Juan C Chachques

Summary

Country: France

Publications

  1. doi Myocardial Assistance by Grafting a New Bioartificial Upgraded Myocardium (MAGNUM trial): clinical feasibility study
    Juan C Chachques
    Department of Cardiovascular Surgery, Pompidou Hospital, Paris, France
    Ann Thorac Surg 85:901-8. 2008
  2. ncbi Myocardial assistance by grafting a new bioartificial upgraded myocardium (MAGNUM clinical trial): one year follow-up
    Juan C Chachques
    Department of Cardiovascular Surgery, Pompidou Hospital, Paris, France
    Cell Transplant 16:927-34. 2007
  3. doi Cellular cardiac regenerative therapy in which patients?
    Juan C Chachques
    Department of Cardiovascular Surgery, Pompidou Hospital, 20 rue Leblanc, 75015 Paris, France
    Expert Rev Cardiovasc Ther 7:911-9. 2009
  4. doi Heart transplantation following cardiomyoplasty: a biological bridge
    Juan C Chachques
    Department of Cardiovascular Surgery, Georges Pompidou European Hospital, 20 rue Leblanc, 75015 Paris, France
    Eur J Cardiothorac Surg 33:685-90. 2008
  5. doi Cardiac bioassist: results of the French multicenter cardiomyoplasty study
    Juan C Chachques
    Department of Cardiovascular Surgery, Pompidou Hospital, 75015 Paris, France
    Asian Cardiovasc Thorac Ann 17:573-80. 2009
  6. doi Association of electrostimulation with cell transplantation in ischemic heart disease
    Abdel Shafy
    Laboratory of Biosurgical Research, Pompidou Hospital, University of Paris, Paris, France
    J Thorac Cardiovasc Surg 138:994-1001. 2009
  7. ncbi Association between a cell-seeded collagen matrix and cellular cardiomyoplasty for myocardial support and regeneration
    Miguel Cortes-Morichetti
    Pompidou Hospital, Paris, France
    Tissue Eng 13:2681-7. 2007
  8. ncbi Angiogenic growth factors and/or cellular therapy for myocardial regeneration: a comparative study
    Juan C Chachques
    Department of Cardiovascular Surgery, European Hospital Georges Pompidou, 20 rue Leblanc, 75015 Paris, France
    J Thorac Cardiovasc Surg 128:245-53. 2004
  9. ncbi Cellular cardiomyoplasty: clinical application
    Juan C Chachques
    Department of Cardiovascular Surgery, European Hospital Georges Pompidou, University of Paris, Paris, France
    Ann Thorac Surg 77:1121-30. 2004
  10. ncbi Autologous human serum for cell culture avoids the implantation of cardioverter-defibrillators in cellular cardiomyoplasty
    Juan C Chachques
    Pompidou Hospital, University of Paris, France
    Int J Cardiol 95:S29-33. 2004

Collaborators

Detail Information

Publications18

  1. doi Myocardial Assistance by Grafting a New Bioartificial Upgraded Myocardium (MAGNUM trial): clinical feasibility study
    Juan C Chachques
    Department of Cardiovascular Surgery, Pompidou Hospital, Paris, France
    Ann Thorac Surg 85:901-8. 2008
    ..We evaluated the feasibility and safety of intrainfarct cell therapy associated with a cell-seeded collagen scaffold grafted onto infarcted ventricles...
  2. ncbi Myocardial assistance by grafting a new bioartificial upgraded myocardium (MAGNUM clinical trial): one year follow-up
    Juan C Chachques
    Department of Cardiovascular Surgery, Pompidou Hospital, Paris, France
    Cell Transplant 16:927-34. 2007
    ..quot; Efficacy and safety of this approach should be evaluated in a large randomized controlled trial...
  3. doi Cellular cardiac regenerative therapy in which patients?
    Juan C Chachques
    Department of Cardiovascular Surgery, Pompidou Hospital, 20 rue Leblanc, 75015 Paris, France
    Expert Rev Cardiovasc Ther 7:911-9. 2009
    ....
  4. doi Heart transplantation following cardiomyoplasty: a biological bridge
    Juan C Chachques
    Department of Cardiovascular Surgery, Georges Pompidou European Hospital, 20 rue Leblanc, 75015 Paris, France
    Eur J Cardiothorac Surg 33:685-90. 2008
    ..Heart transplantation was indicated afterwards in some CMP patients with recurrent heart failure symptoms. This study reviews the multicentric French experience with CMP followed by heart transplantation...
  5. doi Cardiac bioassist: results of the French multicenter cardiomyoplasty study
    Juan C Chachques
    Department of Cardiovascular Surgery, Pompidou Hospital, 75015 Paris, France
    Asian Cardiovasc Thorac Ann 17:573-80. 2009
    ..Dynamic cardiomyoplasty can be considered as a destination therapy or a mid- to long-term biological bridge to heart transplantation...
  6. doi Association of electrostimulation with cell transplantation in ischemic heart disease
    Abdel Shafy
    Laboratory of Biosurgical Research, Pompidou Hospital, University of Paris, Paris, France
    J Thorac Cardiovasc Surg 138:994-1001. 2009
    ..The purpose of this study is to evaluate myogenic cell transplantation in an ischemic heart model associated with cardiac resynchronization therapy...
  7. ncbi Association between a cell-seeded collagen matrix and cellular cardiomyoplasty for myocardial support and regeneration
    Miguel Cortes-Morichetti
    Pompidou Hospital, Paris, France
    Tissue Eng 13:2681-7. 2007
    ..This tissue engineering approach seems to improve the efficiency of cellular cardiomyoplasty and could emerge as a new therapeutic tool for the prevention of adverse remodeling and progressive heart failure...
  8. ncbi Angiogenic growth factors and/or cellular therapy for myocardial regeneration: a comparative study
    Juan C Chachques
    Department of Cardiovascular Surgery, European Hospital Georges Pompidou, 20 rue Leblanc, 75015 Paris, France
    J Thorac Cardiovasc Surg 128:245-53. 2004
    ..The goal of this study was to compare the effects of these techniques in an experimental model of myocardial infarct...
  9. ncbi Cellular cardiomyoplasty: clinical application
    Juan C Chachques
    Department of Cardiovascular Surgery, European Hospital Georges Pompidou, University of Paris, Paris, France
    Ann Thorac Surg 77:1121-30. 2004
    ..In this article we propose (1) a total autologous cell culture technique and procedures for cell delivery and (2) a clinical trial with appropriate endpoints structured to determine the efficacy of cellular cardiomyoplasty...
  10. ncbi Autologous human serum for cell culture avoids the implantation of cardioverter-defibrillators in cellular cardiomyoplasty
    Juan C Chachques
    Pompidou Hospital, University of Paris, France
    Int J Cardiol 95:S29-33. 2004
    ..We have hypothesized that contact of human cells with fetal bovine serum results after 3-week fixation of animal proteins on the cell surface, representing an antigenic substrate for immunological and inflammatory adverse events...
  11. doi Mesothelial cells vs. skeletal myoblasts for myocardial infarction
    Belahouel Bourahla
    INSERM Unit 698, Cardiovascular Remodeling Xavier Bichat Hospital, Paris, France
    Asian Cardiovasc Thorac Ann 18:153-60. 2010
    ..Mesothelial cells might be useful for biological revascularization in patients with ischemic heart disease...
  12. ncbi Cellular cardiomyoplasty for myocardial regeneration
    Juan C Chachques
    Department of Cardiovascular Surgery, Pompidou Hospital, 20 rue Leblanc, Paris 75015, France
    Asian Cardiovasc Thorac Ann 13:287-96. 2005
    ....
  13. ncbi From dynamic to cellular cardiomyoplasty
    Juan C Chachques
    Department of Cardiac Surgery, Ponpidou Hospital, Paris, France
    J Card Surg 17:194-200. 2002
    ..Healthy myoblasts and myotubes were observed 2 months after myocardial implantation. Clinical studies are now in progress...
  14. ncbi MRI evaluation of local myocardial treatments: epicardial versus endocardial (Cell-Fix catheter) injections
    Juan C Chachques
    Department of Cardiovascular Surgery, Pompidou and Bicetre Hospitals, Paris, France
    J Interv Cardiol 20:188-96. 2007
    ..Transepicardial injections were performed under direct surgical visualization whereas transendocardial injections were performed using electrophysiological guidance...
  15. doi Development of cardiac support bioprostheses for ventricular restoration and myocardial regeneration
    Abdel Shafy
    Department of Cardiovascular Surgery, Laboratory of Biosurgical Research, Pompidou Hospital, University Paris Descartes, Paris, France
    Eur J Cardiothorac Surg 43:1211-9. 2013
    ..The goal of this experimental study is to improve ventricular constraint therapy by associating stem cell intrainfarct implantation and a cell-seeded collagen scaffold as an interface between the constraint device and the epicardium...
  16. pmc Comparison of the effects of adenosine, inosine, and their combination as an adjunct to reperfusion in the treatment of acute myocardial infarction
    Abdel Shafy
    Laboratory of Biosurgical Research, Alain Carpentier Foundation, University Paris Descartes, 75015 Paris, France
    ISRN Cardiol 2012:326809. 2012
    ..The association of adenosine and inosine may contribute to reduce myocardial infarction morbidity and mortality rates...
  17. ncbi Right ventricular cardiomyoplasty: 10-year follow-up
    Juan C Chachques
    Department of Cardiovascular Surgery, Pompidou Hospital, Paris, France
    Ann Thorac Surg 75:1464-8. 2003
    ..The aim of this study is to present the first clinical report and long-term results of RV dynamic cardiomyoplasty applied in patients with RV failure caused by isolated RV cardiomyopathies...
  18. pmc Development of bioartificial myocardium by electrostimulation of 3D collagen scaffolds seeded with stem cells
    Kanwal Haneef
    University Paris Descartes, Pompidou Hospital, Laboratory of Biosurgical Research LRB, Paris
    Heart Int 7:e14. 2012
    ..Thus, MSC-derived differentiated cells by electrostimulation grafted in biological scaffolds might result in a convenient tissue engineering source for myocardial diseases...