France 4Pôle Pharmacie Hospitalière, Hopital de Pontchaillou, CHU de Rennes, Rennes, France 5Service de Pharmacologie, Hopital de Pontchaillou, CHU de Rennes, Universite de Rennes 1, Rennes, France
    Crit Care Med 42:1121-30. 2014
    ..Because intubated patients are particularly at risk for acquired infections, we reassessed the impact of this protocol as a routine procedure to control acquired infections in the ICU...